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Anti-aging Research > Iodine
Note: I purchased Lugol's Iodine Solution(2 oz.) Twin Pack(2 bot.)
It says nothing about dosage on the bottle and I
was surprised how difficult it was trying to find RELIABLE information
on dosage via Google. Here's the best I could do:
- “LUGOL'S 5%: Each VERTICAL drop is about 6.25 mg's of iodine/potassium
iodide (2.5 mg iodine, 3.75 mg potassium iodide)” - So if the 5% is 2.5
mg of iodine per vertical drop then the 2% would be 1 mg per vertical
drop (2/5 times 2.5 mg = 1 mg).
https://home.comcast.net/~jocy1/junk/The Guide to Supplementing with
(page 4) – “How many milligrams per drop? ... Lugol's 2% = Iodine 1.0 mg
… The iodine doctors are now beginning to believe that 50 mgs may be the
minimum required dose” – Note: They came up with the same mg/drop that I
http://curezone.com/upload/PDF/Assa_Iodine/Anaiodine7.pdf - “Since then,
the collective experience of a large number of clinicians from the US
over the last century has resulted in the recommended daily amount of
0.1 to 0.3 ml of Lugol, containing from 12.5 to 37.5 mg elemental
iodine, for iodine/iodide supplementation” – Note: Most of the articles
seem to quote the author (Guy E. Abraham, MD) and this article, .
The consensus seems to be 50 mg per day (50 drops of the Lugol’s 2%) if
you are deficient and 25 mg per day (25 drops of the Lugol’s 2%) for
maintenance. It would seem prudent to space those drops throughout the
day. You might want to stay on the safe side and go with 12.5 to 37.5 mg
elemental iodine (12 to 37 vertical drops per day of the 2%).
News & Research:
High burden of Iodine deficiency found in Israel’s first national survey
- Science Daily, 3/27/17 - "62% of school-age
children and 85% of pregnant women fall below the WHO's adequacy range ...
According to the researchers, the high burden of iodine insufficiency in
Israel is a serious public health and clinical concern. By comparison to
data from other countries with a similar extent of deficiency, these data
suggest that there is a high risk of maternal and fetal hypothyroidism and
impaired neurological development of the fetus in Israel ... Individuals can
improve their iodine status through increased consumption of iodine-rich
foods such as milk, dairy and salt water fish. They can also replace regular
table salt with iodized salt ... only a small fraction of the salt sold in
Israel is iodized, and it is sold at a much higher price than regular salt,
although it does not need to be" - See Lugol's Iodine Solution(2 oz.) Twin Pack(2 bot.)
Many pregnant women have insufficient iodine; may impair baby's neurological
development - Science Daily, 8/26/15 - "the
median urinary iodine concentration (UIC) in the study group was 98 μg/l,
which is far less that the recommended minimum levels of 150 μg/l"
Iodine deficiency in pregnant women impairs embryonic brain development
- Science Daily, 1/20/15 - "iodine is extremely
important for embryonic brain development. Even a mild iodine deficiency can
impair the child's intellectual development; recent studies in the UK and
Australia have shown that IQs are in fact reduced by a few points ... The
most extreme form of iodine deficiency presents itself in the form of a
condition known as cretinism, which includes metabolic changes, deformities
of the skeleton and underactivity of the thyroid gland"
Iodide protects against dangerous reperfusion injury after heart attack
- Science Daily, 11/7/14 - "When mice with induced
heart attacks were given intravenous infusions of sodium iodide five minutes
before reperfusion, it reduced myocardial infarction, or MI, damage by as
much as 75 percent. And when mice were given sodium iodide in their drinking
water for two days before the procedure, they showed similar significant
protection against the damage ... only iodide boasts a superior safety
profile. Even in large quantities, iodide is very safe, they noted. And it's
already approved for human ingestion -- and widely available. "You can buy
it on Amazon right now," Roth noted"
- Talk to
Pregnant/Nursing Patients About Iodine Supplements - Medscape, 8/11/14 -
"iodine deficiency in the United States is occurring
at least marginally in about one third of pregnant women ... this deficiency
may be compounded by environmental exposures that are ubiquitous: for
example, perchlorate, which may take the place of iodide and thus make
iodide less available for the thyroid and for breastmilk ... One reason for
the deficiency in iodine is the increased consumption in the United States
of processed foods; these don't contain, in general, iodized salt. The
second contributor is that the supplements taken in pregnancy or by
breastfeeding women, as we mentioned before, don't contain adequate amounts
of iodine and are not always labeled correctly ... few supplements contain
adequate amounts of iodine and labeling issues persist"
- Iodine Content of
US Weight-loss Food - Medscape, 6/15/14 - "The
recommended iodine intake is 150 mg/day in adults, 220 µg/day during
pregnancy, and 290 µg/day during lactation. Individuals exclusively
consuming restricted diets as part of a weight-loss program may be at risk
for mild to moderate iodine deficiency ... These results indicate that the
dietary content in the foods from 3 U.S. commercial weight- loss programs is
far less than the recommendations for iodine intake of 150 µg/day in
nonpregnant, nonlactating adults. Individuals following each weight-loss
program should be advised to take a multivitamin containing 150 µg of iodine
daily" - See
iodine at Amazon.com.
- Iodide Supplements
Needed by Pregnant, Nursing Women - Medscape, 5/26/14 -
"Many women of reproductive age in the United States
are marginally iodine deficient, perhaps because the salt in processed foods
is not iodized ... Iodine deficiency, per se, can interfere with normal
brain development in their offspring; in addition, it increases
vulnerability to the effects of certain environmental pollutants, such as
nitrate, thiocyanate, and perchlorate. Although pregnant and lactating women
should take a supplement containing adequate iodide, only about 15% do so"
- Note: I wasn't even aware that the salt in processed food isn't
iodized and I don't use extra salt in my diet. See
iodine at Amazon.com.
- Iodine Deficiency
Still a Concern, Despite Vast Improvements - Medscape, 5/21/13 -
"In the United States, median UIC levels among
individuals aged 6 years and older remained in the normal range, at 144
µg/L, from 2007 to 2010, but median UIC among adults has been on the
decline, with a drop of more than 50% between the 1970s and 1990s, say the
authors ... And the prevalence of UIC below 50 µg/L among women of
childbearing age has increased nearly 4-fold during the same period, from 4%
to 15%, while the median UIC among pregnant US women has declined to less
than 150 µg/L, suggestive of mild iodine deficiency ... The cause of the
decline among pregnant women is unknown but may have to do with reductions
in dairy intake ... only about 70% of salt is iodized, and about 85% of salt
ingested in the United States is from commercially processed foods that do
not contain iodized salt" - See
iodine at Amazon.com. I put a couple drops in my coffee every day.
Mild iodine deficiency in womb associated with lower scores on children's
literacy tests - Science Daily, 4/30/13 -
"Although the participants' diet was fortified with iodine during childhood,
later supplementation was not enough to reverse the impact of the deficiency
during the mother's pregnancy ... inadequate iodine exposure during
pregnancy was associated with lasting effects. As 9-year-olds, the children
who received insufficient iodine in the womb had lower scores on
standardized literacy tests, particularly in spelling. However, inadequate
iodine exposure was not associated with lower scores on math tests" -
See iodine at Amazon.com.
- How Much Iodine Is
Too Much? - Medscape, 1/18/12 - "at relatively
higher doses -- 400 mcg a day and up -- study participants began developing
subclinical hypothyroidism ... people -- at least in China -- should get no
more than 800 mcg a day"
Thyroid Health: How Much Iodine Helps? - WebMD, 6/28/06
- Inadequate Iodine
Intake Linked to Low Intelligence Quotient
- Medscape, 8/9/04 -
"This study demonstrates that the IQ of
schoolchildren in a developed country can be influenced by iodine intake"
Iodine supplements for mothers who smoke? - Nutra USA, 1/29/04
Iodine Deficiency, A Main Cause Of Mental Disabilities, Will Be Eliminated
In Three Years Across The Globe - Intelihealth, 5/9/02 -
"In extreme cases, iodine deficiency can cause goiter
and cretinism, a thyroid deficiency causing arrested mental and physical
deformity. In its milder forms, it ripples across entire societies, with
lesser degrees of mental impairment"
Prognosis Not So Bright For New Breast Disease Drug (Iogen for fibrocystic
breast disease) - Intelihealth, 2/16/01 -
"iodine rids women suffering from FBD of symptoms.
Two unrelated studies, one in Canada and one in Russia, involving nearly
1,500 women, showed iodine reduced the number of cysts and the level of
pain. . . . Iogen contains no iodine, but when it is broken down by the
body, it becomes molecular iodine. And unlike the iodine found in foods,
which is toxic to the thyroid in large quantities, Iogen seems to deliver
large doses of pure iodine without dangerous side effects."
The Importance of Thyroid Supplementation - Life Enhancement Magazine,
Low thyroid levels during pregnancy may lower child's IQ
- CNN, 8/18/99
Are Vegetarians Iodine-Deficient? - Nutrition Science News, 6/99
Iodine Concentrations Associated with Dyslipidemia in US Adults - Nutrients.
2016 Mar 17;8(3) - "Those with the lowest decile of
UIC were more likely to be at risk for elevated total cholesterol (>200 mg/dL)
(adjusted odds ratio (AOR) = 1.51, 95% confidence interval (CI): 1.03-2.23)
and elevated LDL cholesterol (>130 mg/dL) (AOR = 1.58, 95% CI: 1.11-2.23)
and lowered HDL/LDL ratio (<0.4) (AOR = 1.66, 95% CI: 1.18-2.33), compared
to those with UIC above the 10th percentile. In US adults, low UIC was
associated with increased odds for dyslipidemia" - See Lugol's Iodine Solution(2 oz.) Twin Pack(2 bot.)
Supplementation Decreases Hypercholesterolemia in Iodine-Deficient,
Overweight Women: A Randomized Controlled Trial - J Nutr. 2015 Jul 22 -
"Our findings suggest that moderate to severe iodine
deficiency in overweight women elevates serum TSH and produces a more
atherogenic lipid profile and that iodine supplementation in this group
reduces the prevalence of hypercholesterolemia. Thus, iodine prophylaxis may
reduce cardiovascular disease risk in overweight adults"
Iodine-deficiency disorders in the Aseer region, south-western Saudi Arabia:
20 years after the national survey and universal salt iodization -
Public Health Nutr. 2015 Jan 7:1-7 - "The study
documented that 18 years after the national study, and after more than a
decade of universal salt iodization in Saudi Arabia, the problem of
iodine-deficiency disorders is still endemic in the Aseer region"
deficiency in pregnant women in Austria - Eur J Clin Nutr. 2014 Dec 10 -
"In Austria, iodine deficiency has been considered
to be eliminated owing to table salt fortification with iodine, but whether
this also applies to pregnant women is unclear. Even mild iodine deficiency
during gestation may lead to neurocognitive sequelae in the offspring ...
Pregnant women in the Vienna area had a median urinary iodine concentration
(UIC) of 87 μg/l. Only 13.8% of the cohort were in the recommended range of
150-249 μg/l ... doses of 100-150 μg per day are not sufficient to normalize
iodine excretion. Sodium and iodine concentrations in the urine were tightly
correlated (R=0.539, n=61), suggesting that low intake of iodized salt might
contribute to insufficient iodine supply" - Note: I read
somewhere that the salt in processed food isn't iodized. Seems like
the take-away message from this study is that if you're watching your health
by avoiding table salt you're probably going to be deficient in iodine.
iodine at Amazon.com.
Critical Need for Iodine Supplements During Pregnancy and While Nursing
- Science Daily, 12/18/12 - "Iodine levels in the US
have been decreasing, which has the potential to negatively impact the
mother and unborn child ... Iodine, which is not naturally made in the human
body, must be consumed through foods rich in the element or through
supplements. Iodine is required for the production of thyroid hormone, and
adequate thyroid hormone levels are critical for normal fetal
neurodevelopment. National and international health organizations currently
recommend that pregnant women take at least 150 µg of potassium iodide daily
... There is concern that even mild iodine deficiency in pregnant women
could lead to children with lower IQ's"
supplementation improves cognition in mildly iodine-deficient children -
Am J Clin Nutr. 2009 Sep 2 - "The overall cognitive
score of the iodine-supplemented group was 0.19 SDs higher than that of the
placebo group ... Iodine supplementation improved perceptual reasoning in
mildly iodine deficient children and suggests that mild iodine deficiency
could prevent children from attaining their full intellectual potential"
Iodine uptake and loss - can frequent strenuous exercise induce iodine
deficiency? - Horm Metab Res. 2005 Sep;37(9):555-8 -
"Crude calculations reveal that if sweat iodide losses are not replaced,
dietary stores could be depleted in an athlete undergoing a regular training
regime ... iodine loss may have implications for thyroid status and possibly
consequences for athletic performance"
The effects of iodine on intelligence in children: a meta-analysis of
studies conducted in China - Asia Pac J Clin Nutr. 2005;14(1):32-42 -
"The intelligence damage of children exposed to severe ID was profound,
demonstrated by 12.45 IQ points loss"
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