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Home > Health Conditions > Prostatitis

Prostatitis

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  • Androgen-independent Effects of Serenoa repens Extract (Prostasan®) on Prostatic Epithelial Cell Proliferation and Inflammation - Phytother Res. 2011 Jun 8 - "Prostasan® inhibited epidermal growth factor (EGF) and lipopolysaccharide (LPS) induced proliferation of the prostatic epithelial, androgen independent cell line PC-3. At effective concentrations of 50 µg/mL, Prostasan® partly displaced EGF from EGF receptor (EGFR) but fully blocked EGF-induced cell proliferation of PC-3 cells. Similarly, Prostasan® inhibited LPS-induced proliferation of PC-3 cells without affecting LPS activation of the NFĸB pathway via toll-like receptor-4 (TLR-4). Additionally, Prostasan® reduced the constitutive secretion of monocyte chemotactic protein-1 (MCP-1), the LPS-induced secretion of IL-12 and inhibited MCP-1 and granulocyte-macrophage colony-stimulating factor (GM-CSF) production in the presence of LPS on PC-3 cells. Taken together, our results suggest that S. repens extracts, in addition to other reported effects on BPH development and prostatitis, inhibits EGF-dependent growth and proinflammatory responses of the prostate epithelial cells" - See Prostasan at Amazon.com.
  • Saw Palmetto Extract Effective in Treating Chronic Prostatitis - Medscape, 4/28/03 - "Permixon, a compound extracted from the fruit of the American dwarf palm tree Serona repens, also known as saw palmetto, appears to improve symptoms of chronic prostatitis/chronic pelvic pain syndrome ... Seventy-five percent of the patients who received Permixon had at least mild improvement in symptoms compared with 20% of the control group. Similarly, 55% of patients who received Permixon reported moderate or marked improvement compared with 16% of the control group ... In the control group, PSA did not differ from baseline. However, the group taking Permixon experienced median decreases from baseline PSA of 22% after 6 weeks" - See iHerb saw palmetto products.
  • Quercetin Relieves Prostate Pain - Nutrition Science News, 7/01
  • Quercetin Is Promising for Chronic Prostatitis - Nutrition Science News, 4/01 - "an encouraging 59 percent of the subjects improved"
  • New Study Offers Hope for Chronic Prostatitis Treatment - Medscape, 1/00 - "More than 80% of chronic prostatitis patients who took a proprietary formulation of quercetin, a natural dietary supplement, significantly reduced pain and improved their quality of life, according to a new study published in the December issue of Urology"
  • Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial - Urology 1999 Dec;54(6):960-963 - "Therapy with the bioflavonoid quercetin is well tolerated and provides significant symptomatic improvement in most men with chronic pelvic pain syndrome"
  • Evidence for a local action of melatonin on the rat prostate - J Urol 1998 Mar;159(3):1069-1073 - "The results demonstrate putative melatonin receptors in the rat prostate and suggest a direct suppression by melatonin of testosterone-dependent prostate growth" - See my melatonin page
  • Melatonin as anti prostatitis - prostatitis.org

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