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Recent Longevity News for the seven days ending 7/11/07. You should consult your doctor if you are taking any medications.
Low testosterone may risk heart - BBC News, 7/9/07 - "Post-menopausal women with low levels of the male sex hormone testosterone are more likely to develop heart disease ... Those with atherosclerosis had much less testosterone than those without"
Selenium Supplements: Diabetes Risk - WebMD, 7/9/07 - "During the study, 58 participants in the selenium group reported being diagnosed with type 2 diabetes, compared with 39 people taking the placebo"
Kids' Bones at Risk From Low Vitamin D - WebMD, 7/9/07 - "55% of the children had lower than recommended vitamin D levels ... Overall, 68% of children had inadequate stores of the vitamin in their blood during the colder months when they spent more time indoors" - See vitamin D products at iHerb.
Folate may reduce liver damage study - Nutra USA, 7/6/07 - "higher red blood cell folate levels were associated with a 67 per cent reduced risk of liver cancer" - [Abstract] - See iHerb folic acid products.
Lower Bone Mineral Density Found in Older Men Using SSRIs - Medscape, 7/6/07 - "SSRI use was associated with lower mean BMD at the hip and spine, but there was no significant difference among users of TCAs or trazodone hydrochloride and nonusers"
SSRI Use in Older Women Linked to Accelerated Hip Bone Loss - Medscape, 7/6/07 - "Women not taking SSRIs lost bone density at a rate of about 0.5% per year, and the women taking SSRIs lost bone density at a rate of about 0.8% per year"
Fitness Reduces Inflammation, Study Suggests - Science Daily, 7/6/07 - "the research “certainly suggests that fitness may be associated with a decrease in inflammation even independent of body fat and several things, and the mechanism may involve a parasympathetic anti-inflammatory reflex"
Why Liver Cancer Is More Prevalent In Males Than In Females - Science Daily, 7/5/07 - "By eliminating IL-6, we reduced the incidence of liver cancer in the males by close to 90%"
Diabetes Drug Avandia: Heart Disease Risk Inconclusive? - WebMD, 7/5/07 - "The researchers note that they can't tell yet if there is an association between Avandia and heart attacks or Avandia and heart disease in general"
Older Patients Reap Positive Benefits With High Dose Statins, Study Finds - Science Daily, 7/3/07 - "The study participants had a relative reduction in risk of 19 percent for a major cardiovascular event with high-dose compared with low-dose atorvastatin. The important feature is that this occurred without any evidence of increase in risk from the high dose"
Abstracts from this week's Doctor's Guide Nutrition/Dietetics plus abstracts from my RSS feeds:
Pioglitazone Decreases Ambulatory Blood Pressure in Type 2 Diabetics With Difficult-to-Control Hypertension - J Clin Hypertens (Greenwich). 2007 Jul;9(7):530-7 - "add-on therapy with pioglitazone 30 to 45 mg for 20 weeks. After 20 weeks of treatment, 24-hour ambulatory BP monitoring showed significant reductions (from 144+/-13 to 136+/-16 mm Hg systolic BP and from 79+/-9 to 76+/-10 mm Hg diastolic BP [P=.001]). Treatment was also associated with improvements in insulin sensitivity and glycemic and lipid profile"
Anti-ageing effect of a lactococcal strain: analysis using senescence-accelerated mice - Br J Nutr. 2007 Jul 9;:1-9 - "Oral administration of heat-killed Lactococcus lactis subsp. cremoris H61 (strain H61) to aged SAMP6 mice was associated with reduced bone density loss, a suppression of incidence of skin ulcers and reduced hair loss, compared with controls"
Tomato juice decreases LDL cholesterol levels and increases LDL resistance to oxidation - Br J Nutr. 2007 Jul 9;:1-8 - "a high dietary intake of tomato products had atheroprotective effects, it significantly reduced LDL cholesterol levels, and increased LDL resistance to oxidation in healthy normocholesterolaemic adults. These atheroprotective features associated with changes in serum lycopene, beta-carotene and gamma-carotene levels"
Beneficial effects of a 5-week low-glycaemic index regimen on weight control and cardiovascular risk factors in overweight non-diabetic subjects - Br J Nutr. 2007 Jul 9;:1-11 - "Mean body weight decrease was significant in the LGI group ( - 1.1 (sEM 0.3) kg, P = 0.004) and was significantly greater than in the HGI group ( - 0.3 (sEM 0.2) kg, P = 0.04 between groups). Hunger sensation scales showed a trend towards a decrease in hunger sensation before lunch and dinner in the LGI group when compared with the HGI group (P = 0.09). No significant increase in insulin sensitivity was noticed. The LGI diet also decreased total cholesterol by 9.6 % (P < 0.001), LDL-cholesterol by 8.6 % (P = 0.01) and both LDL-:HDL-cholesterol ratio (10.1 %, P = 0.003) and total:HDL-cholesterol ratio (8.5 %, P = 0.001) while no significant changes were observed in the HGI group"
Bone mineral density and bone markers in patients with a recent low-energy fracture: effect of 1 y of treatment with calcium and vitamin D - Am J Clin Nutr. 2007 Jul;86(1):251-9 - "A 1-y intervention with calcium and vitamin D reduced bone turnover, significantly increased BMD in patients younger than 70 y, and decreased bone loss in older patients. The effect of treatment was related to physical performance"
Association between dietary glycemic index and age-related macular degeneration in nondiabetic participants in the Age-Related Eye Disease Study - Am J Clin Nutr. 2007 Jul;86(1):180-8 - "Compared with eyes in the first quintile of dGI, eyes in the fourth and fifth quintiles had a significantly or suggestively higher risk of large drusen, geographic atrophy, and neovascularization. The multivariate-adjusted odds ratios (95% CIs) for the highest quintile were 1.42 (1.09, 1.84), 1.78 (0.81, 3.90), and 1.41 (0.95, 2.08), respectively, of which only the odds ratio for large drusen was significant. A significant positive relation between dGI and severity of AMD was also noted (P for trend < 0.001). There was a 49% increase in the risk of advanced AMD (geographic atrophy plus neovascularization) for persons with a dGI higher than the sex median"
Blood folate levels and risk of liver damage and hepatocellular carcinoma in a prospective high-risk cohort - Cancer Epidemiol Biomarkers Prev. 2007 Jun;16(6):1279-82 - "When comparing persons in the lowest quartile RBC folate to persons in all other quartiles, the analysis found that higher RBC folate levels were associated with reduced risk of hepatocarcinogenesis (odds ratio, 0.33" - See iHerb folic acid products.
Flavonoids and the risk of renal cell carcinoma - Cancer Epidemiol Biomarkers Prev. 2007 Jan;16(1):98-101 - "After adjustment for major recognized confounding factors and total energy intake, the odds ratios for subjects in the highest versus the lowest quintile of intake were 0.80 [95% confidence interval (95% CI), 0.58-1.11] for total flavonoids, 0.76 (95% CI, 0.56-1.03) for isoflavones, 0.94 (95% CI, 0.60-1.47) for anthocyanidins, 0.77 (95% CI, 0.56-1.06) for flavan-3-ols, 0.90 (95% CI, 0.67-1.21) for flavanones, 0.68 (95% CI, 0.50-0.93) for flavones, and 0.69 (95% CI, 0.50-0.95) for flavonols"
High-normal fasting blood glucose in non-diabetic range is associated with increased coronary artery calcium burden in asymptomatic men - Atherosclerosis. 2007 Jun 30 - "coronary artery calcium (CAC) ... The prevalence of CAC was significantly higher among men with high-normal FBG (4th quartile: 94-125mg/dl) versus normal FBG group (lower three quartiles: 66-93mg/dl) (62% versus 35%, p<0.0001). In age adjusted analyses the odds ratio (OR) for any CAC among men with high-normal FBG versus normal FBG was 2.19" - See my Insulin and Aging page.
Associations of salivary cortisol with cognitive function in the Baltimore memory study - Arch Gen Psychiatry. 2007 Jul;64(7):810-8 - "Higher levels of pretest and mean cortisol as well as the area under the curve of cortisol over the study visit were associated with worse performance (P < .05) in 6 domains (language, processing speed, eye-hand coordination, executive functioning, verbal memory and learning, and visual memory). For instance, an interquartile range increase in the area under the curve was equivalent to a decrease in the language score expected from an increase in 5.6 (95% confidence interval, 4.2-7.1) years of age" - See my cortisol page for ways to reduce it.
Correlation between vitamin D(3) deficiency and insulin resistance in pregnancy - Diabetes Metab Res Rev. 2007 Jul 2 - "Total prevalence of vitamin D deficiency (<25 nmol/L) was found in 70.6% of pregnant women ... These results show that a positive correlation of 25(OH) vitamin D concentrations with insulin sensitivity and vitamin D deficiency could be a confirmative sign of insulin resistance"
The impact of thiazolidinedione use on outcomes in ambulatory patients with diabetes mellitus and heart failure - J Am Coll Cardiol. 2007 Jul 3;50(1):32-6 - "In ambulatory patients with established HF and diabetes, the use of TZDs was not associated with an increased risk of HF hospitalization or total mortality when compared with those not receiving insulin-sensitizing medications"
Effects of folic acid and vitamin B complex on serum C-reactive protein and albumin levels in stable hemodialysis patients - Curr Med Res Opin. 2007 Jun 29 - "Folic acid and vitamin B complex co-administration effectively lowers tHcy and hs-CRP levels and increases albumin levels in stable hemodialysis subjects, underscoring their potential benefit to attenuate the state of inflammation and possibly improve the nutritional status in patients on hemodialysis"
I just purchased a new computer with Windows Vista Ultimate. I had a heck of a time figuring out how to configure the Remote Desktop Connecting feature using a Linksys router. When I finally figured it, I made a web page to show how to do it. Click here for the instructions. You'll need Microsoft Windows XP Professional or Windows Vista Ultimate for the feature to work. It's a neat feature. You can log unto your computer from anywhere in the world and it's like having you computer right in front of you.
Health Focus (aromatization/gynecomastia):
Affiliates (I could sure use some sales. You can drag the links onto your desktop and use them so that I get credit for the sale. Click here for more stores):
Oxytocin 24 x 20iu sublingual Troches at IAS
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