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Recent Longevity News for the seven days ending 7/7/10.  You should consult your doctor if you are taking any medications.

Finally, Vitamin E May Work -- And It's in the Liver - Medscape, 7/6/10 - "We used to call this "fatty liver"; now it's got a fancier name -- it's "nonalcoholic steatohepatitis." ... It turned out that only the Vitamin E group managed to reach that level of significance" - See Jarrow FamilE (contains all eight members of the vitamin E family, includes Tocomin) at Amazon.com.

Vitamin D Low in Patients With Headache and Migraine - Medscape, 7/6/10 - "Patients with headache and migraine may need to have their vitamin D levels assessed ... Vitamin D may play some yet unknown role in multiple painful and possibly headache and migraine disorders ... vitamin D is safe when used in physiologic doses of at least 5000 IU/day from all sources, including sunlight, diet, and supplements" - See vitamin D at Amazon.com.

Water's unexpected role in blood pressure control - Science Daily, 7/6/10 - "Name a drink that can make you more alert for late-night studying, prevent you from fainting after giving blood, and even promote a teensy bit of weight loss ... ordinary water -- without any additives -- does more than just quench thirst. It has some other unexpected, physiological effects. It increases the activity of the sympathetic -- fight or flight -- nervous system, which raises alertness, blood pressure and energy expenditure ... We had to unlearn the idea that water had no effect on blood pressure, which is what all medical students had been told until the last couple of years"

Gender gap persists at highest levels of math and science testing, 30-year study finds - Science Daily, 7/6/10 - "boys still outnumber girls by more than about 3-to-1 at extremely high levels of math ability and scientific reasoning"

Cocoa flavanols improve vascular and blood pressure measures for coronary artery disease patients - Science Daily, 7/6/10 - "The findings indicate that foods rich in flavanols -- such as cocoa products, tea, wine, and various fruits and vegetables -- have a cardio-protective benefit for heart disease patients ... The study found a protective effect from a cocoa drink with 375 mg of flavanols, but according to researchers, a standard or recommended dosage has not yet been defined to achieve optimal health benefit ... In the current study, the benefit seen from the two-fold increase in circulating angiogenic cells was similar to that achieved by therapy with statins and with lifestyle changes such as exercise and smoking cessation"

Antioxidants do help arteries stay healthy - Science Daily, 7/5/10 - "Long-term supplementation with dietary antioxidants has beneficial effects on sugar and fat metabolism, blood pressure and arterial flexibility in patients with multiple cardiovascular risk factors ... receive either antioxidants or placebo capsules for six months. Tests at the beginning of the trial, after three months and at the six month mark revealed that the patients in the antioxidant group had more elastic arteries (a measure of increased cardiovascular health) and better blood sugar and cholesterol profiles"

High fructose diet may contribute to high blood pressure, study finds - Science Daily, 7/1/10 - "people who consumed a diet of 74 grams or more per day of fructose (corresponding to 2.5 sugary soft drinks per day) had a 26%, 30%, and 77% higher risk for blood pressure levels of 135/85, 140/90, and 160/100 mmHg, respectively. (A normal blood pressure reading is below 120/80 mmHg.)"

Vitamins B6, B12 May Protect Against Depression in Older Adults - Medscape, 7/1/10 - "Odds of depressive symptoms were 2% lower per year for each additional 10 mg of vitamin B6 and an additional 10 μg of vitamin B12"

Low vitamin D linked to the metabolic syndrome in elderly people - Science Daily, 7/1/10 - "vitamin D inadequacy may be a risk factor for the metabolic syndrome, a condition that affects one in four adults ... Because the metabolic syndrome increases the risk of diabetes and cardiovascular disease, an adequate vitamin D level in the body might be important in the prevention of these diseases ... The researchers found a 48 percent prevalence of vitamin D deficiency" - See vitamin D at Amazon.com.

Increasing fertility threefold with DHEA? - Science Daily, 7/1/10 - "women being treated for infertility who also received supplements of DHEA were three times more likely to conceive than women being treated without the additional drug ... The latter group took 75mg of the supplement daily for 40 days before starting fertility treatments, and continued for up to five months ... In the DHEA group, there was a 23% live birth rate as opposed to a 4% rate in the control group ... More than that, of the pregnancies in the DHEA group, all but one ended in healthy deliveries" - See DHEA at Amazon.com.

Adverse Cardiovascular Events in Older Men Reported in Testosterone Trial, Treatment Phase Halted - Doctor's Guide, 6/30/10 - "found a higher rate of adverse cardiovascular events, such as myocardial infarctions (MIs) and elevated blood pressure, in a group of older men receiving testosterone gel compared with those receiving placebo. Due to these events, the treatment phase of the trial was stopped"

Key mechanism links virgin olive oil to protection against breast cancer - Science Daily, 6/30/10 - "virgin olive oil is associated with higher incidences of benign breast tumours and at the same time with a decrease in the activity of the p21Ras oncogene, which spurs uncontrolled cell proliferation and stimulates the growth of tumours. In addition, olive oil suppresses the activity of some proteins, such as the AKT, essential for the survival of cells since they prevent apoptosis, the cell's "suicide" programme. Between proliferation and apoptosis in tumour cells, these effects tip the balance towards cell death, thereby slowing the growth of tumours" - See olive leaf extract at Amazon.com.

Virgin olive oil and a Mediterranean diet fight heart disease by changing how our genes function - Science Daily, 6/30/10 - "The first group consumed a traditional Mediterranean diet with virgin olive oil rich in polyphenols. The second group consumed a traditional Mediterranean diet with an olive oil low in polyphenols. The third group followed their habitual diet. After three months, the first group had a down-regulation in the expression of atherosclerosis-related genes in their peripheral blood mononuclear cells. Additionally, the olive oil polyphenols made a significant impact on the expression of genetic changes influencing coronary heart disease. Results also showed that the consumption of virgin olive oil in conjunction with a Mediterranean diet can positively impact lipid and DNA oxidation, insulin resistance, inflammation, carcinogenesis, and tumor suppression ... olive oil and a Mediterranean diet affect our bodies in a far more significant way than previously believed" - See olive leaf extract at Amazon.com.

Olympic gold? A new effect of caffeine boosts performance - Science Daily, 6/29/10 - "high doses of caffeine directly increase muscle power and endurance during relatively low-intensity activities ... a caffeine dosage of 70 µM enhanced power output by ~6% during both types of activity. This effect in humans is likely to be very similar"

Abstracts from this week's Doctor's Guide Nutrition/Dietetics plus abstracts from my RSS feeds (Click here for the journals, the PubMed ones at the top):

Green Tea Supplementation Affects Body Weight, Lipids, and Lipid Peroxidation in Obese Subjects with Metabolic Syndrome - J Am Coll Nutr. 2010 Feb;29(1):31-40 - "Green tea beverage consumption (4 cups/d) or extract supplementation (2 capsules/d) for 8 weeks significantly decreased body weight and BMI. Green tea beverage further lowered lipid peroxidation versus age- and gender-matched controls, suggesting the role of green tea flavonoids in improving features of metabolic syndrome in obese patients" - See green tea extract at Amazon.com.

Effect of Omega-3 Fatty Acids Supplementation on Depressive Symptoms and on Health-Related Quality of Life in the Treatment of Elderly Women with Depression: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial - J Am Coll Nutr. 2010 Feb;29(1):55-64 - "Supplementation with n-3 LCPUFA is efficacious in the amelioration of depressive symptoms and quality of life in the treatment of depressed elderly female patients" - See Mega Twin EPA at Amazon.com and Jarrow Max DHA at Amazon.com.

S-Adenosyl Methionine (SAMe) Augmentation of Serotonin Reuptake Inhibitors for Antidepressant Nonresponders With Major Depressive Disorder: A Double-Blind, Randomized Clinical Trial - Am J Psychiatry. 2010 Jul 1 - "These preliminary results suggest that SAMe can be an effective, well-tolerated, and safe adjunctive treatment strategy for SRI nonresponders with major depressive disorder and warrant replication" - See SAM-e at Amazon.com.

Neat Tech Stuff / "How To's" (formatting FAT32 with Windows Vista):

  • Many components such as karaoke players, Blu-ray players, PlayStation3, etc. require hard drives or flash memories formatted for FAT32 however Windows Vista won't allow you to format a hard drive or hard drive partition greater than 32 GB.  You can go with a flash but if you have an old hard drive that too small for today's back-up (like with video back-ups) you can make those hard drives work.  Some sites say just use the DOS command "format /FS:FAT32 x:" were "x" is the drive but that doesn't work  with my Vista SP2. Click here for the procedure.

Health Focus (Olive Leaf):

Specific Recommendations:

News and Research:

  • Key mechanism links virgin olive oil to protection against breast cancer - Science Daily, 6/30/10 - "virgin olive oil is associated with higher incidences of benign breast tumours and at the same time with a decrease in the activity of the p21Ras oncogene, which spurs uncontrolled cell proliferation and stimulates the growth of tumours. In addition, olive oil suppresses the activity of some proteins, such as the AKT, essential for the survival of cells since they prevent apoptosis, the cell's "suicide" programme. Between proliferation and apoptosis in tumour cells, these effects tip the balance towards cell death, thereby slowing the growth of tumours" - See olive leaf extract at Amazon.com.
  • Virgin olive oil and a Mediterranean diet fight heart disease by changing how our genes function - Science Daily, 6/30/10 - "The first group consumed a traditional Mediterranean diet with virgin olive oil rich in polyphenols. The second group consumed a traditional Mediterranean diet with an olive oil low in polyphenols. The third group followed their habitual diet. After three months, the first group had a down-regulation in the expression of atherosclerosis-related genes in their peripheral blood mononuclear cells. Additionally, the olive oil polyphenols made a significant impact on the expression of genetic changes influencing coronary heart disease. Results also showed that the consumption of virgin olive oil in conjunction with a Mediterranean diet can positively impact lipid and DNA oxidation, insulin resistance, inflammation, carcinogenesis, and tumor suppression ... olive oil and a Mediterranean diet affect our bodies in a far more significant way than previously believed"
  • Olive-oil enriched diet helps breast cancer survivors lose more weight - Science Daily, 6/3/10
  • Olive oil component could avert Alzheimer’s - Nutra USA, 10/20/09 - "ADDLs bind within the neural synapses of the brains of Alzheimer's patients and are believed to directly disrupt nerve cell function, eventually leading to memory loss, cell death and global disruption of brain function ... incubation with oleocanthal changed the structure of ADDLs by increasing the protein's size" - [Abstract]
  • Natural Compound In Extra-virgin Olive Oil -- Oleocanthal -- May Help Prevent, Treat Alzheimer's - Science Daily, 9/29/09 - "Measuring ADDL binding with and without oleocanthal, they discovered that small amounts of oleocanthal effectively reduced binding of ADDLs to hippocampal synapses. Additional studies revealed that oleocanthal can protect synapses from structural damage caused by ADDLs ... An unexpected finding was that oleocanthal makes ADDLs into stronger targets for antibodies. This action establishes an opportunity for creating more effective immunotherapy treatments, which use antibodies to bind to and attack ADDLs"
  • Source Of Major Health Benefits In Olive Oil Revealed - Science Daily, 4/1/09 - "Scientists have pinned down the constituent of olive oil that gives greatest protection from heart attack and stroke. In a study of the major antioxidants in olive oil, Portuguese researchers showed that one, DHPEA-EDA, protects red blood cells from damage more than any other part of olive oil"
  • Extra Virgin Olive Oil May Help To Combat Breast Cancer - Science Daily, 2/5/09 - "this study confirms the potentiality of polyphenols to inhibit HER2 activity and to promote its degradation"
  • New Anti-cancer Components Of Extra-virgin Olive Oil Revealed - Science Daily, 12/17/08 - "Extra-virgin olive oil is the oil that results from pressing olives without the use of heat or chemical treatments. It contains phytochemicals that are otherwise lost in the refining process. Menendez and colleagues separated the oil into fractions and tested these against breast cancer cells in lab experiments. All the fractions containing the major extra-virgin phytochemical polyphenols (lignans and secoiridoids) were found to effectively inhibit HER2"
  • Olive Leaf Extract Can Help Tackle High Blood Pressure And Cholesterol - Science Daily, 8/27/08 - "This works showed that taking a 1000mg dose has substantial effects in people with borderline hypertension"

Abstracts:

No pathinfo

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