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Anti-aging Research > Prolactin
Specific Recommendations (to lower prolactin):
Acute effects of LI 160 (extract of Hypericum perforatum, St John's wort)
and two of its constituents on neuroendocrine responses in the rat - J
Psychopharmacol. 2000;14(4):360-3 - "LI
160 also lowered plasma prolactin and prevented the increase in plasma
prolactin following haloperidol administration"
Yourself from AGE - Life Enhancement Magazine, 8/00 - with American
"The researchers found a reduction in plasma
prolactin, a hormone connected with passive "nesting" behavior, suggesting
that this may play a role in the ability of American ginseng to stimulate
sexual activity in the male rat."
Spring Come Sooner - Life Enhancement Magazine, 4/98 -
"After administration of 5-HTP, the cortisol level
significantly increased and the prolactin level significantly decreased.
High levels of prolactin have been shown to reflect many depressive states."
SeroTonic™ & 5-HTP Slim™ May Help Make Spring Come Sooner - Life
Enhancement Magazine, 4/98 -
"High levels of prolactin have been shown to reflect
many depressive states ... 5-HTP reduces prolactin"
20 - The Hypericum Homepage - "Both serum-cortisol and serum-prolactin
were lowered significantly after three weeks of treatment with hypericum
extract in male rats."
Pyridoxine (Vit. B6) decreases opioids-induced hyperprolactinemia - Horm
Metab Res. 1985 Jan;17(1):46-7
Pyridoxine (B6) suppresses the rise in prolactin and increases the rise in
growth hormone induced by exercise - N Engl J Med. 1982 Aug
Inhibition of prolactin by pyridoxine - Am J Obstet Gynecol. 1979 Sep
Effects of pyridoxine hydrochloride (vitamin B6) on chlorpromazine-induced
serum prolactin rise in male rats - J Pharm Sci. 1979 Sep;68(9):1179-81
"Pyridoxine hydrochloride significantly suppressed
the chlorpromazine-induced prolactin rise"
(Parlodel®) - International Anti-aging Systems
Men's sexual desire linked to prolactin levels - NBC News.com, 11/20/13
- "researchers looked at nearly 3,000 European men
ages 40 to 79, and measured their testosterone and prolactin levels, body
mass indexes (BMIs), and blood cholesterol and sugar levels ... low
prolactin was linked to several signs of poor sexual health, as well
psychological health. Men with levels of prolactin that were lower than
average, although still within the normal range, were more likely than men
with higher levels to say their sexual function was getting worse,
particularly their enjoyment of orgasm. They also had more symptoms of
depression ... Low prolactin was also associated with higher BMI and blood
sugar, lower levels of physical activity, and generally feeling unhealthier
... Studies have found that high prolactin levels in men are linked to low
sexual desire and erectile dysfunction, and men suffering from such
conditions are sometimes tested for high prolactin levels ... Some previous
research supports the new finding, the researchers said. Two animal studies
have shown that using drugs to increase prolactin levels in rats boosted
their sexual behavior"
and Treatment of Male Sexual Dysfunction - American Association of
Clinical Endocrinologists and The American College of Endocrinology -
"increased prolactin levels may also cause erectile
problems, even in the presence of a normal testosterone level."
- Erectile Dysfunction /
Impotence - Prostate Health Guide - U. of Maryland Medicine -
"Hormonal abnormalities such as increased prolactin
(a hormone produced by the anterior pituitary gland), steroid abuse by
body-builders, too much or too little thyroid hormone, and hormones
administered for prostate cancer may cause impotence. Rarely is low
testosterone responsible for impotence"
Prolactin blocks oncogene associated with poor prognosis in breast cancer
- Science Daily, 2/3/10
Hormone Prolactin Reduces Fat Metabolism - Science Daily, 4/2/09
Antipsychotic-Induced Hyperprolactinemia - Medscape, 10/1/07
Antipsychotic Treatment: When to Measure Prolactin - Clinical Psychiatry
Antipsychotic Medications Vary In Effect On Plasma Prolactin Levels -
Doctor's Guide, 2/10/04
Cabergoline May Be Safely Withdrawn From Select Patients With
Hyperprolactinomas - Doctor's Guide, 11/21/03
Aripiprazole Benefits Are Sustained Over Time - Clinical Psychiatry
News, 5/03 -
"Its principal advantage over other atypical agents
remains a superior side effect profile; no apparent difference in efficacy
exists ... It's not the new clozapine (Clozaril) ... it seems clearly
superior in areas that have been problematic, notably weight gain, effects
on blood lipids and glucose, and prolactin elevation ... in fact, they lost
weight overall, with the heaviest patients losing most ... Pooled data from
short-term clinical studies showed a mean decline of 57% in serum prolactin"
Prolactin Not A Pro-Inflammatory In Polymyalgia Rheumatica - Doctor's
Hyperprolactinemia May Have Reproductive And Other Clinical Morbidities
- Doctor's Guide, 8/8/01
Prolactin Linked To Breast Cancer - Life Extension Magazine, 6/99
Investigations of Erectile Dysfunction - WebMD
- Dostinex Launched for
Pituitary Gland Disorders - Doctor's Guide, 3/18/97
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