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Anti-aging Research > Wild Yam
Wild Yam (Dioscorea villosa)
Specific Recommendations:
News & Research:
- Safe Hormone Strategy?
- Dr. Weil, 5/10/04
- Had Enough Wild Yams? -
Dr. Weil, 6/3/03
-
The Yam Cream Conundrum - Nutrition Science News, 2/01
-
The Replacements - Nutrition Science News, 8/99
Abstracts:
- DA-9801, a standardized
Dioscorea extract, improves memory function via the activation of nerve growth
factor-mediated signaling - Nutr Neurosci. 2020 Mar 27 -
"Nerve growth factor (NGF) is a neurotrophin that plays
a critical role in mammalian learning and memory functions ... Nerve growth
factor (NGF) is a neurotrophin that plays a critical role in mammalian learning
and memory functions. NGF also regulates neuronal cell differentiation and
neurite outgrowth by activating ERK/CREB signaling. This present study examined
the effects of a standardized Dioscorea extract (DA-9801) ... Mice were orally
treated with DA-9801 (10 and 100 mg/kg/day) once daily for 7 days. They were
subjected to passive avoidance test to evaluate memory functions ... DA-9801
treatment increased the NGF contents and neurite length, respectively. Mice with
DA-9801 administration showed memory enhancement in the passive avoidance test.
DA-9801 also increased newborn cell differentiation, neurite length, NGF
secretion, and ERK/CREB phosphorylation in the mouse hippocampus" - See
Dioscorea extract at Amazon.com.
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