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Anti-aging Research > Shiitake
Shiitake (Lentinus edodes)
News & Research:
extract, AHCC, helpful in treating HPV - Science Daily, 10/28/14 -
HPV-positive women were treated orally with the extract, AHCC (active hexose
correlated compound) once daily for up to six months. Five achieved a negative
HPV test result -- three with confirmed eradication after stopping AHCC -- with
the remaining two responders continuing on the study ... Currently, there is no
effective medicine or supplement to treat HPV, which is associated with more
than 99 percent of cervical cancer cases ... several other cancers are related
to HPV, including 95 percent of anal cancer, 60 percent of oropharyngeal, 65
percent of vaginal cancer, 50 percent of vulvar cancer and 35 percent of penile
cancer ... AHCC increases the number and/or activity of Natural Killer (NK)
cells, dendritic cells and cytokines, which help the body fight off infections
and block tumor growth" - See AHCC at Amazon.com.
healing power of mushrooms - Fox News, 4/4/12 -
"Shiitake ... The mushroom contains a polysaccharide called lentinan, and
another known as Beta 1.3 glucan, both of which appear to possess powerful
anti-viral and anti-tumor powers ... Shiitake also enhances immunity by boosting
the production of T cells, macrophages, phagocytes, natural killer cells and
other white blood cells. It even helps to fight flu, due to the presence of a
polysaccharide known as KS-2. Further clinical studies show that Shiitake even
protects against the damaging effects of radiation and chemotherapy ...
consumption of shiitake leads to a drop in serum cholesterol of between 7 and 12
percent. Russian and U.S. studies show that shiitake inhibits platelet
aggregation in the blood, thereby reducing the buildup of arterial plaque -
which is the cause of hardened arteries. This mushroom also inhibits the
formation of arterial lesions, and lowers high blood pressure ... Reishi
mushrooms fight tumors, presumably due to the presence of the polysaccharide
Beta 1.3, which occurs in shiitake. Reishi also increases immune-protective T
cells and macrophages ... Reishi protects the liver from damage by chemical
toxins such as carbon tetrachloride ... Maitake ..."
Mushroom extract demonstrates immunity benefits - Nutra USA, 8/25/08 -
"measured the production of two cytokines –
Interferon (IFN-y) and Tumor Necrosis Factor (TNF-a) – for 30 and 60 days ...
These cytokines are produced by white blood cells and used by the body to
prevent the growth of abnormal and cancerous cells ... the production of IFN-y
and TNF-a increased within four weeks of taking the recommended of AHCC and
continued to boost the immune system for at least four weeks after AHCC
consumption stopped" - See
AHCC at Amazon.com.
Shiitake Mushrooms May Improve Human Immune Function, Especially If Grown On
Old Oak Logs - Science Daily, 6/29/08 - "These
mushrooms contain high-molecular-weight polysaccharides (HMWP), which some
studies suggest may improve human immune function. Other research indicates
that the shiitake compound eritadenine may help lower cholesterol levels"
A case-control study on the dietary intake of mushrooms and breast cancer
risk among Korean women - Int J Cancer. 2007 Oct 17 -
"Both the daily intake (5th vs. 1st quintile, OR =
0.48, 95% CI = 0.30-0.78, p for trend 0.030) and the average consumption
frequency of mushrooms (4th vs. 1st quartile, OR = 0.54, 95% CI = 0.35-0.82,
p for trend 0.008) were inversely associated with breast cancer risk"
maitake at Amazon.com
shiitake mushroom supplements at Amazon.com.
Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity:
A Randomized Dietary Intervention in Healthy Young Adults - J Am
Coll Nutr. 2015 Apr 11:1-10 - "Eating L.
edodes for 4 weeks resulted in increased ex vivo proliferation of
γδ-T (60% more, p < 0.0001) and NK-T (2-fold more, p < 0.0001)
cells. Both cell types also demonstrated a greater ability to
express activation receptors, suggesting that consuming mushrooms
improved cell effector function. The increase in sIgA implied
improved gut immunity. The reduction in CRP suggested lower
inflammation. The pattern of cytokines secreted before and after
mushroom consumption was significantly different; consumption
resulted in increased interleukin (IL)-4, IL-10, tumor necrosis
factor (TNF)-α, and IL-1α levels, a decreased macrophage
inflammatory protein-1α/chemokine C-C ligand 3 (MIP-1α/CCL3) level,
and no change to IL-6, IL-1β, MIP-1β, IL-17 and interferon (IFN)-γ
levels" - [Science
Daily] - See
Shiitake mushroom supplements at Amazon.com.
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