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Home > Anti-aging Research > Devil's Claw.

Devil's Claw (Harpagophytum procumbens)

Specific Recommendations:

News & Research:

  • From Bush Medicine to Modern Phytopharmaceutical: A Bibliographic Review of Devil’s Claw (Harpagophytum spp.) -Pharmaceuticals 2021, 14(8) - "Devil’s claw (Harpagophytum spp., Pedaliaceae) is one of the best-documented phytomedicines. Its mode of action is largely elucidated, and its efficacy and excellent safety profile have been demonstrated in a long list of clinical investigation ... Close to 700 sources published over the course of two centuries were identified, confirmed, and cataloged. The purpose of the review is three-fold: to trace the historical milestones in devil’s claw becoming a modern herbal medicine, to point out gaps in the seemingly all-encompassing body of research, and to provide the reader with a reliable and comprehensive bibliography. The review covers aspects of ethnobotany, taxonomy, history of product development and commercialization, chemistry, pharmacology, toxicology, as well as clinical efficacy and safety. It is concluded that three areas stand out in need of further investigation. The taxonomical assessment of the genus is outdated and lacking. A revision is needed to account for intra- and inter-specific, geographical, and chemo-taxonomical variation, including variation in composition. Further research is needed to conclusively elucidate the active compound(s). Confounded by early substitution, intermixture, and blending, it has yet to be demonstrated beyond a reasonable doubt that both (or all) Harpagophytum spp. are equally (and interchangeably) safe and efficacious in clinical practice" - [Nutra USA] - See Devil's claw at Amazon.com.
  • New 'Biofactories' Produce Rare Healing Substances In Endangered Devil's Claw Plant - Science Daily, 8/16/09
  • Herbal Medicine May Be Effective for Low Back Pain - Medscape, 1/16/07 - "Short-term treatments with certain herbal medicines (including Devil's claw and willow bark) are effective for relief of acute low back pain"
  • 3 Herbal Medicines May Ease Back Pain - WebMD, 4/18/06 - "A 60-milligram daily dose of devil's claw also appeared to cut back pain as much as a 12.5-milligram daily dose of Vioxx, a painkiller no longer on the market due to a rise in the risk of cardiovascular events -- such as heart attackheart attack and strokestroke -- in some patients"
  • Patients Seek Natural Alternatives to NSAIDs - Clinical Psychiatry News, 7/05 - "The treatments significantly improved the pain level and joint mobility in study participants"
  • Playing the Devil’s (Claw) Advocate: Herbal Medicine for Back, Knee, and Hip Pain - New Hope Natural Media, 8/29/02
  • Natural Remedies for Osteoarthritis: Now, More than Ever - New Hope Natural Media, 8/15/02 - "Other natural substances that have been reported to relieve the symptoms of OA include vitamin E (600 to 1,200 IU per day), Devil's claw, cat's claw and ginger root"
  • Gentle Devil's Claw - Nutrition Science News, 4/01
  • Ease Gout Pain - Nutrition Science News, 7/99