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Home > Anti-aging Research > NutraFlora FOS

NutraFlora® FOS (Fructooligosaccharides)

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News & Research:

  • Effect of Dietary Prebiotic Supplementation in Pre-diabetes - Medscape, 10/1/14 - "Thirty adults with pre-diabetes (Impaired Glucose Tolerance or Impaired Fasting Glucose) aged between 40–60 years will be randomly assigned to receive either 10 grams of prebiotic (inulin/oligofructose) daily or 10 grams placebo (maltodextrin) daily for 12 weeks ... Supplementation of the diet with bifidogenic prebiotic fibres (such as inulin) may reduce or retard the accumulation of AGEs in individuals at risk of developing type 2 diabetes. Prebiotics have been shown to improve and restore optimal microbial balance within the gastrointestinal tract, potentially reducing AGE absorption and/or production by the human host. Preliminary investigations indicate that consuming a high-AGE diet is sufficient to favour the proliferation of potentially pathogenic colonic bacteria over more beneficial species. Consumption of glycated proteins,[34] fried meats[61] and toasted wheat flakes[62] encouraged the preferential growth of greater numbers of detrimental gram negative and sulphate-reducing colonic micro-organisms when compared to control diets. Short Chain Fatty Acids (SCFAs) produced as a bacterial by-product of prebiotic fermentation act to lower the intestinal pH, inhibiting the growth of protein-degrading micro-organisms capable of producing potentially toxic metabolites. SCFAs also stimulate colonic smooth muscle contractions, speeding intestinal transit and limiting the time available for protein fermentation and putrefaction to occur in the gut.[63] Therapeutic manipulation of the gut microbiota with prebiotics may restore gut normobiosis and reduce AGE accumulation in humans at risk for type 2 diabetes development by the following mechanisms" - See prebiotic supplements at Amazon.com.
  • Two studies back up FOS efficacy - Nutra USA, 8/27/07
  • Scientific Evidence On FOS Deserves Serious Attention, Nutrition Expert Says - Doctor's Guide, 5/8/97
  • Research Highlights Positive Effects of Dietary Supplement NutraFlora FOS - Doctor's Guide, 12/9/96
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