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Anti-aging Research > Ursolic Acid
News & Research:
Apple peel compound boosts brown fat, reduces obesity in mice - Science
Daily, 6/20/12 - "The findings suggest that the
substance known as ursolic acid reduces obesity and its associated health
problems by increasing the amount of muscle and brown fat, two tissues
recognized for their calorie-burning properties ... In this study, we tested
ursolic acid in mice on a high-fat diet -- a mouse model of obesity and
metabolic syndrome. Once again, ursolic acid increased skeletal muscle.
Interestingly, it also reduced obesity, pre-diabetes and fatty liver disease
... Since muscle is very good at burning calories, the increased muscle in
ursolic acid-treated mice may be sufficient to explain how ursolic acid
reduces obesity. However, we were surprised to find that ursolic acid also
increased brown fat, a fantastic calorie burner. This increase in brown fat
may also help protect against obesity" - See
ursolic acid products at iHerb.
Combined Treatment with Ursolic Acid and Resveratrol on Skin Tumor Promotion by
12-O-tetradecanoylphorbol-13-acetate - Cancer Prev Res (Phila).
2015 Jun 22 - "Treatment with UA + Res during skin tumor promotion with TPA
produced greater inhibition of tumor multiplicity and tumor size than with
either agent alone. Collectively, the greater ability of the combination of UA +
Res to inhibit skin tumor promotion was due to the greater inhibitory effects on
growth factor and inflammatory signaling, skin inflammation and epidermal hyperproliferation induced by TPA treatment" -
ursolic acid at Amazon.com
ReserveAge Resveratrol Vegetarian Capsules, 500 Mg, 60-Count
increases energy expenditure through enhancing free fatty acid uptake and
β-oxidation via an UCP3/AMPK-dependent pathway in skeletal muscle - Mol Nutr
Food Res. 2015 May 5 - "In diet-induced obese rats, 0.5% UA supplementation for
6 weeks markedly reduced body weight, increased energy expenditure, decreased
FFA level in serum and skeletal muscle and triglyceride content in skeletal
muscle ... UA increases FFA burning through enhancing skeletal muscle FFA uptake
and β-oxidation via an UCP3/AMPK-dependent pathway, which provides a novel
perspective on the biological function of UA against obesity and IR"
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