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Recent Longevity News for the week ending 4/5/17

High doses of vitamin C to improve cancer treatment passes human safety trial - Science Daily, 3/30/17 - "Clinical trials found that it is safe to regularly infuse brain and lung cancer patients with 800 -- 1000 times the daily recommended amount of vitamin C as a potential strategy to improve outcomes of standard cancer treatments ... This guarded optimism is based on the phase I trial data showing an increase in overall survival of 4-6 months in 11 glioblastoma multiforme patients (18-22 months) versus the 14-16 months survival typically seen with the standard treatment"

Why phosphate additives will be the next taboo ingredient - Washington Post, 3/30/17 - "In the form of phosphate compounds, phosphorus can also be added to food and beverages. These additives help baked goods rise, they act as emulsifiers in processed cheese and canned soup, they add flavor to cola and color to frozen french fries. They also can be added to meat, poultry and seafood to help the protein bind more water, making it juicier after freezing and reheating ... Our intake of phosphate additives in fast food and processed foods has more than doubled since the 1990s, from less than 500 mg a day to 1,000 mg a day. This is just from phosphate additives and doesn’t include foods that naturally contain phosphorus, yet it’s still higher than the recommended amount of phosphorus adults should get each day — 700 mg, according to the Institute of Medicine. The institute has also determined a safe upper limit for phosphorus and phosphate intake of 4,000 mg a day for healthy adults ... Emerging research has also linked higher intakes of phosphorus to a negative impact on bone health"

Larger doses of vitamin C may lead to a greater reduction in common cold duration - Science Daily, 3/30/17 - "The dose-response relationship in these two trials was also quite linear up to the levels of 6-8 g/day, thus it is possible that even higher doses may lead to still greater reductions in the duration of common cold" - See American Health Products - Ester C W/Citrus Bioflavonoids, 1000 mg, 180 veg tablets at Amazon.com.

Cortisol excess hits natural DNA process and mental health hard - Science Daily, 3/28/17 - "High concentrations of the stress hormone, Cortisol, in the body affect important DNA processes and increase the risk of long-term psychological consequences ... The condition is characterized by abdominal obesity, fat deposits in the face and neck, high blood pressure and diabetes. To a high extent, the affected individuals also risk suffering from chronic fatigue syndrome, anxiety, depression and cognitive impairment ... Even if the physical symptoms improve after an operation on the tumor, our previous studies show that the psychiatric problems largely often persist. Some patients will never return to working life and may not even venture out into society for everyday activities"

Does Vitamin D decrease risk of cancer? - Science Daily, 3/28/17 - "Participants were randomly assigned to take either 2000 international units (IU) of vitamin D3 and 1500 mg. of calcium or identical placebos daily for 4 years ... Women who were given vitamin D3 and calcium supplements had 30% lower risk of cancer ... Cedric Garland, a co-investigator at the University of California San Diego said "This is the most important scientific study of this century to date."" - See vitamin D at Amazon.com.

Gum disease, tooth loss may increase postmenopausal women’s risk of death - American Heart Association, 3/29/17 - "Our findings suggest that older women may be at higher risk for death because of their periodontal condition and may benefit from more intensive oral screening measures"

Astaxanthin compound found to switch on the FOX03 'Longevity Gene' in mice - Science Daily, 3/28/17 -"The Astaxanthin compound CDX-085 (developed by Cardax) showed the ability to significantly increase the expression of the FOXO3 gene, which plays a proven role in longevity ... We found a nearly 90% increase in the activation of the FOXO3 "Longevity Gene" in the mice fed the higher dose of the Astaxanthin compound CDX-085" - See BioAstin at Amazon.com.  Other recent studies on astaxanthin:

Children with poor vitamin B12 status early in life struggle more with tasks, recognition and interpreting feelings - Science Daily, 3/27/17 - "Small children with low levels of vitamin B12 had more difficulties solving cognitive tests, such as the ability to do puzzles, recognize letters and interpret other children's feelings ... the study suggests that vitamin B12 deficiency impair, or possibly delays, brain development in small children" - See vitamin B12 at Amazon.com.

High burden of Iodine deficiency found in Israel’s first national survey - Science Daily, 3/27/17 - "62% of school-age children and 85% of pregnant women fall below the WHO's adequacy range ... According to the researchers, the high burden of iodine insufficiency in Israel is a serious public health and clinical concern. By comparison to data from other countries with a similar extent of deficiency, these data suggest that there is a high risk of maternal and fetal hypothyroidism and impaired neurological development of the fetus in Israel ... Individuals can improve their iodine status through increased consumption of iodine-rich foods such as milk, dairy and salt water fish. They can also replace regular table salt with iodized salt ... only a small fraction of the salt sold in Israel is iodized, and it is sold at a much higher price than regular salt, although it does not need to be" - See Lugol's Iodine Solution(2 oz.) Twin Pack(2 bot.) at Amazon.com.

Concern over high US prescribing levels of common drug linked to dementia - Science Daily, 3/37/17 - "Oxybutynin is the least expensive antimuscarinic drug available, but its pharmacologic properties may cause significant cognitive side effects in elderly persons. Despite evidence of these side effects, physicians are not commonly checking for cognitive effects in those using these medications"

Night-time urination reduced by cutting salt in diet - Science Daily, 3/27/17 - "223 members of the group were able to reduce their salt intake from 10.7 gm per day to 8.0 gm/day. In this group, the average night-time frequency of urination dropped from 2.3 times/night to 1.4 times. In contrast, 98 subjects increased their average salt intake from 9.6 gm/night to 11.0 gm/night, and they found that the need to urinate increased from 2.3 times/night to 2.7 times/night"

Abstracts from this week:

Beet Root Juice: An Ergogenic Aid for Exercise and the Aging Brain - J Gerontol A Biol Sci Med Sci. 2016 Nov 9 - "beet root juice (BRJ) ... Older adults who exercised and consumed BRJ demonstrated greater consistency within the motor community and fewer secondary connections with the insular cortex compared with those who exercised without BRJ. The exercise + BRJ group had brain networks that more closely resembled those of younger adults, showing the potential enhanced neuroplasticity conferred by combining exercise and BRJ consumption" - See beet root powder at Amazon.com.

Beetroot Juice Supplementation Improves High-Intensity Intermittent Type Exercise Performance in Trained Soccer Players - Nutrients. 2017 Mar 22;9(3) - "Six days of BR ingestion effectively improves high-intensity intermittent type exercise performance in trained soccer players" - [Nutra USA] - See beet root powder at Amazon.com.

Mediterranean Diet Supplemented With Coenzyme Q10 Modulates the Postprandial Metabolism of Advanced Glycation End Products in Elderly Men and Women - J Gerontol A Biol Sci Med Sci. 2016 Oct 21 - "Med diet modulated redox-state parameters, reducing AGEs levels and increasing AGER1 and GloxI mRNA levels compared with the SFA diet. This benefit was accentuated by adding CoQ, in particular, in the postprandial state. Because elevated oxidative stress/inflammation and AGEs are associated with clinical disease in aging, the enhanced protection of a Med diet supplemented with CoQ should be assessed in a larger clinical trial in which clinical conditions in aging are measured" - See ubiquinol products at Amazon.com.

A low-dose, 6-week bovine colostrum supplementation maintains performance and attenuates inflammatory indices following a Loughborough Intermittent Shuttle Test in soccer players - Eur J Nutr. 2017 Mar 11 - "The aim of the study was to investigate the effect of a 6-week, low-dose bovine colostrum (BC) supplementation on exercise-induced muscle damage (EIMD) and performance decline in soccer players following the Loughborough Intermittent Shuttle Test (LIST) during a competitive season period ... randomized, placebo-controlled design, two groups of soccer players were allocated to a 3.2 g/day of whey protein ... Post-exercise EIMD may be reduced and performance better maintained by a low dose of BC administration following LIST in soccer players" - See Colostrum Direct Liquid 125ml by L R at Amazon.com (the brand used in the study, see the Nutra USA article).

Neat Tech Stuff / "How To's":

JerryRigEverything YouTube review on Ztylus Stinger USB Emergency Escape Tool - See Ztylus Stinger USB Emergency Escape Tool at Amazon.com

Health Focus (Gallstones):