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Anti-aging Research > Glucarate
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Modulation of carcinogen metabolism and DNA interaction by calcium glucarate
in mouse skin - Toxicol Sci. 2004 May;79(1):47-55. Epub 2004 Feb 19 -
"Cag exerted its antitumor effect possibly by inhibiting the carcinogen-DNA
binding, which appears to be due to reduced DNA synthesis and AHH activity"
Detoxifying cancer causing agents to prevent cancer - Integr Cancer
Ther. 2003 Jun;2(2):139-44 -
"There is now growing evidence for the possible
control of different stages of the cancer induction by inhibiting
beta-glucuronidase with D-glucaric acid derivatives, especially with its
salts (D-glucarates) ... the consumption of fruits and vegetables naturally
rich in D-glucaric acid or self-medication with D-glucaric acid derivatives
such as calcium D-glucarate offers a promising cancer prevention approach"
Calcium glucarate prevents tumor formation in mouse skin - Biomed
Environ Sci. 2003 Mar;16(1):9-16 -
"antitumorigenic effect of Cag is considered to be
possibly due to stimulation of differentiation and suppression of
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