 |
|
|
|
|
|
|
|
|
|
|
Recent Longevity News for the week ending 2/4/15: Expert panel recommends new sleep durations - Science Daily, 2/2/15 - "Younger adults (18-25): Sleep range is 7-9 hours (new age category) ... Adults (26-64): Sleep range did not change and remains 7-9 hours ... Older adults (65+): Sleep range is 7-8 hours (new age category)" Ways to Age-Proof Your Brain - ABC News, 2/2/15 - "Take dance lessons ... Play an instrument ... Learn a foreign language ... Play chess ... Read more of less ... Change your font ... Write about your stress"
Older adults: Double your protein to build more muscle - Science Daily, 1/30/15 - "Current US recommendations for daily dietary protein intake are 0.8 grams/kilogram of body weight (roughly 62 g of protein per day for a 170-pound person). Previous research has shown that older adults need a protein intake of at least 0.40 g/kg of body weight at each meal (roughly 31 g of protein per meal or 93 g per day for a 170-pound person) to encourage maximum protein synthesis. This represents a significantly higher amount of protein than the recommended dietary allowance (RDA) suggests ... The research team studied 20 healthy adults between 52-75 years of age, randomly assigning them to one of four groups over a four-day test period ... while the distribution of protein across meals did not make a significant impact, total amount of protein consumed" Totality of trials data confirm Tamiflu reduces length of symptoms, complications, and hospital admissions from influenza - Science Daily, 1/30/15 - "oseltamivir significantly reduces the risk of influenza complications requiring antibiotics (such as pneumonia) and hospitalisations in adults infected with influenza ... treating adults with laboratory-confirmed influenza with oseltamivir reduced the duration of symptoms by 21% compared with placebo (from 123 hours to 98 hours) ... oseltamivir reduced the risk of lower respiratory tract infections requiring antibiotics more than 48 hours after study entry by 44% compared with placebo (4.9% vs 8.7%), and hospital admission for any cause by 63% (0.6% vs 1.7%) in adults with laboratory-confirmed influenza"
Chondroitin/Glucosamine
Reduced Pain in Knee Arthritis in RCT - Medscape, 1/30/15 -
"a combination glucosamine/chondroitin
sulfate product produced a 50.1% decrease in Western Ontario and McMaster
OA index (WOMAC) pain, which is comparable to
the 50.2% decrease seen in patients randomly assigned to receive
celecoxib ... Patients received either
chondroitin sulfate 400 mg plus glucosamine hydrochloride 500 mg (CS+GH;
Droglican, Bioibérica SA) three times a day or celecoxib 200 mg every day for 6
months" - See
glucosamine chondroitin formulas at Amazon.com
Pharmacological Potential
of Tocotrienols: A Review - Medscape, 1/29/15 - "In
contrast to αT, despite no evidence that deficiency of other
vitamin E forms
would result in obvious clinical symptoms, accumulating evidence suggests that
γT, δT, and tocotrienols seem to have unique properties that are superior to αT
and relevant to prevention and therapy against chronic diseases even under
conditions with adequate αT status. It is noteworthy that these bioactivities of
tocopherols and tocotrienols including anti-inflammatory properties have been
identified by mechanistic studies and subsequently substantiated in some
preclinical models as well as clinical studies ... Hence, tocotrienols possess neuroprotective, antioxidant, anti-cancer and cholesterol lowering properties.
Tocotrienols are thought to have more potent antioxidant and free radical
scavenging properties due to their better distribution in the lipid layers of
the cell membrane. In spite of the promising potential, the experimental
analysis of tocotrienols accounts for only a small portion of vitamin E
research" - See
Jarrow FamilE (contains all eight members of the vitamin E family, includes
Tocomin) at Amazon.com Saying No to Cannabis Improves Bipolar Outcomes - Medscape, 1/19/15 - "quitting cannabis during acute treatment for manic/mixed bipolar episodes and refraining from use during a maintenance treatment period significantly improved function and lowered the risk for recurrence ... Our results also showed that patients who continued to use cannabis had worse outcomes than those who either stopped using cannabis or had never used it ... patients that continued using cannabis had more suicide attempts than those that quit or those who never used cannabis" Researchers find hormone that increases the sex drive of mice - Science Daily, 1/27/15 - "when mice receive a supplement of ghrelin, they increase their sexual activity and their efforts to find a partner" - Note: It doesn't sound like a cure to me. Ghrelin is the hunger hormone. So you pack on the pounds, plugging up your arteries and you're back where you started. Plus it may have just been the increase in calories that caused the increase in sexual activity in the first place.
Many
U.S. consumers do not use a food thermometer when cooking poultry, despite
hazardous risks - Science Daily, 1/16/15 - "fewer than two-thirds of
consumers own a food thermometer, and less than 10 percent of food thermometer
owners actually use it to check for doneness of all types of poultry ...
Pathogens, such as Salmonella and Campylobacter, may be present on raw poultry.
Using a food thermometer is the only reliable way to ensure food is cooked to a
safe internal temperature to destroy any harmful bacteria that may present. USDA
recommends that consumers cook all poultry to a safe minimum internal
temperature of 165°F" - Note: I was surprise that the number that use them
is so few. Here's my favorite. It's simple and easy to read: MeasuPro DCT250 Ultra-Fast Instant Read Digital Cooking Thermometer with Timer, Silver Abstracts from this week:
Resveratrol
protects against doxorubicin-induced cardiotoxicity in aged hearts through the
SIRT1-USP7 axis - J Physiol. 2015 Jan 13 - "A
compromised cardiac function is often seen in elderly cancer patients receiving
doxorubicin therapy ...
resveratrol ameliorates doxorubicin-induced
cardiotoxicity in the aged hearts through the restoration of SIRT1 activity to
attenuate USP7-related catabolic/pro-apoptotic signalling" - See
ReserveAge Resveratrol Vegetarian Capsules, 500 Mg, 60-Count
at Amazon.com
Omega-3
fatty acids protect from diet-induced obesity, glucose intolerance and adipose
tissue inflammation through PPARγ dependent and independent actions - Mol
Nutr Food Res. 2015 Jan 31 - "high-fat diet (HFD) ...
High endogenous n-3 fatty acid levels protect
from HFD obesity, glucose intolerance, and adipose tissue inflammation" -
See
fish oil supplements at Amazon.com
Resveratrol
restores the circadian rhythmic disorder of lipid metabolism induced by
high-fat-diet in Mice - Biochem Biophys Res Commun. 2015 Jan 29 -
"resveratrol reduced
lipogenesis and ultimately normalized rhythmic expression of plasma lipids,
possibly via its action on clock machinery" - See
ReserveAge Resveratrol Vegetarian Capsules, 500 Mg, 60-Count
at Amazon.com Glycemic load and coronary heart disease in a Mediterranean population: The EPIC Greek cohort study - Nutr Metab Cardiovasc Dis. 2014 Dec 11 - "High adherence to MD with low/moderate GL was associated with lower risk of CHD incidence (HR = 0.61, CI: 0.39-0.95) and mortality (HR = 0.47, 95% CI: 0.23-96)"
Vitamin C
supplementation in the critically ill patient - Curr Opin Clin Nutr Metab
Care. 2015 Jan 29 - "Restoration of normal plasma levels in
inflammatory
patients requires the administration of 3 g/day for several days ... The recent
research on the modulation of oxidative stress and endothelial protection offer
interesting therapeutic perspectives, based on the biochemical evidence, with
limited or even absent side-effects" - See
American Health Products - Ester C W/Citrus Bioflavonoids, 1000 mg, 180 veg tablets at Amazon.com
Vitamin D
supplementation in the ICU patient - Curr Opin Clin Nutr Metab Care. 2015
Jan 29 - "Both biological and observational studies support the role of
vitamin
D deficiency in adverse critical illness outcomes. Interventional trials of
critically ill patients show that to improve vitamin D status, high-dose vitamin
D3 is required. Critically ill patients have a relatively blunted response to
vitamin D supplementation compared to the general outpatient population"
- See
vitamin D at Amazon.com
Natural
vitamin C intake and the risk of head and neck cancer: A pooled analysis in the
International Head and Neck Cancer Epidemiology Consortium - Int J Cancer.
2014 Dec 8 - "Higher intakes of
vitamin C were inversely related to
oral and pharyngeal (OR = 0.54, 95%
CI: 0.45-0.65, for the fifth quintile category versus the first one, p for
trend<0.001) and laryngeal cancers (OR = 0.52, 95% CI: 0.40-0.68, p for
trend = 0.006), although in the presence of heterogeneity among studies for both
sites. Inverse associations were consistently observed for the anatomical
subsites of oral and pharyngeal cancer, and across strata of age, sex,
education, body mass index, tobacco, and alcohol, for both cancer sites"
- See
American Health Products - Ester C W/Citrus Bioflavonoids, 1000 mg, 180 veg tablets at Amazon.com
Probiotic
supplementation prevents high-fat, overfeeding-induced insulin resistance in
human subjects - Br J Nutr. 2015 Jan 29:1-7 - "The
purpose of the present study was to determine whether
probiotic supplementation (Lactobacillus casei Shirota (LcS)) prevents
diet-induced insulin resistance in human subjects. A total of seventeen healthy
subjects were randomised to either a probiotic (n 8) or a control (n 9) group
... Glucose AUC values increased by 10 % (from 817 (se 45) to 899 (se 39) mmol/l
per 120 min, P< 0.05) and whole-body insulin sensitivity decreased by 27 % (from
5.3 (se 1.4) to 3.9 (se 0.9), P< 0.05) in the control group, whereas normal
insulin sensitivity was maintained in the probiotic group (4.4 (se 0.8) and 4.5
(se 0.9) before and after overeating, respectively (P>0.05). These results
suggest that probiotic supplementation may be useful in the prevention of
diet-induced metabolic diseases such as type 2 diabetes" - See
probiotic products at Amazon.com
Green tea
changes serum and liver metabolomic profiles in mice with high-fat diet-induced
obesity - Mol Nutr Food Res. 2015 Jan 28 - "Green
tea (GT) consumption helps to prevent and control obesity by stimulating
hepatic lipid metabolism ... HFD-induced abnormal mitochondrial β-oxidation was
moderated by the consumption of caffeine- and theanine-enriched GT ... Results
of LC/MS-based metabolomic analysis of obese mice showed changes associated with
abnormal lipid and energy metabolism, which were alleviated by GT intake,
indicating the mechanism underlying the anti-obesity effects of GT" - See
green tea extract at Amazon.com Immune-mediated antitumor effect by type 2 diabetes drug, metformin - Proc Natl Acad Sci U S A. 2015 Jan 26 - "Metformin, a prescribed drug for type 2 diabetes, has been reported to have anti-cancer effects; however, the underlying mechanism is poorly understood. Here we show that this mechanism may be immune-mediated. Metformin enabled normal but not T-cell-deficient SCID mice to reject solid tumors. In addition, it increased the number of CD8+ tumor-infiltrating lymphocytes (TILs) and protected them from apoptosis and exhaustion characterized by decreased production of IL-2, TNFα, and IFNγ. CD8+ TILs capable of producing multiple cytokines were mainly PD-1-Tim-3+, an effector memory subset responsible for tumor rejection" - See metformin at The Antiaging Store. Health Focus (Acetyl-L-Carnitine):
|
|||
|
|
). That’s in addition to listening
to it while on my treadmill for an hour and a half per day not to
mention listening to the Mandarin dubbed movies while working on my
computer. See
,
,
,
and 
.
The way your remove the region code on these movies is to use
something like 
.
.