|Please support this
website by purchasing via the links on the website.
Anti-aging Research > Mucuna Pruriens
News & Research:
Heat-Stable Extract From Mucuna Stimulates the Differentiation of Bone Marrow
Cells Into Dendritic Cells and Induces Apoptosis in Cancer Cells - Nutr
Cancer. 2010 Dec 16:1 - "Pine cone extract is known to
induce differentiation of human mononuclear cells into dendritic cells (DCs) and
also to induce apoptosis in human cancer cells. In the present study, we
screened edible plants that contain components with biological activities
similar to or more potent than those of pine cone extract. We found that Mucuna
(Mucuna pruviens var. utilis) contains a DC differentiation/maturation-inducing
activity and a component that induces apoptosis in human cancer cell lines.
Mucuna extract specifically stimulated differentiation of BM cells to immature
DCs. Marked production of IL-6 was observed by sequential treatment with at
least 10 μg/mL of Mucuna extract followed by LPS. The sequential treatment with
Mucuna extract followed by LPS produced a much higher ratio of IL-12 to IL-6 and
a lower ratio of TNF-α to IL-6 than that obtained by sequential treatment with a
medicinal mushroom Phellinus linteus extract and then LPS. The DC
differentiation/maturation activity and the component inducing apoptosis in
cancer cells were separable by column chromatography" - See
Mucuna pruriens at Amazon.com.
Dendritic cell -
Wikipedia - "Dendritic cells (DCs) are immune
cells that form part of the mammalian immune system. Their main function
is to process antigen material and present it on the surface to other
cells of the immune system, thus functioning as antigen-presenting
cells. They act as messengers between the innate and adaptive immunity"
QualityCounts.com Anti-aging Newsletter
Netvibes basic (free)