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Recent Longevity News for the seven days ending 3/21/12.  You should consult your doctor if you are taking any medications.

Daydreaming is good for the mind - Fox News, 3/19/12 - "This mind wandering, it seems, actually gives your working memory a workout. Working memory is the mental work space that allows the brain to juggle multiple thoughts simultaneously. The more working memory a person has, the more daydreaming they can do without forgetting the task at hand ... People with overall higher working memory were better able to stay focused when the task at hand required it"

Japanese traditional therapy, honokiol, blocks key protein in inflammatory brain damage, study suggests - Science Daily, 3/19/12 - "honokiol (HNK) is able to down-regulate the production of pro-inflammatory cytokines and inflammatory enzymes in activated microglia via Klf4, a protein known to regulate DNA ... HNK can easily move across the blood brain barrier and we found that HNK reduced levels of pNF-kb and Klf4 as well as the number of activated microglia in the brains of LPS treated mice" - Note:  Relora (honokiol) is also purported to lower cortisol.  See Relora at Amazon.com.

Coffee poses no threat to hearts, may reduce diabetes risk: EPIC data - Nutra USA, 3/19/12 - "There was no link between coffee consumption and the incidence of heart disease, nor the risk of cancer" - [Abstract]

Sun Exposure Not Enough to Correct Vitamin D Deficiency - Medscape, 3/17/12 - "although "sunlight is a very reliable source of vitamin D, nutritional sources are clearly required and are, of course, much safer" - See vitamin D at Amazon.com.

White rice increases diabetes risk, scientists say - Fox News, 3/16/12 - "higher white rice consumption was associated with a significantly elevated risk of Type 2 diabetes. This association seems to be stronger for Asians than for Western populations ... compared with brown rice, white rice has a lower content of many nutrients including fiber, magnesium and vitamins, some of which -- especially fiber and magnesium -- are thought to protect against diabetes" - Note:  It doesn't tell you what the percentage of that increased risk is.

Topical Gel Treats Precancerous Skin Condition - WebMD, 3/15/12 - "Actinic keratoses are typically red, scaly skin lesions that can over time develop into a type of skin cancer. They can often be found on sun-exposed areas of the body such as the face, scalp, arms, and legs ... The new gel, Picato (ingenol mebutate), is applied once daily for two or three days, depending on the area being treated. Other available topical treatments must be used for several weeks, and often irritate the skin. Cryotherapy, or freezing the affected skin area, is also used but can sometimes leave a scar ... Because the new gel is only used for a few days, any irritation is usually short-lived. The short duration also makes people more likely to stay the course ... 42% of people in the first group and 34% of those in the second group who got the new gel showed complete clearance of their lesions" - Note:  I had one of these and I had it frozen and I've now got the scare which is why I'm adding this to my newsletter.

Cell phone use in pregnancy may cause behavioral disorders in offspring - Science Daily, 3/15/12 - "This is the first experimental evidence that fetal exposure to radiofrequency radiation from cellular telephones does in fact affect adult behavior ... They found that the mice that were exposed to radiation tended to be more hyperactive and had reduced memory capacity. Taylor attributed the behavioral changes to an effect during pregnancy on the development of neurons in the prefrontal cortex region of the brain"

PSA Test Cuts Prostate-Cancer Deaths -- At a Cost - WebMD, 3/14/12 - "The odds of dying from prostate cancer are 21% lower 11 years after men are offered routine screening with the controversial PSA blood test ... We more definitively show there is an advantage in screening for prostate cancer, and that the reduction in prostate cancer mortality for those men who are screened amounts to 29%" - Note:  I'm betting they will still be arguing about this in 10 years.

Fatty diets may be associated with reduced semen quality - Science Daily, 3/14/12 - "The study of 99 men in the USA found an association between a high total fat intake and lower total sperm count and concentration. It also found that men who ate more omega-3 polyunsaturated fats (the type of fat often found in fish and plant oils) had better formed sperm than men who ate less ... if men make changes to their diets so as to reduce the amount of saturated fat they eat and increase their omega-3 intake, then this may not only improve their general health, but could improve their reproductive health too ... the relationship between dietary fats and semen quality was largely driven by the consumption of saturated fats. Men consuming the most saturated fats had a 35% lower total sperm count than men eating the least, and a 38% lower sperm concentration" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.

Magnesium lowers blood pressure, study suggests - Science Daily, 3/13/12 - "In the trials, the magnesium supplementation doses ranged from 120 to 973 mg with between 3 to 24 weeks of follow-up. Although not all individual trials showed significance in blood pressure reduction, by combining the trials, the overall data indicated that magnesium supplementation reduced both systolic and diastolic blood pressure. With the best results observed at the higher dosages" - See magnesium supplements at Amazon.com.

False promise - The Daily, 3/13/12 - "Antidepressants help only a small fraction of the people who take them, but that didn’t stop Reuters from running an article that carried the headline: “Study suggests overall benefit from antidepressants.” ... Much of the Reuters article ... contradicts its own headline. It explains that about one in three adults who received a placebo recovered from his or her depression. Only one in five people who popped Prozac recovered from his or her depression because of the chemical’s effects of the drug on the brain. The numbers are even worse for seniors ... To make matters worse, the article only makes a passing mention of the downsides of antidepressants. Effexor can make people nauseous, dizzy, drowsy and even anorexic. Prozac can also cause problems with sleep and digestion"

More trans fat consumption linked to greater aggression, researchers find - Science Daily, 3/13/12 - "The study of nearly 1,000 men and women provides the first evidence linking dTFAs with adverse behaviors that impacted others, ranging from impatience to overt aggression ... We found that greater trans fatty acids were significantly associated with greater aggression, and were more consistently predictive of aggression and irritability, across the measures tested, than the other known aggression predictors that were assessed"

Abstracts from this week's Doctor's Guide Nutrition/Dietetics plus abstracts from my RSS feeds (Click here for the journals, the PubMed ones at the top):

Long-term oral effects in patients treated with radiochemotherapy for head and neck cancer - Support Care Cancer. 2012 Mar 13 - "Eighty-five percent of the patients were classified as suffering from salivary gland hypofunction, as well as 58.2 % considered dryness of the mouth the most debilitating complication ... Considering the late effects assessed, the salivary gland hypofunction was the most significant and received the highest morbidity graduation (grade 2/grade 3); xerostomia was also considered the most debilitating complication after treatment. Data show the role of salivary gland hypofunction in the severity of late mucous membrane complication"

  • Xerostomia - Wikipedia, the free encyclopedia - "Xerostomia ( /ˌzɪərɵˈstoʊmiə/) is the medical term for the subjective complaint of dry mouth due to a lack of saliva. Xerostomia is sometimes colloquially called pasties, cottonmouth, drooth, or doughmouth"

Differential effects of low-dose resveratrol on adiposity and hepatic steatosis in diet-induced obese mice - Br J Nutr. 2012 Mar 14:1-10 - "high-fat diet (HFD) ... daily consumption of a low dose of RV is effective for protecting against diet-induced obesity, hepatic steatosis and dyslipidaemia in HFD-fed mice" - See resveratrol products at Amazon.com.

Prevalence and associated factors of subclinical hypercortisolism in patients with resistant hypertension - J Hypertens. 2012 Mar 7 - "Patients with resistant hypertension had a relatively high prevalence of subclinical hypercortisolism, and its presence is associated with several markers of worse cardiovascular prognosis"

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