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Home > Anti-aging Research > TMG

Trimethylglycine or Dimethylglycine

Specific Recommendations:

News & Research:

  • Legal Performance Enhancer Discovered in the Nutrient Betaine - Science Daily, 7/5/13 - "betaine -- a nutrient found in shellfish and beets -- boosts athletic performance by nearly six percent when added to a sports drink ... Betaine may contribute to creatine synthesis, which improves, strength, power and short-term performance ... researchers suggest: Dissolve 2.5 grams of betaine (either powder or tablet form) in a 20-ounce sports drink, and drink half in the morning and half in the afternoon" - See trimethylglycine at Amazon.com.
  • Danisco extends betaine’s sport science - Nutra USA, 8/13/09 - "During various power, muscle endurance and anaerobic power exercise tests over a two week period, subjects given BetaPower showed a significant improvement in lower body muscle endurance and quality of the workout compared to those participants that were not given supplementation" - [Abstract]
  • Startling New Findings About Homocysteine - Life Extension Magazine, 11/03 - "a startling 100% of French elderly hospitalized patients showed higher than desired homocysteine levels, with 45% suffering from severe hyperhomocysteinemia ... Administration of vitamins B6 and B12, and folate, causes a significant decrease of elevated serum homocysteine concentrations in older persons ... More recent studies not only confirm the cardiovascular dangers of homocysteine, but also its toxic effect on the brain. It turns out that high blood levels of homocysteine increase the incidence of depression, memory impairment, and even Alzheimer’s disease"
  • The Benefits of CLA Too Good To Be True? - Life Extension Magazine, 6/99 - "TMG may be one of the most important nutrients to prevent heart disease, stroke, liver disease, slow aging and treat depression. TMG is also called glycine betaine, but the name "trimethylglycine" signifies that it has three methyl groups attached to each molecule of glycine. In the body, TMG donates one of its methyl groups to cellular DNA, which may help protect DNA against damage and its consequences, cancer and premature aging. When a TMG methyl group is donated to a molecule of homocysteine, it is converted first to methionine then to s-adenosyl-methionine (SAM). No "safe" level of homocysteine has been established, suggesting that taking nutrients like TMG could lower everyone's risk of heart attack and stroke, in addition to protecting DNA."
  • SAMe Needs The B's - Nutrition Science News, 7/00 - "users of this wonder pill should be aware that through the natural metabolism of SAMe, the amino acid homocysteine is created--a situation that can lead to artery damage and even heart disease. . . . .others have demonstrated that by simply upping one's intake of the vitamins B6, B12 and folic acid, this potential hazard can be avoided." (Note:  TMG is a precursor to SAM-e and lowers homocysteine instead of raising it.)
  • Diet, Supplements, Exercise and Sauna - Life Extension Magazine, 9/99 - "TMG, on the other hand, is very effective at raising the levels of SAMe and lowering homocysteine."
  • Dimethylglycine , dimethylglycine research, dimethylglycine benefits - Dr. Sahelian