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Home > Anti-aging Research > Postbiotics

Postbiotics

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News & Research:

  • WHAT ARE POSTBIOTICS? 5 HEALTH BENEFITS - Meridian Chiropractics - "Postbiotics are byproducts of the fermentation process carried out by probiotics in the intestine. In other words, as probiotics feed on prebiotics, postbiotics are produced. They are basically the “waste” of probiotics."
  • Short-chain fatty acid - Wiki - "Acetate, propionate, and butyrate are the three most common SCFAs"

Abstracts:

  • Role of the microbiota in hypertension and antihypertensive drug metabolism - Hypertens Res 2021 Dec 9 - "In this review, we provide insights into host-microbiota interactions and summarize the evidence supporting the importance of the microbiota in blood pressure (BP) regulation. Metabolites produced by the gut microbiota, especially short-chain fatty acids (SCFAs), modulate BP and vascular responses. Harmful gut-derived metabolites, such as trimethylamine N-oxide and several uremic toxins, exert proatherosclerotic, prothrombotic, and proinflammatory effects. High-salt intake alters the composition of the microbiota, and this microbial alteration contributes to the pathogenesis of salt-sensitive hypertension. In addition, the microbiota may impact the metabolism of drugs and steroid hormones in the host. The drug-metabolizing activities of the microbiota affect the pharmacokinetic parameters of antihypertensive drugs and contribute to the pathogenesis of licorice-induced pseudohyperaldosteronism. Furthermore, the oral microbiota plays a role in BP regulation by producing nitric oxide, which lowers BP via its vasodilatory effects. Thus, antihypertensive intervention strategies targeting the microbiota, such as the use of prebiotics, probiotics, and postbiotics (e.g., SCFAs), are considered new therapeutic options for the treatment of hypertension" - See Probiotic supplements at Amazon.com, Prebiotic supplements at Amazon.com and postbiotics at Amazon.com.