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Bitter Melon

Specific Recommendations:

• Bitter melon at Amazon.com

News & Research:

• Bitter Melon Extract May Have Potential to Fight Head, Neck Cancer - Science Daily, 11/18/13 - "In this study, the bitter melon extract treatment suppressed the head and neck cancer cell growth in the mouse model, reducing the growth of the tumor ... bitter melon extract regulated several pathways that helped reduce the head and neck cancer cell growth in the animal model. After a period of four weeks, Ray found that the growth and volume of the tumor had reduced ... Ray's initial research found that treatment with this natural substance halted the breast and prostate cancer cell growth, eventually stopping them from spreading" - See bitter melon at Amazon.com.
• Bitter melon juice prevents pancreatic cancer in mouse models - Science Daily, 3/12/13 - "Three years ago researchers showed the effect of bitter melon extract on breast cancer cells only in a Petri dish. This study goes much, much farther. We used the juice -- people especially in Asian countries are already consuming it in quantity. We show that it affects the glucose metabolism pathway to restrict energy and kill pancreatic cancer cells"
• Bitter melon extract decreased breast cancer cell growth - Science Daily, 2/23/10 - "Bitter melon extract, a common dietary supplement, exerts a significant effect against breast cancer cell growth and may eventually become a chemopreventive agent against this form of cancer ... the mechanism of bitter melon extract significantly decreased proliferation, that is, cell growth and division, and induced death in breast cancer cells"

Abstracts:

• Immunomodulatory Effects of Momordica charantia Extract in the Prevention of Oral Cancer - Cancer Prev Res (Phila). 2018 Mar 20 - "BME prevents the development of 4-nitronitroquinoline 1-oxide-induced oral dysplasia and squamous cell carcinoma (SCC) in an immunocompetent mouse model. Importantly, gene ontology and pathway analyses revealed an elevated expression of s100a9, IL23a, IL1β, and PDCD1/PD1 of immune system during oral cancer development, which was significantly suppressed by BME. Overall, this study demonstrates the potential clinical benefits of BME in preventing and delaying the progression of oral dysplasia to SCC" - See bitter melon extract at Amazon.com.