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Recent Longevity News for the seven days ending 10/29/03:

Research Finds Tumor Preventive Qualities, Damage Reversal, In Green Tea - Intelihealth, 10/29/03 - "EGCG (epigallocatchin-3-gallate) is the most abundant and active chemopreventive agent in green tea, and has been associated with reduced risk of breast, pancreatic, colon, esophageal and lung cancers in humans ... At the same time, we see the value of green tea polyphenols in reducing excretion of 8-OHdG. All of this is good news for the prevention and early detection of liver cancer" - See iHerb or Vitacosticon green tea products.

Fruit Ingredients Affect Skin Cancer in Mice - Yahoo, 10/29/03 - "They measured levels of a protein called survivin, which is overproduced in cancer cells but missing in normal adult cells. The resveratrol-treated mice produced less survivin"

Green Tea Touted Once Again - HealthDay, 10/28/03 - "It's already believed green tea helps lower cholesterol and prevent heart disease, fights bacteria and dental cavities, and possibly helps people lose weight ... Now, two new American studies say it may have anticancer properties, too" - See iHerb or Vitacosticon green tea products.

Ginger Snaps Colon Cancer Growth in Mice - HealthDay, 10/28/03 - "Fifteen days after the cells were injected, the first tumors showed up. Thirteen tumors of a size that could be measured were found in the control mice, but only four were found in the gingerol-treated mice"

Metformin Decreases Serum C-Reactive Protein in Women With Polycystic Ovarian Syndrome - Doctor's Guide, 10/28/03 - "During metformin treatment, serum CRP levels decreased significantly at 6 months overall" -  See metformain at LowPriceMedicine.com.  They have the best price I've seen.  I've ordered metformin from them ($79 for 500 of the 500 mg).  On the down side, it took almost a month to receive it.  It's a prescription drug so check with your doctor.  Related articles:

Scientists concerned about vitamin D levels in the U.S. - USA Today, 10/28/03 - "Heaney cited one study that men needed 1,000 IUs a day during Nebraska winters to keep their vitamin D levels from dropping ... A study of 2,600 healthy Britons given 800 IUs a day saw their risk of bone fractures drop 33%, he said, suggesting today's doses are insufficient to protect bones"

Regular aspirin use linked to pancreatic cancer - USA Today, 10/28/03 - "women who reported 20 or more years of regular aspirin use, with an average intake of at least two or more tablets a week, had a 58% increased risk of pancreatic cancer, compared to those who did not take aspirin. Among those who took 14 tablets or more a week, the risk was 86% greater"

Cholesterol Drugs Offer Hope Against Rheumatoid Arthritis - HealthDay, 10/27/03 - "statins eased some of the inflammation that is a characteristic of rheumatoid arthritis (RA)" - Note:  Red yeast rice is a non-prescription statin but check with your doctor first.  See iHerb, Vitacosticon and  VitaminShoppeicon red yeast rice products.

How to Age Well - WebMD, 10/27/03 - "What made them different than the other half? One thing stands out. Those who stayed healthy had perfectly healthy hearts. They didn't even have "subclinical" heart problems, the ones so minor they can only be detected by testing ... For men, having subclinical heart disease was like being 6.5 years older. For women, it was like being 5.5 years older ... refrain from smoking, lower their blood lipids, watch blood pressure, and avoid obesity through diet and exercise" - [HealthDay]

Bad Cholesterol, Worst Cholesterol - WebMD, 10/27/03 - "Apolipoproteins are tiny fat particles floating in the blood. Having a lot of one kind of Apo -- apolipoprotein B or ApoB -- means high risk of clogged arteries and heart attack ... Most worrisome were study participants with normal LDL but high ApoB. They were more likely to have abdominal obesity, high blood insulin levels, and high levels of clotting factors -- serious risk factors for diabetes and heart disease" - Related articles:

Red Wine Ingredient May Fight COPD - WebMD, 10/27/03 - "resveratrol, a compound found in the skins of red fruits such as grapes, may slow down the inflammatory process involved in the lung disease COPD (chronic obstructive pulmonary disease)"

  • “Grape Expectations”: Lengthen Lifetime with Red Wine? - Physician's Weekly, 9/15/03 - "Resveratrol, a molecule that exists naturally in grapes and red wine, was shown to extend the life span of yeast cells (polyphenols) by up to 80%. The researchers plan to examine resveratrol's effect in multi-cellular organisms such as worms, fruit flies, and eventually humans"

Coke to Launch Cholesterol-Reducing Orange Juice - Yahoo, 10/24/03 - "The product will contain plant sterols, an additive that has been used in cholesterol-fighting margarine and other food products. Plant sterols have been shown to cut bad cholesterol levels by about 10 percent when used consistently ... Consumers would have to drink two 8-ounce servings of Heart Wise per day to get the suggested daily 2 grams of sterols needed to lower cholesterol ... Each serving contains about 110 calories" - Related orange juice article:

  • Men's Health: High Cholesterol Can Save Your Life - ABC News, 11/3/00 - "Drink Orange Juice Everyday ... If you’re built like 25 Canadians at the University of Western Ontario, this will increase your HDL by 21 percent (or 10 to 20 points) within 4 weeks. “We’re not sure, but this effect may be due to a flavonoid in orange juice called hesperidin,” says Elzbieta Kurowska, the study leader"

Obesity: The Little Known Cancer Risk - HealthDay, 10/24/03 - "Being overweight or obese seems to be responsible for 14 percent of all cancer deaths in men and 20 percent of cancer deaths in women"

Younger Adults With Type 2 Diabetes 14 Times More Likely to Suffer Heart Attacks - Doctor's Guide, 10/24/03 - "Young adults, age 18-44, who get type 2 diabetes are 14 times more likely to suffer a heart attack and up to 30 times more likely to have a stroke than their peers without diabetes" - See my diabetes page for diabetes prevention measures.

Lancet Takes Aim at Rosuvastatin in Blistering Editorial - Medscape, 10/23/03 - "More than 80% of patients reach their [low-density lipoprotein cholesterol] goals on the starting dose of 10 mg, which also significantly increases [high-density lipoprotein cholesterol], a profile unmatched by competitor drugs ... Dr Horton added that there is no evidence to support prescribing rosuvastatin over "simvastatin or atorvastatin ... The FDA approved the drug in August at 5-, 10-, and 20-mg doses. An 80-mg dose application was withdrawn by AstraZeneca because of safety concerns about increased risk of rhabdomyolysis, which was the same adverse effect that triggered the withdrawal of Bayer's cerivastatin (Baycol) in 2001. In the Lancet editorial, Dr. Horton wrote that some critics raise similar criticisms about rosuvastatin at the 40-mg dose, which the FDA approved under restricted distribution. He noted in the interview with Medscape that Public Citizen, a U.S. consumer watchdog group affiliated with Ralph Nader, has issued a "Do Not Use" warning about rosuvastatin"

Anaemia in Diabetics Often Unrecognised, Undetected, and Untreated - Doctor's Guide, 10/16/03 - "Although anaemia is a key indicator of renal disease, a significant complication caused by diabetes, most diabetics are not tested for anaemia and remain unaware of an association between anaemia and kidney disease ... reduced quality of life was evident by reports of being down or depressed (21%), very down or depressed (17%), or feeling frustrated (17%)"

Abstracts from this week's Doctor's Guide Nutrition/Dietetics:

Vitamin C improves endothelial function in healthy estrogen-deficient postmenopausal women - Climacteric. 2003 Sep;6(3):238-47 - "These results indicate that endothelial function may be improved acutely by antioxidant treatment in postmenopausal women with established estrogen deficiency"

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