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Anti-aging Research > Pregnenolone
News & Research:
Pregnenolone sulphate enhances spatial orientation and object discrimination
in adult male rats: evidence from a behavioural and electrophysiological
study - Behav Brain Res. 2013 Oct 19 - "In this
study we investigated, in adult male rats, the effects of the acute
administration of pregnenolone-sulfate (PREGS) (10mg/Kg, s.c.) on cognitive
processes using the Can test, a non aversive spatial/visual task which
allows the assessment of both spatial orientation-acquisition and object
discrimination in a simple and in a complex version of the visual task ...
Our results indicate that, PREGS induces an improvement in spatial
orientation-acquisition and in object discrimination in the simple and in
the complex visual task; the behavioural responses were also confirmed by
electrophysiological recordings showing a potentiation in the neuronal
activity of the hippocampus and the perirhinal cortex" - See
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