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Home >
Anti-aging Research > Sesame
Sesame Seed
Specific Recommendations:
News & Research:
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Sesame & Rice Bran Oil, Yogurt Help Blood Pressure - WebMD, 9/19/12 -
"The first study showed a sesame and rice bran oil
blend reduced blood pressure almost as well as a commonly used medication.
And the second study found that people who routinely eat yogurt are less
likely to develop high blood pressure ... In the yogurt study, about 2,000
adults without high blood pressure were followed for 14 years. The
researchers found that participants were 31% less likely to develop high
blood pressure if more than 2% of their daily calories came from yogurt"
- See sesame seed oil at Amazon.com
 and
rice bran oil at Amazon.com.
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Sesame lignan may help control blood pressure - Nutra USA, 3/31/05 -
"sesamin, one of the lignans most abundant in sesame
seed and oil, helps to control high blood pressure"
Abstracts:
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Sesamolin Attenuates Kidney
Injury, Intestinal Barrier Dysfunction, and Gut Microbiota Imbalance in High-Fat
and High-Fructose Diet-Fed Mice - J Agric Food Chem 2023 Jan 11 -
"This
study investigated the effects of sesamolin on kidney injury, intestinal barrier
dysfunction, and gut microbiota imbalance in high-fat and high-fructose (HF-HF)
diet-fed mice and explored the underlying correlations among them. The results
indicated that sesamolin suppressed metabolic disorders and increased renal
function parameters. Histological evaluation showed that sesamolin mitigated
renal epithelial cell degeneration and brush border damage ... Thus, sesamolin
may be a potential dietary supplement for protection against obesity-associated
kidney injury" - See
sesame seed oil at Amazon.com.
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Sesamol Augments
Paclitaxel-Induced Apoptosis in Human Cervical Cancer Cell Lines - Nutr
Cancer 2022 May 31 - "Sesamol treatment before paclitaxel exposure enhanced the
apoptotic cell death in the HeLa cell lines. The results of the present study
were in support of the usage of natural medicinal compounds for clinical
chemotherapy after systematic animal experimentations"
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Sesamol
- Wikipedia - "Sesamol is a natural
organic compound which is a component of sesame seeds and
sesame oil. It is a white crystalline solid that is a
derivative of phenol" - See
sesame seed oil at Amazon.com.
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The effect
of sesame, canola, and sesame-canola oils on cardiometabolic
risk factors in overweight adults: a three-way randomized
triple-blind crossover clinical trial - Phytother Res 2022
Jan 23 - "77 overweight adults were
randomized to replace their regularly consumed oils with canola
(CO), sesame (SO), and sesame-canola oils (SCO, 40% SO, and 60%
CO) in three 9-week phases ... SO significantly reduced serum
alkaline aminotransferase (ALT) compared to CO (p ≤ 0.05) in all
participants, increased serum urea compared to SCO in males, and
decreased serum alkaline phosphatase compared to other oils in
males, and improved serum high-density lipoprotein cholesterol
(HDL-C) and triglycerides (TG) compared to SCO, and eGFR
compared with CO in females (p ≤ 0.05). Canola oil significantly
improved serum Apo A1 and APO B/A ratio compared with SO, in
males (p ≤ 0.05). Sesame-canola oil significantly reduced serum
urea compared to other oils in all participants (p ≤ 0.05).
Sesame oil and SCO might beneficially affect serum ALT and urea,
respectively. Intervention oils might have different
cardiometabolic effects in each gender"
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Effects of Dietary
Supplementation of Astaxanthin and Sesamin on Daily Fatigue: A Randomized,
Double-Blind, Placebo-Controlled, Two-Way Crossover Study - Nutrients. 2018
Feb 28;10(3) - "astaxanthin and sesamin (AS) ... Secondary outcomes included
other subjective feelings, work efficiency, autonomic nerve activity, levels of
an oxidative stress marker (plasma phosphatidylcholine hydroperoxide (PCOOH))
and safety. AS supplementation was associated with significantly improved
recovery from mental fatigue compared with placebo. Increased PCOOH levels
during mental and physical tasks were attenuated by AS supplementation. No
differences between AS and placebo were detected in secondary outcomes, and no
adverse effects of AS supplementation were observed. In conclusion, AS
supplementation may be a candidate to promote recovery from mental fatigue which
is experienced by many healthy people" - [Nutra
USA] - See
astaxanthin at Amazon.comand
sesamin at Amazon.com.
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Antihypertensive and antioxidant effects of dietary black sesame meal in
pre-hypertensive humans - Nutr J. 2011 Aug 9;10(1):82 -
"Twenty-two women and eight men (aged 49.8 +/- 6.6
years) with prehypertension were randomly divided into two groups, 15 subjects
per group. They ingested 2.52 g black sesame meal capsules or placebo capsules
each day for 4 weeks ... malondialdehyde (MDA) ... The results showed that
4-week administration of black sesame meal significantly decreased systolic BP
(129.3 +/- 6.8 vs. 121.0 +/- 9.0 mmHg, P < 0.05) and MDA level (1.8 +/- 0.6 vs.
1.2 +/- 0.6 micromol/L, P < 0.05), and increased vitamin E level (29.4 +/- 6.0
vs. 38.2 +/- 7.8 micromol/L, P < 0.01). In the black sesame meal group, the
change in systolic BP tended to be positively related to the change in MDA (R =
0.50, P = 0.05), while the change in diastolic BP was negatively related to the
change in vitamin E (R = -0.55, P <0.05)" - Note: An 8.3 point drop in
systolic seems impressive. That's about what you get from medication plus it's
systolic that most have a problem with.
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Sesame ingestion affects sex hormones, antioxidant status, and blood lipids in
postmenopausal women - J Nutr. 2006 May;136(5):1270-5 -
"sesame ingestion benefits postmenopausal women by
improving blood lipids, antioxidant status, and possibly sex hormone status"
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Impact of sesame oil on nifedipine in modulating oxidative stress and
electrolytes in hypertensive patients - Asia Pac J Clin Nutr.
2004;13(Suppl):S107 -
"The consumption of sesame oil remarkably reduced
the (systolic and diastolic blood pressure from 166 +/- 4.2 and 101 +/- 3.1
to 134.2 +/- 3.4 and 84.6 +/- 3.0 respectively) blood pressure"
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