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Home > Anti-aging Research > Saturated Fat

Saturated Fat

News & Research:

  • Re-Analysis Refutes Diet Guidelines Favoring Vegetable Fats - WebMD, 2/6/13 - "The first group was told to consume linoleic acid, in the form of safflower oil and safflower oil polyunsaturated margarine, at levels equal to 15 percent of total calorie intake. This, said Ramsden, is equivalent to roughly twice the amount that Americans currently consume ... While omega-3 consumption was not affected, the men were also asked to lower their saturated fat intake so that it made up less than 10 percent of their diets. They did so by substituting safflower oil for animal fats ... The second group continued their routine nutritional habits ... By newly crunching all the original data the NIH team found that, compared to the no-dietary-change group, the linoleic acid group faced a higher risk of death, from both heart disease specifically as well as from all causes overall ... the NIH team found no evidence to support the notion that linoleic acid confers health benefits. The review highlighted the possibility that boosting omega-6 consumption may actually increase the risk for developing heart disease ... Polyunsaturates are not just involved in cholesterol-lowering. They may also be involved in inflammation, oxidation or clotting"
  • New link between high-fat 'Western' diet and atherosclerosis identified - Science Daily, 10/8/12 - "endothelial lipase (EL), an enzyme associated with the development of atherosclerosis ... In the current study, a strain of mice susceptible to atherosclerosis was fed a normal diet enriched with either palmitic acid (a common saturated fat) or eicosapentaenoic acid (an omega-3 fatty acid, or polyunsaturated fat, found in fish oil, among other foods). After 12 weeks, the mice's aortas were examined for changes in the expression of EL and inflammatory factors. Aortas of mice fed the saturated fat diet showed a significant increase in EL and detrimental changes in inflammatory factors, while those of mice fed the polyunsaturated fat diet showed a significant decrease in EL and beneficial changes in inflammatory factors ... when the macrophages were given rosiglitazone, the expression of EL increased markedly. The addition of omega-3 fatty acids to the cells blocked this increase. "This would suggest that besides raising LDL cholesterol levels, rosiglitazone can raise the risk of cardiovascular disease by increasing EL,"" - See Mega Twin EPA at iHerb and Jarrow Max DHA at iHerb.
  • Fatty diets may be associated with reduced semen quality - Science Daily, 3/14/12 - "The study of 99 men in the USA found an association between a high total fat intake and lower total sperm count and concentration. It also found that men who ate more omega-3 polyunsaturated fats (the type of fat often found in fish and plant oils) had better formed sperm than men who ate less ... if men make changes to their diets so as to reduce the amount of saturated fat they eat and increase their omega-3 intake, then this may not only improve their general health, but could improve their reproductive health too ... the relationship between dietary fats and semen quality was largely driven by the consumption of saturated fats. Men consuming the most saturated fats had a 35% lower total sperm count than men eating the least, and a 38% lower sperm concentration"
  • Mediterranean Diet May Protect Brain - WebMD, 2/13/12 - "white matter hyperintensity volume (WMHV) ... WMHV is an indicator of small blood vessel damage in the brain and is detected by magnetic resonance screening (MRI) ... researchers compared the brain scans and diets of 966 adults with an average age of 72 ... those who most closely followed a Mediterranean diet had a lower measure of WMHV than those who did not. Each increase in the Mediterranean diet score was associated with a corresponding decrease in white matter hyperintensity volume score ... the aspect of the Mediterranean diet that seemed to matter most was the ratio of monounsaturated fat to saturated fat"
  • High dietary fat, cholesterol linked to increased risk of breast cancer - Science Daily, 1/6/11 - "This mouse model is believed to closely parallel the pathogenesis of human breast cancer. PyMT mice were placed on a diet that contained 21.2 percent fat and 0.2 percent cholesterol, reflective of a typical Western diet. A control group of PyMT mice was fed a normal chow that had only 4.5 percent fat and negligible amounts of cholesterol ... tumors began to develop quickly in mice fed the fat/cholesterol-enriched chow. In this group, the number of tumors was almost doubled, and they were 50 percent larger than those observed in mice that ate a normal diet. "The consumption of a Western diet resulted in accelerated tumor onset and increased tumor incidences, multiplicity, and burden, suggesting an important role for dietary cholesterol in tumor formation," ... There was also a trend towards an increased number of lung metastasis in mice fed the fatty diet"
  • How Saturated Fatty Acids 'Anger' The Immune System (And How To Stop Them) - Science Daily, 11/5/09
  • Dietary Fat Linked To Pancreatic Cancer - Science Daily, 6/26/09 - "Participants who consumed high amounts of saturated fats had 36% higher relative rates of pancreatic cancer compared with those who consumed low amounts"
  • High-fat Diet Could Promote Development Of Alzheimer's Disease - Science Daily, 10/28/08 - "the main neurological markers for Alzheimer's disease are exacerbated in the brains of mice fed a diet rich in animal fat and poor in omega-3s"
  • Memory Loss Linked To Poor Diet, Study Suggests - Science Daily, 6/19/08 - "Researchers from the Medical University of South Carolina (MUSC) have linked memory loss to a diet high in saturated fat and cholesterol"
  • Diet High In Saturated Fat Contributes To Prostate Cancer Treatment Failure, Study Suggests - Science Daily, 5/8/08 - "Patients on a HSF diets were significantly more likely to have a PSA failure and had significantly shorter PSA-failure free survival than men on a LSF diet (26.6 vs. 44.7 months, respectively). At 5 years post radical prostatectomy, 65% of patients who consumed HSF diets had no evidence of prostate cancer compared to 80% of men who ate a LSF diet"
  • Even One Fatty Meal Affects Arteries - WebMD, 8/8/06
  • Diet High in Saturated Fat May Reduce Protective Effect of HDL - Medscape, 8/7/06 - "The anti-inflammatory activity of HDL appears to decrease after consumption of saturated fat, but improves on consumption of polyunsaturated fat"
  • Saturated fats are worse than you think - MSNBC, 5/19/06 - "too much saturated fat may be problematic, even if your cholesterol isn’t high, because of its possible effects on insulin functions, potentially raising the risk of diabetes, cancer, ovarian disorders and other health problems"
  • Burger Diet Raises Breast Cancer Risk - WebMD, 7/15/03 - "The increase was most closely linked with animal fat -- specifically from animal fat -- and, more specifically, red meat and high-fat dairy foods"

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