Recent Longevity News for the seven days ending 3/18/09.  You should consult your doctor if you are taking any medications.

Scientists Discover Why A Low GI Meal Makes You Feel Full - Science Daily, 3/18/09 - "Eating a meal with a low GI (glycaemic index) increases gut hormone production which leads to suppression of appetite and the feeling of fullness"

Cholinesterase Inhibition Combined With Antioxidants May Help Alzheimer's Disease Outcomes - Doctor's Guide, 3/17/09 - "Addition of a defined antioxidants formulation (Formula F) to donepezil treatment of patients with mild Alzheimer's disease (AD) substantially reduces oxidative stress and provides significant benefits over treatment with donepezil alone"

Not Enough Vitamin D In The Diet Could Mean Too Much Fat On Adolescents - Science Daily, 3/16/09 - "A Medical College of Georgia study of more than 650 teens age 14-19 has found that those who reported higher vitamin D intakes had lower overall body fat and lower amounts of the fat in the abdomen, a type of fat known as visceral fat, which has been associated with health risks such as heart disease, stroke, diabetes and hypertension" - See vitamin D at Amazon.com.

Quercetin Inhibits Path to Myocardial Ischemia-Reperfusion Injury - Medscape, 3/16/09 - "The naturally occurring flavone quercetin inhibits mRNA and protein expression of several components involved in the pathophysiology of myocardial ischemia-reperfusion injury in rabbits"

Low Creatinine Levels Linked to Diabetes - Medscape, 3/13/09 - "The multiple-adjusted odds ratio for those who had serum creatinine between 0.40 and 0.60 mg/dL was 1.91 compared with those who had levels between 0.71 and 0.80 mg/dL"

High IQ Linked To Reduced Risk Of Death - Science Daily, 3/13/09 - "a lower IQ was strongly associated with a higher risk of death from causes such as accidents, coronary heart disease and suicide ... the link between IQ and mortality could be partially attributed to the healthier behaviours displayed by those who score higher on IQ tests ... People with higher IQ test scores tend to be less likely to smoke or drink alcohol heavily, they eat better diets, and they are more physically active"

Air Pollution Dangerous, but Deadly? - WebMD, 3/11/09 - "the risk of dying from respiratory problems is more than 30% greater in metropolitan areas with the highest ozone concentrations than areas where ozone levels were the lowest ... ozone at ground level is produced when exhaust from cars, power plants, and other sources reacts chemically in sunlight ... ground-level ozone can irritate breathing, decrease lung function, inflame airways, and worsen lung conditions such as asthma and emphysema" - SUV's!!!

Consuming A Little Less Salt Could Mean Fewer Deaths - Science Daily, 3/11/09 - "A 3-gram–a-day reduction in salt intake (about 1200 mg of sodium) would result in 6 percent fewer cases of new heart disease, 8 percent fewer heart attacks, and 3 percent fewer deaths ... Currently, Americans eat 9-12 grams of salt per day"

Consuming A Little Less Salt Could Mean Fewer Deaths - Science Daily, 3/11/09 - "Participants who slept on average less than six hours a night during the work week, when followed over six years, were 4.56 times more likely than those getting six to eight hours of sleep to convert from normal blood sugar levels to impaired fasting glucose"

Neck Size Linked to Heart Risk - WebMD, 3/11/09 - "the bigger a person's neck size, the greater that person's risk of high levels of LDL "bad" cholesterol and blood fat, insulin resistance, and high blood sugar"

Low Vitamin D Hurts Teenagers’ Hearts - WebMD, 3/11/09 - "Compared to the 25% of teens with the highest levels of vitamin D in their blood (more than 26 nanograms per milliliter), the 25% of teens with the lowest vitamin D levels (less than 15 ng/mL) had: ... Fourfold greater risk of metabolic syndrome, a combination of risk factors for diabetes ... 2.54 times greater risk of high blood sugar ... 2.36 times greater risk of high blood pressure" - See vitamin D at Amazon.com.

Abstracts from this week's Doctor's Guide Nutrition/Dietetics plus abstracts from my RSS feeds (Click here for the journals, the PubMed ones at the top):

Resveratrol inhibits the expression of SREBP1 in cell model of steatosis via Sirt1-FOXO1 signaling pathway - Biochem Biophys Res Commun. 2009 Mar 13;380(3):644-9 - "Our results suggest that resveratrol may attenuate fat deposition by inhibiting SREBP1 expression via Sirt1-FOXO1 pathway and thus may have application for the treatment of NAFLD" - See resveratrol products at Amazon.com.

Does valerian improve sleepiness and symptom severity in people with restless legs syndrome? - Altern Ther Health Med. 2009 Mar-Apr;15(2):22-8 - "The results of this study suggest that the use of 800 mg of valerian for 8 weeks improves symptoms of RLS and decreases daytime sleepiness in patients that report an Epworth Sleepiness Scale (ESS) score of 10 or greater. Valerian may be an alternative treatment for the symptom management ofRLS with positive health outcomes and improved quality of life" - See valerian root at Amazon.com.

Neat Tech Stuff :

http://web.archive.org/collections/web.html has saved my butt several times.  This time I reinstalled Windows Vista and went to the website to get the software to decrypted .tivo files to .mpg.  The web site is no longer there but I had the URL and pasted it into the archive website and was able to download the "Direct Show Dump Untility" that I needed.  If you ever plan on getting TiVo you might want to go to http://web.archive.org/web/20080103132425/http://www.prish.com/etivo/tbr.htm and get Direct Show Dump now.

Health Focus (Osteoporosis):

Popular Medications:

• Actonel (risedronate) / Boniva (ibandronate) / Didronel (etidronate) / Evista (raloxifene) / Forteo (teriparatide) / Fortical / Fosamax (alendronate) / Reclast (zoledronic acid) / HRT

Popular Supplements:

• calcium / magnesium / vitamin D / vitamin K / soy isoflavones / red clover / omega-3 / vitamin C / silicon

Alternative News:

• Osteoporosis - Life Extension Foundation
• Osteoporosis - HealthGate
• 19 Key Bone Building Nutrients Chart - betterbones.com
• Spinal Vertebral Fractures - susanbrownphd.com
• Moderate Alcohol Intake Associated With Bone Protection - Science Daily, 3/3/09 - "In an epidemiological study of men and post-menopausal women primarily over 60 years of age, regular moderate alcohol intake was associated with greater bone mineral density (BMD). Researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (USDA HNRCA) at Tufts University found associations were strongest for beer and wine and, importantly, BMD was significantly lower in men drinking more than two servings of liquor per day"
• Building Strong Bones: Running May Provide More Benefits Than Resistance Training, Study Finds - Science Daily, 2/27/09 - "both resistance training and high-impact endurance activities increase bone mineral density. However, high-impact sports, like running, appear to have a greater beneficial effect"
• Flaxseed combined with low-dose estrogen therapy preserves bone tissue in ovariectomized rats - Menopause. 2009 Jan 29 - "Flaxseed + low-dose estrogen therapy resulted in the highest bone mineral density and peak load at the lumbar vertebrae, with no effect on bone mineral density or strength in the tibia and femur. Flaxseed and flaxseed + low-dose estrogen therapy resulted in significantly higher relative levels of alpha-linolenic acid and eicosapentaenoic acid and lower levels of linoleic acid, arachidonic acid, and n-6/n-3 ratio in the lumbar vertebrae and tibia compared with all other groups" - See flax seed at Amazon.com.
• Nutrient Supports Bone Health Over Time - Science Daily, 1/20/09 - "The results suggest there is a protective effect of carotenoids, particularly of lycopene, against bone loss in older adults. The researchers concluded that carotenoids may explain, in part, the previously observed protective effects of fruit and vegetable consumption on bone mineral density" - See Jarrow Lyco-Sorb (contains Lyco-O-Mato) at Amazon.com.
• Genistein Safely Improves Bone Formation in Osteopenic, Postmenopausal Women - Medscape, 1/14/09 - "Usually, the drugs used in the management of osteopenia/osteoporosis have been classified as predominantly 'antiresorptive agents' or as 'bone-forming agents' but, on the basis of our results, genistein might represent the first therapy that overcomes this classification by combining a powerful bone-forming as well as an antiresorptive activity ... All postmenopausal women with bone loss would be ideal candidates for genistein aglycone treatment ... Genistein aglycone has a good safety profile, and in addition it is effective against climacteric syndrome (i.e., hot flushes and night sweats)"
• Calcium And Vitamin D May Not Be The Only Protection Against Bone Loss - Science Daily, 12/3/08 - "Diets that are high in protein and cereal grains produce an excess of acid in the body which may increase calcium excretion and weaken bones ... When fruits and vegetables are metabolized they add bicarbonate, an alkaline compound, to the body ... bicarbonate had a favorable effect on bone resorption and calcium excretion ... 171 men and women aged 50 and older were randomized to receive placebo or doses of either: potassium bicarbonate, sodium bicarbonate, or potassium chloride for three months. Researchers found that subjects taking bicarbonate had significant reductions in calcium excretion, signaling a decrease in bone resorption"
• Tea Drinking May Help Preserve Hip Structure in Elderly Women - Medscape, 10/29/08 - "The cross-sectional analysis revealed that mean total hip aBMD was 2.8% greater in tea drinkers ... Compared with non–tea drinkers, tea drinkers had a significantly higher aBMD at the total hip and trochanter sites but not at the femoral neck and intertrochanter sites" - See green tea extract at Amazon.com.
• Vitamin C linked to Reduced Bone Loss in Older Men - WebMD, 9/19/08 - "If you don't have enough vitamin C, you don't make bones right. Collagen is the principal protein of bones, accounting for nearly half the volume. What the collagen does is prevent bones from coming apart" - See vitamin C products at Amazon.com.
• Calcium With or Without Vitamin D May Help Prevent Osteoporosis - Medscape, 8/27/08 - "For best therapeutic effect, we recommend minimum doses of 1200 mg of calcium, and 800 IU of vitamin D (for combined calcium plus vitamin D supplementation)"
• Vitamin K good for young bones, too: study - Nutra USA, 7/17/08 - "These findings suggest that improvement in vitamin K status, and thus in the amount of active osteocalcin, might significantly improve bone health in children, even in those with arthritis" - See vitamin K at Amazon.com.
• Calcium Alone Does Not Reduce Hip Fracture Risk - Science Daily, 6/29/08 - "a recent analysis of several studies found no reduction in risk of hip fracture with calcium supplementation ... Future studies of fracture prevention should focus on the best combination of calcium plus vitamin D, rather than on calcium supplementation alone"
• Choline-stabilized orthosilicic acid supplementation as an adjunct to Calcium/Vitamin D3 stimulates markers of bone formation in osteopenic females: a randomized, placebo-controlled trial - BMC Musculoskelet Disord. 2008 Jun 11;9(1):85 - "There were no ch-OSA related adverse events observed and biochemical safety parameters remained within the normal range ... Combined therapy of ch-OSA and Ca/Vit D3 had a potential beneficial effect on bone collagen compared to Ca/Vit D3 alone which suggests that this treatment is of potential use in osteoporosis" - See Jarrow BioSil at Amazon.com.  I take about 9 drops per day of it with my orange juice.
• Vitamin D status and response to treatment in post-menopausal osteoporosis - Osteoporos Int. 2008 Jun 13 - "The adjusted odds ratio for incident fractures in vitamin D deficient as compared to vitamin D repleted women was 1.77 ... Optimal vitamin D repletion seems to be necessary to maximize the response to anti-resorbers in terms of both BMD changes and anti-fracture efficacy" - See vitamin D at Amazon.com.
• Current Vitamin D Recommendations Fraction Of Safe, Perhaps Essential Levels For Children - Science Daily, 5/27/08 - "The current recommended daily allowance (RDA) of vitamin D for children is 200 International Units (IUs), but new research reveals that children may need and can safely take ten-times that amount ... Only children given the equivalent of 2,000 IUs a day of vitamin D increased 25-OHD levels from the mid-teens to the mid-thirties (ng/ml)--the level considered optimal for adults. None of the children in either trial showed any evidence for vitamin D intoxication"  - Seevitamin D at Amazon.com.  I've gone to the vitamin D 2000 IU at Amazon.com.  If you're worried about that being to high, just skip a day or two per week which most do anyway just by forgetting to take them.
• Relationship of sex steroid hormones with bone mineral density in a nationally-representative sample of men - Clin Endocrinol (Oxf). 2008 May 14 - "Men in the lowest quartile of free estradiol had 70% increased odds (OR=1.69, 95% CI 0.95-2.98) of osteopenia compared with men in the highest quartile. Men in the lowest quartile of free testosterone had nearly four times the odds of osteopenia than those in the highest quartile (OR=3.82; 95% CI 1.87-7.78). Lower concentrations of SHBG appeared protective against osteopenia (p-trend=0.01). Neither total testosterone nor total estradiol was associated with BMD, although men with clinically low estradiol (<20 ng/l) had lower BMD (0.930 g/cm(2), 95% CI 0.88-0.98) than men with normal-range estradiol (1.024 g/cm(2), 1.01-1.04; p=0.004"
• Aggressive Vitamin D Treatment for Osteoporosis - Medscape, 5/19/08 - "Singh called the findings "alarming" and said that although many physicians believe vitamin D deficiency is not a problem, with 41% of study patients found to have a vitamin D level of less than 30 ng/mL, "most likely that is not true," he said" - See vitamin D at Amazon.com.
• Vitamin D, calcium combo may cut exercise-related stress fractures - Nutra USA, 4/25/08 - "randomly assigned the recruits to receive daily supplements of 2,000 mg of calcium and 800 IU of vitamin D, and the other group received a placebo ... Women receiving the vitamin-mineral combination were 20 per cent less likely to experience the fractures" - [Abstract]
• Calcium and vitamin d supplementation decreases incidence of stress fractures in female navy recruits - J Bone Miner Res. 2008 May;23(5):741-9 - "randomized them to 2000 mg calcium and 800 IU vitamin D/d or placebo ... found a 21% lower incidence of fractures in the supplemented versus the control group" - [Nutra USA]
• Effects of conjugated linoleic acid and exercise on bone mass in young male Balb/C mice - Lipids Health Dis. 2006 Mar 23;5:7 - "Conjugated Linoleic Acid (CLA) has been reported to lower body fat mass. However, weight loss is generally associated with negative effects on bone mass, but CLA is reported to have beneficial effects on bone ... a combination therapy of CLA and EX on bone health has not been studied ... although CLA decreased gain in body weight by 35%, it however increased bone mass by both reducing bone resorption and increasing bone formation. EX also decreased gain in body weight by 21% and increased bone mass; but a combination of CLA and EX, however, did not show any further increase in bone mass" - See conjugated linoleic acid at Amazon.com.
• Better Bone Density Test - Dr. Weil, 1/14/08 - "If you’re a woman at risk for osteoporosis, I strongly recommend that you have a DEXA scan ... In addition, I recommend that all women supplement with 500 to 700 mg of calcium citrate in two divided doses taken with meals ... For men, I now suggest aiming for 500 mg from all sources. (Because higher amounts have been linked to increased risks of prostate cancer, men generally should avoid supplemental calcium.) I also recommend that both men and women take 1,000 IU of vitamin D3"
• Effect of dehydroepiandrosterone supplementation on bone mineral density, bone markers, and body composition in older adults: the DAWN trial - Osteoporos Int. 2007 Dec 15 - "Among older healthy adults, daily administration of 50 mg of DHEA has a modest and selective beneficial effect on BMD and bone resorption in women, but provides no bone benefit for men"
• Soy isoflavone intake increases bone mineral density in the spine of menopausal women: Meta-analysis of randomized controlled trials - Clin Nutr. 2007 Dec 4 - "Isoflavone intervention significantly attenuates bone loss of the spine in menopausal women. These favorable effects become more significant when more than 90mg/day of isoflavones are consumed. And soy isoflavone consumption for 6 months can be enough to exert beneficial effects on bone in menopausal women"
• Optimal vitamin d status for the prevention and treatment of osteoporosis - Drugs Aging. 2007;24(12):1017-29 - "Vitamin D deficiency [as defined by a serum 25(OH)D level of <50 nmol/L (<20 ng/mL)] is pandemic. This deficiency is very prevalent in osteoporotic patients. Vitamin D deficiency causes osteopenia, osteoporosis and osteomalacia, increasing the risk of fracture. Unlike osteoporosis, which is a painless disease, osteomalacia causes aching bone pain that is often misdiagnosed as fibromyalgia or chronic pain syndrome or is simply dismissed as depression. Vitamin D deficiency causes muscle weakness, increasing the risk of falls and fractures, and should be aggressively treated with pharmacological doses of vitamin D. Vitamin D sufficiency can be sustained by sensible sun exposure or ingesting at least 800-1000IU of vitamin D(3) daily" - See vitamin D at Amazon.com.
• Tea drinking is associated with benefits on bone density in older women - Am J Clin Nutr. 2007 Oct;86(4):1243-1247 - "In the cross-sectional analysis, total hip aBMD was 2.8% greater in tea drinkers (x: 806; 95% CI: 797, 815 mg/cm(2)) than in non-tea drinkers (784; 764, 803 mg/cm(2)) (P < 0.05). In the prospective analysis over 4 y, tea drinkers lost an average of 1.6% of their total hip aBMD (-32; -45, -19 mg/cm(2)), but non-tea drinkers lost 4.0%" - See green tea extract at Amazon.com.
• Drinking Tea May Slow Bone Loss - WebMD, 10/8/07 - "A new study shows elderly women who drank tea had higher bone density in their hips and less bone loss than women who didn't drink tea ... Previous studies have suggested that phytochemicals in tea, such as flavonoids, may be responsible for the protective effect against bone loss due to their estrogen-like properties"
• New Proof of Genistein's Efficacy and Safety for Osteopenia and Osteoporosis Published in Annals of Internal Medicine - Doctor's Guide, 7/16/07 - "85% of the women taking genistein showed a gain in bone density ... In addition, women taking genistein with calcium and vitamin D achieved a gain in bone density of approximately 3% per year over baseline and 6% per year over those taking the placebo"
• Soy Compound May Bolster Women's Bones - WebMD, 6/18/07 - "After two years, the DEXA scans showed increases in bone mineral density in women taking genistein"
• Two-year randomized controlled trial of vitamin K1 (phylloquinone) and vitamin D3 plus calcium on the bone health of older women - J Bone Miner Res. 2007 Apr;22(4):509-19 - "women who took combined vitamin K and vitamin D plus calcium showed a significant and sustained increase in both BMD and BMC at the site of the ultradistal radius"
• Not just calcium and vitamin d: other nutritional considerations in osteoporosis - Curr Rheumatol Rep. 2007 Feb;9(1):85-92 - "Other nutritional considerations include nutrients such as vitamin B-12 and vitamin K that may reduce fracture risk by increasing bone mineral density as well as the improvement of bone microarchitecture. Diets high in fruits and vegetables contribute nutrients such as magnesium associated with bone health and may also produce an alkaline environment, reducing calcium excretion and thus improving bone density"
• Soy isoflavone intake inhibits bone resorption and stimulates bone formation in menopausal women: meta-analysis of randomized controlled trials - Eur J Clin Nutr. 2007 Mar 28 - "Isoflavone intervention significantly inhibits bone resorption and stimulates bone formation"
• n-3 Fatty acids are positively associated with peak bone mineral density and bone accrual in healthy men: the NO2 Study - Am J Clin Nutr. 2007 Mar;85(3):803-7 - "The results showed that n-3 fatty acids, especially DHA, are positively associated with bone mineral accrual and, thus, with peak BMD in young men" - See Mega Twin EPA at Amazon.com or Jarrow Max DHA at Amazon.com.
• Vitamin K(2) supplementation improves hip bone geometry and bone strength indices in postmenopausal women - Osteoporos Int. 2007 Feb 8 - "Vitamin K(2) helps maintaining bone strength at the site of the femoral neck in postmenopausal women by improving BMC and FNW, whereas it has little effect on DXA-BMD" - See vitamin K at Amazon.com.
• Beware of Bone Boosters? - Dr. Weil, 2/8/07 - "I also worry about using bisphosphonates on a long-term basis because of new evidence showing that they can lead to very serious problems. Dentists have been observing that some patients on these drugs are at risk of developing an untreatable condition called osteonecrosis of the jaw (ONJ). Osteonecrosis means death of bone tissue. ONJ can cause chronic pain and disfigurement. Symptoms include toothache, jaw pain, loosening of teeth, recurrent infection of the soft tissue of the jaw, and exposed bone"
• Vitamin link to bone loss probed - BBC News, 11/14/06 - "Increased amounts of homocysteine in the blood may increase the risk of developing osteoporosis ... Individuals who have a poor dietary intake of B-vitamins tend to have high homocysteine levels"
• Potassium citrate supplements linked to thicker bones - Nutra USA, 10/12/06 - "Taking potassium citrate supplements could boost bone mineral density by similar amounts as observed with pharmaceuticals ... At the end of the study, women taking the potassium citrate supplement are reported to have a significant, one per cent increase in BMD in the vertebrae of the lower back (lumbar spine), compared to baseline ... However, the bone mineral density of the lumbar spine of women taking the potassium chloride supplement (none alkaline) was found to have significantly decreased after one year of supplementation, by about one per cent" - See iHerb or Vitacost potassium citrate products.
• CLA continues to offer possibilities for bone health - Nutra USA, 10/2/06 - "After 10 weeks of either diet, it was found that the CLA-fed mice had higher bone mineral density (BMD) in specific bone regions than corn oil (CO)-fed mice. This increased BMD was tied to a reduced activity of pro-inflammatory cytokines (such as tumor necrosis factor alpha (TNF-alpha), and interleukin-6 (IL-6)) ... the CLA-fed mice also had significantly lower fat mass and increased muscle mass, compared to CO-fed mice" - See CLA products at iHerb or Vitacost.
• Study Suggests Vitamin K Deficiency as an Osteoporosis Risk Factor - Doctor's Guide, 9/22/06 - "one of the early effects of declining estrogen is the impairment of vitamin K function in bone even before any bone loss that could be attributed to menopause can be measured ... Our study suggests that the generally accepted level of vitamin K in healthy women is inadequate to maintain bone health just at the onset of menopause" - See iHerb or Vitacost vitamin K products.
• Soy Isoflavones Protect Postmenopausal Women From Bone Loss - Medscape, 7/14/06 - "There was a significant, linear dose-related response for isoflavones vs placebo in terms of bone density at the lumbar spine and femoral neck, but not at the trochanter"
• Strong support for vitamin K’s bone health benefits - Nutra USA, 6/27/06 - "Supplementation of vitamin K (MK-4) resulted in reductions in hip fractures of 77 per cent, vertebral fracture of 60 per cent, and all non-vertebral fractures of 81 per cent"
• Increasing Dietary and Supplemental Calcium - Medscape, 6/16/06 - "Postmenopausal women, as reported in many studies, tend to have average serum 25(OH)D values ranging from 50 to 55 nmol/L (20 to 22 ng/mL)[8,10] and are therefore absorbing the calcium they ingest with reduced efficiency ... raising serum 25(OH)D from the typical postmenopausal range up to 75 nmol/L resulted in a 33% reduction in all osteoporotic fractures combined"
• Soy isoflavones attenuate bone loss in early postmenopausal Chinese women : A single-blind randomized, placebo-controlled trial - Eur J Nutr. 2006 Jun 8 - "There is a significantly dose-dependent effect of soy isoflavones on attenuating bone loss at the spine and femoral neck possibly via the inhibition of bone resorption in non-obese postmenopausal Chinese women with high Kuppermann Scale"
• Evaluating vitamin D status. Implications for preventing and managing osteoporosis and other chronic diseases - Joint Bone Spine. 2006 Feb 17 - "recent review articles indicate that current reference ranges for serum 25-OH-vitamin D are too low. An appropriate lower normal limit may be between 50-100 nmol/l (20-40 ng/ml). Standard supplement dosages may fail to provide concentrations above this range" - See iHerb or Vitacost vitamin D products.
• Vitamin K treatment for postmenopausal osteoporosis in Indonesia - J Obstet Gynaecol Res. 2006 Apr;32(2):230-4 - "After 48 weeks of treatment, the mean percentage change of lumbar BMD in the vitamin K(2) group was significantly higher (P < 0.05) than that of the control group" - See iHerb or Vitacost vitamin K products.
• Women with Osteoporosis May Need More Vitamin D - Healthwell, 3/16/06 - "More than half of American women receiving drug therapy for osteoporosis are deficient in vitamin D ... The new research suggests that many women with osteoporosis are using drugs to treat a problem that could be helped simply by getting sun more often or by taking a nutritional supplement"
• Bone care: It's still basic - USA Today, 3/5/06 - "the postmenopausal women in the study weren't typical. Most who were assigned to take supplements also got lots of calcium and vitamin D in their diets, so adding pills didn't make much difference. And many who were assigned placebos also took supplements on their own, something researchers allowed ... It's not surprising there was a blunted response ... The National Osteoporosis Foundation saw nothing in the study to change its endorsement of calcium and vitamin D"
• Calcium Plus Vitamin-D Supplementation Does An Older Body Good - Science Daily, 2/24/06 - "The older the woman, the more likely it is that consistent use of calcium and vitamin-D supplements will play a role in reducing her risk for osteoporosis"
• Study Finds Calcium Supplements Don't Prevent Broken Bones - New York Times, 2/15/06 - "the participants were randomly assigned to take 1000 milligrams of calcium and 400 international units of vitamin D a day ... When they looked only at the women who took 80 percent of their pills, the supplements reduced hip fractures by 29 percent. The annual rate of hip fractures in adherent women taking the supplements was 10 per 10,000, compared with 14 per 10,000 in adherent women taking placebos"
• Calcium, Vitamin D: Help Women's Hips? - WebMD, 2/15/06 - "Calcium and vitamin D supplements may help protect some older women's hips -- but only when taken regularly"
• Magnesium Prevents Osteoporosis - Healthwell, 2/9/06 - "a higher magnesium intake was associated with greater whole-body bone mineral density, after adjusting for calcium and vitamin D intake, level of exercise, use of estrogen medication, and other factors known to be related to bone health"
• Strategies for Preventing Osteoporosis in Men - Life Extension Magazine, 1/06 - "For men, maintaining good bone health starts with regular doctor visits to screen for bone mineral density and prostate cancer. Other essentials are regular, weight-bearing exercise, healthy, moderate-protein diets, and supplements including vitamin D, calcium, magnesium, and isoflavones to help prevent bone mineral losses"
• Dietary Magnesium Could Lead to Stronger Bones - Doctor's Guide, 12/21/05 - "For every 100 milligram per day increase in magnesium intake, data showed a 1% increase in bone density ... this link was only true for the older white men and women" - See iHerb or Vitacost magnesium products.
• Magnesium could reduce osteoporosis risk - Nutra USA, 12/8/05 - "Higher Mg intake through diet and supplements was positively associated with total-body [bone mineral density] BMD in older white men and women. For every 100 mg per day increase in Mg, there was an approximate 2 per cent increase in whole-body BMD"
• Nutritional Interventions in Osteoporosis - Medscape, 12/1/05 - "For adults over 50 years of age, the DASH diet emphasizing fruit and vegetables as well as dairy products and whole grains and beans, together with a calcium and a vitamin D supplement, will provide dietary defense against osteoporosis"
• Silicon may boost calcium/vitamin D bone benefits - Nutra USA, 11/23/05 - "Jarrow Formulas ... The effect was particularly pronounced in the PINP, the most sensitive bone formation marker. In the groups receiving six and 12mg of silicon, the improvements were “significant”" - See Jarrow BioSil at iHerb.
• Leading Osteoporosis Experts Reach Consensus on Role of Vitamin D in Bone Health in Americans Over 50 - Doctor's Guide, 11/22/05 - "over 70% of women ages 51-70 and nearly 90% of women over 70 are not getting the recommended adequate intake of vitamin D ... The roundtable panelists expressed concern that current recommendations do not provide for optimal bone health and recommended that intake levels be increased to 800-1,000 IU per day for patients over age 50" - See iHerb or Vitacost vitamin D products.
• Adequate Vitamin D Status Appears More Important than High Calcium Intake for Maintaining Calcium Metabolism - Doctor's Guide, 11/8/05 - "vitamin D sufficiency may be more important than high calcium intake in maintaining desired values of serum PTH ... Vitamin D supplements are necessary to ensure adequate vitamin D status for most of the year in northern climates" -  See iHerb or Vitacost vitamin D products.
• Most Postmenopausal Women Are Vitamin D Deficient - Doctor's Guide, 9/29/05 - "64% of postmenopausal women with osteoporosis have a vitamin D deficiency" -  See iHerb or Vitacost vitamin D products.
• Prevalence of Vitamin D Inadequacy Among Postmenopausal North American Women Receiving Osteoporosis Therapy - Obstet Gynecol Surv. 2005 Oct;60(10):658-659 - "An adequate intake of vitamin D and calcium is viewed as a necessary part of treating osteoporosis ... At a cutoff point of 30 ng/mL, the prevalence of inadequacy was 63% in women taking less than 400 IU daily and 45% in those taking 400 IU or more" -  See iHerb or Vitacost vitamin D products.
• Potassium, The Hidden Bone Guardian - betterbones.com, 9/29/05
• Women Need More Calcium, Say Experts - WebMD, 9/28/05
• Postmenopausal Women Falling Far Short of Calcium Goals: Presented at ASBMR - Doctor's Guide, 9/28/05 - "A study finds that 85% of postmenopausal women do not consume enough calcium every day, and on average consume about 500 mg less than the US government's recommended daily intake (RDA)"
• Silicon May Play Important Role in Bone Health - Doctor's Guide, 9/27/05 - "Silicon, taken as choline-stabilized orthosilicic acid (ch-OSA) supplementation, might help improve bone health and type I collagen synthesis ... the benefits were especially apparent when evaluating changes in PINP, the most sensitive bone formation marker, and resulted in significant improvements after 12 months amongst the subjects in the six and 12 mg silicon groups" - See Jarrow BioSil at iHerb.
• After Menopause: Eating Soy May Help Bones - WebMD, 9/12/05 - "Within 10 years of menopause, the 20% who ate the most soy foods reported half as many fractures as the 20% who ate the least soy ... The highest level of consumption among Chinese women was about 13 grams of soy protein a day. A cup of soy milk contains about 6.6 grams"
• Taking A Break From Fractures: A Closer Look At Vitamin D - Science Daily, 8/11/05 - "The researchers concluded, though, that higher daily doses, in the range of 700 to 800 IU, may reduce the risk of fracture by approximately 25 percent ... only subjects receiving higher doses of vitamin D supplementation had significantly fewer fractures than did subjects in the comparison groups" - See iHerb or Vitacost vitamin D products.
• Balance of Essential Fats May Prevent Bone Loss After Menopause - Doctor's Guide, 7/13/05 - "After 12 weeks, rats with the lowest ratio of omega-6 to omega-3 fatty acids in their diet experienced significantly less bone loss than rats in the other dietary groups ... A 5-to-1 dietary ratio of omega-6 to omega-3 fatty acids led to a conservation of bone mineral content that we didn't see with a 10-to-1 ratio" -  See Mega Twin EPA at Amazon.com or Vitacost.
• Omega-3, Omega-6 Fatty Acids Can Affect Bone Loss - CBS 2 Chicago, 7/12/05 - "eating foods rich in omega-3 fatty acids -- found in walnuts and salmon -- may prevent bone thinning. While excess amounts of omega-6 -- found in grains and beef -- may actually promote bone loss ... a low ratio of omega-6 to omega-3 appears to be best"
• Vitamin D Deficit: Women's Silent Bone Threat - WebMD, 5/20/05 - "The study included 1,554 postmenopausal U.S. women being treated for osteoporosis ... More than half of the women (52%) had less-than-optimal levels of vitamin D ... Doctors need to pay more attention to vitamin D status"
• Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials - JAMA. 2005 May 11;293(18):2257-64 - "Oral vitamin D supplementation between 700 to 800 IU/d appears to reduce the risk of hip and any nonvertebral fractures in ambulatory or institutionalized elderly persons. An oral vitamin D dose of 400 IU/d is not sufficient for fracture prevention"
• Homocysteine and vitamin b(12) status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people - J Bone Miner Res. 2005 Jun;20(6):921-9 - "High Hcy and low vitamin B(12) concentrations were significantly associated with low BUA, high markers of bone turnover, and increased fracture risk"
• Osteoporosis: the role of micronutrients - Am J Clin Nutr. 2005 May;81(5):1232S-9S - "Calcium has been shown to have beneficial effects on bone mass at all ages, although the results are not always consistent. Higher doses than the current US recommendation (600 IU) of vitamin D in the elderly (age >/= 65 y) may actually be required for optimal bone health (800-1000 IU/d) ... The other micronutrient needs for optimizing bone health can be easily met by a healthy diet that is high in fruits and vegetables to ensure adequate intakes for magnesium, potassium, vitamin C, vitamin K, and other potentially important nutrients"
• Fight Osteoporosis: Bone Up On B12 - Science Daily, 4/23/05 - "This study suggests adequate vitamin B12 intake is important for maintaining bone mineral density"
• Folate and Vitamin B12 Prevent Hip Fracture in Stroke Patients - Medscape, 3/25/05 - "The magnitude of benefit is similar to that found in trials of alendronate and raloxifene, with considerably less potential risk. The fact that BMD did not change suggests the benefit derives from quality, rather than quantity, of bone"
• Onions May Fight Osteoporosis - WebMD, 4/8/05
• Aerobic Exercise, Weights Boost Bone Strength - WebMD, 4/4/05
• Calcium Supplements: Benefits and Risks - Medscape, 1/26/05 - "Perhaps the most effective method of preventing osteoporosis is ingestion of adequate calcium. Experts suggest the daily requirement for calcium is 1,300 mg for people ages 9 to 18, 1,000 to 1,200 mg for adults 19 to 50, and 1,500 mg for people over 50 ... You should take only the amount of calcium recommended. Ingesting high doses of calcium each day can be harmful and can cause kidney stones"
• Got Fruit? Bones Need More Than Milk - WebMD, 10/26/04 - "Most people eat a diet that generates acids ... This increase in acid levels is thought to reduce bone strength ... Eating foods that buffer the acidic foods builds strong bones ... Nutrients found in fruits and vegetables may be protective for bone health ... The teenage girls who ate a large amount of fruit had the strongest bones"
• Study Says What's Good for the Heart May Be Good for the Bones - Doctor's Guide, 10/7/04 - "The study demonstrated a gain of up to 5% in bone mineral density (BMD) at the hip in postmenopausal women who drank 2 or fewer glasses of wine daily, and up to 7% in men who drank 1 or 2 beers daily"
• Vitamin K, bone turnover, and bone mass in girls - Am J Clin Nutr. 2004 Oct;80(4):1075-80 - "Better vitamin K status was associated with decreased bone turnover in healthy girls consuming a typical US diet"
• Vitamin D Inadequacy Highly Prevalent Among Women Treated for Osteoporosis in North America - Doctor's Guide, 10/4/04 - "More than half of women currently treated for osteoporosis have suboptimal levels of vitamin D"
• Got Exercise? Workouts Better for Bone Health - WebMD, 6/11/04
• Vitamins May Lower Osteoporosis Fractures - Intelihealth, 5/13/04 - "B vitamins are known to reduce levels of homocysteine ... high levels of homocysteine at least double the risk of osteoporosis-related fractures"
• High protein promotes bone health - Nutra USA, 4/5/04
• Low B-12 Levels Linked to Increased Rate of Bone Loss - Medscape, 3/19/04 - "The results of this study raise the possibility that supplementation with vitamin B-12 or, for some elderly women, dietary assessment and modification may slow rates of bone loss" - See iHerb or Vitacost Vitamin B12 products.
• Vitamin B12 levels linked to bone loss - Nutra USA, 3/4/04 - "after adjusting for age, weight and clinic site, women with the lowest levels of B12 (below 280 pg/ml) experienced significantly more rapid hip bone loss than women with higher levels of B12"
• Best Ways To Fight Osteoporosis - CBS News, 9/18/03 - "64 percent of women don't know how much calcium they need every day ... women from 19- to 50-years-old should consume 1,000 mg; and women over 50-years-old should consume 1,200 mg ... a high calcium intake will not protect a person against bone loss caused by estrogen deficiency, physical inactivity, smoking, alcohol abuse or various medical disorders or treatments" - See drugstore.com/GNC calcium products.
• Vitamin D Supplementation and Fracture Prevention - Medscape, 9/11/03 - "Bottom line: Vitamin D supplementation is absolutely critical to bone health in the aging population. Although a number of research questions still need to be addressed, there is currently sufficient evidence to show that all women, living in areas of Northern Latitude, should be taking a vitamin D (and calcium) supplement"
• 60-Minute Workout Stops Bone Loss - WebMD, 9/5/03 - "Postmenopausal women who work out for 60 minutes, three times a week -- and take calcium -- can stop bone loss ... calcium alone isn't enough -- you also need vitamin D"
• Exercise Prevents Bone Loss in Early Post-Menopausal Women - New Hope Natural Media, 8/14/03
• Vitamin D and Calcium Supplementation Effective for Prevention and Treatment of Osteoporosis - Doctor's Guide, 7/18/03 - "Adequate vitamin D and calcium intake is essential to the prevention and treatment of osteoporosis. The Institute of Medicine (IOM) recommends 200 IU/day of vitamin D for women aged 50 or younger years, 400 IU/day for those aged 51-70 years, and 600 IU/day for those older than 70 years ... In women over the age of 65, there is increased risk of osteoporotic fracture of the hip and non-vertebral sites. Daily vitamin D intake between 800 and 900 IU and 1200-1300 mg of calcium for this population results in increased bone density, decreased bone turnover, and decreased non-vertebral fractures ... Studies have linked vitamin D supplementation to a decrease in body sway, suggesting that vitamin D supplementation may protect against fracture by preventing falls" - See drugstore.com/GNC calcium plus vitamin D supplements.
• Effects on bone mineral density of calcium and vitamin D supplementation in elderly women with vitamin D deficiency - Joint Bone Spine. 2003 Jun;70(3):203-208 - "bone mass in older women with vitamin D deficiency increases significantly at the lumbar spine, femur, trochanter, and whole body after calcium and vitamin D supplementation for 1 year, and concomitantly bone markers improved as vitamin D levels returned to normal"
• Protein intake: effects on bone mineral density and the rate of bone loss in elderly women - Am J Clin Nutr. 2003 Jun;77(6):1517-25 - "The highest quartile of protein intake (: 72 g/d) was associated with higher BMD in elderly women at baseline only when the calcium intake exceeded 408 mg/d"
• Calcium Supplementation and Exercise Improves Bone Mineral Status in Adolescent Girls - Doctor's Guide, 4/10/03
• Vitamin D Plus Calcium Supplements Boosts Calcium Absorption - WebMD, 4/1/03 - "We need calcium for good bones, but vitamin D is equally important -- it helps the body with calcium absorption. In fact, calcium supplements plus vitamin D can increase calcium absorption by up to 65%"
• Vitamin K Builds Strong Bones - New Hope Natural Media, 3/28/03 - "Without adequate vitamin K, osteocalcin cannot be produced, and bone formation becomes impaired ... when women with osteoporosis take supplemental vitamin K, the urinary excretion of calcium falls by about 50%, suggesting that less calcium is being leached from the bones ... Some research, however, suggests that the optimal level of intake may be higher, as much as 400 mcg per day. A typical western diet contains 80 to 150 mcg per day" - See iHerb or Vitacost vitamin K products.
• Remember Sodium? We're Still Getting Too Much - Intelihealth, 3/14/03 - "High sodium levels also raise the risk of osteoporosis and kidney problems ... In the case of osteoporosis, potassium appears to offset calcium losses from excessive sodium ... postmenopausal women with diets high in salt lost higher amounts of bone mineral. Eating potassium-rich foods such as bananas, tomatoes and orange juice helped stem the calcium loss"
• Interaction of Dietary Calcium and Protein in Bone Health in Humans - J. Nutr. 133:852S-854S, 3/03 - "Protein has both positive and negative effects on calcium balance, and the net effect of dietary protein on bone mass and fracture risk may be dependent on the dietary calcium intake. In addition to providing substrate for bone matrix, dietary protein stimulates the production of insulin-like growth factor-1 (IGF-1), a factor that promotes osteoblast-mediated bone formation. Protein also increases urinary calcium losses, by several proposed mechanisms. Increasing calcium intake may offset the negative impact of dietary protein on urinary calcium losses, allowing the favorable effect of protein on the IGF-1 axis to dominate"
• Vitamin D Can Prevent Fractures In Older People - Intelihealth, 2/28/03
• Vitamin D Helps Elderly Avoid Fractures - WebMD, 2/27/03
• Calcium, vitamin D, milk consumption, and hip fractures: a prospective study among postmenopausal women - Am J Clin Nutr. 2003 Feb;77(2):504-11 - "Women consuming 12.5 µg vitamin D/d from food plus supplements had a 37% lower risk of hip fracture (RR = 0.63; 95% CI: 0.42, 0.94) than did women consuming < 3.5 µg/d. Total calcium intake was not associated with hip fracture risk (RR = 0.96; 95% CI: 0.68, 1.34 for 1200 compared with < 600 mg/d). Milk consumption was also not associated with a lower risk of hip fracture (P for trend = 0.21)"
• Vitamin K intake and bone mineral density in women and men - Am J Clin Nutr. 2003 Feb;77(2):512-6 - "Low dietary vitamin K intake was associated with low BMD in women ... In contrast, there was no association between dietary vitamin K intake and BMD in men"
• Walking Your Way to Better Bones - WebMD, 11/13/02
• Low Vitamin D Levels Not Restricted To High-risk Groups - Doctor's Guide, 9/23/02 - "Vitamin D insufficiency is far more common than is generally assumed and is not necessarily restricted to high-risk groups such as the elderly ... Low vitamin D levels were found across diagnostic categories and were identified in 88 percent of patients with hip fractures; 67 percent of patients with wrist fractures; 50 percent of patients with vertebral fractures, and 52 percent of patients with other fractures ... This study demonstrates the high frequency of hypovitaminosis D in a UK specialist bone clinic setting and the clear need for vitamin D therapy may not [be] appreciated without [taking] vitamin D measurements"
• Low Bone Mineral Density and Quantitative Ultrasound in Men Associated with Low Vitamin K Status - Doctor's Guide, 9/23/02 - "Low vitamin K status is associated with low quantitative ultrasound (QUS) and low bone mineral density (BMD) of the femoral neck and trochanter ... What we did was measure the amount of vitamin K in circulation and use the more sensitive measures of vitamin K status which was % undercarboxylated osteocalcin ... We corrected for triglycerides because vitamin K is transported in the blood by triglyceride-rich lipoproteins ... What we found was that the higher the amounts of vitamin K in the plasma, the higher the BMD" - So does that mean that if your triglycerides are in check you may need extra vitamin K?  See iHerb and Vitacost vitamin K products. - Ben
• Treating & Preventing Osteoporosis - Life Extension Magazine, 9/02 - "From systematic research the best external evidence is available for a supplementation with calcium and vitamin D and a therapy with the bisphosphonates alendronate or risedronate, as well as the selective estrogen receptor modulator raloxifene (Evista)."
• People Living In Higher Latitudes Require Fall, Winter Vitamin D Supplements - Doctor's Guide, 6/10/02 - "Given that almost every person in our sample had serum 25-hydroxyvitamin D [25(OH)D] levels below 80 nmol/L at one point in the year, and that more than one-third of subjects had levels below the most conservative definition of vitamin D insufficiency, our findings support a recommendation for more aggressive vitamin D supplementation, particularly for elderly people and especially during the fall and winter months ... Low levels of vitamin D metabolites are associated with malabsorption of calcium, which results in bone loss"
• Soy Isoflavone May Improve Bone Metabolism in Perimenopausal Women - Doctor's Guide, 5/27/02 - "The isoflavone group (n=12) received daily capsules of soy isoflavone extract (61.8 mg of isoflavones) ... Excretion of bone resorption markers was reduced significantly in the isoflavone group"
• Getting Calcium On Young Girls' Radar - Intelihealth, 5/23/02 - "Ninety percent of girls ages 9 to 12 don't get enough calcium in their diets ... Ninety to 98 percent of your skeletal system is developed by age 20, so it's important that these bone-healthy activities are done early. After that, you're either going to maintain the bone density or you're going to lose it"
• Long-Time Tea Drinking Builds Strong Bones - WebMD, 5/14/02
• Calcium and Vitamin D3 Effective and Cost-Saving in Preventing Hip Fracture in Elderly European Women - Doctor's Guide, 5/13/02 - "simple dietary supplementation with calcium and vitamin D not only helps prevent hip fracture in institutionalized elderly women, it also saves up to 711,000 Euros (some US $640,000) per 1000 treated ... One group received elemental 1200 mg/day calcium plus 800 IU/day vitamin D3, while the other received a placebo. After three years, 25 percent fewer hip fractures were found among members of the supplemented group ... The savings may even be greater than this: remember, this study only takes into account hip fractures, but supplementation could prevent many other types of fracture as well"
• Tea May Strengthen Bones - Intelihealth, 5/13/02
• Aging Bone Mineral Density Better With High Protein Diet Plus Extra Calcium, Vitamin D - WebMD, 4/1/02
• High-Protein Diet Could Repair Bone Loss - WebMD, 3/25/02 - "The supplement group -- particularly those who ate a diet high in protein -- had significantly better bone mass density -- an accurate measure of bone loss. Those who took the placebo, however, had less calcium absorbed into their bloodstream when they consumed more protein"
• Does High Intake of Vitamin A Pose a Risk for Osteoporotic Fracture? - JAMA. 2002 Mar 20;287(11):1396-7 - "the evidence relating to a possible relationship between moderately high retinol intake and possible adverse effects on bone health remains inconclusive"
• Curbing Caffeine May Benefit Bones - HealthandAge, 1/11/02
• Kids Plagued by 'Calcium Crisis' - WebMD, 12/14/01 - "Only 14% of girls and 36% of boys age 12 to 19 in the U.S. are getting the recommended amounts of calcium, according to the U.S. Department of Agriculture ... Close to 90% of adult bone is established by the end of the teen years. So if kids are off to a bad start in getting enough calcium, says the National Institute of Child Health and Human Development (NICHD), down the road, they are at serious risk of developing the brittle-bone disease osteoporosis as well as other bone diseases"
• Calcium, Keep What You Take - Life Extension Magazine, 3/99
• Vitamin K Deficiency Linked to Low Bone Mineral Density in Women - Doctor's Guide, 10/15/01
• Vitamin K Cuts Hip Fractures - Nutrition Science News, 9/01
• Vitamin E May Help Prevent Menopause Bone Loss - WebMD, 6/28/01 - "Treating these rats with vitamin E at a dose comparable to 400 IU in humans was just as good as estrogen treatment in restoring bone density and weight"
• Study Relates Jogging And Strong Bones - Intelihealth, 6/28/01 - "Young men who jog regularly build strong bones and may be less likely to develop the brittle bone disease osteoporosis ... For couch potatoes, men who do little or no exercise, the bone density of joggers was almost 8 percent better"
• Not for Ladies Only: Soy May Also Help Men at Risk for Osteoporosis - WebMD, 4/2/01 - "research suggests that a diet enriched with soy protein, which some research has shown can help preserve women's bones, may be able to do the same thing for men ... The group consuming soy protein had significantly more of this growth factor"
• PUFAs (omega-3 polyunsaturated fatty acids) for Bone Growth and Repair - Nutrition Science News, 3/01
• Vitamin C May Help Ward Off Osteoporosis - WebMD, 2/8/01 - "Researchers have found that postmenopausal women who took vitamin C supplements had a higher bone density than those who didn't. The highest bone densities were also found in the women who were taking more than 1,000 mg/d."
• High Impact Physical Activity Cuts Hip-Fracture Risk - Doctor's Guide, 1/18/01
• Bone Up on Osteoporosis - Nutrition Science News, 11/00
• Calcium Less Available from Soy Milk - Nutrition Science News, 10/00
• Supplemental Calcium Can Limit Early On-Set Of Osteoporosis In Children With Asthma - Doctor's Guide, 10/16/00
• Bone Up on Calcium Supplements, What Are Their Benefits and Risks? - WebMD, 9/19/00
• Soy Isoflavones Reduce Bone Loss In Perimenopausal Women - Doctor's Guide, 9/1/00
• Good Nutrition Important for Prevention of Osteoporosis - WebMD, 5/19/00
• There's Something to Be Said for Having 'Tea Bones' - WebMD, 4/14/00
• Researchers Suggest Daily Tea May Fortify Bones Of Elderly Women - Intelihealth, 4/7/00
• Hearts & Bones: Calcium's Many Applications - Nutrition Science News, 2/00
• The Replacements - Nutrition Science News, 8/99
• Postmenopausal Bone Loss Prevented With Low Dose HRT Plus Calcium - Doctor's Guide, 6/2/99
• Osteoporosis: You can prevent it - CNN, 6/2/99
• Can ipriflavone prevent osteoporosis? - Nutrition Science News, 5/99
• Anti-dairy group opens campaign attacking benefits of milk - CNN, 3/1/99
• Calcium supplementation prevents seasonal bone loss and changes in biochemical markers of bone turnover in elderly New England women: a randomized placebo-controlled trial - J Clin Endocrinol Metab 1998 Nov;83(11):3817-25
• Weight training, calcium, hormones the key to fighting osteoporosis - CNN, 11/6/98
• Low Dietary Calcium, Low Vitamin C Linked To Increased Risk Of Gum Disease - Doctor's Guide, 6/29/98
• Female Teens Need Calcium During Window Of Opportunity - Doctor's Guide, 9/5/97
• Report: Americans need more calcium - CNN, 8/13/97

Other News:

• Popular Class Of Diabetes Drugs Doubles Risk Of Fractures In Women - Science Daily, 12/10/08 - "We knew going into this study that there was an association between thiazolidinediones and fracture risk ... these agents double the risk of fractures in women with type 2 diabetes"
• Adiponectin Is A Metabolic Link Between Obesity And Bone Mineral Density - Science Daily, 11/25/08 - "adiponectin, a protein secreted from adipocytes, is a metabolic link that can explain, in part, the known positive relationship between obesity and both bone mineral density and reduced susceptibility to fractures ... In summary, elevated circulating adiponectin was associated with lower bone mass and weaker bones in growing mice compared to control animals" - See my adiponectin page for ways to increase it. - Ben
• Angiotensin II type 2 receptor blockade increases bone mass - J Biol Chem. 2008 Nov 11 - "Treatment with AT2 receptor blocker significantly enhanced the levels of bone mass and this effect was based on the enhancement of osteoblastic activity as well as the suppression of osteoclastic activity in vivo" - That might be another good reason for telmisartan as a first line treatment for hypertension.  See telmisartan at OffshoreRx1.com.
• Too Much Body Fat Bad for Bones? - WebMD, 10/31/08 - "postmenopausal women with a higher proportion of body fat tend to have lower bone mineral content"
• Guidelines for Osteoporosis Treatment - WebMD, 9/15/08
• New Test for Osteoporosis Fracture Risk - WebMD, 6/24/08
• Testosterone Replacement Theraphy Beneficial In Men 60 And Older, Study Suggests - Science Daily, 4/7/08 - "These preliminary data show beneficial effects of testosterone therapy on bone turnover markers in older men with low-to-normal testosterone concentrations using both continuous and monthly cycled testosterone replacement"
• Low Testosterone Levels Associated With Risk Of Fracture In Men Over 60 - Science Daily, 1/14/08 - "Although low levels of estradiol and testosterone were associated with a higher risk of fracture in men over 60, only the effect of testosterone was independent of other risk factors, the authors conclude"
• Chocolate consumption and bone density in older women - Am J Clin Nutr. 2008 Jan;87(1):175-80 - "Higher frequency of chocolate consumption was linearly related to lower bone density and strength (P < 0.05). Daily (>/=1 times/d) consumption of chocolate, in comparison to <1 time/wk, was associated with a 3.1% lower whole-body bone density; with similarly lower bone density of the total hip, femoral neck, tibia, and heel; and with lower bone strength in the tibia and the heel"
• Many Osteoporosis Medications Prevent Fractures, but None Is Proven Best - Doctor's Guide, 12/18/07
• Depression Associated With Low Bone Mineral Density - Medscape, 12/3/07 - "The novelty of this study is the fact that these women were not severely depressed ... Depression is considered a disease of chronic stress, Dr. Cizza said, with attendant increases in the stress hormone cortisol, and cytokines produced by the immune system. "Those substances are helpful to fight stress, but if there is too much cortisol or cytokines, there are side effects," he said. "One of the side effects is bone loss, so it was obvious to ask the question, 'do women with depression have low bone mass?'""
• New Diabetes Drugs Bad for Bones - WebMD, 12/3/07 - "The diabetes drug Avandia promotes osteoporosis not only by slowing bone growth but also by speeding up bone loss. Actos, the only other drug in the same class, likely does this as well"
• Depression Linked To Bone-thinning In Premenopausal Women - Science Daily, 11/26/07 - "The researchers found that 17 percent of the depressed women had thinner bone in a vulnerable part of the hip called the femoral neck, compared with 2 percent of those who were not depressed"
• Just Being Naturally Thin May Raise Risk of Osteoporosis in Women - Doctor's Guide, 11/8/07
• The association of sex hormone levels with quantitative ultrasound, bone mineral density, bone turnover and osteoporotic fractures in older men and women - Clin Endocrinol (Oxf). 2007 Jun 6 - "oestradiol (E2) and testosterone (T) ... Low levels of bioE2 and bioT were found to be associated with high bone turnover, low QUS and BMD and high risk of osteoporotic fractures in both men and women"
• Antidepressant Use May Boost Fracture Risk - Science Daily, 5/29/07 - "people ages 50 and over who regularly took antidepressants called selective serotonin reuptake inhibitors (SSRIs) had double the rate of fractures as people not using such medications"
• Once-a-year Drug Reduces Fractures From Osteoporosis - Doctor's Guide, 5/4/07
• Relation of Cortisol Levels and Bone Mineral Density Among Premenopausal Women With Major Depression - Medscape, 5/4/07 - "a lower BMD and increased bone resorption were found in women with mild depression. Major depression had important effects on BMD and bone turnover markers. Depression should be considered among risk factors for osteoporosis in premenopausal women, therefore it may be useful to assess BMD values of MDD patients, and to treat them in cases of lower BMD values"
• Men Warned Of Osteoporosis Problems - Science Daily, 1/31/07 - "Statistically, one in three men die following a fracture, compared to one in five women, possibly because of underlying health problems such as heart disease which make it difficult for them to cope with a fracture that could involve hip surgery, prolonged bed rest and rehabilitation"
• Study Says Depression May Weaken Bones - WebMD, 10/30/06 - "After four weeks, the depressed mice had lost bone density, the study shows. The problem: They had a drop in bone-building cells called osteoblasts ... When the depressed mice drank water laced with imipramine, their depression eased and their bone loss stopped"
• Study Links Cola to Bone Loss in Women - WebMD, 10/6/06 - "drinking cola soft drinks on a regular basis was associated with lower bone mineral density in the hip"
• Low Bone Density May Predict Cognitive Impairment - Doctor's Guide, 5/5/06 - "Low bone mineral density (BMD) in postmenopausal women may be associated with cognitive impairment, and estrogen metabolism may be the cause"
• Elderly Men Who Fall Should Be Screened for Osteoporosis - Doctor's Guide, 5/5/06
• Low Estrogen May Up Men’s Hip Fracture - WebMD, 5/3/06
• Lack of Estrogen Linked to Hip Fractures in Men - Intelihealth, 5/1/06 - "men who have lost bone mass should take calcium and vitamin D supplements to help reverse bone loss and reduce the risk of hip fractures ... This is an interesting paper and tends to confirm that among men, estradiol (estrogen) levels may be more important to bone strength than is testosterone"
• FDA Approves Once-a-Week Osteoporosis Hormone Therapy Patch Climara Pro (Estradiol/Levonorgestrel) - Doctor's Guide, 1/4/06 - "the FDA has approved the hormone therapy patch, Climara Pro® (estradiol/levonorgestrel transdermal system), for the prevention of postmenopausal osteoporosis"
• Women Over 50 Likely to Have Both Low Bone Mineral Density and Elevated Cholesterol - Doctor's Guide, 10/4/05 - "17.3 million (43%) of women over 50 years had osteopenia, and 4.8 million (12%) had osteoporosis, while 18.2 million (45%) had normal BMD"
• Treating Osteoporosis: What Works Best? - WebMD, 8/10/05 - "Treatment with parathyroid hormone increases bone density. But women who took parathyroid hormone for a year progressively lost bone density afterward unless they took Fosamax"
• What's Best for Bones? - Dr. Weil, 5/13/05
• Bone Fracture Rates Significantly Reduced Over Just Two Years in Patients Who Consistently Stayed on Bisphosphonate Therapy for Osteoporosis - Doctor's Guide, 4/7/05 - "We found that women with postmenopausal osteoporosis who faithfully continued to take their prescribed bisphosphonate medication reduced their risk for fractures substantially more - about 25% - than women who did not"
• Newer Antiepileptics May Increase Risk of Osteoporosis - Clinical Psychiatry News, 4/05
• Few Patients Exposed to High-Dose Corticosteroids Receive Osteoporosis Education - Doctor's Guide, 3/28/05
• More Osteoporosis Seen With Raw Foods Diet - WebMD, 3/28/05
• Osteoporosis and Bone Health - Physician's Weekly, 3/21/05 - "half of all Americans older than 50 will be at risk for fractures from osteoporosis and low bone mass by 2020 if no immediate actions are taken ... Calcium and vitamin D intakes are far below recommended levels for all ages, sexes, and races in the United States"
• Dental X-Rays Could Be First Step in Osteoporosis Screening - Doctor's Guide, 12/1/04
• Osteoporosis Drugs May Prevent Knee Arthritis - WebMD, 11/4/04
• Four Osteoporosis Drugs Show No Difference in Impact on Endothelial Function - Doctor's Guide, 10/11/04
• Ultra-Low Dose Estradiol Good for Bone Health, and Appears to Have No Impact on Endometrium - Doctor's Guide, 10/11/04 - "14 mcg of estradiol patch ... By the end of 2 years, there was a 2.6% increase in bone mineral density of the lumbar spine over baseline, and a 0.4% increase in BMD at the hip. By comparison in the placebo group, the increase in BMD of the spine was 0.6% and there was a loss in BMD at the hip of 0.8% ... These ultra-low doses of estradiol should be sufficient to preserve bone health in women over the age of 60 years"
• Declining Estradiol Levels More Predictive of Fracture Risk Than Low Testosterone in Aging Men - Doctor's Guide, 10/8/04 - "While low levels of free testosterone are a predictor of hip-bone loss, declines in estradiol levels play a stronger role than testosterone"
• Exercise More Critical Than Calcium For Adolescent Bones - Doctor's Guide, 6/9/04 - "Exercise is more influential than calcium intake in determining bone strength in young women ... attaining optimal bone mass and bone strength in adolescence may offer the best protection possible against osteoporosis - bone loss in post-menopausal women and the elderly"
• New Fracture Risk: High Homocysteine - WebMD, 5/12/04
• Postmenopausal Women Show Significantly Reduced Incident Fracture Risk While on Hormone Therapy - Doctor's Guide, 5/12/04 - "We found a significantly reduced risk of fracture a year or so after women had started using hormone therapy, with the risk decreasing further with increasing duration of use"
• Ultra-Low Dose Estrogen Patch Helps Bones - WebMD, 5/4/04
• Ultra-Low-Dose Estradiol Patch Stops Bone Turnover, Increases Bone Density - Medscape, 5/4/04 - "The patch dose is "roughly one fourth of the standard 0.625-mg dose usually prescribed for menopause symptoms ... That minimal increase translated into a "3% increase in BMD at the spine compared to placebo and a 1.5% increase at the hip compared to placebo ... All women received 800 mg calcium and 400 IU vitamin D daily"
• Peak Bone Mass, Size Appear Almost Fully Attained by Late Adolescence - Doctor's Guide, 4/6/04
• Few Treated for Osteoporosis; Many at Risk - WebMD, 3/26/04 - "Researchers say recent advances in the prevention and treatment of osteoporosis not only slow the bone-thinning disease, but they can also help rebuild your bones ... The problem is, only a fraction of those at risk for the disease are ever screened for osteoporosis"
• Inhaled Steroids: More Evidence of Bone Loss - WebMD, 3/26/04
• Inverse Relationship Observed Between Statin Treatment and Risk of Hip Fracture - Doctor's Guide, 3/12/04 - "The risk of hip fracture decreased as the number of statin prescriptions increased ... 0.72 ... for subjects who redeemed more than 3 statin prescriptions"
• Statins May Help Prevent Bone Fractures - WebMD, 1/26/04 - "statin users had a 38%-81% lower risk of hip bone fractures and a 5%-51% lower risk of nonspinal fractures ... statin use was associated with a 57% reduction in the number of hip fractures reported and a 31% reduction in nonspinal fractures"
• Human Parathyroid Hormone Appears Effective, Safe in Increasing Bone Mineral Density in Postmenopausal Osteoporosis - Doctor's Guide, 11/20/03
• Is Low Bone Mass in Men an Underdiagnosed Disease State? - Doctor's Guide, 10/31/03 - "The leading three risk factors from the questionnaire for predicting bone loss were history of smoking, no calcium supplementation, and difficulty maintaining an erection ... 62.5% showed evidence of either osteopenia (> -1.0 SD of bone mass density [BMD]) or osteoporosis"
• More Awareness of Guidelines to Prevent Corticosteroid-Induced Osteoporosis - Medscape, 10/27/03
• Few Get Osteoporosis Drugs After Falls - WebMD, 10/2/03 - "only 22% of elderly men and women who had a major bone fracture filled a prescription for an osteoporosis drug within six months after their injury ... that's despite the fact that people who have suffered one fracture from osteoporosis are up to five times more likely so suffer another one, and use of osteoporosis drugs can reduce that risk of by as much as 60%"
• Statins Used to Treat High Cholesterol and Osteoporosis - Doctor's Guide, 9/30/03 - "simvastatin acts as a double therapeutic weapon by blocking the conversion of HMG-CoA to mevalonate. Not only does this action increase new bone formation via the stimulation of osteoblasts, but it also prevents the production of cholesterol"
• Men Present With More Severe Osteoporosis Than Women - Medscape, 9/25/03
• Most Postmenopausal Women With Fractures Not Prescribed Osteoporosis Medications - Doctor's Guide, 9/26/03
• Postmenopausal Women with Fracture are Under-Treated - Doctor's Guide, 9/24/03 - "The majority of postmenopausal women with low trauma fracture are not being treated with osteoporosis medications"
• Regular Cola Consumption Linked to Lower Bone Density in Women - Medscape, 9/22/03 - "Among the female subjects, regular cola drinkers had decreased BMD compared with the infrequent drinkers. BMD was 2.3% lower in the trochanter, 3.3% lower in the femoral neck, and 5.1% lower in Ward's area ... When phosphoric acid comes packaged with other nutrients, it's absorbed normally and everything is in balance. We think the problem with cola is that you're getting those doses of phosphoric acid without any calcium. It's not balanced, and that extra phosphorus binds with calcium and prevents it from being absorbed"
• Cessation of Hormone Replacement Results in Rapid Increase in Bone Turnover, Bone Loss - Doctor's Guide, 9/2/03 - "HRT withdrawal was followed by significant bone loss, with an annual rate ranging from -0.7 to -1.6% ... These findings have important implications for women who are given HRT for preventing the risk of osteoporosis"
• Peak Bone Mineral Density Has Greatest Influence on Onset of Osteoporosis - Doctor's Guide, 8/27/03
• Low-Dose Oestrogen Increased Bone Density in Older Women Without Increasing Oestrogen-Associated Adverse Effects - Doctor's Guide, 8/26/03 - "They randomised 167 women, older than 65 years of age, to receive either 0.25 mg/day micronized 17beta-estradiol or placebo for 3 years ... patients treated with low-dose estradiol showed bone mineral density increases of 2.6% at the femoral neck, 3.6% of the total hip, 2.8% at the spine, and 1.2% in total body measurements. Similar bone mineral density changes were seen between those who received and did not receive progesterone"
• Male Master Cyclists at Potential High-Risk for Developing Osteoporosis - Doctor's Guide, 7/24/03 - "Of the master cyclists, 15% met the World Health Organisation's criteria for having osteoporosis and 52% for having osteopaenia at either the spine or hip or both. This compares to 0% of the non-athletes who met the criteria for osteoporosis and 42% who met the criteria for osteopaenia ... The authors recommend that cyclists supplement their training with weight-bearing exercise, receive periodic BMD screening, and include adequate levels of dietary calcium and vitamin D" - See OS-Cal Plus at drugstore.com.
• Osteoporosis Linked to Joint Destruction in Postmenopausal Rheumatoid Arthritis - Doctor's Guide, 7/21/03 - "Up to 56% of postmenopausal women with rheumatoid arthritis (RA) who are not treated with hormone replacement therapy (HRT) or bisphosphonates develop osteoporosis"
• Low Bone Mineral Density Is Associated With Future Dementia - Clinical Psychiatry News, 7/03
• Menopausal Estrogen-Related Bone Loss Much Greater than Age-Related Bone Loss - Doctor's Guide, 6/25/03 - "In middle-aged women, age-related bone loss has a minor impact on the metabolic activity of bone compared to the impact of estrogen loss that accompanies menopause, which affects metabolic activity and bone density to a larger degree"
• Too Much or Too Little Vitamin A Raises Hip-Fracture Risk in Post-Menopausal Women - Doctor's Guide, 6/24/03 - "the highest and lowest quintiles were at twice the risk of hip fracture compared to the middle quintile ... without knowing the vitamin A status of an individual, eliminating vitamin A supplements could actually increase the number of vitamin A-deficient individuals, which would put them at risk not only of hip fractures, but also for other health risks associated with low vitamin A"
• Children on Frequent Oral Corticosteroids Should Maintain a Lifestyle that Wards Off Osteoporosis - Doctor's Guide, 6/20/03
• Ulnohumeral Arthroplasty Improves Pain and Function in Elbow Osteoarthritis - Doctor's Guide, 5/26/03
• Anti-hip Fracture Efficacy Lost with Estrogen Cessation - Doctor's Guide, 4/29/03 - "We found a statistically significant correlation between ending estrogen and increased risk of hip fracture ... Among this sub-group, the current users showed a statistically significant reduced tendency toward hip fracture over never-users (0.10% of 67,973 vs. 0.28% of 53,737"
• Stronium Ranelate Potential New Option for Postmenopausal Osteoporosis - Doctor's Guide, 4/28/03
• Simvastatin Enhances Bone Formation And Augments Bone Mineral Density - Doctor's Guide, 4/24/03 - "After a year's treatment with simvastatin the increases in bone mineral density at the lumbar spine, femoral neck and femur were 2.8, 1.0 and 0.8% respectively. In contrast, lumbar spine, femoral neck and femur bone mineral density declined by 1.6, 1.4, and 1.2% in the control group" - Note: Red yeast rice is a non-prescription statin but you should still check with your physician.  See iHerb or Vitacost red yeast rice products.
• Boosting Bone Mineral Density Without Hormones - WebMD, 3/25/03 - "experts urge women who discontinued their hormones to get a bone mineral density test and discuss new treatments for osteoporosis with their doctor ... The statistics are staggering. One in two postmenopausal women has osteoporosis, 25% will sufferer a spine fracture, and 15% will sustain a hip fracture as a result ... Depending on the results of the test, your doctor can prescribe one of several drugs including Fosamax, Actonel, Evista, the nasal spray Miacalcin, and the newest drug on the block, Forteo, an injectable form of human parathyroid hormone"
• Growth Hormone Increase Bone Content In Osteoporotic Postmenopausal Women - Doctor's Guide, 3/12/03 - "80 osteoporotic postmenopausal women, aged between 50 and 70, who were using oestrogen therapy (HRT), were randomised to receive either recombinant human growth hormone (GH), 1.0 U or 2.5 U/day, subcutaneous, or placebo. Calcium (750 mg) and vitamin D (400 U) were given to all patients as well ... At 3 years, when GH was discontinued, total body and femoral neck bone mineral content had increased in both GH-treated groups, and differences were not significant ... At the fourth year of follow-up, total body boner mineral content had increased 5% and lumbar spine bone mineral content increased 14% among women who received GH 2.5 U, and compared with placebo. Femoral neck bone mineral density increased 5% and bone mineral content 13% for women taking GH 2.5 U compared with those taking GH 1.0 U"
• Parathyroid Hormone [hPTH] May Increase Vertebral Bone Strength In Some Postmenopausal Women - Doctor's Guide, 2/14/03
• PTHrP Leads To Significant Increase In Bone Mineral Density - Doctor's Guide, 2/5/03
• Long-Distance Runners Risk Bone Loss - WebMD, 1/27/03
• News - Inhaled Corticosteroids Do Not Affect Bone Density - Doctor's Guide, 1/24/03
• Daily Clodronate Prevents Early Postmenopausal Bone Loss - Doctor's Guide, 1/8/03
• Oral Contraceptive Use May Preserve Bone Density in Some Women - Doctor's Guide, 12/24/02
• Bone Loss Accelerated After Solo Estrogen Withdrawal For Some Postmenopausal Women - Doctor's Guide, 12/10/02 - "An acceleration of bone loss is seen after withdrawal of oestrogen therapy but not after withdrawal of alendronate alone or combination therapy with oestrogen"
• Several Bone Metabolism Factors Affect Hip Fracture Risk in Postmenopausal Women - Doctor's Guide, 12/5/02
• Micro-CT Scans Provide 3-D Proof of Estrogen's Bone Benefit - Medscape, 12/3/02 - "A three-dimensional glimpse of bone micro-architecture suggests that estrogen replacement is an effective treatment for osteoporosis because it "protects and retains bone structure, rather than laying down new bone,""
• Bone Loss in Men with Steroid Induced Osteoporosis May Be Due to Low Oesetradiol Levels - Doctor's Guide, 11/18/02
• Men With Hip Fracture Seldom Osteoporosis Therapy - Doctor's Guide, 11/13/02
• Light Exercise Won't Make Bones Strong - WebMD, 11/1/02 - "The fittest people were at just the same risk for brittle bones as those who gasped for breath after a short time on the treadmill"
• Osteoporosis Not Just for Women - WebMD, 10/28/02
• Fracture Treatment Differs - Intelihealth, 10/28/02 - "Thirty-two percent of the men died within a year of their fractures. Many deaths were likely from ailments linked to the weakened condition of being immobilized by the fractures, which may have been preventable with treatment for osteoporosis or underlying conditions that can cause it ... In men, low testosterone levels, alcoholism and excessive use of steroid medicines can cause low bone density and can often be treated"
• Hormone Therapy Plus Alendronate Better for Bone Density than Hormone Therapy Alone - Doctor's Guide, 10/8/02
• Testosterone supplementation provides additional BMD gains in hypogonadal men following cardiac transplantation - Doctor's Guide, 9/23/02 - "hypogonadal men who received additional testosterone supplementation showed the largest increases in BMD [bone mineral density]"
• Height Loss Good Index for Ruling Fracture Risk Out in General Practice Setting - Doctor's Guide, 9/23/02
• Secondary Causes of Osteoporosis Higher in Fracture Patients - Doctor's Guide, 9/23/02 - "The most common cause of secondary osteoporosis is corticosteroid excess, whereas others include malignancy, gastric surgery, alcoholism, and anticonvulsant therapy use. Prior studies have shown that as many as 30 percent of postmenopausal women exposed to corticosteroids demonstrate causes of secondary osteoporosis"
• Bisphosphonates Safe in Renally Impaired Osteoporosis Patients - Doctor's Guide, 9/23/02
• Osteoporosis Under-Recognized at Time of Admission to Nursing Home - Doctor's Guide, 9/23/02 - "New data confirm that few patients in nursing homes are on osteoporosis-related treatments despite the known high prevalence of osteoporosis in this population"
• Low Bone Mineral Density Common in Elderly Black Women - Doctor's Guide, 9/23/02 - "New findings document that 60 percent of elderly African-American women have a low bone mineral density (BMD)"
• Primary Care Residents Don't Screen for Osteoporosis - Doctor's Guide, 9/23/02 - "Primary care residents assess women who are at risk for postmenopausal osteoporosis at a rate far below that for other common health conditions ... She also pointed out that the results are regrettable since osteoporosis is a prevalent chronic health problem with associated morbidity and mortality outcomes on a par with other chronic illnesses such as hypertension, hypercholesterolemia, and diabetes. Also, the disease is preventable"
• Secondary Causes of Osteoporosis Higher in Fracture Patients - Doctor's Guide, 9/23/02 - "The most common cause of secondary osteoporosis is corticosteroid excess, whereas others include malignancy, gastric surgery, alcoholism, and anticonvulsant therapy use. Prior studies have shown that as many as 30 percent of postmenopausal women exposed to corticosteroids demonstrate causes of secondary osteoporosis"
• Low-Carbohydrate, High-Protein Diets Increase Risk Of Kidney Stones And May Raise Bone Loss Risk - Doctor's Guide, 8/1/02 - "acid excretion - a marker for the acid load in the blood - increased as much as 90 percent while subjects were on diets that severely restricted carbohydrates. Levels of urinary citrate, which inhibits kidney stones, fell by almost 25 percent in the group during the six-week study ... People may lose weight on this diet, but this study shows that this is not a healthy way to lose weight ... there was an increased risk of developing kidney stones and a possible increase in the risk of bone loss"
• Relation of Statin Use and Bone Loss: A Prospective Population-Based Cohort Study in Early Postmenopausal Women - Doctor's Guide, 7/15/02
• Osteoporosis in Elderly Men Underestimated - Doctor's Guide, 6/24/02 - "As many as 30 percent of men over 65 years old may have osteoporosis ... The serum thyroid-stimulating hormone (TSH), although normal, was slightly lower in men with osteoporosis, an average of 1.57+/-0.74 in comparison to an average of 2.34+/-1.93 in men with no osteoporosis ... Because both groups of men have low-normal 25-OH vitamin D, and low urinary calcium, the investigators suggest that patients in their situation, could benefit from enhancing their nutritional status"
• Epilepsy Drugs Are Risk Factors For Osteoporosis - Doctor's Guide, 6/20/02 - "Epilepsy and its therapies - older or modern - are both risk factors for low bone density, irrespective of vitamin D levels"
• Daily Oral Pamidronate Effective, Safe In Established Osteoporosis - Doctor's Guide, 6/17/02
• Triple Combination Incorporating Hormone Replacement May Protect Against Osteoporotic Fractures - Doctor's Guide, 6/7/02
• Irregular Periods In Young Women Could Be Warning Sign For Later Osteoporosis - Doctor's Guide, 5/29/02 - "Irregular menstrual periods in young women may be a warning sign of a hormonal shortage that could lead to osteoporosis"
• Effect of Lower Doses of Conjugated Equine Estrogens With and Without Medroxyprogesterone Acetate on Bone in Early Postmenopausal Women - JAMA. 2002 May 22-29;287(20):2668-76
• Vivelle-Dot (Estradiol Transdermal System) Now Approved In New, Low Dose For Postmenopausal Osteoporosis Prevention - Doctor's Guide, 5/21/02 - "Vivelle-Dot is now approved in the 0.025 mg/day dosage strength, providing among the lowest effective ERT dosage strengths available in the U.S. for the prevention of postmenopausal osteoporosis"
• Nandrolone Decanoate Increases Bone Mineral Density in Elderly Patients with Osteoporosis - Doctor's Guide, 5/15/02
• Strontium Ranelate Reduces Vertebral Fracture Risk in Postmenopausal Osteoporosis - Doctor's Guide, 5/15/02
• Teriparatide (Parathyroid Hormone) Increases Vertebral Bone Mineral Density in Men Irrespective of Osteoporosis Secondary Cause Factors - Doctor's Guide, 5/15/02
• Strontium Ranelate Reduces Vertebral Fracture Risk in Postmenopausal Osteoporosis - Doctor's Guide, 5/14/02
• Intermittent Oral Ibandronate Reduces Fracture Risk in Postmenopausal Women - Doctor's Guide, 5/14/02
• Reduction in Bone Turnover Markers Convenient, Practical Way to Monitor Osteoporosis Therapy - Doctor's Guide, 5/14/02
• FDA Approves New Indication, Strength of Alora (Estradiol Transdermal System) for Prevention of Postmenopausal Osteoporosis - Doctor's Guide, 4/9/02 - "These approvals add a new indication, prevention of postmenopausal osteoporosis, and a new strength, 0.025mg/day, to the Alora label"
• Protein [Runx or core binding factor A] May Help Bone Growth - Intelihealth, 4/8/02
• Investigation Of Bone Loss After Discontinuation Of Hormone Replacement - Doctor's Guide, 4/5/02
• Bone Mass Response to Discontinuation of Long-term Hormone Replacement Therapy: Results From the Postmenopausal Estrogen/Progestin Interventions (PEPI) Safety Follow-up Study - Arch Intern Med. 2002 Mar 25;162(6):665-72 - "Rates of BMD loss among women who stopped HRT during or after the PEPI-RCT [Postmenopausal Estrogen/Progestin Interventions randomized controlled trial] did not differ significantly from those of women who did not undergo HRT, who lost bone at a rate of approximately 1% yearly during the first year of the PEPI-RCT and about half that rate afterward. Women who continued HRT after the PEPI-RCT did not show additional BMD gains"
• Bone Loss Resumes at Normal Rate When Hormone Replacement Therapy is Stopped - Doctor's Guide, 3/25/02
• Risk of Fracture Reduced in Women Using Statins - Doctor's Guide, 3/19/02 - "Fracture risk is reduced by 60 percent in women using 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors (statins) ... This substantial risk reduction is greater than might be anticipated from increases in bone mineral density (BMD) alone"
• Estradiol Via Matrix Patch Reverses Bone Loss - Doctor's Guide, 3/12/02 - "Transdermal estradiol delivered by matrix patch reversed bone loss in hysterectomized, post-menopausal women and produced few side effects"
• Statin Use, Bone Mineral Density, and Fracture Risk: Geelong Osteoporosis Study - Arch Intern Med. 2002 Mar 11;162(5):537-40 - "The substantial 60% reduction in fracture risk associated with statin use is greater than would be expected from increases in BMD alone"
• Simvastin Has No Effect On Bone Formation or Resorption in Osteopenia - Doctor's Guide, 3/8/02
• Preventing Bone Loss, on a Yearly Basis - WebMD, 2/27/02
• Calcitonin Boosts Trace Minerals In Postmenopausal Osteoporotics - Doctor's Guide, 2/5/02
• Osteocalcin Tied To Bone Loss, Fracture In Elderly - Doctor's Guide, 2/5/02
• Fluoride Aids Bone Health - HealthandAge, 1/11/02
• Bisphosphonates And Hormone Replacement Preferred For Osteoporosis Prevention - Doctor's Guide, 12/18/01
• Postmenopausal Bone Loss Studied - Intelihealth, 12/12/01
• Study: Estrogen Therapy Significantly Improves Bone Density In Elderly Women - Intelihealth, 8/15/01
• Estrogen Increases Bone Mass in Women Over 75 -  WebMD, 8/14/01
• New Guidelines Recommend Bisphosphonates For Prevention, Treatment of Glucocorticoid-Induced Osteoporosis - Doctor's Guide, 7/19/01
• Increased Bone Density Following Two Years Of Growth Hormone Treatment In Men With Idiopathic Osteoporosis - Doctor's Guide, 6/24/01
• Growth Hormone, Alendronate And Tissue-Selective Estrogen All Effective In Osteoporosis - Doctor's Guide, 6/21/01
• Weekly Fosamax (Alendronate) Shows Equivalent Increases In Bone Density as Daily Regimen - Doctor's Guide, 6/20/01
• Once-Weekly Fosamax Effective For Osteoporosis - Doctor's Guide, 6/17/01
• Early Hormone-Replacement Therapy Helps Prevent Osteoporotic Fractures - Doctor's Guide, 6/14/01
• Estrogen's Benefit on Bone Questioned - WebMD, 6/12/01 - "If you're over age 60, it would seem that the evidence isn't as strong that it works. ... You might be better to consider an alternative medication where there is better evidence of effectiveness ... Those alternatives include drugs that have been proven effective for preventing and treating osteoporosis such as Evista, Fosamax, Actonel, and the hormone calcitonin"
• Fewer Gastric Ulcers With Risedronate Compared To Alendronate - Doctor's Guide, 5/25/01
• Promising New Osteoporosis Treatment Boosts Bone Growth - Intelihealth, 5/16/01 - "Injections of parathyroid hormone increase bone density and reduce the risk of fractures in the neck and spine, offering a potential new treatment for many cases of osteoporosis"
• Natural Hormone Helps Osteoporosis - Intelihealth, 5/10/01 - "A natural bone-building hormone appears to be the most effective treatment ever for osteoporosis ... The manufacturer hopes the medicine, called Forteo (for-TAY-oh), will be available by prescription by the end of the year ... drug is based on the parathyroid hormone, which is ordinarily secreted by tiny glands in the neck. When given to volunteers with osteoporosis, it doubles their normal rate of bone formation"
• It's Never Too Late to Treat Osteoporosis, Even Advanced Disease Benefits From Therapy - WebMD, 5/3/01
• New Guidelines Aim To Improve Osteoporosis Awareness Among Women And Physicians - Doctor's Guide, 5/1/01
• Childhood Cancer Survivors at Greater Risk for Osteoporosis - Doctor's Guide, 4/30/01
• Osteoporosis Supplement Doesn't Prevent Bone Loss In Study - Intelihealth, 3/20/01 - "ipriflavone, a synthetic form of an estrogen-like substance found in plants such as soybeans ... ipriflavone supplements had no effect on preserving bone density. But women who took the supplements, in standard doses of 600 milligrams daily, were more likely than those on dummy pills to develop a reduction in disease-fighting white blood cells called lymphocytes ...  The women remained otherwise healthy, but low lymphocyte counts are a symptom of an immune system that is potentially more vulnerable to infection ... The study was funded by Chiesi Pharmaceuticals Inc., an Italian maker of ipriflavone (so it may have been that brand)"
• Ultrasound Takes Osteoporosis by the Heel, New Device Might Replace Bone Scans - WebMD, 2/20/01
• Fatty diet could lead to thin bones -- study - CNN, 12/20/00
• Kids Taking Steroids for Asthma Need Calcium and Exercise - WebMD, 10/20/00
• Early Intervention In Osteoporosis Vital In Effective Treatment - Doctor's Guide, 10/3/00
• Study Raises Serious Questions About Osteoporosis Care - Doctor's Guide, 8/25/00
• FDA Approves Vivelle (estradiol transdermal system) For Postmenopausal Osteoporosis - Doctor's Guide, 8/18/00
• Cholesterol-Lowering Drug May Protect Women From Bone Fractures - Intelihealth, 6/23/00
• Parathyroid Hormone - Newest Treatment On Horizon For Osteoporosis - Doctor's Guide, 6/19/00
• Bone Loss In Osteoporosis Still Not Detected Early Enough To Prevent Fractures - Doctor's Guide, 6/16/00
• Majority Of Women Treated For Osteoporosis Not Taking Calcium Supplements - Doctor's Guide, 6/15/00
• Rheumatoid Arthritis Patients at Higher Risk for Bone Loss - WebMD, 4/28/00
• FDA Approves Activella (Estradiol/Norethindrone ) For Prevention Of Postmenopausal Osteoporosis - Doctor's Guide, 4/14/00
• NIH Panel Issues Statement on Osteoporosis Prevention, Diagnosis, and Treatment - Doctor's Guide, 3/29/00
• Mysterious Foot Fractures May Be Sign Of Osteoporosis - Doctor's Guide, 3/21/00
• Contradictory Findings: Fluoride Does Increase Risk Of Hip Fractures - Doctor's Guide, 2/24/00
• Men With Chronic Lung Disease At High Risk For Osteoporosis - Doctor's Guide, 12/14/99
• Cholesterol-lowering drugs may lead to osteoporosis treatments - CNN, 12/3/99
• Testosterone Therapy Effective For Men With Osteoporosis - Doctor's Guide, 11/17/99
• Newest drug for osteoporosis has fewer side-effects - CNN, 10/13/99
• Spinal Fractures Linked To Lower Quality of Life, Increased Risk of Depression - Doctor's Guide, 10/4/99
• Researchers Link Hypertension And Osteoporosis - Doctor's Guide, 9/17/99
• Treatment Options For Preventing Osteoporosis - Doctor's Guide, 5/19/99
• Prostate Cancer Therapy Adds To Men's Osteoporosis Risk - Intelihealth, 5/18/99
• Corticosteroid Treatment Increased Risk Of Vertebral Fracture - Doctor's Guide, 12/14/98
• Majority Of American Women Unaware Of Most Common Osteoporosis Fracture Site - Doctor's Guide, 12/4/98
• Osteoporosis Linked With Lung Disease In Men, Says Study - Doctor's Guide, 11/10/98
• Guidelines to prevent, diagnose and treat osteoporosis expected - CNN, 11/5/98
• Osteoporosis And Oral Health Closely Linked, Study Shows - Doctor's Guide, 2/16/98
• Majority Of Fracture Patients Not Investigated For Osteoporosis - Doctor's Guide, 1/23/98
• Biphosphonates May Help Avoid Corticosteroid-Induced Osteoporosis - Doctor's Guide, 11/10/97
• Misconceptions Keep Some Wormen for Taking Action on Osteroporosis - Doctor's Guide, 10/9/97
• National Osteoporosis Foundation Comments On New Osteoporosis Study - Doctor's Guide, 9/11/97
• Women Confuse Bone-Thinning Disease with Arthritis - Doctor's Guide, 7/2/97
• PMS Management Prevents Osteoporosis - Doctor's Guide, 5/30/97

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