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Diabetes

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• neuropathic pain / syndrome X / HbA1c

Popular Medications:

• Actos (pioglitazone HCl) / Amaryl (glimepiride) / Avandia (rosiglitazone) / Byetta (exenatide) / Diabeta, Micronase (glyburide) /  Glucophage (metformin) / insulin / Januvia (sitagliptin) / Lantus (glargine) / Onglyza (saxagliptin) / Prandin™ (repaglinide) / Precose (acarbose) / Rezulin (troglitazone) / Starlix® (nateglinide) / Symlin (pramlintide acetate) / Victoza (liraglutide)

Popular Supplements:

• Alpha lipoic acid / CLA / HCA / PGX / gymnema / vitamin E / ginseng / stevia / magnesium / chromium / fiber / vanadium

Alternative News:

• Really? To Lower Your Risk of Diabetes, Eat Breakfast - NYTimes.com, 4/30/12 - "People who skip that all-important first meal of the day, studies show, suffer setbacks in mood, memory and energy levels. They are also more likely to gain weight, in part because of excess eating later in the day ... researchers followed 29,000 men for 16 years, tracking their diets, exercise, disease rates and other markers of health ... Those who regularly skipped breakfast had a 21 percent higher risk of developing diabetes than those who did not"
• Why Coffee May Reduce Diabetes Risk - WebMD, 1/13/12 - "The Chinese researchers looked at three major active compounds in coffee and their effect on stopping the toxic accumulation of the protein: ... Caffeine ... Caffeic acid or CA ... Chlorogenic acid or CGA ... All three had an effect. However, caffeic acid was best" - Note:  I've always thought that artichoke extract which is 6% chlorogenic acid would do the same thing:
  • Chlorogenic acid - Wikipedia, the free encyclopedia - "Chlorogenic acid is a hydroxycinnamic acid, a member of a family of naturally occurring organic compounds. These are esters of polyphenolic caffeic acid and cyclitol (-)-quinic acid"
• Short Sleep Duration and Poor Sleep Quality Increase the Risk of Diabetes in Japanese Workers With No Family History of Diabetes - Diabetes Care. 2011 Dec 30 - "family history of diabetes (FHD) ... Having diabetes was defined as taking medication for diabetes or a fasting plasma glucose level of ≥126 mg/dL at follow-up (2007-2008) ... after adjustment for potential confounding factors, the odds ratio (95% CI) for developing diabetes was 5.37 (1.38-20.91) in those with a sleep duration of ≤5 h compared with those with a sleep duration of >7 h. Other risk factors were awakening during the night (5.03 [1.43-17.64]), self-perceived insufficient sleep duration (6.76 [2.09-21.87]), and unsatisfactory overall quality of sleep (3.71 [1.37-10.07]). In subjects with an FHD, these associations were either absent or weaker"
• Processed and Unprocessed Red Meat Consumption and Incident Type 2 Diabetes Among French Women - Diabetes Care. 2011 Nov 18 - "Comparing the highest category of processed meat intake, ≥5 servings/week (median, 48 g/day), to the lowest, <1 serving/week (median, 5 g/day), processed meat was significantly associated with incident diabetes (hazard ratio 1.30 [95% CI 1.07-1.59], P trend = 0.0007; for 1 serving/day, 1.29 [1.14-1.45]). Unprocessed red meat was not associated with diabetes"
• Vitamin D could lower risk of developing Type 2 diabetes, study suggests - Science Daily, 10/4/11 - "New tests performed on participants of the KORA study have shown that people with a good supply of vitamin D have a lower risk of developing Type 2 diabetes mellitus, while individuals with lower concentrations of vitamin D in their blood have a higher risk. This effect could be attributable, amongst other things, to the anti-inflammatory effect of vitamin D"
• A Diet High in Low-Fat Dairy Products Lowers Diabetes Risk in Postmenopausal Women - J Nutr. 2011 Sep 21 - "After multivariable adjustment, low-fat dairy product consumption was inversely associated with the risk of type 2 diabetes. RR was roughly 0.5-0.6 in the upper quintiles compared with the lowest quintile (median servings/d, 2.8 in the 5th quintile and 1.5 in the 4th quintile vs. 0.05 in the first quintile; P-trend < 0.001). The inverse relationship was more pronounced in women with a higher BMI. High yogurt consumption was associated with a significant decrease in diabetes risk, whereas there was no relationship between high-fat dairy product consumption and diabetes risk"
• Early research shows dietary supplement may lower risk of developing type 2 diabetes - Science Daily, 9/22/11 - "a naturally produced amino acid-like molecule called GABA was given orally to mice that were obese, insulin resistant and in the early stages of Type 2 diabetes. Researchers found that GABA suppressed the inflammatory immune responses that are involved in the development of this condition ... GABA helped prevent disease progression and improved glucose tolerance and insulin sensitivity, even after onset of Type 2 diabetes in mice" - See GABA products at iHerb.
• Harvard study supports coffee’s anti-diabetes potential - Nutra USA, 9/21/11 - "Five cups of coffee per day for two months were associated with significant metabolic benefits and live function ... the metabolic benefits were more pronounced in caffeinated coffee, a result that supports the hypothesis that caffeine is responsible for some of the apparent benefits ... Coffee is also a rich source of polyphenols ... one cup of the stuff could provide 350 milligrams of phenolics ... Of these, the most abundant compounds in coffee are chlorogenic acids, making up to 12 per cent of the green coffee bean. The most abundant of these compounds is caffeic acid ... recruited 45 healthy, overweight coffee drinking 40 year olds ... volunteers were asked to drink five cups of coffee per day of instant caffeinated coffee, decaffeinated coffee, or water for eight weeks ... coffee consumption was associated with a 60% reduction in blood levels of a compound called interleukin-6, which can promote inflammation, compared with the water group ... In addition, levels of adiponectin – a hormone released from fat cells that plays an important role in the regulation of insulin sensitivity and energy – also decreased in the caffeinated, but not decaffeinated group" - [Abstract]
• High-Protein Diet Raises Type 2 Diabetes Risk - Medscape, 9/13/11 - "The study consisted of 27,140 individuals 45 to 74 years of age who participated in the Malmö Diet and Cancer study ... the researchers found a 37% increased risk for type 2 diabetes associated with high protein intake (hazard ratio [HR], 1.37; 95% confidence interval [CI], 1.17 to 1.61; P for trend < .001]. High intake of processed meat was also associated with an elevated risk for diabetes (HR, 1.17; 95% CI, 1.00 to 1.36; P for trend = .005) ... The intake of breads and cereals rich in fiber was associated with a lower risk of developing diabetes (HR, 0.95; 95% CI, 0.92 to 0.98; P for trend = .005)"
• Magnesium Intake and Risk of Type 2 Diabetes: Meta-analysis of prospective cohort studies - Diabetes Care. 2011 Sep;34(9):2116-2122 - "Meta-analysis of 13 prospective cohort studies involving 536,318 participants and 24,516 cases detected a significant inverse association between magnesium intake and risk of type 2 diabetes (relative risk [RR] 0.78 [95% CI 0.73-0.84]). This association was not substantially modified by geographic region, follow-up length, sex, or family history of type 2 diabetes. A significant inverse association was observed in overweight (BMI ≥25 kg/m(2)) but not in normal-weight individuals (BMI <25 kg/m(2)), although test for interaction was not statistically significant (P(interaction) = 0.13). In the dose-response analysis, the summary RR of type 2 diabetes for every 100 mg/day increment in magnesium intake was 0.86 (95% CI 0.82-0.89)" - See Jarrow Formulas, Magnesium Optimizer Citrate, 100 Easy-Solv Tablets at iHerb.
• Red meat linked to increased risk of type 2 diabetes - Science Daily, 8/10/11 - "After adjusting for age, body mass index (BMI), and other lifestyle and dietary risk factors, the researchers found that a daily 100-gram serving of unprocessed red meat (about the size of a deck of cards) was associated with a 19% increased risk of type 2 diabetes. They also found that one daily serving of half that quantity of processed meat -- 50 grams (for example, one hot dog or sausage or two slices of bacon) -- was associated with a 51% increased risk ... Clearly, the results from this study have huge public health implications given the rising type 2 diabetes epidemic and increasing consumption of red meats worldwide ... for an individual who eats one daily serving of red meat, substituting one serving of nuts per day was associated with a 21% lower risk of type 2 diabetes; substituting low-fat dairy, a 17% lower risk; and substituting whole grains, a 23% lower risk ... consumption of processed red meat -- like hot dogs, bacon, sausage, and deli meats, which generally have high levels of sodium and nitrites -- should be minimized and unprocessed red meat should be reduced. If possible, they add, red meat should be replaced with healthier choices, such as nuts, whole grains, low-fat dairy products, fish, or beans"
• Increased muscle mass may lower risk of pre-diabetes: Study shows building muscle can lower person's risk of insulin resistance - Science Daily, 7/28/11 - "the greater an individual's total muscle mass, the lower the person's risk of having insulin resistance, the major precursor of type 2 diabetes"
• Fish intake and type 2 diabetes in Japanese men and women: the Japan Public Health Center-based Prospective Study - Am J Clin Nutr. 2011 Jul 20 - "During the 5-y period, 971 new cases (572 men and 399 women) of type 2 diabetes were self-reported. In men, fish intake was significantly associated with a decreased risk of type 2 diabetes; multivariable-adjusted ORs of type 2 diabetes for the highest compared with the lowest quartile of intake were 0.73 (95% CI: 0.54, 1.00; P-trend = 0.04) for total fish and seafood and 0.68 (95% CI: 0.50, 0.92; P-trend = 0.016) for small and medium fish (horse mackerel and sardine, saury and mackerel, and eel). Additional analysis by fat content of fish did not detect any significant association for each category. In women, fish intake was not appreciably associated with type 2 diabetes risk" - See Mega Twin EPA at iHerb and Jarrow Max DHA at iHerb.
• Adolescent dairy product consumption and risk of type 2 diabetes in middle-aged women - Am J Clin Nutr. 2011 Jul 13 - "Compared with women in the lowest quintile of high school dairy product intake, those in the highest quintile (2 servings/d) had a 38% lower risk of T2D (RR: 0.62; 95% CI: 0.47, 0.83; P-trend = 0.0006), after adjustment for high school risk factors. After adjustment for adult risk factors, the association persisted (RR: 0.73; 95% CI: 0.54, 0.97; P-trend = 0.02) but was attenuated after adjustment for adult dairy product consumption. In a multivariate joint comparison of dairy product consumption by adults and high school adolescents, compared with women with consistently low intakes, those with consistently high intakes had the lowest risk of T2D (RR: 0.57; 95% CI: 0.39, 0.82) ... Our data suggest that higher dairy product intake during adolescence is associated with a lower risk of T2D. Some of the benefit of dairy product intake during high school may be due to the persistence of the consumption pattern during adulthood"
• Diabetes prevalence is associated with serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D in US middle-aged Caucasian men and women: a cross-sectional analysis within the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial - Br J Nutr. 2011 May 17:1-6 - "Caucasians who had 25(OH)D ≥ 80 nmol/l were half as likely to have diabetes (OR 0.5 (95 % CI 0.3, 0.9)) compared with those who had 25(OH)D < 37 nmol/l. Those in the highest quartile of 1,25(OH)2D ( ≥ 103 pmol/l) were less than half as likely to have diabetes (OR 0.3 (95 % CI 0.1, 0.7)) than those in the lowest quartile ( < 72 pmol/l). In conclusion, the independent associations of 25(OH)D and 1,25(OH)2D with diabetes prevalence in a large population are new findings, and thus warrant confirmation in larger, prospective studies" - See vitamin D products at iHerb.
• Higher Vitamin D Levels Linked to Lower Diabetes Risk - Medscape, 6/25/11 - "The mean follow-up of the 2039-person cohort was 3.2 years ... Participants with vitamin D levels in the highest tertile (median concentration, 30.1 ng/mL) had a hazard ratio of 0.74 (95% confidence interval [CI], 0.59 to 0.93) for developing diabetes, compared with those with vitamin D levels in the lowest tertile (median concentration, 12.8 ng/mL)" - See vitamin D products at iHerb.
• Low Serum Vitamin D Is Associated with High Risk of Diabetes in Korean Adults - J Nutr. 2011 Jun 22 - "Compared to individuals with a sufficient serum 25(OH)D concentration ≥75 nmol/L, the OR (95% CI) for diabetes mellitus were 1.73 (1.09-2.74), 1.30 (0.91-1.84), and 1.40 (0.99-1.98) for serum 25(OH)D concentrations <25, 25 to <50, and 50 to <75 nmol/L, respectively, after multiple adjustments (P-trend < 0.0001). Furthermore, the serum 25(OH)D level was inversely associated with HOMA-IR (β = -0.061; P = 0.001) and positively associated with QUICKI (β = 0.059; P = 0.001) in overweight or obese participants. In conclusion, a low serum vitamin D concentration is associated with a high risk of diabetes mellitus in Korean adults and the concentration is inversely associated with insulin resistance in those who are overweight or obese" - See vitamin D products at iHerb.
• Fish, shellfish, and long-chain n-3 fatty acid consumption and risk of incident type 2 diabetes in middle-aged Chinese men and women - Am J Clin Nutr. 2011 Jun 15 - "Fish, shellfish, and long-chain n-3 fatty acid intakes were inversely associated with T2D in women. The relative risks [RRs (95% CI)] for quintiles of fish intake were 1.00, 0.96 (0.86, 1.06), 0.84 (0.75, 0.94), 0.80 (0.71, 0.90), and 0.89 (0.78, 1.01) (P for trend = 0.003) and for shellfish were 1.00, 0.91 (0.82, 1.01), 0.79 (0.71, 0.89), 0.80 (0.71, 0.91), and 0.86 (0.76, 0.99) (P for trend = 0.006). In men, only the association between shellfish intake and T2D was significant. The RRs (95% CI) for quintiles of fish intake were 1.00, 0.92 (0.75, 1.13), 0.80 (0.65, 1.00), 0.89 (0.72, 1.11), and 0.94 (0.74, 1.17) (P for trend = 0.50) and for shellfish intake were 1.00, 0.93 (0.76, 1.12), 0.70 (0.56, 086), 0.66 (0.53, 0.82), and 0.82 (0.65, 1.02) (P for trend = 0.003)" - See Mega Twin EPA at iHerb and Jarrow Max DHA at iHerb.
• Protective effect of taurine on diabetic rat endothelial dysfunction - Biomed Res. 2011;32(3):187-93 - "Although taurine treatment failed to decrease serum glucose levels, the increased serum malondialdehyde levels in diabetic rats were significantly decreased after taurine treatment. Norepinephrine-induced hyper-contractility as well as acetylcholine-induced, endothelium-dependent hypo-relaxation in diabetes were significantly prevented after taurine treatment. The differences in the expressions of muscarinic M(3) receptor mRNAs were statistically non-significant between groups. Moreover, diabetes-induced up-regulation of eNOS mRNAs was slightly prevented after taurine treatment. These data suggest that taurine acts beneficially against the diabetes-induced vascular dysfunction. Its potential action as a radical scavenger ameliorates the vascular disorders in diabetes" - See taurine products at iHerb.
• Dairy consumption and risk of type 2 diabetes mellitus: a meta-analysis of cohort studies - Eur J Clin Nutr. 2011 May 11 - "A combined RR of 0.86 (95% confidence interval (CI), 0.79-0.92) was revealed on T2DM risk associated to dairy intake, with little evidence of heterogeneity. For subgroup analysis, a combined RR was 0.82 (95% CI, 0.74-0.90), 1.00 (95% CI, 0.89-1.10), 0.95 (95% CI, 0.86-1.05) and 0.83 (95% CI, 0.74-0.93) for the intake of low-fat dairy, high-fat dairy, whole milk and yogurt, respectively. Dose-response analysis showed that T2DM risk could be reduced 5% for total dairy products and 10% for low-fat dairy products. Conclusion: An inverse association of daily intake of dairy products, especially low-fat dairy, with T2DM was revealed, indicating a beneficial effect of dairy consumption in the prevention of T2DM development"
• Serum 25-Hydroxyvitamin D, Calcium Intake, and Risk of Type 2 Diabetes After 5 Years: Results from a national, population-based prospective study (The Australian Diabetes, Obesity and Lifestyle Study) - Diabetes Care. 2011 Mar 23 - "Those who developed diabetes had lower serum 25OHD (mean 58 vs. 65 nmol/L; P < 0.001) and calcium intake (mean 881 vs. 923 mg/day; P = 0.03) compared with those who remained free of diabetes. Each 25 nmol/L increment in serum 25OHD was associated with a 24% reduced risk of diabetes (odds ratio 0.76 [95% CI 0.63-0.92]) after adjusting for age, waist circumference, ethnicity, season, latitude, smoking, physical activity, family history of diabetes, dietary magnesium, hypertension, serum triglycerides, and FPG. Dietary calcium intake was not associated with reduced diabetes risk. Only serum 25OHD was positively and independently associated with HOMA-S at 5 years. CONCLUSIONS Higher serum 25OHD levels, but not higher dietary calcium, were associated with a significantly reduced risk of diabetes in Australian adult men and women" - See vitamin D products at iHerb.
• Mitochondrial dysfunction in the liver of type 2 diabetic Goto-Kakizaki rats: improvement by a combination of nutrients - Br J Nutr. 2011 Mar 22:1-8 - "treatment with a combination of four nutrients, i.e. R-α-lipoic acid, acetyl-l-carnitine, nicotinamide and biotin, just as with pioglitazone, significantly improves glucose tolerance, insulin release, plasma NEFA, skeletal muscle mitochondrial biogenesis and oxidative stress in Goto-Kakizaki (GK) rats ... A 3-month treatment with the four nutrients significantly improved most of these abnormalities in GK rats, and the effects of the nutrient combination were greater than those of pioglitazone for most of these indices. These results suggest that dietary supplementation with nutrients that are thought to influence mitochondrial function may be an effective strategy for improving liver dysfunction in GK diabetic rats"
  • Goto-Kakizaki rat: Definition from Answers.com - "a strain of laboratory rats that have an inherited predisposition to develop diabetes"
• Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients - Br J Nutr. 2011 Mar 9:1-7 - "After an initial general examination (including blood chemistry), nineteen patients enrolled in the 4-week-long double-blind study were randomly assigned into two groups: a resveratrol group receiving oral 2 × 5 mg resveratrol and a control group receiving placebo. Before and after the second and fourth weeks of the trial, insulin resistance/sensitivity, creatinine-normalised ortho-tyrosine level in urine samples (as a measure of oxidative stress), incretin levels and phosphorylated protein kinase B (pAkt):protein kinase B (Akt) ratio in platelets were assessed and statistically analysed. After the fourth week, resveratrol significantly decreased insulin resistance (homeostasis model of assessment for insulin resistance) and urinary ortho-tyrosine excretion, while it increased the pAkt:Akt ratio in platelets. On the other hand, it had no effect on parameters that relate to β-cell function (i.e. homeostasis model of assessment of β-cell function). The present study shows for the first time that resveratrol improves insulin sensitivity in humans, which might be due to a resveratrol-induced decrease in oxidative stress that leads to a more efficient insulin signalling via the Akt pathway" - See resveratrol products at iHerb.
• Influence of magnesium status and magnesium intake on the blood glucose control in patients with type 2 diabetes - Clin Nutr. 2011 Jan 31 - "Magnesium status was influenced by kidney depuration and was altered in patients with type 2 diabetes, and magnesium showed to play an important role in blood glucose control" - See Jarrow Formulas, Magnesium Optimizer Citrate, 100 Easy-Solv Tablets at iHerb.
• Daily consumption of vitamin D- or vitamin D + calcium-fortified yogurt drink improved glycemic control in patients with type 2 diabetes: a randomized clinical trial - Am J Clin Nutr. 2011 Feb 2 - "randomly allocated to 3 groups to consume plain yogurt drink (PY; containing no vitamin D and 150 mg Ca/250 mL), vitamin D-fortified yogurt drink (DY; containing 500 IU vitamin D(3) and 150 mg Ca/250 mL), or vitamin D + calcium-fortified yogurt drink (DCY; containing 500 IU vitamin D(3) and 250 mg Ca/250 mL) twice per day for 12 wk ... Fasting serum glucose (FSG) ... percentage fat mass (FM) ... In both the DY and DCY groups, mean serum 25(OH)D(3) improved (+32.8 ± 28.4 and +28.8 ± 16.1 nmol/L, respectively; P < 0.001 for both), but FSG [-12.9 ± 33.7 mg/dL (P = 0.015) and -9.6 ± 46.9 mg/dL (P = 0.035), respectively], Hb A(1c) [-0.4 ± 1.2% (P < 0.001) and -0.4 ± 1.9% (P < 0.001), respectively], HOMA-IR [-0.6 ± 1.4 (P = 0.001) and -0.6 ± 3.2 (P < 0.001), respectively], waist circumference (-3.6 ± 2.7 and -2.9 ± 3.3, respectively; P < 0.001 for both), and body mass index [in kg/m(2); -0.9 ± 0.6 (P < 0.001) and -0.4 ± 0.7 (P = 0.005), respectively] decreased significantly more than in the PY group. An inverse correlation was observed between changes in serum 25(OH)D(3) and FSG (r = -0.208, P = 0.049), FM (r = -0.219, P = 0.038), and HOMA-IR (r = -0.219, P = 0.005)" - See vitamin D products at iHerb.
• Prediabetes and Prehypertension in Healthy Adults Are Associated With Low Vitamin D Levels - Diabetes Care. 2011 Jan 31 - "The odds ratio for comorbid PreDM and PreHTN in Caucasian men (n = 898) and women (n = 813) was 2.41 (P < 0.0001) with vitamin D levels ≤76.3 versus >76.3 nmol/L after adjusting for age, sex, and BMI. CONCLUSIONS This study strengthens the plausibility that low serum vitamin D levels elevate the risk for early-stage diabetes (PreDM) and hypertension (PreHTN)" - See vitamin D products at iHerb.
• High oolong tea consumption predicts future risk of diabetes among Japanese male workers: a prospective cohort study - Diabet Med. 2011 Jan 18 - "Compared with those not consuming oolong tea, multivariable adjusted hazard ratios for developing diabetes were 1.00 (95% CI 0.67-1.49) for those who drank one cup of oolong tea per day and 1.64 (95% CI 1.11-2.40) for those drinking two or more cups per day ... Long-term consumption of oolong tea may be a predictive marker for new onset diabetes" - Note:  Oolong tea is purported to prevent diabetes.  This is claiming an 64% increased chance of diabetes the way I read it.
  • Antihyperglycemic effect of oolong tea in type 2 diabetes - Diabetes Care. 2003 Jun;26(6):1714-8 - "oolong tea markedly lowered concentrations of plasma glucose (from 229 +/- 53.9 to 162.2 +/- 29.7 mg/dl, P < 0.001) and fructosamine (from 409.9 +/- 96.1 to 323.3 +/- 56.4 micromol/l ... Oolong tea may be an effective adjunct to oral hypoglycemic agents in the treatment of type 2 diabetes"
• Why coffee protects against diabetes - Science Daily, 1/12/11 - "A protein called sex hormone-binding globulin (SHBG) regulates the biological activity of the body's sex hormones, testosterone and estrogen, which have long been thought to play a role in the development of type 2 diabetes. And coffee consumption, it turns out, increases plasma levels of SHBG"
• Coffee consumption is inversely associated with type 2 diabetes in Chinese - Eur J Clin Invest. 2011 Jan 12 - "The prevalence of T2DM was 14·0% and 10·4% in men and women ... coffee intake was inversely associated with T2DM. Habitual coffee drinkers had 38-46% lower risk of T2DM than nondrinkers. Compared to nondrinkers, the adjusted odds ratios (ORs) for T2DM according to subjects with habitual coffee consumption (<1,1-6, ≥ 7 times per week) were 0·77 (0·52-1·13), 0·46 (0·28-0·76) and 0·37 (0·16-0·83), respectively. The decreasing ORs indicate a dose-response effect of coffee consumption on the likelihood of having T2DM (P < 0·001). A similar relationship was also evident in newly diagnosed T2DM (P < 0·05). The adjusted mean fasting glucose levels gradually decreased as the frequency of coffee consumption increased"
• Oral magnesium supplementation reduces insulin resistance in non-diabetic subjects - a double-blind, placebo-controlled, randomized trial - Diabetes Obes Metab. 2010 Nov 18 - "Mg supplementation resulted in a significant improvement of fasting plasma glucose and some ISI compared to placebo. Blood pressure and lipid profile didn't show significant changes. The results provide significant evidence that oral Mg supplementation improves insulin sensitivity even in normomagnesemic, overweight, non-diabetic subjects emphasizing the need for an early optimisation of Mg status to prevent insulin resistance and subsequently type 2 diabetes" - See Jarrow Formulas, Magnesium Optimizer Citrate, 100 Easy-Solv Tablets at iHerb.
• Oral Aloe Vera for Treatment of Diabetes Mellitus and Dyslipidemia - Medscape, 11/16/10 - "Five out of the seven studies that evaluated diabetes endpoints in humans showed significant reductions in fasting blood glucose after treatment with oral aloe vera in patients with diabetes or prediabetes;[21,22,24,25,28] the remaining two studies reported a trend toward decreased blood or plasma glucose concentrations in the aloe-treated groups.[26,27] Significant reductions in HbA1c—up to 22.6% of baseline—were seen in all three studies that evaluated this measure.[22,27,28] One of these studies reported improvements in fructosamine levels,[27] suggesting an improvement in average blood glucose levels over time" - See aloe vera products at iHerb.
• Serum Potassium May Predict Incident Type 2 Diabetes - Medscape, 10/29/10 - "Serum potassium level was inversely associated with the risk for incident diabetes, based on multivariate analyses. Compared with adults who had a high-normal serum potassium level (5.0 - 5.5 mEq/L), those with serum potassium levels less than 4.0 mEq/L, 4.0 to less than 4.5 mEq/L, and 4.5 to less than 5.0 mEq/L had an adjusted HR of incident diabetes of 1.64 (95% confidence interval [CI], 1.29 - 2.08), 1.64 (95% CI, 1.34 - 2.01), and 1.39 (95% CI, 1.14 - 1.71), respectively" - See potassium products at iHerb.
• Vitamin D Deficiency Associated With Diabetic Retinopathy - Medscape, 10/22/10 - "People with diabetes had significantly lower mean 25-hydroxyvitamin D levels than people without diabetes (22.9 vs 30.3 ng/mL; P < .001), according to the poster. People with no eye disease had the highest serum vitamin D levels (mean, 31.9 ng/mL), and those with proliferative retinopathy had the lowest levels (mean, 21.1 ng/mL) ... People who took a daily multivitamin that included vitamin D (n = 102) had a mean serum vitamin D level of 31.1 ng/mL; those who did not take a multivitamin (n = 119) had vitamin D levels averaging only 22.0 ng/mL (P < .001), according to the poster. Dr. Payne noted that even those who took daily multivitamins had a 44% incidence of vitamin D insufficiency" - See vitamin D products at iHerb.
• Eating mostly whole grains, few refined grains linked to lower body fat - Science Daily, 10/20/10 - "People who consume several servings of whole grains per day while limiting daily intake of refined grains appear to have less of a type of fat tissue thought to play a key role in triggering cardiovascular disease and type 2 diabetes ... Visceral Adipose Tissue ... VAT volume was approximately 10 % lower in adults who reported eating three or more daily servings of whole grains and who limited their intake of refined grains to less than one serving per day ... Visceral fat surrounds the intra-abdominal organs while subcutaneous fat is found just beneath the skin ... visceral fat is more closely tied to the development of metabolic syndrome ... participants who consumed, on average, three daily servings of whole grains but continued to eat many refined grains did not demonstrate lower VAT volume"
• Garlic oil may reverse diabetes linked heart disease - Nutra USA, 9/30/10 - "garlic oil supplementation for diabetic rats leads to several alterations at multiple levels in hearts including cardiac contractile functions and structures, myosin chain gene expressions, oxidative stress, and apoptosis and related signaling activities" - [Abstract] - See garlic oil products at iHerb.
• Plasma 25-hydroxyvitamin d concentration and risk of incident type 2 diabetes in women - Diabetes Care. 2010 Sep;33(9):2021-3 - "After adjusting for matching factors and diabetes risk factors, including BMI, higher levels of plasma 25-OHD were associated with a lower risk for type 2 diabetes. The odds ratio for incident type 2 diabetes in the top (median 25-OHD, 33.4 ng/ml) versus the bottom (median 25-OHD, 14.4 ng/ml) quartile was 0.52 (95% CI 0.33-0.83). The associations were consistent across subgroups of baseline BMI, age, and calcium intake" - See vitamin D products at iHerb.
• Magnesium Intake in Relation to Systemic Inflammation, Insulin Resistance, and the Incidence of Diabetes - Diabetes Care. 2010 Aug 31 - "During 20-year follow-up, 330 incident diabetic cases were identified. Magnesium intake was inversely associated with incidence of diabetes after adjustment for potential confounders. The multivariable-adjusted hazard ratio of diabetes for participants in the highest quintile of magnesium intake was 0.53 (95% confidence interval, 0.32-0.86; P(trend)<0.01) compared with those in the lowest quintile. Consistently, magnesium intake was significantly inversely associated with hs-CRP, IL-6, fibrinogen, and HOMA-IR; and serum magnesium levels were inversely correlated with hs-CRP and HOMA-IR" - See Jarrow Formulas, Magnesium Optimizer Citrate, 100 Easy-Solv Tablets at iHerb.
• Why fish oils work swimmingly against inflammation and diabetes - Science Daily, 9/2/10 - "Researchers at the University of California, San Diego School of Medicine have identified the molecular mechanism that makes omega-3 fatty acids so effective in reducing chronic inflammation and insulin resistance ... omega-3 fatty acids activate this macrophage receptor, resulting in broad anti-inflammatory effects and improved systemic insulin sensitivity ... It's just an incredibly potent effect ... omega-3 fatty acids switch on the receptor, killing the inflammatory response" - See Mega Twin EPA at iHerb and Jarrow Max DHA at iHerb.
• Fruit and vegetable intake and incidence of type 2 diabetes mellitus: systematic review and meta-analysis - BMJ. 2010 Aug 18;341:c4229 - "greater intake of green leafy vegetables was associated with a 14% (hazard ratio 0.86, 95% confidence interval 0.77 to 0.97) reduction in risk of type 2 diabetes (P=0.01). The summary estimates showed no significant benefits of increasing the consumption of vegetables, fruit, or fruit and vegetables combined"
• Sugar Sweetened Beverages and Risk of Metabolic Syndrome and Type 2 Diabetes: A Meta-analysis - Diabetes Care. 2010 Aug - "sugar-sweetened beverages (SSBs), which include soft drinks, fruit drinks, iced tea, energy and vitamin water drinks ... Based on data from these studies, including 310,819 participants and 15,043 cases of T2DM, individuals in the highest quantile of SSB intake (most often 1-2 servings/day) had a 26% greater risk of developing T2DM than those in the lowest quantile (none or < 1 serving/month) (RR:1.26 (95% CI: 1.12, 1.41)). Among studies evaluating MetSyn, including 19,431 participants and 5,803 cases, the pooled RR was 1.20 (95% CI: 1.02, 1.42)"
• Interactions of dietary whole grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies - Diabetes Care. 2010 Aug 6 - "Greater whole grain food intake was associated with lower fasting glucose and insulin concentrations independent of demographics, other dietary and lifestyle factors, and BMI (beta [95% CI] per 1-serving greater whole grain intake: -0.009 mmol/L glucose [-0.013, -0.005], p <0.0001 and -0.011 pmol/L (ln) insulin [-0.015, -0.007], p =0.0003) ... Our results support the favorable association of whole grain intake with fasting glucose and insulin and suggest potential interaction between variation in GCKR and whole grain intake in influencing fasting insulin concentrations"
• Carbohydrate quantity and quality and risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition-Netherlands (EPIC-NL) study - Am J Clin Nutr. 2010 Aug 4 - "glycemic load (GL), glycemic index (GI) ... During a mean follow-up of 10 y, 915 incident diabetes cases were documented. Dietary GL was associated with an increased diabetes risk after adjustment for age, sex, established diabetes risk factors, and dietary factors [hazard ratio (HR) per SD increase: 1.32; 95% CI: 1.14, 1.54; P lt 0.001]. GI tended to increase diabetes risk (HR: 1.08; 95% CI: 1.00, 1.17; P equals 0.05). Dietary fiber was inversely associated with diabetes risk (HR: 0.92; 95% CI: 0.85, 0.99; P lt 0.05), whereas carbohydrate intake was associated with increased diabetes risk (HR: 1.15; 95% CI: 1.01, 1.32; P lt 0.05). Of the carbohydrate subtypes, only starch was related to increased diabetes risk [HR: 1.25 (1.07, 1.46), P lt 0.05]. All associations became slightly stronger after exclusion of energy misreporters. CONCLUSIONS: Diets high in GL, GI, and starch and low in fiber were associated with an increased diabetes risk. Both carbohydrate quantity and quality seem to be important factors in diabetes prevention. Energy misreporting contributed to a slight attenuation of associations"
• Reduction of Postprandial Glycemia by the Novel Viscous Polysaccharide PGX, in a Dose-Dependent Manner, Independent of Food Form - J Am Coll Nutr. 2010 Apr;29(2):92-8 - "The objective of the study therefore was to determine palatability and effectiveness of escalating doses of PGX, a novel viscous polysaccharide (NVP), in reducing postprandial glycemia when added to a liquid and a solid meal ... Addition of NVP to the meal reduced blood glucose incremental areas under the curve irrespective of dose, reaching significance at the 7.5 g dose when added to glucose (p < 0.01), and at the 5 and 7.5 g doses when added to WB + Marg (p < 0.001). The GI values of glucose with 0, 2.5, 5, or 7.5 g of NVP were (mean +/- standard error of the mean [SEM]) 100.0 +/- 0.0, 83.7 +/- 9.0, 77.7 +/- 8.2, and 72.5 +/- 5.9, respectively; the GI of the WB alone, or of WB + Marg, with 0, 2.5, 5, or 7.5 g of NVP was 71.0 +/- 0.0, 66.8 +/- 3.0, 47.5 +/- 5.9, 37.3 +/- 5.9, and 33.9 +/- 3.6, respectively. CONCLUSION: Addition of NVP to different food matrices is highly effective in lowering the glycemic index of a food in a dose-responsive manner" - See Natural Factors, WellBetX PGX with Mulberry, 180 Capsules at iHerb.
• Magnesium Intake and Risk of Self-Reported Type 2 Diabetes among Japanese - J Am Coll Nutr. 2010 Apr;29(2):99-106 - "Dietary intake of magnesium was inversely associated with age- and body mass index (BMI)-adjusted diabetes incidence in both sexes. In multivariable analysis that adjusted further for cardiovascular risk factors, the association was weakened in both sexes, but the association in total participants remained statistically significant. The odds ratios of diabetes with reference to the lowest quartile of magnesium intake were 0.83 (95% confidence interval [CI], 0.69 to 1.09) for the second quartile, 0.79 (95% CI, 0.59 to 1.07) for the third quartile, and 0.64 (95% CI, 0.44 to 0.94) for the highest quartile of magnesium intake (p for trend = 0.04). CONCLUSIONS: Dietary intake of magnesium was associated with a reduced risk of type 2 diabetes in Japanese populations" - See Jarrow Formulas, Magnesium Optimizer Citrate, 100 Easy-Solv Tablets at iHerb.
• First human trial backs GS diabetes benefits - Nutra USA, 7/22/10 - "Their findings recorded an average reduction in fasting blood glucose from 162 ± 23 to 119 ± 17 mg/dL. After eating, blood glucose levels were found to have reduced from 291 ±10 to 236 ±30 mg/dL" - See gymnema products at iHerb.
• Vitamin D levels and mortality in type 2 diabetes - Diabetes Care. 2010 Jul 6 - "All-cause mortality was increased in patients with severe vitamin D deficiency; HR [95% CI] 1.96 [1.29-2.98] ... Severe vitamin D deficiency was associated with increased cardiovascular mortality; HR 1.95 [1.11-3.44]" - See vitamin D products at iHerb.
• Hemoglobin A1c between 5.7 and 6.4% as a marker for identifying pre-diabetes, insulin sensitivity and secretion, and cardiovascular risk factors: The Insulin Resistance Atherosclerosis Study (IRAS) - Diabetes Care. 2010 Jun 23 - "impaired glucose tolerance (IGT) ... impaired fasting glucose (IFG) ... A1C(5.7-6.4%) is less sensitive for detecting at-risk individuals than IFG and IGT, particularly among non-Hispanic whites. Single determinations of FPG and 2-h PG appear more precise correlates of insulin resistance and secretion than A1C and in general better for other metabolic disorders"
• Poor control of diabetes may be linked to low vitamin D - Science Daily, 6/21/10 - "Despite receiving regular primary care visits before referral to the endocrine clinic, 91 percent of patients had either vitamin D deficiency (defined as a level below 15 nanograms per deciliter, or ng/dL) or insufficiency (15 to 31 ng/dL) ... Additionally, the investigators found an inverse relationship between the patients' blood levels of vitamin D and their hemoglobin A1c value, a measure of blood sugar control over the past several months. Lower vitamin D levels were discovered in patients with higher average blood sugars as measured by HbA1c" - See vitamin D products at iHerb.
• Replacing white rice with brown rice or other whole grains may reduce diabetes risk - Science Daily, 6/14/10 - "replacing 50 grams of white rice (just one third of a typical daily serving) with the same amount of brown rice would lower risk of type 2 diabetes by 16%. The same replacement with other whole grains, such as whole wheat and barley, was associated with a 36% reduced risk" - See Lundberg, Organic Brown Rice Pasta, Penne, 12 oz (340 g) at iHerb.
• Do high ferritin levels confer lower cardiovascular risk in men with Type 2 diabetes? - Diabet Med. 2010 Apr;27(4):417-22 - "were divided according to ferritin quartiles (Q) as follows: QI-III, normal ferritin (NF; n = 318), mean +/- 1 sd ferritin 133 +/- 72 ng/ml; and QIV patients, high ferritin (HF; n = 106), ferritin 480 +/- 228 ng/ml ... the prevalence of macroangiopathy was unexpectedly much lower in patients with high ferritin, as follows: 25% vs. 43% for overall macroangiopathy; 7% vs. 16% for peripheral artery disease; and 16% vs. 31% for coronary artery disease (P = 0.0009, P = 0.0140 and P = 0.0035, respectively, vs. NF patients). Insulin resistance index and prevalence of liver steatosis were higher in HF compared with NF patients as follows: 2.17% vs. 1.89% and 78% vs. 64% (P = 0.0345 and P = 0.0059, respectively). Liver enzymes (aspartate aminotransferase, alanine aminotransferase and gamma-glutamyl transferase) were significantly higher in HF, by 33%, 42% and 72%, respectively (all P < 0.0002), suggesting a higher prevalence of steatohepatitis ... Our results demonstrate that T2DM males with high ferritin levels exhibit a markedly decreased prevalence of macroangiopathy, despite more severe insulin resistance and higher markers of steatohepatitis. High ferritin levels and/or steatosis may thus paradoxically confer a lowered cardiovascular risk in diabetic males" - See Slow Fe Slow Release Iron Tablets 90-Count Box at Amazon.com.
• Treatment of gum disease may lower blood sugar levels in type 2 diabetes - Science Daily, 5/12/10 - "Current belief is that, when bacteria infect the mouth and cause inflammation, the resulting chemical changes reduce the effectiveness of insulin produced in the body, thus making it more difficult for diabetics to control their blood sugar"
• New evidence that drinking coffee may reduce the risk of diabetes - Science Daily, 6/9/10 - "The scientists fed either water or coffee to a group of laboratory mice commonly used to study diabetes. Coffee consumption prevented the development of high-blood sugar and also improved insulin sensitivity in the mice, thereby reducing the risk of diabetes. Coffee also caused a cascade of other beneficial changes in the fatty liver and inflammatory adipocytokines related to a reduced diabetes risk. Additional lab studies showed that caffeine may be "one of the most effective anti-diabetic compounds in coffee,""
• Grapes reduce risk factors for heart disease and diabetes, animal study shows - Science Daily, 5/10/10 - "After three months, the rats that received the grape-enriched diet had lower blood pressure, better heart function, and reduced indicators of inflammation in the heart and the blood than rats who received no grape powder. Rats also had lower triglycerides and improved glucose tolerance" - See Jarrow Formulas, OPCs + 95, 100 mg, 100 Capsules.
• Whole Grains Take a Bite Out of Type 2 Diabetes Risk - US News and World Report, 3/25/10 - "people who ate five or more servings per week of white rice were 17 percent more likely to develop type 2 diabetes than those who ate less than one serving of white rice per month ... people who ate two or more servings of brown rice per week were 11 percent less likely to develop type 2 diabetes than those who ate less than one serving of brown rice per month ... We estimated that replacing 50 grams/day intake of white rice with the same amount of brown rice was associated with a 16 percent lower risk of type 2 diabetes, whereas the same replacement with whole grains as a group was associated with a 36 percent lower diabetes risk"
• Selenium protects men against diabetes, study suggests - Science Daily, 3/17/10 - "The role of selenium in diabetes has been controversial, with some studies suggesting that it raises diabetes risk and others finding that it is protective. Now, research published in BioMed Central's open access journal Nutrition and Metabolism, has shown that, for men, high plasma selenium concentrations are associated with a lower occurrence of dysglycemia ... for French elderly males, having plasma selenium concentrations in the top tertile of the population distribution (1.19-1.97 μmol/L) was significantly associated with a lower risk of developing dysglycemia over the following nine years ... The reason we observed a protective effect of selenium in men but not in women is not completely clear, but might be attributed to women being healthier at baseline, having better antioxidant status in general and possible differences in how men and women process selenium" - [Nutra USA] - See selenium products at iHerb.
• Curcumin improves insulin resistance in skeletal muscle of rats - Nutr Metab Cardiovasc Dis. 2010 Mar 12 - "Curcumin improves muscular insulin resistance by increasing oxidation of fatty acid and glucose, which is, at least in part, mediated through LKB1-AMPK pathway" - See curcumin/turmeric products at iHerb.Curcumin improves insulin resistance in skeletal muscle of rats - Nutr Metab Cardiovasc Dis. 2010 Mar 12 - "Curcumin improves muscular insulin resistance by increasing oxidation of fatty acid and glucose, which is, at least in part, mediated through LKB1-AMPK pathway" - See curcumin/turmeric products at iHerb.
• Coffee consumption and the incidence of type 2 diabetes in men and women with normal glucose tolerance: The Strong Heart Study - Nutr Metab Cardiovasc Dis. 2010 Feb 17 - "Compared to those who did not drink coffee, participants who drank 12 or more cups of coffee daily had 67% less risk of developing diabetes during the follow-up (hazard ratio: 0.33, 95% confidence interval: 0.13, 0.81)"
• High levels of vitamin D in older people can reduce heart disease and diabetes - Science Daily, 2/16/10 - "Researchers looked at 28 studies including 99,745 participants across a variety of ethnic groups including men and women. The studies revealed a significant association between high levels of vitamin D and a decreased risk of developing cardiovascular disease (33% compared to low levels of vitamin D), type 2 diabetes (55% reduction) and metabolic syndrome (51% reduction)" - See vitamin D products at iHerb.
• Dietary Anthocyanin-Rich Bilberry Extract Ameliorates Hyperglycemia and Insulin Sensitivity via Activation of AMP-Activated Protein Kinase in Diabetic Mice - J Nutr. 2010 Jan 20 - "Blueberries or bilberries contain large amounts of anthocyanins, making them one of the richest sources of dietary anthocyanin ... bilberry extract (BBE) ... Dietary BBE significantly reduced the blood glucose concentration and enhanced insulin sensitivity ... These findings provide a biochemical basis for the use of bilberry fruits and have important implications for the prevention and treatment of type 2 diabetes via activation of AMPK" - See bilberry products at iHerb.
• Examination of the Antiglycemic Properties of Vinegar in Healthy Adults - Ann Nutr Metab. 2010 Jan 4;56(1):74-79 - "Vinegar reduces postprandial glycemia (PPG) in healthy adults ... Two teaspoons of vinegar ( approximately 10 g) effectively reduced PPG, and this effect was most pronounced when vinegar was ingested during mealtime as compared to 5 h before the meal ... The antiglycemic properties of vinegar are evident when small amounts of vinegar are ingested with meals composed of complex carbohydrates. In these situations, vinegar attenuated PPG by approximately 20% compared to placebo" - See Source Naturals, Apple Cider Vinegar - 1 Source Natural 500 mg tablet equals 2 tsb of vinegar.  4.5 tablets equals about 3 tablespoons by my calculations.
• Alpha-lipoic acid improves vascular endothelial function in patients with type 2 diabetes: a placebo-controlled randomized trial - Eur J Clin Invest. 2009 Dec 27 - "600 mg alpha-lipoic acid or placebo. Results FBF responses were comparable at baseline. After treatment, FBF reactivity to ACh and GTN was unchanged in subjects receiving placebo. By contrast, ALA treatment increased endothelium-dependent vasodilatation to ACh (P < 0.05) but not to GTN compared with baseline. Conclusions Intravenous ALA treatment improves endothelium-dependent vasodilatation in patients with type 2 diabetes, in the absence of effects on forearm vasomotor function. If this salutary action translates into vascular risk reduction remains to be established" - See alpha lipoic acid products at iHerb.
• Quality of HDL Differs in Diabetics But Improves With Niacin Therapy - Medscape, 12/22/09 - "HDL cholesterol in individuals with diabetes has impaired endothelial protective functions compared with the HDL from healthy subjects, although treatment with extended-release niacin can improve these endothelial protective effects" - See Twinlab niacin 1000mg at iHerb.
• Coffee, Tea May Stall Diabetes - WebMD, 12/14/09 - "researchers found each additional cup of coffee drunk per day was associated with a 7% lower risk of diabetes. People who drank three to four cups per day had about a 25% lower risk than those who drank two or fewer cups per day ... The study also showed that people who drank more than three to four cups of decaffeinated coffee per day had about a one-third lower risk of developing type 2 diabetes than those who didn’t drink any ... Tea drinkers who drank more than three to four cups of tea per day had about a one-fifth lower risk of diabetes than those who didn’t drink tea" - [Science Daily] - See Jarrow green tea extract at iHerb.
• Pine bark extract may boost diabetic eye health - Nutra USA, 12/3/09 - "At the end of the study, 75 per cent of participants in the Pycnogenol group subjectively perceived improvements in their visual acuity. Tests showed a significant improvement in visual acuity from 14/20 to 17/20 after two months of Pycnogenol supplementations. No improvements were recorded in the placebo group" -  [Abstract] - See Pine Bark/Pycnogenol products at iHerb or OPC + 95 products at iHerb (some say that the grapeseed extract is the same thing without the patent markup).
• Pycnogenol((R)) Improves Microcirculation, Retinal Edema and Visual Acuity in Early Diabetic Retinopathy - J Ocul Pharmacol Ther. 2009 Nov 16 - "Results: The major positive observation of this study is the visual improvement, which was subjectively perceived by 18 out of 24 patients in the Pycnogenol group. Testing of visual acuity using the Snellen chart showed a significant improvement from baseline 14/20 to 17/20 already, after 2 months treatment, whereas no change was found in the control group. Conclusions: Pycnogenol taken at this early stage of retinopathy may enhance retinal blood circulation accompanied by regression of edema, which favorably improves vision of patients" - See Pine Bark/Pycnogenol products at iHerb or OPC + 95 products at iHerb (some say that the grapeseed extract is the same thing without the patent markup).
• Folic acid shows benefits for diabetic heart health - Nutra USA, 11/2/09 - "diabetic mice fed a daily folic acid supplement equivalent to 5 milligrams per day for a 70 kg human, led to a reversal in the dysfunction occurring in the lining of blood vessels (endothelial dysfunction), compared to a lower dose of the micronutrient" - See folic acid products at iHerb.
• Vitamin D supplements show anti-diabetes potential - Nutra USA, 10/27/09 - "At the end of the test period, women in the vitamin D group experienced “significant improvements” in both insulin sensitivity and resistance, said the researchers, which was also accompanied a decrease in fasting insulin levels, compared to placebo" - [Abstract] - See vitamin D products at iHerb.
• Vitamin D supplementation reduces insulin resistance in South Asian women living in New Zealand who are insulin resistant and vitamin D deficient - a randomised, placebo-controlled trial - Br J Nutr. 2009 Sep 28:1-7 - "In conclusion, improving vitamin D status in insulin resistant women resulted in improved IR and sensitivity, but no change in insulin secretion. Optimal vitamin D concentrations for reducing IR were shown to be 80-119 nmol/l, providing further evidence for an increase in the recommended adequate levels" - See vitamin D products at iHerb.
• 'Red Wine' Chemical May One Day Treat Diabetes - WebMD, 10/9/09 - "Resveratrol, found in red wine, was found to lower blood sugar levels and improve insulin levels when injected directly into the brains of mice fed very high-calorie diets in a study conducted by researchers at the University of Texas Southwestern Medical Center (UTSW) ... resveratrol does not cross the blood-brain barrier very efficiently" - See Jarrow Resveratrol 100 at iHerb.
• Future Diabetes Treatment May Use Resveratrol To Target The Brain - Science Daily, 10/6/09 - "the brain plays a key role in mediating resveratrol's anti-diabetic actions, potentially paving the way for future orally-delivered diabetes medications that target the brain ... Resveratrol activates sirtuins, a class of proteins that are thought to underlie many of the beneficial effects of calorie restriction" - See Jarrow Resveratrol 100 at iHerb.
• How Soy Reduces Diabetes Risk - Science Daily, 10/6/09 - "They found that daidzein and equol enhanced adipocyte differentiation, or the formation of fat cells, through activation of a key transcription regulator, the same receptor that mediates the insulin-sensitizing effects of anti-diabetes drugs. Thus, daidzein and equol daidzein and equol seem to work in a similar manner as anti-diabetic drugs currently in the market"
• Coffee and tea consumption and risk of type 2 diabetes - Diabetologia. 2009 Sep 1 - "After adjustment for potential confounders, coffee and tea consumption were both inversely associated with type 2 diabetes, with hazard ratios of 0.77 (95% CI 0.63-0.95) for 4.1-6.0 cups of coffee per day (p for trend = 0.033) and 0.63 (95% CI: 0.47-0.86) for >5.0 cups of tea per day (p for trend = 0.002). Total daily consumption of at least three cups of coffee and/or tea reduced the risk of type 2 diabetes by approximately 42%"
• Why Low Vitamin D Raises Heart Disease Risks In Diabetics - Science Daily, 8/21/09 - "Low levels of vitamin D are known to nearly double the risk of cardiovascular disease in patients with diabetes ... When people are deficient in vitamin D, the macrophage cells eat more cholesterol, and they can't get rid of it. The macrophages get clogged with cholesterol and become what scientists call foam cells, which are one of the earliest markers of atherosclerosis" - See vitamin D products at iHerb.
• Carnitine Supplements Reverse Glucose Intolerance In Animals - Science Daily, 8/17/09 - "After just eight weeks of supplementation with carnitine, the obese rats restored their cells' fuel- burning capacity (which was shut down by a lack of natural carnitine) and improved their glucose tolerance, a health outcome that indicates a lower risk of diabetes ... These results offer hope for a new therapeutic option for people with glucose intolerance, older people, people with kidney disease, and those with type 2 diabetes (what used to be called adult-onset diabetes) ... Carnitine is a natural compound known for helping fatty acids enter the mitochondria, the powerhouses of cells, where fatty acids are "burned" to give cells energy for their various tasks. Carnitine also helps move excess fuel from cells into the circulating blood, which then redistributes this energy source to needier organs or to the kidneys for removal" - See l-carnitine products at iHerb.
• Resveratrol prevents hyperglycemia-induced endothelial dysfunction via activation of adenosine monophosphate-activated protein kinase - Biochem Biophys Res Commun. 2009 Aug 7 - "Endothelial dysfunction secondary to persistent hyperglycemia plays a key role in the development of type 2 diabetic vascular disease ... These results provide new insight into the protective properties of resveratrol against endothelial dysfunction caused by high glucose, which is attributed to the AMPK mediated reduction of superoxide level" - Click here for a definition of endothelial dysfunction.  See Jarrow Resveratrol 100 at iHerb.
• Effects of grape seed extract in Type 2 diabetic subjects at high cardiovascular risk: a double blind randomized placebo controlled trial examining metabolic markers, vascular tone, inflammation, oxidative stress and insulin sensitivity - Diabet Med. 2009 May;26(5):526-31 - "GSE significantly improved markers of inflammation and glycaemia and a sole marker of oxidative stress in obese Type 2 diabetic subjects at high risk of cardiovascular events over a 4-week period, which suggests it may have a therapeutic role in decreasing cardiovascular risk" - See OPC + 95 products at iHerb.
• Stopping Diabetes Damage With Vitamin C - Science Daily, 6/10/09 - "While neither therapy produced desired results when used alone, the combination of insulin to control blood sugar together with the use of Vitamin C, stopped blood vessel damage caused by the disease in patients with poor glucose control" - See vitamin C products at iHerb.
• Long And Short Sleep Durations Are Associated With Increased Risk For Diabetes - Science Daily, 6/8/09 - "the adjusted odds ratio was 1.24 for diabetes associated with short sleep (five hours per night or less) and 1.48 for diabetes associated with long sleep (nine or more hours per night)"
• CoQ10 Improves Endothelial Dysfunction in Statin-Treated Type 2 Diabetics - Medscape, 5/29/09 - "Study subjects were randomized to receive either 200 mg/day of oral CoQ10 or placebo for 12 weeks ... Our absolute improvement in FMD of 1% with CoQ10 supplementation may potentially translate to a 10-25% reduction in residual cardiovascular risk in these patients" - See coenzyme Q10 products at iHerb.
• Omega Fatty Acid Balance Can Alter Immunity And Gene Expression - Science Daily, 5/29/09 - "Anthropological evidence suggests that human ancestors maintained a 2:1 w6/w3 ratio for much of history, but in Western countries today the ratio has spiked to as high as 10:1. Since these omega fatty acids can be converted into inflammatory molecules, this dietary change is believed to also disrupt the proper balance of pro- and anti- inflammatory agents, resulting in increased systemic inflammation and a higher incidence of problems including asthma, allergies, diabetes, and arthritis ... many key signaling genes that promote inflammation were markedly reduced compared to a normal diet, including a signaling gene for a protein called PI3K, a critical early step in autoimmune and allergic inflammation responses" - See Mega Twin EPA at iHerb and Jarrow Max DHA at iHerb.
• Tea For The Treatment Of Type-2 Diabetes - Science Daily, 5/5/09 - "The research subjects drank 750ml of tea each day. The cure appears to differentiate itself from other current type-2 diabetes treatments because the tea does not initially affect the sugar content of the blood. But after four months of treatment with tea we can, however, see a significant increase in glucose tolerance ... 'n the patient group who drank the tea, the number of polyunsaturated fatty acids increased. That is good for the body's cells because the polyunsaturated fat causes the cell membranes to be more permeable, which results in the cells absorbing glucose better from the blood" - See Jarrow green tea extract at iHerb.
• Recipe for Diabetes: Too Much Protein, Fat - WebMD, 4/7/09 - "A high-fat diet may lead to insulin resistance, a major step on the path to type 2 diabetes. But cutting back on fat may not help those who continue to eat too much protein"
• Diabetics On High-fiber Diets Might Need Extra Calcium - Science Daily, 3/24/09 - "Our new findings suggest that dietary fiber reduces the body's capacity to absorb calcium"
• Consuming A Little Less Salt Could Mean Fewer Deaths - Science Daily, 3/11/09 - "Participants who slept on average less than six hours a night during the work week, when followed over six years, were 4.56 times more likely than those getting six to eight hours of sleep to convert from normal blood sugar levels to impaired fasting glucose"
• Low Vitamin D Hurts Teenagers’ Hearts - WebMD, 3/11/09 - "Compared to the 25% of teens with the highest levels of vitamin D in their blood (more than 26 nanograms per milliliter), the 25% of teens with the lowest vitamin D levels (less than 15 ng/mL) had: ... Fourfold greater risk of metabolic syndrome, a combination of risk factors for diabetes ... 2.54 times greater risk of high blood sugar ... 2.36 times greater risk of high blood pressure" - See vitamin D products at iHerb.
• Brief, Rigorous Exercise Cuts Diabetes Risk - WebMD, 1/27/09 - "doing a few intense muscle exercises, each lasting only about 30 seconds, dramatically improves your metabolism in just two weeks"
• Low Glycemic Diets Help Diabetics Control Blood Sugar, Review Suggests - Science Daily, 1/2/0/09 - "Clinicians measured hemoglobin A1c levels, which give a picture of a person's blood glucose control over several weeks or months. The reviewers found that levels decreased by 0.5 percent with a low GI diet, noting that the findings were significant, both statistically and clinically"
• Plasma 25-Hydroxyvitamin D Is Associated with Markers of the Insulin Resistant Phenotype in Nondiabetic Adults - J Nutr. 2008 Dec 23 - "Among adults without diabetes, vitamin D status was inversely associated with surrogate fasting measures of insulin resistance. These results suggest that vitamin D status may be an important determinant for type 2 diabetes mellitus" - See Vitamin D products at iHerb.
• Treating Gum Disease Linked To Lower Medical Costs For Patients With Diabetes - Science Daily, 12/23/08 - "treating gum disease in patients who have diabetes with procedures such as cleanings and periodontal scaling is linked to 10 to 12 percent lower medical costs per month"
• Low-glycemic Diet Shows Greater Improvement In Glycemic Control Than High-fiber Diet - Science Daily, 12/16/08
• Low-Glycemic Index Diet for Diabetes - WebMD, 12/16/08
• Nearly Three-quarters Of Youths With Diabetes Insufficient In Vitamin D - Science Daily, 12/15/08 - "Three-quarters of youths with type 1 diabetes were found to have insufficient levels of vitamin D, according to a study by researchers at the Joslin Diabetes Center – findings that suggest children with the disease may need vitamin D supplementation to prevent bone fragility later in life" - See vitamin D products at iHerb.
• Ferritin Levels Linked With Risk of Diabetes, Metabolic Syndrome - Medscape, 12/22/08 - "Elevated circulating ferritin concentrations are independently associated with an increased risk of type 2 diabetes and the metabolic syndrome in middle-aged and elderly Chinese subjects ... Men and women had median ferritin concentrations of 155.7 ng/mL and 111.9 ng/mL, respectively (p < 0.001). Compared to patients in the lowest ferritin quartile, those in the highest quartile had substantially higher odds ratios for metabolic syndrome (2.80) and diabetes (3.26)" - Iron supplements has been controversial for years.  I started taking it again because my ferritin was 11.9.
• Vitamin B1 Could Reverse Early-stage Kidney Disease In Diabetes Patients - Science Daily, 12/8/08 - "the team show 300 mg of thiamine taken orally each day for three months reduced the rate of albumin excretion in type 2 diabetes patients. The albumin excretion rate was decreased by 41% from the value at the start of the study. The results also showed 35% of patients with microalbuminuria saw a return to normal urinary albumin excretion after being treated with thiamine .... were randomly assigned a placebo or 3 x 100mg tablets of thiamine a day for three months"
• Vitamin E Shows Possible Promise In Easing Chronic Inflammation - Science Daily, 12/4/08 - "the larger take-home message of the study, published in the December issue of the journal Experimental Physiology, is that Vitamin E “may be beneficial in individuals with chronic inflammation, such as the elderly or patients with type II diabetes or chronic heart failure" - See Jarrow FamilE (contains all eight members of the vitamin E family) at iHerb.
• Potassium Loss From Blood Pressure Drugs May Explain Higher Risk Of Adult Diabetes - Science Daily, 11/24/08 - "a drop in blood potassium levels caused by diuretics commonly prescribed for high blood pressure could be the reason why people on those drugs are at risk for developing type 2 diabetes" - See potassium products at iHerb.
• Green Tea May Delay Onset Of Type 1 Diabetes - Science Daily, 10/23/08 - "EGCG modulates several important genes, so it suppresses the abnormality at the molecular level in the salivary gland. It also significantly lowered the serum autoantibodies, reducing the severity of Sjogren's syndrome-like symptoms ... Autoantibodies are antibodies the body makes against itself ... Both type 1 diabetes and Sjogren's syndrome are autoimmune diseases, which cause the body to attack itself" - See Jarrow green tea at iHerb.
• Coffee Drinking May Help Protect Against Type 2 Diabetes - Medscape, 10/9/08 - "Compared with participants who reported not drinking coffee daily, those who reported drinking 4 or more cups of coffee daily had a 30% reduction in the risk for diabetes ... Compared with participants who reported not drinking black tea daily, those who reported drinking 1 or more cups of black tea daily had a suggestive 14% reduction in the risk for diabetes ... There was no apparent association with green tea"
• Adiponectin May Be a Marker for Type 2 Diabetes - Medscape, 9/3/08 - "Adiponectin levels were associated with a significantly lower risk for type 2 diabetes in multivariate models that adjusted for body mass index (BMI). For the highest quintiles vs the lowest quintiles, odds ratio (OR) was 0.17 (95% confidence interval [CI], 0.12 - 0.25) for total adiponectin and 0.10 (95% CI, 0.06 - 0.15) for high-molecular-weight adiponectin. Even after adjustment for total adiponectin, a higher ratio of high-molecular-weight adiponectin to total adiponectin was associated with a statistically significantly lower risk for type 2 diabetes (OR, 0.45; 95% CI, 0.31 - 0.65) "
• Broccoli Could Reverse The Heart Damaging Effects Of Diabetes - Science Daily, 8/26/08 - "Our study suggests that compounds such as Sulforaphane from broccoli may help counter processes linked to the development of vascular disease in diabetes"
• Effect of vitamin K supplementation on insulin resistance in older men and women - Diabetes Care. 2008 Aug 12 - "The effect of 36-month vitamin K supplementation on HOMA-IR differed by sex (sex-by-treatment interaction: P = 0.02). HOMA-IR was statistically significantly lower at the 36-month visit among men in the supplement group vs. the men in the control group (P = 0.01) after adjustment for baseline HOMA-IR, BMI, and body weight change. There were no statistically significant differences in outcome measures between intervention groups in women ... Vitamin K supplementation for 36 months at doses attainable in the diet may reduce progression of insulin resistance in older men" - See vitamin K products at iHerb.
• Broccoli can reverse diabetic heart damage, say researchers - Nutra USA, 8/8/08 - "Our study suggests that compounds such as Sulforaphane from broccoli may help counter processes linked to the development of vascular disease in diabetes ... Published in the journal Diabetes Care, the epidemiological study of 71,346 female nurses found for every additional serving of green leafy vegetables, the risk of developing diabetes may be reduced by almost 10 per cent" - [Abstract]
• Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease - Diabetes. 2008 Aug 4 - "Sulforaphane (SFN) is an activator of transcription factor NF-E2-related factor-2 (nrf2) that regulates gene expression through the promoter antioxidant response element (ARE). Nrf2 regulates the transcription of a battery of protective and metabolic enzymes ... We conclude that activation of nrf2 may prevent biochemical dysfunction and related functional responses of endothelial cells induced by hyperglycemia in which increased expression of transketolase has a pivotal role" - [Nutra USA]
• Vitamin C may help lower diabetes risk - MSNBC, 8/7/08 - "the likelihood of developing diabetes was 62 percent lower in men and women with the highest circulating vitamin C levels, relative to men and women with the lowest vitamin C levels" - See vitamin C products at iHerb.
• Vitamin C-rich diet may slash diabetes risk - Nutra USA, 7/29/08 - "Increased blood levels of vitamin C may reduce the risk of developing diabetes by 62 per cent ... Correlating blood levels of vitamin C and diabetes, the researchers found that men and women with the highest blood levels (at least 1.10 and 1.29 mg/dL, respectively) had a 62 per cent reduction in their risk of developing type-2 diabetes, compared to men and women with the lowest blood levels (less than 0.56 and 0.77 mg/dL, respectively)" - See vitamin C products at iHerb.
• Green Vegetables, Fruit Intake Linked to Lower Risk for Diabetes in Women - Medscape, 7/8/09 - "Women who have a higher intake of green leafy vegetables and fruit have a lower risk for type 2 diabetes, whereas those who have a higher intake of fruit juices may have an increased risk for the disease ... An increase of 3 servings of total fruit and vegetable consumption per day was not linked to the development of diabetes (multivariate-adjusted hazard ratio [HR], 0.99; 95% confidence interval [CI], 0.94 -1.05), However, an increase in whole fruit consumption of 3 servings per day was associated with a lower risk for type 2 diabetes (HR, 0.82 ... An increase of 1 serving per day of green leafy vegetables was linked to a slightly lower hazard of diabetes (HR, 0.91; 95% CI, 0.84 - 0.98). In contrast, an increase of 1 serving per day of fruit juice consumption was associated with an increased risk for diabetes (HR, 1.18"
• Advanced glycation end products and diabetic foot disease - Diabetes Metab Res Rev. 2008 May-Jun;24 Suppl 1:S19-24 - "recent clinical studies have shown that the AGE-breakers may be able to decrease adverse vascular effects of glycation with few side effects"
• Cure Diabetes Surgically? - Dr. Weil, 6/12/08
• Common Cooking Spice Found In Curry Shows Promise In Combating Diabetes And Obesity - Science Daily, 6/20/08 - "turmeric-treated mice were less susceptible to developing Type 2 diabetes, based on their blood glucose levels, and glucose and insulin tolerance tests. They also discovered that turmeric-fed obese mice showed significantly reduced inflammation in fat tissue and liver compared to controls. They speculate that curcumin, the anti-inflammatory, anti-oxidant ingredient in turmeric, lessens insulin resistance and prevents Type 2 diabetes in these mouse models by dampening the inflammatory response provoked by obesity" - See Curcumin/turmeric products at iHerb.
• Chromium ingredient may have diabetes benefits: study - Nutra USA, 6/11/08 - "This suggests that [niacin-bound chromium] is more effective form of [chromium (III) ion] in preventing vascular inflammation in diabetic rats, and thereby, can potentially reduce risk of CVD in diabetes ... ChromeMate is also highly effective in helping maintain healthy blood sugar levels and body weight, which is important for people with diabetes. Given the close link between diabetes and cardiovascular disease, ChromeMate represents a triple benefit in promoting good health" - See ChromeMate® products at iHerb.
• Sun Exposure And Vitamin D Levels May Play Strong Role In Risk Of Type 1 Diabetes In Children - Science Daily, 6/5/08 - "This research suggests that childhood type 1 diabetes may be preventable with a modest intake of vitamin D3 (1000 IU/day) for children, ideally with 5 to 10 minutes of sunlight around noontime, when good weather allows"
• The Traditional Mediterranean Diet Protects Against Diabetes, Study Suggests - Science Daily, 5/30/08 - "A high adherence to the diet was associated with an 83% relative reduction in the risk of developing diabetes"
• Red Wine Could Benefit Patients With Diabetes - Medscape, 5/16/08 - "New research suggests that resveratrol, a chemical commonly found in red wine, has the ability to lower blood-sugar levels, but it might also produce certain unpleasant adverse effects ... The concern is that you could lower glucose in diabetics but at the same time. . . [lower] glucose levels in the brain or in other important tissues" - Does that last part make sense?  Is there anything that selectively lowers blood-sugar, i. e., lowers the blood without the brain?  And isn't it the high blood sugar in the brain that they believe is the reason the Alzheimer's rate is so high in diabetics?  And isn't it the advance glycation end products that are partly responsible for damage to important tissues?  Sounds like a biased article to me.  See Jarrow Resveratrol 100 at iHerb.
• Pine bark extract may boost diabetics' heart health - Nutra USA, 5/12/08 - "recruited diabetic subjects with an average age of 60 and randomly assigned them to receive daily supplements of Pycnogenol (125 mg) or placebo for 12 weeks ... All subjects were receiving pharmaceutical anti-hypertension treatment (angiotensin- converting enzyme [ACE] inhibitors) ... 58.3 per cent of subjects in the Pycnogenol group experienced blood pressure control, defined as attaining a stable systolic blood pressure, compared to 20.8 per cent in the placebo group ... use of ACE inhibitors was reduced by 50 per cent in the group receiving the pine bark extract ... a 23.7 mg/dL reduction in fasting blood glucose levels in the Pycnogenol group, compared to only 5.7 mg/dL in the placebo group" - See Pine Bark/Pycnogenol products at iHerb.
• Effects of niacin on glucose control in patients with dyslipidemia - Mayo Clin Proc. 2008 Apr;83(4):470-8 - "the effects of niacin (</=2.5 g/d), alone or in combination with statins, on fasting glucose (an increase of 4%-5%) and hemoglobin A1c levels (an increase of </=0.3%) are modest, transient or reversible, and typically amenable to adjustments in oral hypoglycemic regimens without discontinuing niacin. Niacin therapy was infrequently associated with incident diabetes or the need for new insulin prescriptions. Studies showed important clinical benefits of niacin or niacin-statin regimens despite modest effects on glucose control. On a population basis, significant reductions in incidences of cardiovascular events and the degree of atherosclerotic progression associated with long-term niacin (or niacin-statin) therapy in patients with diabetic dyslipidemia outweigh the typically mild effects of this therapy on glycemic regulation"
• Red Wine, Tea, May Help Regulate Blood Sugar In Type 2 Diabetics, Research Suggests - Science Daily, 4/2/08 - "Both red and white wines were tested in the laboratory using in vitro enzyme studies to determine how well they could inhibit the activity of a target enzyme called alpha-glucosidase, responsible for triggering the absorption of glucose by the small intestine. Red wine was the winner, able to inhibit the enzyme by nearly 100 percent. Values for white wine hovered around 20 percent ... red wine contains roughly ten times more polyphenolics than white wine"
• Grape Skin Compound Fights The Complications Of Diabetes - Science Daily, 3/20/08 - "resveratrol, a compound present naturally in grape skin, can protect against the cellular damage to blood vessels caused by high production of glucose in diabetes" - See Jarrow Resveratrol 100 at iHerb.
• Vitamin D May Cut Child Diabetes Risk - WebMD, 3/12/08 - "giving infants vitamin D supplements cuts their risk of type 1 diabetes by 29% ... infants in wintry Finland are 400 times more likely than a child in sunny Venezuela to have childhood diabetes" - See vitamin D products at iHerb.
• Vitamin D improves endothelial function in patients with Type 2 diabetes mellitus and low vitamin D levels - Diabet Med. 2008 Feb 13 - "Vitamin D supplementation significantly decreased systolic blood pressure by 14 mmHg compared with placebo ... Vitamin D insufficiency is common in patients with Type 2 diabetes during winter in Scotland. A single large dose of oral vitamin D2 improves endothelial function in patients with Type 2 diabetes and vitamin D insufficiency" - See vitamin D products at iHerb.
• R-alpha-Lipoic acid and acetyl-L: -carnitine complementarily promote mitochondrial biogenesis in murine 3T3-L1 adipocytes - Diabetologia. 2008 Jan;51(1):165-74 - "Treatments with the combination of LA and ALC at concentrations of 0.1, 1 and 10 mumol/l for 24 h significantly increased mitochondrial mass, expression of mitochondrial DNA, mitochondrial complexes, oxygen consumption and fatty acid oxidation in 3T3L1 adipocytes. These changes were accompanied by an increase in expression of Pparg, Ppara and Cpt1a mRNA, as well as increased expression of peroxisome proliferator-activated receptor (PPAR) gamma coactivator 1 alpha (Ppargc1a), mitochondrial transcription factor A (Tfam) and nuclear respiratory factors 1 and 2 (Nrf1 and Nrf2). However, the treatments with LA or ALC alone at the same concentrations showed little effect on mitochondrial function and biogenesis" - See Doctor's Best, Best Stabilized R-Lipoic Acid Na-RALA at iHerb and Doctor's Best acetyl-l-carnitine at iHerb.
• Lipoic acid and carnitine combo show diabetes potential - Nutra USA, 2/18/08 - [Abstract] - "the combination of LA and LCAR increased the mass, oxygen consumption, mitochondrial DNA expression, and fatty acid oxidation in the fat cells ... However, the treatments with LA or ALC alone at the same concentrations showed little effect on mitochondrial function and biogenesis ... Lipoic acid and acetyl-L-carnitine have become very hot after our reports on the complementary effects on improving memory and ambulatory activity in old rats" - See Acetyl-l-carnitine products at iHerb and Doctor's Best, Best Stabilized R-Lipoic Acid Na-RALA at iHerb.
• Caffeine Bad for Diabetes - WebMD, 1/28/08 - "On the days the patients took caffeine, their blood-sugar levels were 8% higher ... Caffeine increases blood glucose by as much as oral diabetes medications decrease it ... Lane warns against reading too much into this small, 10-patient study ... Several studies have found that coffee drinkers -- especially those who drink a lot of coffee -- have a lower risk of diabetes than do other people. So how can coffee both protect against diabetes and worsen diabetes? ... it is becoming increasingly clear it is not the caffeine that is beneficial. The picture is now evolving where we see that some other components of coffee besides caffeine may be beneficial in long-term in reduction of diabetes risk"
• How Antioxidant Therapy May Play A Role In The Treatment Of Type 2 Diabetes - Science Daily, 1/11/08 - "Mice fed a high-fat, high-sucrose diet (HFHSD) developed insulin resistance and type 2 diabetes ... mitochondrial defects were present in diabetic, but not pre-diabetic glucose intolerant, mice ... ROS production coincided with mitochondrial dysfunction, and antioxidant treatment blocked the mitochondrial alterations in muscle cells"
• The Canadian Trial of Carbohydrates in Diabetes (CCD), a 1-y controlled trial of low-glycemic-index dietary carbohydrate in type 2 diabetes: no effect on glycated hemoglobin but reduction in C-reactive protein - Am J Clin Nutr. 2008 Jan;87(1):114-25 - "In subjects with T2DM managed by diet alone with optimal glycemic control, long-term HbA(1c) was not affected by altering the GI or the amount of dietary carbohydrate. Differences in total:HDL cholesterol among diets had disappeared by 6 mo. However, because of sustained reductions in postprandial glucose and CRP, a low-GI diet may be preferred for the dietary management of T2DM"
• Legume and soy food intake and the incidence of type 2 diabetes in the Shanghai Women's Health Study - Am J Clin Nutr. 2008 Jan;87(1):162-7 - "The multivariate-adjusted relative risk of type 2 DM for the upper quintile compared with the lower quintile was 0.62 (95% CI: 0.51, 0.74) for total legumes and 0.53 (95% CI: 0.45, 0.62) for soybeans"
• Fish Oil Supplements Cut Adiposity in Type 2 Diabetics - Medscape, 1/3/08 - "Two months of daily fish oil supplements reduces adiposity and atherogenic markers in women with type 2 diabetes" - See Mega Twin EPA at iHerb.
• Omega-3 shows benefits for fat loss in diabetics - Nutra USA, 12/13/07 - "either daily supplements of fish oil (three grams, providing 1.8 grams of omega-3) or placebo (paraffin oil) for two months ... At the end of the study, Kabir and co-workers report significant reductions in total fat mass and the diameter of fat cells beneath the surface of the skin (subcutaneous adipocytes) in the omega-3, but not the placebo, group ... risk factors for plaque formation in the arteries (atherogenic markers), such as triacylglycerol levels and the ration of triacylglycerol to HDL ('good') cholesterol, were significantly lower as a result of omega-3 supplementation" - [Abstract] - See Mega Twin EPA at iHerb.
• Treatment for 2 mo with n 3 polyunsaturated fatty acids reduces adiposity and some atherogenic factors but does not improve insulin sensitivity in women with type 2 diabetes: a randomized controlled study - Am J Clin Nutr. 2007 Dec;86(6):1670-9 - "A moderate dose of n-3 PUFAs for 2 mo reduced adiposity and atherogenic markers without deterioration of insulin sensitivity in subjects with type 2 diabetes. Some adipose tissue inflammation-related genes were also reduced. These beneficial effects could be linked to morphologic and inflammatory changes in adipose tissue" - See Mega Twin EPA at iHerb.
• Vinegar at Bedtime Moderates Waking Glucose Level in Type 2 Diabetics - Medscape, 12/4/07 - "The investigators report that the vinegar treatment was especially effective for subjects with a typical fasting glucose greater than 7.2 mmol/L (n = 6). Fasting glucose in these participants was reduced 6% compared with a reduction of 0.7% in those with a typical fasting glucose less than 7.2 mmol/L" - See Source Naturals, Apple Cider Vinegar.  1 Source Natural 500 mg tablet equals 2 tsb of vinegar.  4.5 tablets equals about 3 tablespoons by my calculations.
• Glycemic Index, Glycemic Load, and Cereal Fiber Intake and Risk of Type 2 Diabetes in US Black Women - Arch Intern Med. 2007 Nov 26;167(21):2304-9 - "Increasing cereal fiber in the diet may be an effective means of reducing the risk of type 2 diabetes, a disease that has reached epidemic proportions in black women"
• Prospective Study of Dietary Carbohydrates, Glycemic Index, Glycemic Load, and Incidence of Type 2 Diabetes Mellitus in Middle-aged Chinese Women - Arch Intern Med. 2007 Nov 26;167(21):2310-6 - "High intake of foods with a high glycemic index and glycemic load, especially rice, the main carbohydrate-contributing food in this population, may increase the risk of type 2 diabetes mellitus in Chinese women"
• High-glycemic Index Carbohydrates Associated With Risk For Developing Type 2 Diabetes In Women - Science Daily, 11/26/07 - "Our results indicate that black women can reduce their risk of diabetes by eating a diet that is high in cereal fiber ... In another study ... Women who consumed more carbohydrates overall were more likely to develop diabetes--when they were split into five groups based on carbohydrate intake, those in the group consuming the most (about 337.6 grams per day) had a 28 percent higher risk than those in the group consuming the least (about 263.5 grams per day). Women who ate diets with a higher glycemic index and who ate more staples such as bread, noodles and rice specifically also had an increased risk. Women who ate 300 grams or more of rice per day were 78 percent more likely to develop diabetes than those who ate less than 200 grams per day"
• Vitamin E Could Help 40% Of Diabetics Ward Off Heart Attacks - Science Daily, 11/23/07 - "After 18 months of treatment, people with the haptoglobin (Hp) 2-2 gene who took 400 International Units (IU) of vitamin E daily had more than 50 percent fewer heart attacks, strokes, and related deaths than Hp 2-2 patients who took a placebo pill. 40% of individuals with diabetes carry the Hp 2-2 gene" - Note:  Only the alpha-tocopherol form of vitamin E is measured in IUs and I'm leery of only taking that form.  See my vitamin E page for more information.  See:
  • Effect of oral supplementation with D-alpha-tocopherol on the vitamin E content of human low density lipoproteins and resistance to oxidation - J Lipid Res. 1991 Aug;32(8):1325-32 - "gamma-Tocopherol significantly decreased in plasma and LDL during vitamin E (alpha-tocopherol) supplementation" - See See Jarrow FamilE (contains all eight members of the vitamin E family) at iHerb.
• Higher Vitamin D Levels May Lower Type 2 Diabetes Risk - Medscape, 11/19/07 - "During a 17-year follow-up of a Finnish cohort of approximately 4,000 men and women, researchers demonstrated that individuals with a higher serum vitamin D level had a 40% lower risk of developing type 2 diabetes than those with lower values" - See vitamin D products at iHerb.
• Can Calcium & Vitamin D Reduce Diabetes Risk? - Physician's Weekly, 11/19/07 - "found a relatively consistent association between low vitamin D status, calcium or dairy intake, and prevalent type 2 diabetes based on the utilization of vitamin D and/or calcium supplementation ... a combination of vitamin D and calcium supplements may play a role in type 2 diabetes prevention particularly in high-risk populations"
• Phenotype of subjects with type 2 diabetes mellitus may determine clinical response to chromium supplementation - Metabolism. 2007 Dec;56(12):1652-5 - "Sixty-three percent of the subjects with type 2 diabetes mellitus responded to the Cr treatment as compared with 30% with placebo ... Subject phenotype appears to be very important when assessing the clinical response to Cr because baseline insulin sensitivity was found to account for nearly 40% of the variance in the clinical response to Cr"
• Genistein and daidzein prevent diabetes onset by elevating insulin level and altering hepatic gluconeogenic and lipogenic enzyme activities in non-obese diabetic (NOD) mice - Diabetes Metab Res Rev. 2007 Oct 11 - "Blood glucose levels of genistein and daidzein groups were 40 and 36% of control value at the end of study (9th week). The genistein and daidzein supplements increased insulin/glucagon ratio and C-peptide level with preservation of insulin staining beta-cell of pancreas in the NOD mice ... The supplementation of genistein and daidzein are seemingly helpful for preventing IDDM onset"
• Red Wine Compound May Curb Diabetes - WebMD, 10/2/07 - "Resveratrol curbs insulin resistance in mice ... According to our findings, people might need to drink about three liters of red wine each day to get sufficient resveratrol -- about 15 milligrams -- for its biological effects" - See resveratrol products at iHerb.
• Omega-3 May Lower Type 1 Diabetes Risk - WebMD, 9/25/07 - "Eating a diet rich in omega-3 fats may help keep high-risk children from developing type 1 diabetes" - See Mega Twin EPA at iHerb.
• Glucose Benefits of Wine in Diabetics - Medscape, 9/21/07 - "At the end of three months, 91 subjects remained in the study; those in the alcohol-intervention group experienced a statistically significant drop in fasting plasma glucose, from a mean of 139.6 mg/dL to 118 mg/dL"
• Study: The Best Exercise for Diabetes - Time, 9/18/07 - "Compared with controls, patients in the aerobic group had a reduction of .51% in their hemoglobin A1C values — a test that measures blood-sugar control over the previous two to three months (lower is better). The weight-training group had a .38% reduction compared with controls. But the combined exercise group showed further improvements: in those patients, the A1C values went down an additional .46% over the aerobic group, and .59% over the weight-training group. Compared to controls, the combo exercisers had a nearly 1% lower A1C reading"
• Vitamin B1 Deficiency Key To Vascular Problems For Diabetic Patients, Study Suggests - Science Daily, 8/7/07 - "thiamine concentration in blood plasma was decreased 76% in type 1 diabetic patients and 75% in type 2 diabetic patients ... the decreased availability of thiamine in vascular cells in diabetes was linked to a marker of microvascular and macrovascular complications"
• Magnesium intake and risk of type 2 diabetes: a meta-analysis - J Intern Med. 2007 Aug;262(2):208-14 - "The overall relative risk for a 100 mg day(-1) increase in magnesium intake was 0.85"
• Flavonoids in Orange Juice Make It a Healthy Drink, Despite the Sugar - Doctor's Guide, 7/17/07 - "the two types of flavonoids in orange juice -- hesperetin and naringenin -- inhibited ROS generation by 52% and 77%, respectively ... Our data are relevant to patients with diabetes ... because stress from ROS and inflammation are increased significantly in this population and may contribute to development of atherosclerosis"
• Vitamin C 'benefits diabetics' - BBC News, 6/28/07 - "Vitamin C neutralises free radicals, while Telmisarten stimulates the natural removal of the molecules by cells"
• Can Blindness Be Prevented Through Diet? - Science Daily, 6/24/07 - "Increasing intake of the omega-3 fatty acids DHA and EPA, found in popular fish-oil supplements, may protect against blindness resulting from abnormal blood vessel growth in the eye ... Mice on the omega-3 diet, rich in DHA (docosahexaenoic acid) and its precursor EPA (eicosapentaenoic acid), had less initial vessel loss in the retina than the omega-6-fed mice: the area with vessel loss was 40 to 50 percent smaller" - See Mega Twin EPA at iHerb or Jarrow Max DHA at iHerb.
• Effect of Chromium Supplementation on Glucose Metabolism and Lipids: A Systematic Review of Randomized Controlled Trials - Diabetes Care. 2007 May 22 - "There was no benefit in individuals without diabetes ... Chromium supplementation significantly improved glycemia among patients with diabetes" - See chromium products at iHerb.
• Fiber May Fight Diabetes - WebMD, 5/15/07
• Grain Fiber And Magnesium Intake Associated With Lower Risk For Diabetes - Science Daily, 5/14/07 - "those who consumed the most cereal fiber had a 33 percent lower risk of developing diabetes than those who took in the least, while those who consumed the most magnesium had a 23 percent lower risk than those who consumed the least. There was no association between fruit or vegetable fiber and diabetes risk"
• Muesli with 4 g oat beta-glucans lowers glucose and insulin responses after a bread meal in healthy subjects - Eur J Clin Nutr. 2007 Apr 4 - "Muesli enriched with 4 g of beta-glucans reduces postprandial glucose and insulin levels to a breakfast based on high glycaemic index products. A total of 4 g of beta-glucans from oats seems to be a critical level for a significant decrease in glucose and insulin responses in healthy people"
• Exercise Pivotal In Preventing And Fighting Type II Diabetes - Science Daily, 2/9/07 - "A new study at the University of Missouri-Columbia says that acute exercise - as little as 15 minutes a day - can have a profound influence on preventing and fighting the disease"
• The Effects of Calcium and Vitamin D Supplementation on Blood Glucose and Markers of Inflammation in Non-diabetic Adults - Diabetes Care. 2007 Feb 2 - "Among participants with IFG at baseline those who took combined calcium-vitamin D supplements had a lower rise in FPG at 3 years compared to those on placebo"
• More support for beta-glucan’s anti-diabetes benefits - Nutra USA, 1/3/07
• Research Affirms the Benefits of Combination of Chromium Picolinate and Biotin for Improving Blood Sugar in People with Type 2 Diabetes - Doctor's Guide, 12/20/06 - "The 30-day study examined 36 overweight or obese poorly controlled patients with type 2 diabetes taking Diachrome who were already receiving oral anti-diabetic drug(s). The results also showed a significantly greater reduction in the total area under the curve for glucose (AUCg) during the oral glucose tolerance test (OGTT) for the treatment group (mean change -9.7%) compared with the placebo group (mean change +5.1%)"
• The Effect of Chromium Picolinate and Biotin Supplementation on Glycemic Control in Poorly Controlled Patients with Type 2 Diabetes Mellitus: A Placebo-Controlled, Double-Blinded, Randomized Trial - Diabetes Technol Ther. 2006 Dec;8(6):636-643 - "randomized to receive 600 microg of chromium as chromium picolinate and biotin (2 mg/day) ... supplementation with a combination of chromium picolinate and biotin in poorly controlled patients with diabetes receiving antidiabetic therapy improved glucose management and several lipid measurements. Chromium picolinate/ biotin supplementation may represent an effective adjunctive nutritional therapy to people with poorly controlled diabetes with the potential for improving lipid metabolism" - See iHerb or Vitacost chromium products and iHerb or Vitacost biotin products.
• Chromium Picolinate Supplements Improve Glycemic Control - Physician's Weekly, 11/13/06 - "Patients who received 1,000 µg CrPic demonstrated significant improvements in insulin sensitivity and glucose control when compared with placebo. Patients in the CrPic arm also gained less weight (0.9 kg vs 2.2 kg) than those in the placebo arm and had a smaller increase in body fat (0.12% vs 1.17%)" - See iHerb or Vitacost chromium products.
• Milk Thistle May Help Treat Diabetes - WebMD, 10/31/06 - "At the study's start, the patients had similar blood sugar levels and blood sugar control ... But after taking the tablets for four months, the milk thistle group showed better blood sugar control and cholesterol and triglyceride levels" - See iHerb or Vitacost silymarin products.
• Milk thistle extract could help diabetes control - Nutra USA, 10/30/06 - "fasting glucose levels of the supplementation group decreased from 156 milligrams per decilitre (mg/dL) of blood to 133 mg/dL, while the placebo group's fasting glucose levels increased from 167 to 188 mg/dL" - See iHerb or Vitacost silymarin products.
• Serum 25-hydroxyvitamin D3 concentrations and carotid artery intima-media thickness among type 2 diabetic patients - Clin Endocrinol (Oxf). 2006 Nov;65(5):593-597 - "The prevalence of hypovitaminosis D (i.e. 25(OH)D </= 37.5 nmol/l) was higher in diabetic patients (34.0 vs 16.4%, P < 0.001) than in controls. Among diabetic patients, those with hypovitaminosis D (n = 130) had a marked increase in common carotid IMT (1.10 +/- 0.15 vs 0.87 +/- 0.14 mm, P < 0.001) when compared with their vitamin d-sufficient counterparts (n = 260). These patients also had significantly higher haemoglobin A1c, fibrinogen and C-reactive protein (hs-CRP) concentrations. In multivariate regression analysis, low 25(OH)D concentrations independently predicted carotid IMT (P < 0.001) in people with type 2 diabetes after adjustment for classical risk factors, diabetes duration, HbA1c, calcium, renal function tests, inflammatory markers, use of medications, and presence of the metabolic syndrome" - See iHerb or Vitacost vitamin D products.
• Coffee May Protect Against Diabetes - WebMD, 10/25/06 - "After adjusting for other known diabetes risk factors, the researchers concluded that both past and current drinkers of caffeinated coffee had about a 60% reduction in diabetes risk, compared with study participants who never drank coffee ... A similar reduction in risk was seen among the roughly one-third of study participants with impaired glucose tolerance"
• Chromium for Diabetes: Evidence of Benefits Grows - New Hope Natural Media Online, 10/23/06 - "Compared with those who took glipizide and placebo, people taking glipizide plus chromium (500 mcg twice a day as chromium picolinate) experienced multiple benefits, including significantly improved insulin sensitivity, less weight gain, less abdominal fat, lower percent body fat, and lower glycohemoglobin (an indicator of sugar-induced damage to tissues caused by diabetes)"
• Silymarin, Might Help in Insulin Resistance, Cancer - thenutritionreporter.com
• Dietary Magnesium May Reduce Risk for Diabetes in Black Women - Medscape, 10/9/06 - "41,186 women enrolled in the Black Women's Health Study ... Higher magnesium intakes in the highest vs the lowest quintile were associated with lower incidence of diabetes mellitus with an adjusted HR of 0.69" - See iHerb or Vitacost magnesium products.
• Pine bark extract could improve diabetic microangiopathy - Nutra USA, 10/6/06
• Folic acid improves endothelial dysfunction in type 2 diabetes--an effect independent of homocysteine-lowering - Vasc Med. 2006 May;11(2):101-9 - "2 weeks of folic acid supplementation can improve endothelial dysfunction in type 2 diabetics independent of homocysteine-lowering" - See iHerb or Vitacost folic acid products.
• Compound In Dairy Products Targets Diabetes - Science Daily, 8/4/06 - "Researchers first became interested in CLA when it was shown to inhibit a variety of cancers such as breast, skin and colon in mice, and further research showed effects on circulating cholesterol and inflammation ... he used CLA on mice prone to adult onset (Type-2) diabetes. Results indicated that the mice had an improvement in insulin action, and a decrease in circulating glucose" - See iHerb or Vitacost CLA products.
• Chromium Improves Glycemic Control When Sulfonylurea Is Insufficient - Medscape, 8/3/06 - "By the end of the randomized treatment period, mean fasting glucose had decreased by 31.0 mg/dL in the CrPic group, which was significantly superior to the mean 11.3 mg/dL decrease in the placebo group ... Participants receiving placebo gained weight and percent body fat during the randomized treatment period, whereas subjects receiving CrPic experienced an increase in fat-free mass vs baseline. Only subjects receiving placebo had increases in total abdominal, visceral, and abdominal subcutaneous fat" - See iHerbor Vitacost chromium products.
• Chromium picolinate supplementation attenuates body weight gain and increases insulin sensitivity in subjects with type 2 diabetes - Diabetes Care. 2006 Aug;29(8):1826-32 - "1,000 mug Cr as CrPic ... CrPic supplementation in subjects with type 2 diabetes who are taking sulfonylurea agents significantly improves insulin sensitivity and glucose control. Further, CrPic supplementation significantly attenuated body weight gain and visceral fat accumulation compared with the placebo group" - See iHerbor Vitacost chromium products.
• Low-Fat Vegan Diet May Treat Diabetes - WebMD, 7/26/06 - "43% of people with type 2 diabetes who followed a low-fat vegan diet for 22 weeks reduced their need to take medications to manage their disease compared with 26% of those who followed the diet recommended by the American Diabetes Association"
• Exercise in Itself Improves Blood Glucose Control in Type 2 Diabetes - Doctor's Guide, 7/24/06 - "exercise helps regulate blood glucose (sugar) levels, increases the body's sensitivity to insulin, and decreases blood lipids (fats) while also helping to burn body fat ... Participants who exercised had an overall decrease of 0.6% of A1c levels. While that may not sound like much, it represents a 30% improvement towards the goal of attaining an A1c of 7%, and a 20% improvement towards a normal A1c of 6%"
• Effects of weight loss on insulin sensitivity and arterial stiffness in overweight adults - Metabolism. 2006 Jul;55(7):907-11 - "In overweight adults, 6 months of weight loss resulted in improvements in body composition, insulin sensitivity, lipid profile, and brachial artery compliance and distensibility"
• The influence of chromium chloride-containing milk to glycemic control of patients with type 2 diabetes mellitus: a randomized, double-blind, placebo-controlled trial - Metabolism. 2006 Jul;55(7):923-7 - "one group to receive chromium-containing milk powder (chromium 200 mug/20 g milk powder) and the other to receive placebo twice a day for 16 weeks ... The chromium group demonstrated a lower FPG and fasting insulin (-38.1 +/- 9.2 vs 63 +/- 8. 5 mg/dL and -1.7 +/- 0.2 vs 1.9 +/- 0.3 muU/mL, respectively"
• Vitamin D and calcium intake in relation to type 2 diabetes in women - Diabetes Care. 2006 Mar;29(3):650-6 - "A combined daily intake of >1,200 mg calcium and >800 IU vitamin D was associated with a 33% lower risk of type 2 diabetes with RR of 0.67 (0.49-0.90) compared with an intake of <600 mg and 400 IU calcium and vitamin D, respectively"
• Effect of chromium on the insulin resistance in patients with type II diabetes mellitus - Folia Med (Plovdiv). 2005;47(3-4):59-62 - "We found a significant decrease of the immune-reactive insulin and the insulin resistance index after a two-month application of chromium 30 microg daily (1 tablet of chrome picolinate) ... Chromium included early in the complex therapy of diabetes is beneficial in the reduction of the degree of insulin resistance"
• Effect of nicotinamide on newly diagnosed type 1 diabetic children - Acta Pharmacol Sin. 2006 Jun;27(6):724-7 - "even low doses of oral NA given to children with newly diagnosed type 1 diabetes may reduce insulin requirements and prolong the honeymoon period"
• Dairy Products May Lower Risk of Type 2 Diabetes in Men - Medscape, 5/10/06 - "An increase of 1 serving of dairy product per day was associated with a 9% reduced risk of developing DM"
• Fiber Good, and Not Just for Your Gut - WebMD, 4/13/06 - "the women who ate the oat fiber over the short three-day time period became significantly more sensitive to insulin"
• Insoluble fibre could protect against diabetes, more evidence - Nutra USA, 4/12/06 - "eating a fibre-enriched bread for only three days improved insulin sensitivity in overweight and obese women by eight per cent"
• Calcium, vitamin D may lower diabetes risk - Nutra USA, 4/3/06 - "A combined daily intake of more than 1,200 milligrams of calcium and more than 800 international units (IU) of vitamin D was associated with a 33 per cent lower risk of type-2 diabetes"
• Cereal fiber improves whole-body insulin sensitivity in overweight and obese women - Diabetes Care. 2006 Apr;29(4):775-80 - "Increased insoluble dietary fiber intake for 3 days significantly improved whole-body insulin sensitivity"
• Magnesium Lowers Heart, Diabetes Risks - WebMD, 3/27/06 - "people in the study who consumed the most magnesium had a 31% lower risk of developing metabolic syndrome, compared with people who ate the least"
• Chromium supplement offers diabetes hope – animal study - Nutra USA, 2/7/06 - "Obese rats treated with chromium picolinate had significantly improved glucose disposal rates" - See iHerbor Vitacost chromium products.
• Coffee May Decrease Risk of Developing Type 2 Diabetes in Women - Medscape, 2/6/06 - "The RR of type 2 diabetes was 0.87 for 1 cup per day, 0.58 for 2 to 3 cups per day, and 0.53 for 4 or more cups per day vs no coffee consumption"
• Catalytic amounts of fructose may improve glucose tolerance in subjects with uncontrolled non-insulin-dependent diabetes - Clin Nutr. 2006 Jan 3 - "were assigned to either fructose or maltodextrin supplementation (7.5g) tri-daily after each main meal ... After 1 month fructosamin levels decreased in the fructose-supplemented group but not in the maltodextrin-supplemented group (P<0.052). Hgb(A1C) levels decreased with time in both groups but were significantly lower at 2 months in the fructose group as compared to the maltodextrin group" - See fructose products at iHerb.
• Three-week Diet-Exercise Study Shows 50 Percent Reversal In Metabolic Syndrome, Type 2 Diabetes - Science Daily, 1/16/06 - "The study shows, contrary to common belief, that Type 2 diabetes and metabolic syndrome can be reversed solely through lifestyle changes ... Participants did lose two to three pounds per week, but they were still obese after the 3-week study ... The daily diet was low fat (12-15% of calories), moderate protein (15-20% of calories), and high in unrefined carbohydrates (65-70% of calories) and fiber (more than 40 grams) ... Natural foods -- whole grains (five or more servings daily), vegetables (four or more servings), and fruits (three or more servings) -- were the main source of daily carbohydrates ... Aside from meat and dairy, the study participants could eat as much as they wanted"
• Controlling Blood Sugar with Cinnamon and Coffee Berry - Life Extension Magazine, 12/05
• Low Levels of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 in Patients with Newly Diagnosed Type 1 Diabetes - Horm Metab Res. 2005 Nov;37(11):680-683 - "Mean levels of both 25OHD (3) and 1,25-(OH) (2)D (3) were significantly lower in patients compared to controls ... These findings suggest that vitamin D (3) may be an important pathogenic factor in type 1 diabetes"
• High-carb diet may raise diabetics’ blood pressure - Nutra USA, 11/28/05
• A New Way to Treat Diabetes? - Dr. Weil, 11/18/05
• Vitamins C and E, Magnesium and Zinc May Reduce Microalbuminuria in Type 2 Diabetes - Medscape, 9/29/05
• Study Results Show Diachrome(R) Improves Poorly-Controlled Blood Sugar Levels for People on Antidiabetic Prescription Medications - Doctor's Guide, 9/13/05 - "Study participants taking Diachrome with one or more antidiabetic medications saw an average range of 0.7 - 1.9% point reduction in HbA1c levels. The study also showed that insulin resistance was significantly reduced (P<0.05) in those taking thiazolidinediones and Diachrome ... Diachrome is a nutritional supplement specifically formulated for people with diabetes. It contains 600 mcg of chromium as Chromax(R) chromium picolinate and 2 mg of biotin" - See chromium and biotin at iHerb.
• Vinegar may help dieters eat less - Nutra USA, 9/7/05 - "Both glucose and insulin responses were about 25 per cent lower at 90 minutes when the volunteers had consumed the highest level of vinegar compared to the reference meal ... This level of vinegar is equivalent to about two to three tablespoons"
• Adult Lifestyle Biggest Risk Factor For Diabetes, Study Finds - Science Daily, 7/5/05 - "Type 2 diabetes is strongly related to overweight and lack of physical activity, and accounts for 90% of all diabetes"
• High Blood Sugar - Life Extension Magazine, 7/05 - "Long-term consumption of foods with high glycemic loads is associated with an increased risk of type II diabetes and coronary heart disease.34  ... Why trade one insulin-raising nutrient for another? It is far safer, and just as nutritious, to decrease carbohydrates and maintain protein at a reasonable level, while increasing your intake of ‘good’ unsaturated fats.”35 If fewer carbohydrates are available, the body will convert protein to glucose. This is a much slower process, so shifting the balance between carbohydrates and proteins will reduce the risk of hyperglycemia"
• Coffee May Cut Type 2 Diabetes Risk - WebMD, 7/5/05 - "Those who drank four to six cups per day had a 28% lower risk of type 2 diabetes, compared with people who drank the least coffee"
• Aerobic Exercise Helps Find Genetic Regions Linked To Prediabetes - Science Daily, 7/5/05 - "At the end of the exercise program, the insulin sensitivity of the participants had improved overall--they needed to produce less insulin to handle the same amount of glucose intake"
• Supplemental Chromium Picolinate and Biotin Appear to Decrease Blood Glucose and Lipid Levels in Type 2 Diabetics: Presented at ADA - Doctor's Guide, 6/17/05 - "Our most important finding is that chromium picolinate and biotin help to decrease hemoglobin A1c [HbA1c] values in poorly controlled diabetics ... 600 mcg chromium picolinate and biotin 2 mg/per day" - See iHerb or Vitacost biotin products.
• New Trial Shows Chromium Picolinate Reduces Weight Gain Associated with Diabetes Medication - Doctor's Guide, 6/16/05 - "The study participants who took 1,000 mcg of Chromax(R) chromium picolinate in combination with the antidiabetic medication experienced significantly lower body fat accumulation (0.12%) than the group taking medication and placebo (1.1%), particularly in the abdomen area. The study also found those taking chromium gained less weight" - See iHerb or Vitacost chromium products.
• Vitamin D Supplementation Appears to Lower Risk of Type 2 Diabetes Development in Women: Presented at ADA - Doctor's Guide, 6/13/05 - "When they compared the highest and lowest quintile cohorts of vitamin D intake from all sources, the researchers found the relative risk (RR) of type 2 diabetes was 0.72" - I read that as a 28% reduced risk.  See iHerb or Vitacost vitamin D products.
• 38 Minutes to Better Health With Diabetes - WebMD, 5/25/05
• Does Replacing DHEA Improve Insulin Sensitivity? - Physician's Weekly, 5/16/05 - "DHEA replacement “significantly increased [sulfated ester of DHEA], bioavailable testosterone, and androstenedione and reduced sex hormone–binding globulin levels.” The DHEA group also had lower fasting plasma insulin and glucagon levels. “DHEA also [significantly] reduced total cholesterol, triglycerides, LDL cholesterol, and HDL cholesterol,”" - See iHerb or Vitacost DHEA products.
• Black Tea, Green Tea Good for Diabetes - WebMD, 4/20/05 - "Black and green tea represent a potentially inexpensive, nontoxic, and, in fact, pleasurable [blood-sugar-lowering] agent"
• Tea May Help Prevent Diabetes And Cataracts - Science Daily, 4/19/05 - "At levels that would be equivalent to less than five cups of tea per day for a human, both teas significantly inhibited cataract formation relative to a control group which did not get tea, they say. The researchers found that both teas decreased glucose levels, which in turn affects other biochemical pathways that accelerate diabetic complications such as cataracts" - See iHerb or Vitacost green tea products.
• Wheat Albumin May Help Improve Glycemic Control for Type 2 Diabetics - Medscape, 3/25/05
• Type 2 Diabetes: The More Exercise, the Better - WebMD, 3/25/05
• Caffeine Tied to Blood Sugar Problems - WebMD, 3/9/05 - "caffeine reduced the men's ability to process blood sugar. It also interfered with insulin, the body's hormone that handles blood sugar ... But what about the studies that show that coffee may protect against type 2 diabetes ... Here's the catch. In the new study, caffeine came from a pill ... Coffee contains many other substances besides caffeine, such as potassium, antioxidants, and magnesium"
• Effect of L-carnitine on plasma glycemic and lipidemic profile in patients with type II diabetes mellitus - Eur J Clin Nutr. 2005 Mar 02 - "fasting plasma glucose (FPG) ... FPG in the L-carnitine group decreased significantly from 143+/-35 to 130+/-33 mg/dl (P=0.03) ... after 12 weeks of treatment" - See iHerb or Vitacost l-carnitine products.
• Vinegar as a Sweet Solution? - Science News, 12/18/04 - "2 tablespoons of vinegar before a meal—perhaps, as part of a vinaigrette salad dressing—will dramatically reduce the spike in blood concentrations of insulin and glucose that come after a meal ... vinegar cut their blood-glucose rise in the first hour after a meal by about half ... a 2-pound weight loss, on average, over the 4 weeks in the vinegar group"
• Avoid Fruit with Diabetes? - Dr. Weil, 12/28/04
• Cherries May Help Fight Diabetes - WebMD, 12/23/04
• Chemicals Found In Cherries May Help Fight Diabetes - Science Daily, 12/21/04
• What to take to keep diabetes at bay - Delicious Living, 12/04 - "Recent research suggests that magnesium keeps blood sugars from rising too high, thus staving off diabetes"
• Regular or Decaf, Coffee May Ward Off Diabetes - WebMD, 11/9/04 - "women who drank more than four cups of regular or decaffeinated coffee per day have significantly lower levels of a component of insulin than non-coffee drinkers ... This insulin component is called C-peptide"
• White Bread, Starchy Foods Linked to Diabetes - WebMD, 11/5/04 - "Participants who ate the most white bread -- more than 17 slices per week -- had the highest risk of diabetes ... A high-GI diet could also lead to insulin resistance (decreased ability for the body to respond to the hormone insulin), which can lead to diabetes ... participants who ate a lot of sugar, magnesium, and total carbohydrates had a lower risk of diabetes"
• Do Sweetened Sodas Lead to Diabetes? - Dr. Weil, 11/2/04
• Control Blood Sugar with Herbal Supplement - Healthwell, 9/30/04
• Novel Fiber Limits Sugar Absorption - Life Extension Magazine, 9/04 - "With the introduction of a new highly viscous fiber blend trademarked under the name PGX™, it may now be possible to achieve the multiple documented benefits of fiber by swallowing only a few capsules before each meal. The longevity potential associated with reducing after-meal glucose and insulin blood levels, lowering total cholesterol and LDL, and losing some weight is enormous" - See iHerb or Vitacost PGX products.
• Effect of chromium supplementation on blood glucose and lipid levels in type 2 diabetes mellitus elderly patients - Int J Vitam Nutr Res. 2004 May;74(3):178-82 - "study group received 200 microg of chromium twice a day for a three-week period ... Significant differences in the fasting blood level of glucose compared to the baseline (190 mg/dL vs 150 mg/dL, p < 0.001) were found at the end of the study. HbA1c also improved from 8.2% to 7.6% (p < 0.01). Total cholesterol was also reduced from 235 mg/dL to 213 mg/dL (p < 0.02). A trend towards lowered triglyceride levels was also observed (152 mg/dL vs 136 mg/dL)" - See iHerb or Vitacost chromium products.
• Soy Benefits Type 2 Diabetes - WebMD, 8/3/04 - "Diabetes is the leading cause of kidney failure.  The earliest sign of this complication is small amounts of protein in urine ... Those who added the soy protein powder to their diets had a 10% reduction in protein found in urine ... the soy protein supplement boosted "good" HDL cholesterol by 4%" - [Abstract]
• Antioxidant Enzyme Containing Selenium, A Major Dietary Supplement, Could Promote Type 2 Diabetes - Science Daily, 6/11/04
• Moderate Alcohol May Improve Diabetes - WebMD, 6/1/04 - "alcohol improves the body's resistance to insulin -- the hallmark of type 2 diabetes ... the evidence from large-population studies is fairly consistent and shows a reduction in risk of 30% to 40% associated with moderate drinking"
• Diabetes - Understanding And Preventing The Next Health Care Epidemic - Life Extension Magazine, 6/04
• Supplement May Lower Diabetes Heart Risks - WebMD, 5/10/04 - "Diachrome contains chromium, in the form of chromium picolinate, and biotin, which is thought to improve insulin's action to improve blood sugars ... After 30 days ... Average fasting blood glucose dropped by 26.2 mg/dL"
• Magnesium may reduce risk of diabetes - MSNBC, 5/7/04 - "The conclusions of these three studies are generally supported by earlier large population studies. Laboratory studies suggest that magnesium influences the action of insulin in the body. A lack of magnesium may worsen insulin resistance, triggering the onset of diabetes" - See iHerb or Vitacost magnesium products.
• What makes people fat, why diets don't work, and what triggers appetite? - Dr. Murray's Natural Facts, 3/17/04 - "PGX™ lowers after meal blood sugar levels by approximately 20 to 40% and also lowers insulin secretion by approximately 40% producing a whole body insulin sensitivity index improvement of nearly 50% - a phenomenal accomplishment that is unequalled by any drug or natural health product.10 PGX™ is particularly well-suited for syndrome X" - See iHerb or Vitacost PGX products.
• Drinking Lots of Coffee May Prevent Diabetes - WebMD, 3/9/04
• Natural Support for Diabetes - Dr. Murray's Natural Facts, 2/26/04
• Antioxidant-Rich Diet May Prevent Diabetes - WebMD, 2/20/04 - "people whose diets had the highest levels vitamin E were 30% less likely to develop type 2 diabetes than those who ate the least amounts of the antioxidant ... people who ate a lot of carotenoids, a type of antioxidant found in colorful fruits and vegetables, also had a lower risk of developing type 2 diabetes"
• OTC Cream Improves Blood Flow in Feet - WebMD, 1/8/04 - "arginine does increase blood flow, but it is not yet clear if this translates into fewer foot ulcers or better healing of ulcers" - See iHerb or Vitacost arginine products.
• Low Magnesium Intake May be Associated with Increased Risk for Type 2 Diabetes - Doctor's Guide, 1/6/04 - "Statistical analyses revealed a significant inverse association between magnesium intake and risk of type 2 diabetes" - See iHerb or Vitacost magnesium products.
• Coffee May Cut Type 2 Diabetes Risk - WebMD, 1/5/04 - "Those who drank six or more cups per day had the lowest risk of having type 2 diabetes compared with those who drank less coffee ... Caffeine may stimulate muscles to burn fat and sugar more efficiently and could trigger the breakdown of fat in other tissue as well"
• What You Don’t Know About Blood Sugar - Life Extension Magazine, 1/04 - "it now appears that optimal fasting blood glucose levels should probably be under 86 mg/dL ... Chromium supplements have been shown to reduce blood glucose significantly.70-74 The dose used in human studies ranges from 200 to 1000 mcg of elemental chromium a day, with best results occurring when 400 mcg or more of chromium is taken daily ... Nondiabetics using metformin may start off at 500 mg a day and gradually build up to 1000-1500 mg a day. The objective is not to take so much metformin as to induce a hypoglycemic state" - See iHerb or Vitacost chromium products.
• Magnesium Lowers Type 2 Diabetes Risk - WebMD, 12/23/03
• Magnesium Intake and Risk of Type 2 Diabetes in Men and Women - Diabetes Care. 2004 Jan;27(1):134-140 - "Our findings suggest a significant inverse association between magnesium intake and diabetes risk. This study supports the dietary recommendation to increase consumption of major food sources of magnesium, such as whole grains, nuts, and green leafy vegetables" - See iHerb or Vitacost magnesium products.
• Dietary Magnesium May Help Prevent Development of Type 2 Diabetes - Medscape, 12/23/03 - "Magnesium-containing foods can prevent development of type 2 diabetes in both men and women ... Comparing the highest with the lowest quintile of total magnesium intake ... was 0.66 ... in women and 0.67 in men" - See iHerb or Vitacost magnesium products.
• Cinnamon Helps Type 2 Diabetes - WebMD, 12/5/03
• Buckwheat May Be Beneficial For Managing Diabetes - Intelihealth, 11/18/03 - "extracts of the seed lowered blood glucose levels by 12 percent to 19 percent when fed to diabetic rats ... incorporation of buckwheat into the diet could help provide a safe, easy and inexpensive way to lower glucose levels and reduce the risk of complications associated with the disease, including heart, nerve and kidney problems"
• Managing Diabetes with Supplements? - Dr. Weil, 10/10/03
• Moderate Drinking May Curb Diabetes Risk - WebMD, 10/8/03
• Supplements for Diabetes? - Dr. Weil, 10/7/03 - "... In addition, I recommend supplementing with 1,000 mcg a day of GTF (glucose tolerance factor) chromium ..."
• High-Protein Diet Helpful in Type 2 Diabetes - Medscape, 10/6/03 - "The ratio of protein to carbohydrate to fat was 30:40:30 in the high-protein diet and 15:55:30 in the control diet ... there was a 40% decrease in the mean 24-hour integrated glucose area response after the high-protein diet. Patients on the high-protein diet also fared better in terms of decrease in glycated hemoglobin ... longer-term studies are necessary to determine the total magnitude of response, possible adverse effects, and the long-term acceptability of the diet"
• Regardless of Weight, Physical Activity Lowers Diabetes Risk - WebMD, 9/25/03 - "A new study shows a brisk 30-minute walk every day can substantially lower a person's risk of diabetes, no matter how much they weigh"
• Metformin: drug of choice for the prevention of type 2 diabetes and cardiovascular complications in high-risk subjects - Diabetes Metab. 2003 Sep;29(4):121-2 - "Metformin is unique in being not only as effective as any other oral antidiabetic therapy in controlling blood glucose, but also having an unparalleled clinical database relating to improved clinical outcomes in pre-diabetic subjects, and patients with established type 2 diabetes"
• The Chromium Connection - Natural Foods Merchandiser, 9/03 - "The body requires certain nutrients to control glucose metabolism, especially chromium, zinc and vitamins B and C ... Diabetes is devastating because of its consequences. The condition often leads to hypertension, lipid disorders, cardiovascular disease, blindness, skin problems, nerve damage, kidney disorders and loss of limbs. Although it appears chromium picolinate may benefit your customers with type 2 diabetes, supplementation represents just one facet of treatment" - See iHerb or Vitacost chromium products.
• Uses of Metformin May Extend Beyond Patients with Type 2 Diabetes - Doctor's Guide, 9/4/03 - "In type 2 diabetics, metformin appears to decrease plasma fasting glucose and HbA1c levels without causing weight gain. Metformin may also have a positive influence on a variety of cardiovascular risk factors and may be useful in preventing diabetes in overweight individuals with mild hyperglycaemia ... while further study is necessary before more widespread use is encouraged, the role of metformin may be expanded for glucose control in children and teenagers with type 2 diabetes, in non-diabetic women with PCOS, and to prevent progression to diabetes"
• Chromium Supplements Appear to Improve Glucose Sensitivity in Diabetics - Medscape, 8/29/03 - "We think that chromium picolinate can influence a person's diabetic treatment so that levels of insulin required may be reduced ... HbA1c levels decreased from 9.5% to 9% during a six-month period in patients receiving a higher dose of the supplement, a difference that was statistically significant ... The study also showed a significant reduction in cholesterol levels and trends for improvement in triglycerides in both chromium picolinate groups as well as a reduction in blood pressure in all groups" - See iHerb or Vitacost chromium products.
• Minor Weight Loss Through Exercise Provides Control Over Type 2 Diabetes - Doctor's Guide, 8/26/03 - "A relatively small decrease in body mass can have major effects in controlling type 2 diabetes"
• People Over 40 Need Frequent Exercise To Prevent Or Treat Type 2 Diabetes - Doctor's Guide, 8/18/03 - "middle-aged and older people don't sustain the increased insulin sensitivity that aerobic exercise produces ... Younger people, on the other hand, were found to maintain higher insulin sensitivity even four days after their last workout ... With a decrease in insulin sensitivity, blood glucose levels increase. High blood glucose levels, typical in diabetes, can damage virtually every organ in the body"
• Lifestyle Modification, Metformin Effective Prevention for Type 2 Diabetes - Doctor's Guide, 7/31/03 - "1,073 patients were prescribed 850 mg metformin twice daily, 1,082 had placebo twice daily, and 1,079 were prescribed an intensive program of lifestyle modification ... Incidence of diabetes was 58% lower ... in the lifestyle intervention group and 31% lower ... in the metformin group than in the placebo group"
• DHEA May Fight Heart Disease, But How? - WebMD, 7/23/03 - "taking small doses of DHEA improved insulin sensitivity and endothelial function -- two factors that contribute to the development of heart disease -- in 24 middle-aged men with high cholesterol" - See iHerb or Vitacost DHEA products.
• Randomised Trial Demonstrates Benefits of Lifestyle Modification in Type 2 Diabetes - Doctor's Guide, 7/21/03
• The Effect of Glucosamine-Chondroitin Supplementation on Glycosylated Hemoglobin Levels in Patients With Type 2 Diabetes Mellitus - Arch Intern Med. 2003;163:1587-1590 - "oral glucosamine supplementation does not result in clinically significant alterations in glucose metabolism in patients with type 2 diabetes mellitus"
• Ginseng May Improve Glucose Control - Doctor's Guide, 6/18/03
• Coffee May Help Prevent Diabetes - WebMD, 6/18/03
• Coffee May Cut Diabetes Risk - Medscape, 6/18/03 - "Men who drink six or more cups of coffee a day were less than half as likely to develop diabetes compared with nondrinkers. Drinking four to six cups helps too: Those men saw their risk cut by 29% ... Women who consume four cups or more a day also reduced their risk of developing the disease by about 30%. But in their case, six cups did not seem to be any more protective than four cups ... Decaf was associated with a "modest reduction" in risk for those who drank four cups or more a day"
• Ginseng May Help Treat Diabetes - WebMD, 6/16/03 - "There are two reasons blood sugar can be out of control in [people with diabetes] ... Your body's tissues are not responsive enough to insulin so they don't process it properly and/or you don't make enough insulin to begin with ... Ginseng, he said, appears to help the patients both to secrete more insulin and to process better the insulin they have" - See iHerb or Vitacost American ginseng products.
• Magnesium Deficiency Associated with Insulin-Resistance Syndrome - New Hope Natural Media, 6/12/03
• Light Drinking May Cut Diabetes Risk - Intelihealth, 6/10/03 - "women who had about half a drink to two drinks a day were 58 percent less likely than nondrinkers to develop type 2 diabetes ... those who had more than two drinks of hard liquor a day faced more than double the risk of nondrinkers ... Small amounts of alcohol are believed to help the body make better use of insulin"
• Laughing After Meal Lowers Blood Sugar Levels Naturally - Doctor's Guide, 5/28/03
• Effects of eicosapentaenoic acid on platelet activation markers and cell adhesion molecules in hyperlipidemic patients with Type 2 diabetes mellitus - J Diabetes Complications 2003 May;17(3):153-159 - "After treatment with eicosapentaenoic acid (EPA), the levels of CD62P, CD63, annexin V, PDMPs, and MDMPs, sE-selectin, and oxidized LDL antibody were reduced significantly. Triglyceride (TG) and total cholesterol levels were also decreased. Anti-Ox LDL antibodies and MDMPs were correlated positively with platelet CD62P (plt-CD62P) levels. These findings suggest that in hyperlipidemic patients with Type 2 diabetes, EPA may prevent complications caused by oxidized LDL, E-selectin, and activated platelets or monocytes" - See Mega Twin EPA at Vitacost or iHerb.
• Multiple Vitamin and Mineral Supplement Prevents Infections in Diabetics - New Hope Natural Media, 5/8/03
• Moderate Physical Activity Lowers Diabetes Heart Risks - WebMD, 4/28/03
• Green Tea Supplement May Delay Diabetes - WebMD, 4/16/03
• A Derivative Of The Green Tea Leaf May Help With Metabolic Syndrome X, A Potentially Deadly Disorder - Intelihealth, 4/10/03 - "A new weapon might eventually be added to the arsenal: consumption of Tegreen, a tea polyphenols product containing in excess of 65 percent tea catechins, derived from the green tea leaf ... oral administration of Tegreen is capable of improving glucose and lipid metabolisms in an obese rat model induced by a high-calorie diet ... Tegreen intervention can significantly decrease visceral fat depot and increase the insulin's sensitivity, presumably touching one of the pathological root causes of this potentially deadly syndrome" - See iHerb or Vitacost green tea extracts.
• Oral Magnesium Supplementation Improves Insulin Sensitivity and Metabolic Control in Type 2 Diabetic Subjects: A randomized double-blind controlled trial - Diabetes Care 2003 Apr;26(4):1147-52 - "At the end of the study, subjects who received magnesium supplementation showed ... fasting glucose levels (8.0 +/- 2.4 vs. 10.3 +/- 2.1 mmol/l ... Oral supplementation with MgCl(2) solution restores serum magnesium levels, improving insulin sensitivity and metabolic control in type 2 diabetic patients with decreased serum magnesium levels" - See iHerb or Vitacost magnesium products.
• Eating Fish Lowers Heart Disease Risk in Women With Diabetes - WebMD, 3/31/03 - "It is believed that omega-3 fatty acids abundant in the fat of many fish reduces the risk of heart disease by lowering triglyceride levels, improving blood vessel function, and reducing blood-clot formation"
• Breakfast Reduces Diabetes, Heart Disease - WebMD, 3/6/03 - "A daily breakfast may reduce the risk of becoming obese or developing signs that can lead to diabetes -- called insulin resistance syndrome -- by 35% to 50% compared with skipping the morning meal ... Their recommendation: A bowl of whole-grain cereal ... eating whole-grain cereal each day was associated with a 15% reduction in risk for the insulin resistance syndrome ... soluble fiber forms a gel-like material that prevents cholesterol and saturated fats from entering the bloodstream, where they can collect and form plaques on artery walls. The insoluble fiber in these cereals, meanwhile, helps keep bowel movement regular and may help reduce risk of colon problems"
• Vitamins Reduce Rates of Colds and Other Infections for Those With Diabetes - WebMD, 3/3/03 - "Among all participants, 43% of those taking daily supplements reported getting sick during the study, compared with 73% of those getting a placebo. In those with diabetes, 93% taking a placebo got sick, compared with only 17% on the active supplements. However, in those without diabetes, there was no measurable difference between supplement- and placebo-takers ... the diabetics were recruited from an inner-city diabetes clinic, while those without the disease came from a middle-class health clinic and generally ate more nutritiously and were less likely to be obese"
• Whole-grain and fiber intake and the incidence of type 2 diabetes - AJCN, 3/1/03 - "Whole-grain consumption was associated with a reduced risk of type 2 diabetes. The relative risk (adjusted for age, sex, geographic area, smoking status, body mass index, energy intake, and intakes of vegetables, fruit, and berries) between the highest and lowest quartiles of whole-grain consumption was 0.65 (95% CI: 0.36, 1.18; P for trend = 0.02). Cereal fiber intake was also associated with a reduced risk of type 2 diabetes. The relative risk between the extreme quartiles of cereal fiber intake was 0.39" - [WebMD]
• Prevent and Reverse Diabetes with Proper Nutrition - Vitacost Newsletter, 2/20/03
• Is Type 1 Diabetes an Environmental Disease? - Dr. Murray's Newsletter, 2/5/03
• Shining a Light on the Health Benefits of Vitamin D - New York Times, 1/28/03 - "vitamin D deficiency has been associated with an increased risk for Type 1 diabetes. The converse is also true. Adequate vitamin D equals less risk for diabetes"
• Vitamins C and E may enhance effectiveness of insulin for diabetes - University of California at Irvine, 1/29/03 - "Boosting insulin with vitamins C and E may improve the drug's effectiveness for treating diabetes ... the popular antioxidant supplements not only enhance insulin's ability to reduce blood sugar, but also lower the risks of organ damage that can occur despite insulin treatments"
• Whole Grain Intake Reduces Risk of Type 2 Diabetes in Men - New Hope Natural Media, 12/26/02 - "People who consumed the highest amount of whole grains (3.2 servings per day) had a 30% to 40% reduction in risk of developing type 2 diabetes compared with those who ate less than 1 serving a day ... The benefits of whole grains may be due to their increased content of fiber, which is mostly removed in process of refining whole grains to white flour. However, some studies suggest that the higher amount of magnesium in whole grains also contributes to the lower risk of diabetes"
• Nuts, Peanut Butter Consumption Associated with Lower Diabetes Risk in Women - Doctor's Guide, 11/28/02
• Peanut Butter, Nuts Lower Diabetes Risk - WebMD, 11/26/02 - "Women who reported eating a tablespoon of peanut butter at least five times a week had a 21% reduced risk of type 2 diabetes compared to those who rarely or never ate it ... A 27% decrease was noted in women who consumed five ounces of nuts each week compared to women who never or almost never consumed nuts ... That handful of nuts also contains about 170 calories ... urge that regular peanut butter and nut consumption be used as its original intention -- as a replacement for meat and other foods, not in addition to them"
• Niacin Appears Safe for Treating Patients Who Have Diabetes and High Cholesterol - Doctor's Guide, 11/21/02
• Soy Beneficial for Postmenopausal Women with Type 2 Diabetes - New Hope Natural Media, 11/14/02
• High Coffee Intake May Lower Type 2 Diabetes Risk - Doctor's Guide, 11/7/02
• Java Reduces Type 2 Diabetes Risk - WebMD, 11/7/02 - "Caffeine is known to decrease the body's response to insulin. However, other ingredients found in coffee -- magnesium and chlorogenic acid -- may have beneficial effects ... researchers followed more than 17,000 Dutch adults. After several years of follow-up, those who drank seven or more cups a day were half as likely to develop type 2 diabetes compared with those who drank less than two cups a day ... The long-term effects of drinking too much caffeine are not known and other health issues could develop" - Note:  Chlorogenic acid is in artichoke extract.  If magnesium and chlorogenic acid are the reason for the 50% diabetes reduction, it would seem to be a better choice than drinking seven cups of coffee per day.  See iHerb or Vitacost artichoke products. - Ben
• Soy Helps Hearts for Some Diabetics - WebMD, 10/4/02
• Fish Oil May Augment Atorvastatin As Treatment For Dyslipidemia In Obese, Insulin-Resistant Men - Doctor's Guide, 8/7/02 - "fish oils significantly decreased plasma levels of triglycerides and very low density lipoprotein-apoB, decreased the very low density lipoprotein-apoB secretion rate ... combined treatment with atorvastatin and fish oils decreased very low density lipoprotein-apoB secretion and increased the fractional catabolic rate of apoB in each lipoprotein fraction , as well as the percent conversion of very low density lipoprotein to low density lipoprotein" - See Mega Twin EPA at iHerb or Vitacost.
• Ginseng May Help Regulate Blood Glucose - Natural Foods Merchandiser, 8/02 - "Three new studies, performed jointly by researchers at the University of Toronto, St. Michael's Hospital in Toronto and the University of Ottawa, show that American ginseng can lower blood-sugar levels in diabetic and nondiabetic patients" - See iHerb and Vitacost American ginseng products.
• Novel Method of Enhancing Anti-Fat Effects of CLA - Life Extension Magazine, 8/02 - "CLA improves insulin sensitivity" - See iHerb or Vitacost CLA products.
• The Benefits of Carnitine and DHEA for Fat Metabolism - Life Extension Magazine, 8/02 - "Carnitine is an amino acid that's critical for converting fatty acids into fuel. Because of this, it has the potential to help people lose weight ... A lack of DHEA may be one of the primary causes of insulin resistance"
• Folate Supplements May Help Restore Endothelial Function In Type 2 Diabetics - Doctor's Guide, 8/1/02
• Want to Reduce Your Diabetes Risk? - WebMD, 7/25/02 - "those who reported eating the most servings of whole grain foods tended to have lower insulin levels, lower body weights, and lower cholesterol levels ... The study is just the latest to find that foods such as slow-cooking oatmeal, popcorn, brown rice, and certain processed whole grain breads and cereals are protective against type 2 diabetes. Eating whole grain foods has also been shown to lower the risk of cardiovascular disease ... the wildly popular weight-loss programs that restrict or eliminate carbohydrates from the diet are delivering the false message that all carbohydrates are bad"
• Niacin May Be Effective Therapy For Broad Range Of Diabetes-Associated Dyslipidaemias - Doctor's Guide, 7/25/02 - "After niacin treatment, the patients' LDL peak particle diameter increased from 252 ± 7 Å to 263 ± 7, the researchers reported. Their small, dense LDLc particle mass decreased from 27 ± 11 mg/dL to 15 ± 4 mg/dL. Total HDLc increased from 39 ± 7 mg/dL to 51 ± 11 mg/dL. Their HDL2, as the percentage of total HDLc mass, increased from 29 ± 8 percent to 45 ± 10 percent, and their Lp(a) decreased from 43 ± 17 mg/dL to 25 ± 10 mg/dL ... Twenty-one percent of the patients were unable to tolerate niacin because of reversible adverse effects. Another 14 percent were unable to adhere to the niacin dosing regimen of three times daily"
• Higher Folate Levels May Help Protect Against Vascular Disease in Children with Diabetes - Doctor's Guide, 7/18/02 - "High folate levels may protect children with type I diabetes from vascular damage"
• Soy Comparable to Some Diabetes Drugs - WebMD, 6/20/02 - "Soy may help people with diabetes control their blood sugar as well as some prescription drugs ... One group sprinkled their food daily with a white powder containing 30 grams of soy protein and 132 milligrams of soy isoflavones for 12 weeks ... The soy products lowered the women's blood sugar as much as some prescription diabetes drugs"
• Nuts May Lower Risk of Diabetes - Medscape, 6/19/02 - "New data presented June 16-17 at the 62nd Scientific Sessions of the American Diabetes Association suggest that eating nuts helps prevent the development of diabetes and that zinc supplementation in obese, insulin-resistant women improves insulin sensitivity, even in the absence of zinc deficiency ... In this prospective, double-blind, clinical interventional study, 56 obese women with normal glucose tolerance were randomized to treatment with zinc, 30 mg daily, or placebo for four weeks ... Insulin resistance as measured by a homeostasis model assessment did not change in the placebo group, but it decreased from 5.8 ± 2.6 to 4.3 ± 1.7 (P<.05) in the zinc-supplemented group. Insulin decreased from 28.8 ± 14.1 to 21.2 ± 8.1 mU/mL (P<.05) in the zinc group but was unchanged in the placebo group"
• Soy Supplements May Help Control Blood Sugar - Intelihealth, 6/17/02 - "After 12 weeks, the women taking the soy supplement showed significantly better control over their blood sugar, according to several standard tests, and their levels of total cholesterol and low-density lipoprotein (so-called "bad cholesterol") dropped"
• New styles help diabetics cook up a healthy balance - USA Today, 6/12/02
• Insulin Sensitivity Increases with Physical Exercise in Hypertensive Subjects - Doctor's Guide, 5/24/02
• Moderate Drinking Increases Insulin Sensitivity In Non-Diabetic, Older Women - Doctor's Guide, 5/16/02 - "Moderate alcohol consumption reduces insulin and triglyceride concentrations and increases insulin sensitivity in nondiabetic, postmenopausal women ... the changes they observed may reduce the risk of developing type 2 diabetes and cardiovascular disease in this population of women ... Researchers warn, however, that the alcohol intake significantly increased serum levels of dehydroepiandrosterone sulphate and estrone sulphate, steroid hormones known to be risk factors for breast cancer"
• Putting Antioxidants To Use In Functional Formulas - Functional Foods & Nutraceuticals, 5/02 - "Clinical studies have found that it can improve insulin function, helping to improve glucose tolerance in people with diabetes.15,16 Some researchers have suggested that long-term use of alpha-lipoic acid may help prevent adult-onset diabetes"
• Dairy Foods Linked to Less Type 2 Diabetes - WebMD, 4/23/02
• New Evidence That Dietary Soy And Flaxseed Have Positive Effect On Obesity And Diabetes - Intelihealth, 4/22/02 - "These data suggest that diets rich in soy protein and flaxseed have beneficial effects on many aspects of obesity and diabetes"
• Rice Bran Lowers Diabetic Blood Sugar - WebMD, 4/10/02 - "Rice bran was able to lower blood glucose by up to 30% in a small group of patients with type 1 or 2 diabetes ... also found that patients with elevated cholesterol who consumed 20 grams per day of stabilized rice bran lowered their total serum cholesterol and triglyceride levels between 5% and 15%"
• Ginseng Helps Regulate Blood Glucose - Nutrition Science News, Spring '02 - "Three new studies, performed jointly by researchers at the University of Toronto, St. Michael's Hospital in Toronto, and the University of Ottawa, show that American ginseng can lower blood-sugar levels in diabetic and nondiabetic patients ... They found no significant differences between the three doses—each lowered postprandial glucose levels an average of 11.4 percent"
• Diet And Exercise More Effective Than Medication For Prevention Of Type 2 Diabetes - Intelihealth, 2/7/02
• How to Stop Diabetes In Its Tracks - WebMD, 2/6/02 - "the study found that the diet/exercise program cut diabetes risk by 58%. Glucophage was significantly less effective, but still decreased risk by 31% ... The diet was centered around lowering fat intake to less than 25% of overall calories ... the 30-minute daily exercise regime "should be easily achievable" by most nondiabetic overweight Americans with high blood sugar levels"
• Hey Guys: The Right Diet Averts Diabetes - WebMD, 2/4/02
• Adequate Magnesium Intake Reduces Risk For Cardiovascular Disease Type 1 Diabetics - Doctor's Guide, 1/18/02
• Stress Reduction May Improve Blood Sugar Levels In Type 2 Diabetes Patients - Intelihealth, 1/10/02
• Controlling Diabetes the Natural Way - Life Extension Magazine, 12/00
• Vitamin D Supplementation During Infancy Reduces Risk Of Type 1 Diabetes - Intelihealth, 11/8/01 - "Those who regularly took at least the recommended dose of vitamin D (2000 IU daily) during their first year of life had an 80% reduced risk of type 1 diabetes compared to those who received less than the recommended amount"
• Vitamin D Supplements May Protect Against Diabetes in Kids - WebMD, 11/1/01 - "giving vitamin D supplements to children may help protect them from high blood sugar ... Children who had the recommended supplements of vitamin D (usually in the form of cod-liver oil) were found to have an 80% reduction in diabetes risk, compared to those receiving less than the recommended dose"
• You Can Take Control of Your Diabetes - WebMD, 10/25/01
• Can a Mix of Chromium and Biotin Help Diabetics Control Blood Sugar? - WebMD, 10/15/01
• Healthy Living May Stop Diabetes - Intelihealth, 9/24/01
• Healthy Lifestyle, Healthy Weight Can Prevent Type 2 Diabetes - WebMD, 9/20/01
• Vanadium: The Blue Mineral for Diabetes - Nutrition Science News, 9/01
• Diets Rich in Vegetable Fat May Prevent Diabetes - WebMD, 8/24/01 - "those women who consumed the highest amounts of vegetable fat -- 41.7 grams per day -- had a 22% lower risk of developing type 2 diabetes than their counterparts who consumed the least amount of such fats ... women who traded animal fat or saturated fat for the type found mainly in vegetable oils such as safflower, sunflower, corn, flaxseed, canola oils, and fish lowered their risk of type 2 diabetes by about 16%"
• Diet And Exercise Cut Risk Of Type 2 Diabetes In Half - Intelihealth, 8/16/01 - "Americans who are at high risk for type 2 diabetes can reduce their risk of developing the condition by more than half with a daily regimen of diet and exercise"
• Diet High in Veggies Can Reverse Type 2 Diabetes - WebMD, 7/12/01 - "After six months, levels of hemoglobin A1C -- which reveal how high the blood sugar has been over a period of several weeks -- were an average of 30% lower in the 31 patients who stuck with the diet. Also, their total cholesterol and "bad" LDL cholesterol dropped nearly one-third, while their "good" HDL cholesterol increased 10%"
• Could Nicotinamide And Vitamin E Have Synergistic Effect And Reduce Insulin Usage? - Doctor's Guide, 7/11/01 - "The combination of nicotinamide and vitamin E might have a synergistic effect in lowering daily insulin usage among newly diagnosed Type 1 diabetics"
• Sleep on This: Lack of Shut-Eye Ups Diabetes Risk - WebMD, 6/25/01 - "People who don't get adequate rest may increase their risk for type 2 diabetes ... "short-sleepers," or those who slept less than 6.5 hours per night, were about 40% less insulin-sensitive than normal sleepers, those who logged about 7.5 to 8.5 hours a night"
• Type 2 Diabetics Benefit From Reducing Intake Of Animal Protein - Doctor's Guide, 6/21/01
• News - Polyunsaturated Fatty Acids Reduce Women's Risk Of Type 2 Diabetes - Doctor's Guide, 5/31/01 - "Trans fatty acids increase the risk of type 2 diabetes in women, while polyunsaturated fatty acids reduce that risk"
• Type 2 Diabetes Is Preventable, Eating Right, Exercise Reduces Prevents Diabetes - WebMD, 5/2/01
• Study: Diet changes, exercise can prevent diabetes - USA Today, 5/2/01
• Stress: The Hidden Factor For Weight Gain - Nutrition Science News, 4/01 - "Under stress, the body excretes corticotrophin-releasing hormone and adrenalin. This reaction stimulates the release of cortisol from the adrenal cortex. In turn, cortisol, a glucocorticoid, stimulates glucose release into the bloodstream, which, during periods of chronic stress, creates an excessive release of insulin. Insulin, which is part of the endocrine system, is a fat-storage hormone that overrides the stress signal from adrenalin to burn fat. The excess release of insulin gives the body the message to store fat in the abdomen"
• The Prediabetic Epidemic - Nutrition Science News, 3/01 - "Supplements to Regulate Glucose and Insulin ... Alpha-Lipoic Acid ... Vitamin E ... Vitamin C ... Chromium ... Silymarin"
• Soy Story: Can Supplements Help Diabetics Avoid Heart Disease? - WebMD, 2/21/01 - "patients' cholesterol levels were significantly lower after the six weeks of soy supplements than it was when measured after taking the inactive placebo drug. Among their findings: LDL or "bad cholesterol" levels decreased significantly with the soy"
• Vitamins C and E May Reduce Risk, Complications of Diabetes - WebMD, 11/15/00 - "Anderson's extensive research with vitamin E has led him to believe that the benefits of taking antioxidants is so favorable, that all adults should take 800 IU of vitamin E as a preventive measure ... it not only functions as an antioxidant, but anti-inflammatory [as well] ... Most evidence suggests a higher fiber diet rich in whole grains, fruits, and vegetables, and lower fat"
• Niaspan (Niacin Extended Release Tablets) Safe And Effective For Diabetics - Doctor's Guide, 11/14/00 - "Niaspan [extended release niacin] therapy increased HDL up to 24 percent and decreased triglycerides as much as 30 percent"
• Some Diabetics Buck Tradition and Turn to Herbs - WebMD, 10/9/00 - "Researchers have submitted study results to the journal Diabetes Care for another natural product -- alpha lipoic acid, known by the brand name Glucotize. The product "lowers blood sugar levels, which is excellent," ... "Because that's what causes a lot of diabetic complications.""
• Lipoic Acid: The Universal Antioxidant - Nutrition Science News, 10/00 - "Like other antioxidants, lipoic acid has the ability to scavenge the body for disease-causing free radicals; however, that appears to only scratch the surface of this supplement's benefits ... Free radical scavenging ... Metal chelation ... Antioxidant regeneration ... Damaged molecule repair ... Atherosclerosis protection ... Cataract protection ... Protection against irradiation ... HIV treatment ... Diabetes therapy"
• Diabetic Kids May Benefit From Daily Vitamin E - WebMD, 9/26/00 - "when children were given vitamin E supplements each day, in a relatively small dose of 100 IU per day for three months, levels of glutathione increased. This is good news because glutathione provides natural protection against the toxic effects of free radicals, the body's natural but harmful byproducts of daily living that damage cells. Glutathione levels can be low in diabetics, and diabetics are also more susceptible to damage from these substances. Free radicals have also been implicated in other diseases including hardening of the arteries, cataracts, Parkinson's disease, and Alzheimer's disease"
• Can Cod Liver Oil Help Prevent Diabetes? - WebMD, 9/22/00
• Niacin Is Safe for Diabetics With High Cholesterol, Study Shows - WebMD, 9/12/00
• E Gets an 'A' at Lowering Risk of Diabetes Complications - WebMD, 7/11/00
• Vitamin E Works As Anti-Inflammatory Agent In Type II Diabetes - Doctor's Guide, 7/10/00 - "A high intake of vitamin E can help reduce heart disease and stroke risk in type II diabetics"
• Could Eating Certain Types of Fat Help Teens Control Diabetes? - WebMD, 7/5/00
• Glucosamine a New Concern for Diabetes - Nutrition Science News, 6/00
• More Fiber, Less Diabetes Medicine? - WebMD, 5/10/00
• Study Tests Diabetes Prevention - Intelihealth, 12/31/99
• Low Magnesium Levels May Strongly Foreshadow Diabetes Development in Whites - WebMD, 10/18/99
• Silicone Injections Protect Diabetics' Feet - Doctor's Guide, 6/21/99
• Diabetics Improve Health With Very High-Fat, Low Carb Diet - Doctor's Guide, 6/15/99
• Chromax Effective For Steroid-Induced Diabetes Treatment - Doctor's Guide, 3/26/99
• Chromium Steels the Body Against Diabetes - Nutrition Science News, 2/99
• Antioxidants May Reduce Harmful Complications Of Diabetes - Doctor's Guide, 4/20/98
• Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat - Biochem Biophys Res Commun. 1998 Mar 27;244(3):678-82 - "CLA effects on glucose tolerance and glucose homeostasis indicate that dietary CLA may prove to be an important therapy for the prevention and treatment of NIDDM."
• Chromium May Help Obese People Avoid Diabetes - Doctor's Guide, 6/30/97
• Alpha Lipoic Acid For Diabetes, Atherosclerosis And Aging - Life Extension Magazine, 3/96

CME/CEM:

• Medscape diabetes CME courses
• Doctor's Guide diabetes CME courses
• The Role of Insulin in the Management of Type 2 Diabetes - PowerPak.com, exp. 1/1/05
• Contemporary Issues in Type 2 Diabetes Therapy - PowerPak.com, exp. 12/1/05
• Lower Extremity Skin Care for the Diabetic Patient - PowerPak.com, exp. 11/1/04
• Managing the Diabetic Patient - American College of Physicians

General Information:

• Diabetes - American Academy of Family Physicians
• Diabetes - emedicine.com
• Diabetes - familydoctor.org
• Diabetes - Intelihealth
• Diabetes - Veritas Medicine
• High-Carbohydrate Diet May Increase Blood Pressure in Patients With Type 2 Diabetes - Medscape, exp., 11/1/06
• Achieving Glycemic Control in Type 2 Diabetes - Medscape, 12/3/04
• Differentiating Between Type 1 and Type 2 Diabetes - Medscape, 2/27/03
• Diabetes Health Center - Discovery.com
• Books on diabetes - Amazon.com
• Treatments for diabetes - Medifocus.com

Other News:

• Diabetes shrinks elderly brain - Science Daily, 5/7/12 - "While some brain volume loss is a normal part of aging, the researchers found that elderly people with blood sugar levels in flux, as well as type 2 diabetes, lost almost two and a half times more brain volume than their peers over two years. The reduction in size of the frontal lobe -- associated with higher mental functions like decision-making, emotional control, and long term memory -- has a significant impact on cognitive function and quality of life"
• Kids With Type 2 Diabetes: Combo Treatment Best? - WebMD, 4/29/12 - "Combined treatment with the diabetes drugs metformin and Avandia proved more effective than metformin alone or metformin plus lifestyle changes for keeping blood sugar at normal levels ... 38% of patients who took metformin and Avandia failed treatment ... 46% of patients in the metformin and lifestyle part of the study failed treatment" - Note:  That was the combo I picked years ago for diabetes prevention even though I don't have diabetes.  See Avandia (rosiglitazone) at OffshoreRx.com.
• High levels of phthalates can lead to greater risk for type-2 diabetes - Science Daily, 4/12/12 - "There is a connection between phthalates found in cosmetics and plastics and the risk of developing diabetes among seniors. Even at a modest increase in circulating phthalate levels, the risk of diabetes is doubled ... Most people come into daily contact with phthalates as they are used a softening agents in plastics and as carriers of perfumes in cosmetics and self-care products"
• Periodontal Treatment Cost Effective for Diabetics - Medscape, 3/27/12 - "Patients with diabetes who are treated for periodontal disease are less likely to see a physician and less likely to be hospitalized. Furthermore, they cost the healthcare system $1800 less per patient per year ... There was a 33% reduction in the number of hospitalizations with treatment; the mean number of hospitalizations was 5.9 in the treatment group and 9.0 in the control group ... There was a savings of $1814 (or 25%) with treatment; mean medical cost was $5522 in the treatment group and $7336 per year in the control group"
• Statins linked to higher diabetes risk  - USATODAY.com, 1/9/12 - "Study authors advise patients not to stop taking their medications without talking to a doctor, because statins' proven power to prevent heart attacks and strokes outweighs any potential increase in type 2 diabetes risk. But the results — a nearly 50% increase in diabetes among longtime statin users — should throw cold water on the idea of prescribing these drugs to healthy people, which some have recommended as a way to prevent disease ... In the study, 6.4% of women who didn't use statins developed diabetes during the eight to nine years of follow-up ... That rate rose to 9.9% among statin users"
• Diabetes linked to cognitive impairment in older adults, study suggests - Science Daily, 11/8/11 - "in older patients with diabetes, two adhesion molecules -- sVCAM and sICAM -- cause inflammation in the brain, triggering a series of events that affect blood vessels and, eventually, cause brain tissue to atrophy. Importantly, they found that the gray matter in the brain's frontal and temporal regions -- responsible for such critical functions as decision-making, language, verbal memory and complex tasks -- is the area most affected by these events ... at the age of 65, the average person's brain shrinks about one percent a year, but in a diabetic patient, brain volume can be lowered by as much as 15 percent ... Diabetes develops when glucose builds up in the blood instead of entering the body's cells to be used as energy. Known as hyperglycemia, this condition often goes hand-in-hand with inflammation ... Once chronic inflammation sets in, blood vessels constrict, blood flow is reduced, and brain tissue is damaged"
• Diabetes may significantly increase the risk of dementia - Science Daily, 9/19/11 - "people with diabetes were twice as likely to develop dementia as people with normal blood sugar levels ... the risk of developing dementia significantly increased when blood sugar was still high two hours after a meal"
• Weight loss improves sexual health of overweight men with diabetes, study finds - Science Daily, 8/5/11
• Insomnia linked to high insulin resistance in diabetics - Science Daily, 5/2/11 - "Among the diabetics, poor sleepers had 23% higher blood glucose levels in the morning, and 48% higher blood insulin levels. Using these numbers to estimate a person's insulin resistance, the researchers found that poor sleepers with diabetes had 82% higher insulin resistance than normal sleepers with diabetes"
• Increase in deaths in men with type 2 diabetes and testosterone deficiency may be prevented by testosterone replacement, study suggests - Science Daily, 4/12/11 - "conducted a six year study of 587 men with type 2 diabetes, splitting them into three groups: those with normal total testosterone levels (above 10.4nmol/L, n=338), those with low testosterone levels (below 10.4nmol/L) that weren't treated with testosterone replacement therapy (n=182), and those with low testosterone levels treated with testosterone replacement therapy for two years or more during the follow up period (n=58) ... The findings show for the first time that low testosterone puts diabetic men at a significantly increased risk of death (p=0.001 log rank): 36 of the 182 diabetic men with untreated low testosterone died during the six year study, compared to 31 of the 338 men with normal testosterone levels (20% vs 9%). Furthermore, only 5 of the 58 diabetic men that were given testosterone replacement therapy died during the study (8.6%), meaning they showed significantly better survival compared to the non-treated group (p=0.049 log rank) ... In the 356 men with type 2 diabetes tested, health related quality of life decreased as testosterone levels decreased (r=0.353 p=0.044)"
• Treating high blood pressure, cholesterol, diabetes may lower risk of Alzheimer's disease - Science Daily, 4/13/11 - "After five years, 298 people developed Alzheimer's disease. The others still had mild cognitive impairment. People with risk factors such as high blood pressure, diabetes, cerebrovascular disease and high cholesterol were two times more likely to develop Alzheimer's disease than those without vascular risk factors. A total of 52 percent of those with risk factors developed Alzheimer's disease, compared to 36 percent of those with no risk factors ... Of those with vascular risk factors, people who were receiving full treatment were 39 percent less likely to develop Alzheimer's disease than those receiving no treatment. Those receiving some treatments were 26 percent less likely to develop the disease compared to people who did not receive any treatment ... Although this was not a controlled trial, patients who were treated for their high blood pressure, high cholesterol, heart disease and diabetes had less progression of their memory or thinking impairment and were less likely to develop dementia"
• Avoiding or controlling diabetes may reduce cancer risk and mortality - Science Daily, 4/3/11 - "Previous epidemiologic studies have shown an association between diabetes and an increased risk for cancers including colorectal, liver and pancreas ... As for mortality, diabetes was associated with an 11 percent increased risk in women and a 17 percent increased risk in men ... diabetes was associated with a significant increase in risk for colon, rectal and liver cancers among men and women. In men, diabetes was associated with an increased risk for pancreatic and bladder cancers; in women, it was associated with an increased risk for stomach, anal and endometrial cancers. No association was found between diabetes and lung, skin or other cancers"
• The Association Between Dietary Sodium Intake, ESRD, and All-Cause Mortality In Patients With Type 1 Diabetes - Diabetes Care. 2011 Feb 9 - "Many guidelines recommend reduced consumption of salt in patients with type 1 diabetes, but it is unclear whether dietary sodium intake is associated with mortality and end-stage renal disease (ESRD) ... The median follow-up for survival analyses was 10 years, during which 217 deaths were recorded (7.7%). Urinary sodium excretion was nonlinearly associated with all-cause mortality, such that individuals with the highest daily urinary sodium excretion, as well as the lowest excretion, had reduced survival. This association was independent age, sex, duration of diabetes, the presence and severity of chronic kidney disease (CKD) (estimated glomerular filtration rate [eGFR] and log AER), the presence of established cardiovascular disease, and systolic blood pressure. During follow-up 126 patients developed ESRD (4.5%). Urinary sodium excretion was inversely associated with the cumulative incidence of ESRD, such that individuals with the lowest sodium excretion had the highest cumulative incidence of ESRD. CONCLUSIONS In patients with type 1 diabetes, sodium was independently associated all-cause mortality and ESRD. Although we have not demonstrated causality, these findings support the calls for caution before applying salt restriction universally. Clinical trials must be performed in diabetic patients to formally test the utility/risk of sodium restriction in this setting"
• Association Between Periodontitis and Impaired Fasting Glucose and Diabetes - Diabetes Care. 2011 Jan 7 - "clinical attachment loss (CAL) ... Participants in the top quintile category of CAL had higher prevalence odds of IFG (odds ratio [OR] 1.55 [95% CI 1.16-2.07]) and diabetes (4.77 [2.69-8.46]) after adjustment for related confounders, compared with those in the bottom quintile. The highest quintile of pocket depth was positively associated with IFG (1.39 [1.00-1.92]) and diabetes (1.63 [1.10-2.42]) compared with the lowest quintile. ORs for CAL increased from the lowest to the highest quintile (P value test for trend <0.01) for all outcomes. The ORs for pocket depth also tended to rise across quintiles. CONCLUSIONS Chronic periodontitis measured by CAL and pocket depth was positively associated in a linear relation with IFG and diabetes in U.S. adults"
• Inhibition of the receptor for advanced glycation endproducts (RAGE) protects pancreatic β-cells - Biochem Biophys Res Commun. 2010 Nov 24 - "Advanced glycation endproducts (AGEs) and the receptor for AGEs (RAGE) have been linked to the pathogenesis of diabetic complications, such as retinopathy, neuropathy, and nephropathy. AGEs may induce β-cell dysfunction and apoptosis, another complication of diabetes ... Inhibition of RAGE prevented AGE-induced pancreatic β-cell apoptosis, but could not restore the function of glucose stimulated insulin secretion (GSIS) in rat islets. In summary, the results of the present study demonstrate that AGEs are integrally involved in RAGE-mediated apoptosis and impaired GSIS dysfunction in pancreatic β-cells. Inhibition of RAGE can effectively protect β-cells against AGE-induced apoptosis, but can not reverse islet dysfunction in GSIS"
• Diabetes may affect as many as 1 in 3 Americans by 2050 - USA Today, 10/21/10 - "one in 10 U.S. adults have diabetes now. The prevalence is expected to rise sharply over the next 40 years with as many as one in three having the disease, primarily type 2 diabetes, according to the report" - Note:  I believe that's the main reason life expectancy in the U.S. isn't that impressive.  Americans do not get enough exercise and they overeat. The portion size at restaurants is three times that of some countries I've been to.  Exercise also slows the rate of loss of telomere shortening.  Longer telomeres is associated with longevity.
• Insulin resistance, type 2 diabetes linked to plaques associated with Alzheimer's disease - Science Daily, 8/25/10 - "People with insulin resistance and type 2 diabetes appear to be at an increased risk of developing plaques in the brain that are associated with Alzheimer's disease ... people who had abnormal results on three tests of blood sugar control had an increased risk of developing plaques. Plaques were found in 72 percent of people with insulin resistance and 62 percent of people with no indication of insulin resistance" - [Abstract]
• Experts explore emerging evidence linking diabetes and cancer - Science Daily, 6/16/10 - "Possible mechanisms for a direct link between diabetes and cancer include hyperinsulinemia, hyperglycemia, and inflammation"
• Eating processed meats, but not unprocessed red meats, may raise risk of heart disease and diabetes, study finds - Science Daily, 5/17/10 - "eating processed meat, such as bacon, sausage or processed deli meats, was associated with a 42% higher risk of heart disease and a 19% higher risk of type 2 diabetes. In contrast, the researchers did not find any higher risk of heart disease or diabetes among individuals eating unprocessed red meat, such as from beef, pork, or lamb"
• Drinking sugar-sweetened beverages daily linked to diabetes - Science Daily, 3/6/10 - "Using the Coronary Heart Disease (CHD) Policy Model, a well-established computer simulation model of the national population age 35 and older, researchers estimate that the increased consumption of sugar-sweetened beverages between 1990 and 2000 contributed to 130,000 new cases of diabetes, 14,000 new cases of coronary heart disease (CHD), and 50,000 additional life-years burdened by coronary heart disease over the past decade"
• Hemoglobin A1c outperforms fasting glucose for risk prediction - Science Daily, 3/3/10 - "Measurements of hemoglobin A1c (HbA1c) more accurately identify persons at risk for clinical outcomes than the commonly used measurement of fasting glucose ... people with HbA1c levels between 5.0 to 5.5 percent were identified as being within "normal" range ... With each incremental HbA1c increase, the study found, the incidence of diabetes increased as well; those at a level of 6.5 percent or greater are considered diabetic, and those between 6.0 and 6.5 percent are considered at a "very high risk" (9 times greater than those at the "normal" range) for developing diabetes"
• Insulin used to treat diabetes may be linked to increased cancer risk, review suggests - Science Daily, 3/2/10 - "Research suggests that metformin, which is used to treat some patients with diabetes, may provide a protective effect, while insulin and/or certain insulin analogues may promote tumour growth ... Diabetic patients were 30 per cent more likely to develop colorectal cancer ... Women with diabetes had a 20 per cent greater risk of developing breast cancer ... People with diabetes had an 82 per cent higher risk of developing pancreatic cancer" -  Note:  See my Insulin and Aging page.  I think it's like what came first the chicken or the egg.  I don't believe they know whether it's the insulin or the high blood sugar.  This seems to support that it's the high insulin.
• Diabetes Accelerates Conversion of Mild Cognitive Impairment to Dementia - Medscape, 1/11/10 - "Our study demonstrates that individuals with mild cognitive impairment and diabetes are at increased risk of developing dementia"
• Low testosterone levels and SHBG levels and high estradiol levels are independent predictors of type 2 diabetes in men - Eur J Endocrinol. 2010 Jan 8 - "There was a significantly lowered multi-adjusted risk for later diabetes with higher normal total testosterone levels, both linearly per SD increase (HR 0.71, CI 0.54-0.92) and in the higher quartiles of total testosterone compared to the lowest (HR 0.53, CI 0.33-0.84). A reduced multi-adjusted risk for incident diabetes was also found for men with higher SHBG levels, both linearly per SD increase (HR 0.55, CI 0.39-0.79) and when comparing the third (HR 0.38, CI 0.18-0.81) and the fourth quartile (HR 0.37, 0.17-0.82) to the lowest. The associations with total testosterone and SHBG were no longer significant after inclusion of waist circumference to the multivariate models. Estradiol was positively associated with incident diabetes after multivariate adjustments including waist circumference, when comparing the second (HR 0.49, CI 0.26-0.93) and the third (HR 0.51, CI 0.27-0.96) quartile to the highest Conclusion. Men with higher estradiol levels had an increased risk of later diabetes independent of obesity, while men with lower total testosterone and SHBG had an increased risk of diabetes that appeared dependent of obesity"
• Statins May Soon Be Given to Those With Excess Inflammation - U.S. News, 12/17/09 - "The Food and Drug Administration is considering expanding the use of cholesterol-lowering statin Crestor to those who have increased levels of inflammation—but not high cholesterol ... 2.8 percent of folks in the Crestor group developed diabetes compared with 2.3 percent of those who took placebos ... Experts still can't explain why Crestor would increase the likelihood of diabetes, but other research suggests that the entire class of statin drugs appears to have this downside ... found a 13 percent increased risk in diabetes in the statin users ... 1.5 percent of the placebo takers had a heart attack or stroke compared with 0.72 percent of the statin takers"
• More than 90 percent of people with gum disease are at risk for diabetes, study finds - Science Daily, 12/15/09 - "An overwhelming majority of people who have periodontal (gum) disease are also at high risk for diabetes and should be screened for diabetes ... 93 percent of subjects who had periodontal disease, compared to 63 percent of those without the disease, were considered to be at high risk for diabetes and should be screened for diabetes"
• Steroid injections may slow diabetes-related eye disease - Science Daily, 12/14/09
• Delaying Type 1 Diabetes - WebMD, 11/25/09
• Metformin associated with lower cancer mortality in type 2 diabetes (ZODIAC-16) - Diabetes Care. 2009 Nov 16 - "Median follow-up time was 9.6 years, average age at baseline was 68 years, and average HbA1c was 7.5%. Five hundred seventy patients died, of which 122 from malignancies. SMR for cancer mortality was 1.47 (95%CI 1.22-1.76). In patients taking metformin compared to patients not taking metformin at baseline, the adjusted hazard ratio (HR) for cancer mortality was 0.43 (95%CI 0.23-0.80), and the HR with every increase of 1 gram of metformin was 0.58 (95%CI 0.36-0.93) ... In general, patients with type 2 diabetes are at increased risk for cancer mortality. In our group, metformin use was associated with lower cancer mortality when compared to non-metformin use. Although the design cannot be conclusive about causality, our results suggest a protective effect of metformin on cancer mortality"
• Serum Uric Acid Linked With Development of Type 2 Diabetes - Science Daily, 10/2/09 - "The pooled crude relative risk (RR) of a 1 mg/dL increase in serum uric acid was 1.17"
• Low-Cost Drugs Prevent Heart Attack, Stroke - WebMD, 10/1/09 - "Besides being encouraged to take a daily aspirin, patients were prescribed a medication bundle, typically lovastatin (40 milligrams a day) to lower cholesterol and lisinopril (20 milligrams a day) to lower blood pressure ... Compared with the no-exposure group, the low-exposure group (whose members picked up medicines less than half the time) had a 60% reduction in hospitalizations for heart attack and stroke"
• Diabetes Weakens Your Bones - Science Daily, 9/28/09 - "They observed increased levels of inflammatory molecules, including TNF-α during fracture healing. The diabetic animals had rapid loss of cartilage in the healing bones, which was due to increased numbers of osteoclasts, cells that remove bone and cartilage. Factors that stimulate osteoclast formation were regulated by both TNF-α and a downstream mediator, FOXO1. These results suggest that diabetes-mediated increases in TNF-α and FOXO1 may underlie the impaired healing of diabetic fractures"
• Diabetes May Affect Women's Heart Rhythm - WebMD, 9/28/09
• New Sign of Diabetes Risk - WebMD, 9/16/09 - "People with the lowest SHBG levels have a tenfold higher risk of type 2 diabetes than those with the highest SHBG levels"
• Higher Levels of Adiponectin Associated With Lower Risk of Type 2 Diabetes - Doctor's Guide, 7/7/09 - "Although these epidemiologic studies cannot establish causality, the consistency of the association across diverse populations, the dose-response relationship, and the supportive findings in mechanistic studies indicate that adiponectin is a promising target for the reduction of risk of type 2 diabetes"
• How Obesity Increases The Risk For Diabetes - Science Daily, 6/21/09
• Pioglitazone Improves Endothelial Function with Increased Adiponectin and High-density Lipoprotein Cholesterol Levels in Type 2 Diabetes - Endocr J. 2009 Jun 9 - "After treatment, HbA1c levels equally decreased in both groups, but PIO-treated group had significantly increased high-density lipoprotein cholesterol (HDL-C) levels, and decreased triglyceride, fasting insulin levels and HOMA-R. After treatment, increases in %FMD, plasma HDL-C and adiponectin (APN) levels were significantly greater in PIO-treated group than those in control group. Changes of %FMD showed significant positive correlations with those of plasma APN and HDL-C levels. In conclusion, the present study showed that treatment of T2DM improved endothelial function with greater increases in %FMD, APN and HDL-C levels in PIO-treated group than those in control group, suggesting the beneficial effect of PIO on endothelial function in T2DM" - See pioglitazone at OffshoreRX.com.
• Pioglitazone Slows Progression of Carotid Atherosclerosis - Medscape, 6/9/09 - "A substudy of ACTOS Now, a diabetes prevention trial comparing pioglitazone (Actos, Takeda Pharmaceuticals) with placebo on risk and incidence of diabetes development, showed that active treatment with the thiazolidinedione slowed the rate of progression of carotid artery intima media thickness (CIMT) by 38% during a 3-year study period" - See Pioglitazone at OffshoreRX.com.
• Insulin Changes Occur Years Before Diabetes - WebMD, 6/9/09 - "A steady trend in fasting glucose as early as 13 years prior to the diagnosis of type 2 diabetes, with fasting glucose levels rising rapidly three years before diagnosis"
• Depression Raises Risk for Type 2 Diabetes - WebMD, 6/8/09 - "Depressed participants who were not being treated had significantly greater insulin resistance than study participants who were not depressed. But treatment for depression appeared to improve insulin sensitivity ... There are several theories about how depression may contribute to type 2 diabetes, but the most widely cited theory involves the stress hormone cortisol ... Cortisol is a key player in blood sugar metabolism and insulin sensitivity ... High cortisol levels are also associated with increased fat deposits around the abdomen, or belly fat, which is a risk factor for type 2 diabetes"
• Gestational Diabetes: Link to Sugary Drinks? - WebMD, 6/8/09 - "Compared to women who reported drinking less than one sugar-sweetened beverage per month, women who reported drinking five or more sugar-sweetened beverages per month were 22% more likely to report gestational diabetes. Colas were the only sugar-sweetened beverages linked to gestational diabetes"
• Protective Footwear For Diabetics At Main-street Prices - Science Daily, 5/26/09
• Too Much Or Too Little Sleep Increases Risk Of Diabetes - Science Daily, 4/21/09 - "The risk is 2½ times higher for people who sleep less than 7 hours or more than 8 hours a night"
• Long-Term Use of Antidepressants for Depressive Disorders and the Risk of Diabetes Mellitus - Am J Psychiatry. 2009 Apr 1 - "Compared with no use of antidepressants during the past 2 years, recent long-term use (>24 months) of antidepressants in moderate to high daily doses was associated with an increased risk of diabetes (incidence rate ratio=1.84, 95% CI=1.35-2.52). The magnitude of the risk was similar for long-term use of moderate to high daily doses of tricyclic antidepressants (incidence rate ratio=1.77, 95% CI=1.21-2.59) and selective serotonin reuptake inhibitors (incidence rate ratio=2.06, 95% CI=1.20-3.52)"
• Diabetes And Elevated Levels Of Cholesterol Linked To Faster Cognitive Decline In Alzheimer's Patients - Science Daily, 3/15/09
• Low Creatinine Levels Linked to Diabetes - Medscape, 3/13/09 - "The multiple-adjusted odds ratio for those who had serum creatinine between 0.40 and 0.60 mg/dL was 1.91 compared with those who had levels between 0.71 and 0.80 mg/dL"
• Shining Light On Diabetes-related Blindness - Science Daily, 3/11/09
• Diabetes Linked To Cognitive Deterioration - Science Daily, 3/5/09 - "people with diabetes were 1.5 more likely to experience cognitive decline, and 1.6 more likely to suffer from dementia than people without diabetes ... suggests that higher-than-average levels of blood glucose (blood sugar) may have a role in this relationship ... in people with type 2 diabetes, higher levels of haemoglobin A1C (a measure of average blood glucose) are significantly associated with poorer performance on three cognitive tasks which require memory, speed and ability to manage multiple tasks at the same time. A higher A1C level was also associated with a lower score on a test of global cognitive function ... lowering A1C levels could slow the accelerated rate of cognitive decline experienced by people with diabetes"
• Work the Night Shift? Beware Diabetes - WebMD, 3/2/09 - "The 8.6 million Americans who work the night shift are at increased risk of obesity, diabetes, and heart disease. Why? ... much of the body's biological clock -- its circadian rhythm -- keeps day-shift time even when a person goes on the night shift ... Cortisol -- the so-called stress hormone that affects blood pressure and blood sugar -- rose and dropped at the wrong time"
• Daily Diet Soda Consumption Linked to Metabolic Syndrome, Type 2 Diabetes - Medscape, 2/11/09 - "Compared with participants who did not drink diet soda, those who drank diet soda at least daily had a 36% greater relative risk for incident MetSyn (HR, 1.36; 95% confidence interval [CI], 1.11 - 1.66) and a 67% greater relative risk for incident type 2 diabetes"
• Doctors use diabetes test A1C as diagnostic tool- USA Today, 2/1/09 - "Within the next six months, a consensus by several leading diabetes organizations will lead to the publication of guidelines recommending the A1C test as a diagnostic tool for type 2 diabetes ... The benefit of the A1C test is that it can be taken at any time of day and is not thrown off by events of the day ... People who don't have diabetes typically have about a 6 or less reading"
• Getting Diabetes Before 65 More Than Doubles Risk For Alzheimer's Disease - WebMD, 1/28/09 - "getting diabetes before the age of 65 corresponds to a 125 percent increased risk for Alzheimer's disease"
• Diabetes Slows Brain Function - WebMD, 1/5/09 - "Mild diabetes slows mental function, even when kept under tight control ... Diabetes patients had normal reaction times and normal perceptual speed. But they were slower on tasks requiring rapid and precise processing of new verbal information. The defects involved speed and not verbal fluency"
• Most People Who Have Prediabetes Don’t Know It - WebMD, 11/6/08 - "Though only 4% of participants reported having prediabetes, researchers believe that 26% of adults have it, a figure based on laboratory test results in the 2003-2006 National Health and Nutrition Examination Survey"
• Diabetes Up 90% in U.S. - WebMD, 10/30/08 - "Scary Halloween news from the CDC: Type 2 diabetes is up 90% since 1997"
• Aspirin Does Not Prevent Heart Attacks In Patients With Diabetes, Study Suggests - Science Daily, 10/20/08
• Investigation on the relationship between diabetes mellitus type 2 and cognitive impairment - Diabetes Res Clin Pract. 2008 Oct 8 - "Subjects with diabetes (n=60) had lower MMSE score than those without diabetes (P<.01). Diabetes was also associated with increased odds of cognitive decline as determined by MMSE scores (odds ratio=1.9; CI=95%, 1.01-3.6). A significant correlation between duration of disease and cognitive dysfunction was observed, P=0.001 ... Diabetes mellitus is associated with lower levels of cognitive function"
• Type 2 Diabetes: Control Blood Sugar, Blood Pressure - WebMD, 9/10/08 - "If you've got type 2 diabetes, the sooner you get intense about reining in your blood sugar, the better. It also pays to buckle down on your blood pressure and stay that way"
• Low Cholesterol Associated With Cancer In Diabetics - Science Daily, 8/25/08
• Terminally Ill Rodents With Type 1 Diabetes Restored To Full Health With Single Dose Of Leptin - Science Daily, 8/25/08
• Diabetes Linked to Cognitive Problems - WebMD, 8/12/08
• Association of WBC count and glucose metabolism among Chinese population aged 40 years and over - Diabetes Res Clin Pract. 2008 Aug 6 - "We concluded that an increase in WBC count was associated with the deterioration of glucose tolerance"
• The angiotensin II receptor blocker telmisartan improves insulin resistance and has beneficial effects in hypertensive patients with type 2 diabetes and poor glycemic control - Diabetes Res Clin Pract. 2008 Aug 8 - "The telmisartan significantly improved HOMA-IR in hypertensive patients and also significantly decreased HbA1c in type 2 diabetic patients especially in the patients with poor glycemic control (HbA1c>==8.0%). These results indicate that telmisartan improves insulin resistance and gives beneficial effects in hypertensive patients with type 2 diabetes and a poor glycemic control" - Just another reason I feel that telmisartan should be the first line treatment for hypertension.  Click here for other reasons.  See telmisartan at OffshoreRX.com.
• Periodontal Disease May Independently Predict New-Onset Diabetes - Doctor's Guide, 8/7/08 - "Individuals with elevated levels of periodontal disease were nearly twice as likely to become diabetic in that 20-year timeframe"
• Telmisartan but not candesartan affects adiponectin expression in vivo and in vitro - Hypertens Res. 2008 Apr;31(4):601-6 - "the changes in serum adiponectin and plasma glucose over 3 months were significantly greater in the telmisartan group than in the candesartan group. In vitro, although the protein level of adiponectin was not significantly elevated, the mRNA expression of adiponectin was elevated 1.5-fold by telmisartan in 3T3-L1 adipocytes. Our findings suggest that telmisartan may have beneficial effects in type 2 diabetes beyond its antihypertensive effect" - I've been saying that telmisartan should be the first line treatment for hypertension for some time now if natural methods such as coenzyme Q10 don't work.
• Testosterone Gel Improves Insulin Sensitivity, Sexual Function in Hypogonadal Men With Diabetes and Metabolic Syndrome - Doctor's Guide, 6/20/08 - "Among patients with type 2 diabetes with or without metabolic syndrome, insulin resistance as measured by HOMA-IR improved from baseline in the testosterone-treated group compared with placebo at 6 months (testosterone: -0.62, placebo: +0.16; P = .049) and at 12 months (testosterone: -.58 ... Patients receiving testosterone also achieved more than a 5-point improvement over placebo-treated patients on the International Index of Erectile Function (IIEF) at 6 months (P < .05) and more than 6 points over placebo-treated patients at 12 months"
• Depression can trigger diabetes, study suggests - MSNBC, 6/17/08 - "Depressed people were 42 percent more likely to develop diabetes ... depression also pushes up the levels of stress hormones such as cortisol ... Elevated cortisol levels can impair insulin sensitivity in the body and encourage belly fat, a risk factor for diabetes"
• Pioglitazone Reduces Conversion From Impaired Glucose Tolerance to Diabetes - Medscape, 6/8/08 - "There was a weight gain of 3.9 kg in the pioglitazone group vs about 0.8 kg in the placebo group ... Over a mean follow-up of 2.6 years, pioglitazone markedly decreased, by 81%, the conversion rate of IGT to type 2 diabetes. IGT individuals who had the worst level of beta cell function and who were the most insulin resistant were the individuals who were most likely to develop type 2 diabetes, whether they were in the pioglitazone group...or the placebo group. Pioglitazone was quite safe and quite efficacious"
• Gum Disease May Make Diabetes Worse - WebMD, 6/6/08 - "The suggestion from the study is that treating gum disease could actually slow down the progression to diabetes in those at high risk of developing the disease"
• Diabetes Gel Regranex Linked to Cancer - WebMD, 6/6/08
• Long-term Pesticide Exposure May Increase Risk Of Diabetes - Science Daily, 6/4/08 - "Licensed pesticide applicators who used chlorinated pesticides on more than 100 days in their lifetime were at greater risk of diabetes, according to researchers from the National Institutes of Health (NIH). The associations between specific pesticides and incident diabetes ranged from a 20 percent to a 200 percent increase in risk"
• Fatty Liver Linked To Increased Risk Of Diabetic Kidney Disease - Science Daily, 5/29/08 - "For patients with type 2 diabetes, a condition called non-alcoholic fatty liver disease (NAFLD) may be an important risk factor for diabetes-related chronic kidney disease (CKD)" - See my liver disease page for way to reduce the risk of NAFLD.
• CDC: 52% With Diabetes Have Arthritis - WebMD, 5/8/08 - "Diabetes patients aged 18 to 44 have a 27.6% chance of having arthritis -- 2.5 times the 11% rate seen in the general population"
• Insulin Trouble Tied to Alzheimer's - WebMD, 4/9/08 - "the men took fasting glucose tests to show how well their body used insulin, a hormone that controls blood sugar ... Men who had a weaker insulin response to that test were 31% more likely to be diagnosed with Alzheimer's disease later in life" - See my Insulin and Aging page.
• Type 2 Diabetes Is Linked to Increased Risk for Parkinson's Disease - Science Daily, 3/28/08 - "individuals who developed type 2 diabetes had an 83% increased risk for PD compared with the general population ... insulin may play a role in regulation of brain dopanergic activity"
• Previously Unrecognized Testosterone Deficiency Common In Men With Type 1 Diabetes - Science Daily, 3/26/08 - "Testosterone deficiency, previously recognized as common in men with type 2 diabetes, is also common in men with type 1 diabetes"
• Antidepressants Linked To Type 2 Diabetes, Study Suggests - Science Daily, 3/25/08 - "the risk of diabetes almost doubled for the patients who were using two types of therapies at the same time, tricyclic antidepressants (TCAs) and selective serotonin reuptake inhibitors (SSRIs)"
• Diabetes Linked to Risk of Endometrial Cancer - Medscape, 3/13/08 - "An association was observed between type 2 diabetes and endometrial cancer (odds ratio = 1.7)"
• How Diabetes Drives Atherosclerosis - WebMD, 3/13/08 - "Abe's team showed that molecules called advanced glycation end products (AGEs), produced in greater levels by patients with diabetes, interfere with ERK5 cardioprotection. Glycation reactions cause the release of oxidizing side products like hydrogen peroxide (H202) that drive free radical production, inflammation and cell damage in many diseases" - I was always under the impression that it was advanced glycation end products in the first place.  I guess I was right before they discovered it.
• Weight Loss More Effective Than Intensive Insulin Therapy For Type 2 Diabetics - Science Daily, 3/11/08 - "Weight-loss and major lifestyle changes may be more effective than intensive insulin therapy for overweight patients with poorly controlled, insulin-resistant type 2 diabetes"
• Low Testosterone Levels are Common and Associated with Insulin Resistance in Men with Diabetes - J Clin Endocrinol Metab. 2008 Mar 4 - "Testosterone deficiency is common in men with diabetes, regardless of the type. Testosterone levels are partly influenced by insulin resistance, which may represent an important avenue for intervention"
• Diabetes May Be Disorder Of Upper Intestine: Surgery May Correct It - Science Daily, 3/5/08
• Study Questions Diabetes Threshold - WebMD, 2/29/08 - "More than 60% of the people with retinopathy didn't have fasting glucose levels in the range that is used to help diagnose type 2 diabetes"
• Adiponectin, Change in Adiponectin, and Progression to Diabetes in the Diabetes Prevention Program - Diabetes. 2008 Jan 11 - "Adiponectin is a powerful marker of diabetes risk in subjects at high risk of diabetes, even after adjustment for weight. An increase in adiponectin in lifestyle and placebo was associated with a reduction in diabetes risk. However, these changes in adiponectin were comparatively small and less strongly related to diabetes outcome than baseline adiponectin levels"
• Diabetes costs USA more than wars, disasters, study says - USATODAY.com, 1/23/08
• Androgen-Deprivation Therapy Linked to Diabetes - Medscape, 1/22/08 - "After controlling for other factors, the estimated relative risk of incident diabetes associated with ADT was a significant 1.36"
• Statins for All Adults with Diabetes? - WebMD, 1/10/08 - "One-third fewer people with type 1 or type 2 diabetes would suffer heart attacks or strokes if they took cholesterol-lowering statin drugs"
• Lack Of Deep Sleep May Increase Risk Of Type 2 Diabetes - Science Daily, 1/1/08 - "They found that when slow-wave sleep was suppressed for only three nights, young healthy subjects became about 25 percent less sensitive to insulin"
• Predictors of cognitive impairment and dementia in older people with diabetes - Diabetologia. 2007 Dec 5 - "Peripheral arterial disease is a strong independent risk factor for dementia in diabetes"
• Pioglitazone Lowers Cardiovascular Risk in Diabetic Patients with Kidney Disease - Doctor's Guide, 12/12/07
• Diabetes May Increase Woman's Risk of Colorectal Cancer - oncologystat.com, 12/7/07 - "There was about a 50% increased risk of colorectal cancer in women with diabetes ... The researchers hypothesized that the elevated levels of insulin typically seen in people with type 2 diabetes may play a central role. Insulin stimulates the growth of normal colonic and carcinoma cells"
• Testosterone, diabetes mellitus, and the metabolic syndrome - Curr Urol Rep. 2007 Nov;8(6):467-71 - "One third of men with type 2 diabetes mellitus are now recognized as testosterone deficient. Emerging evidence suggests that testosterone therapy may be able to reverse some aspects of metabolic syndrome"
• Mental Health Treatment Extends Lives Of Older Patients With Diabetes And Depression - Science Daily, 12/5/07 - "Researchers at the University of Pennsylvania School of Medicine report that older adults with diabetes and depression are half as likely to die over a 5-year period when they receive depression care management than depressed patients with diabetes who do not receive depression care management"
• Insufficient Sleep Raises Risk Of Diabetes, Study Suggests - Science Daily, 12/1/07 - "subjects who reported sleeping five or fewer hours and subjects who reported sleeping nine or more hours were significantly more likely to have incident diabetes over the follow-up period than were subjects who reported sleeping seven hours"
• Prevention of Type 2 diabetes: fact or fiction? - Expert Opin Pharmacother. 2007 Dec;8(18):3147-58 - "Both studies have shown that intensive lifestyle intervention could reduce the progression of IGT to diabetes by 58%. Furthermore, four currently-available drugs have been established as being effective in preventing diabetes in subjects with prediabetes. The Diabetes Prevention Program revealed that metformin 850 mg b.i.d. reduced the risk of diabetes by 31%. The STOP-NIDDM (Study To Prevent Non-Insulin-Dependent Diabetes Mellitus) trial (n = 1429) showed that acarbose 100 mg t.i.d. with meals decreased the incidence of diabetes by 36% when the diagnosis was based on 2 oral glucose tolerance tests. The XENDOS (Xenical in the Prevention of Diabetes in Obese Subjects) study examined the use of orlistat, an antiobesity drug, as an adjunct to an intensive lifestyle modification program in obese non-diabetic subjects. Orlistat treatment resulted in a 37% decline in the development of diabetes. More recently, the DREAM (Diabetes Reduction Assessment with Ramipril and Rosiglitazone Medication) study (n = 5269) demonstrated that rosiglitazone at 8 mg once/day in subjects with prediabetes (IGT and/or impaired fasting glucose) was effective in reducing the risk of diabetes by 60%. It can be concluded that Type 2 diabetes can be prevented or delayed through lifestyle modifications and/or pharmacologic interventions. This is a fact"
• Low Serum Testosterone Concentration in Middle-aged Men with Type 2 Diabetes - Endocr J. 2007 Nov 12 - "serum free testosterone concentration is certainly lower in a relatively large number of Japanese patients with type 2 diabetes compared with healthy men with each decade of life between 40 and 69 years old"
• Candesartan Improves Outcomes in Diabetes, Kidney Patients - Doctor's Guide, 11/8/07 - "new onset diabetes occurred in just 1.1% of the 1,024 patents on candesartan compared with 2.9% of the patients treated with other blood pressure lowering medications that did not include angiotensin receptor blockers ... "We observed that treatment with candesartan reduced that risk by 63% (P =.027)," he said during a press briefing. He also noted that patients on candesartan had fewer adverse events than the 1,025 patients who received standard therapy" - I would have liked to see telmisartan (also an ARB) in this study.
• UCSD Researchers Discover Inflammation, Not Obesity, Cause of Insulin Resistance - Doctor's Guide, 11/6/07 - "The research also proved that obesity without inflammation does not result in insulin resistance ... when an animal or a human being becomes obese, they develop steatosis, or increased fat in the liver. The steatosis leads to liver inflammation and hepatic insulin resistance"
• 13% of Americans Have Kidney Disease - WebMD, 11/6/07 - "Thirteen percent of Americans now have chronic kidney disease, up 3% over the last decade, mostly due to higher rates of diabetes and high blood pressure ... A recent CDC report on the same NHANES data suggested that 17% of Americans have chronic kidney disease. Coresh and colleagues came up with a lower number because the CDC analysis included people with earlier signs of kidney disease, while the Coresh team counted only those with persistent kidney disease"
• Type 2 Diabetes: Inflammation, Not Obesity, Cause Of Insulin Resistance - Science Daily, 11/6/07 - "If we can block or disarm this macrophage inflammatory pathway in humans, we could interrupt the cascade that leads to insulin resistance and diabetes"
• Preventing Or Reducing Enlarged Heart May Decrease Risk For Diabetes - Science Daily, 10/31/07
• Women With High Or Increasing Blood Pressure Are Up To Three Times More Likely To Develop Diabetes - Science Daily, 10/9/07 - "women who have high blood pressure levels are three times more likely to develop diabetes than women with low blood pressure levels ... The authors suggest a possible mechanism for the relation between BP and diabetes may be endothelial dysfunction -- a dysfunction of the normal biochemical processes carried out by the layer of cells that line the inner surfaces of blood vessels. "It may be a precursor of both hypertension and diabetes," ... the progression of endothelial dysfunction may cause worsening of both BP and blood glucose. This is in line with the fact that both BP and blood glucose occur together as part of the metabolic syndrome"
• Homocysteine and diabetic retinopathy - Diabetes Care. 2007 Sep 26 - "Plasma total homocysteine concentration may be a useful biomarker and/or a novel risk factor for increased risk of diabetic retinopathy in people with type 2 diabetes"
• Reducing Inflammation Plays Key Role In Type 1 Diabetes Therapy - Science Daily, 7/31/07
• Most Diabetes Drugs Provide Similar Glucose Control - Doctor's Guide, 7/17/07
• Diabetes Linked to Alzheimer's Disease - WebMD, 6/26/07 - "the relatively high levels of insulin in people with type 2 diabetes may spur development of the amyloid protein that is present in the brains of Alzheimer's patients. High insulin levels may also trigger a cascade of potentially harmful chemical signals in the brain"
• Omega-3s May Help Prevent Blindness - WebMD, 6/25/07
• Can Blindness Be Prevented Through Diet? - Science Daily, 6/24/07 - "Increasing intake of the omega-3 fatty acids DHA and EPA, found in popular fish-oil supplements, may protect against blindness resulting from abnormal blood vessel growth in the eye ... Mice on the omega-3 diet, rich in DHA (docosahexaenoic acid) and its precursor EPA (eicosapentaenoic acid), had less initial vessel loss in the retina than the omega-6-fed mice: the area with vessel loss was 40 to 50 percent smaller" - See Mega Twin EPA at iHerb or Jarrow Max DHA at iHerb.
• (How) Can We Prevent Type 2 Diabetes? - Medscape, 6/18/07 - "Thiazolidinediones have produced relative risk reductions in the range of 55–62%"
• Screening of Cushing's syndrome in adult patients with newly diagnosed diabetes mellitus - Clin Endocrinol (Oxf). 2007 Jun 4 - "unknown CS is not rare among patients with diabetes mellitus ... early diagnosis and treatment of CS may provide the opportunity to improve the prognosis of diabetes"
• Thiazide and Beta-Blocker Use Linked With Increased Risk for Incident Diabetes - Medscape, 5/8/07 - "the relative risk of incident diabetes for those taking a thiazide diuretic compared with those not taking a thiazide was 1.20 (95% confidence interval [CI], 1.08 - 1.33) in older women; 1.45 (95% CI, 1.17 - 1.79) in younger women; and 1.36 (95% CI, 1.17 - 1.58) in men ... the risk for incident diabetes was also increased in patients taking beta-blockers relative to those who were not: 1.32 (95% CI, 1.20 - 1.46) in older women and 1.20 (95% CI, 1.05 -1.38) in men. In younger women, a category of "other antihypertensives" was used that included beta-blockers, and their use was associated with an increased risk for 1.46"
• Hyperglycemia Linked to Cancer Risk - Physician's Weekly, 5/7/07 - "Risk of cancer of the pancreas, endometrium, urinary tract, and of malignant melanoma was statistically significantly associated with high fasting glucose with [relative risk ratios] of 2.49, 1.86, 1.69, and 2.16, respectively"
• Tight Diabetes Control Does not Impact Cognitive Ability in Type 1 Diabetes - Doctor's Guide, 6/5/07
• Why Wounds Are Slow To Heal In Diabetics - Science Daily, 5/4/07
• Numbness could signal diabetes complication - USA Today, 4/29/07
• Drugs to Prevent Diabetes Questioned - WebMD, 4/26/07 - "the long-term benefits of such treatments are not known ... Avandia was found to lower type 2 diabetes risk by 62% among people at high risk for developing the disease in a large, international trial reported last fall"
• Stem Cells May Stop Type 1 Diabetes - WebMD, 4/10/07
• Effect of inhibition of the Renin-Angiotensin system on development of type 2 diabetes mellitus (meta-analysis of randomized trials) - Am J Cardiol. 2007 Apr 1;99(7):1006-12. Epub 2007 Feb 16 - "In ACE inhibitor trials, the odds of developing DM were reduced by 28% (OR 0.72, 95% CI 0.63 to 0.84, p <0.001), and in the 5 ARB studies, there was a 27% reduction (OR 0.73, 95% CI 0.64 to 0.84, p <0.001) in the odds. In conclusion, evidence accumulated to date indicates that inhibition of the renin-angiotensin system may contribute to the prevention of DM"
• Erectile Dysfunction In Diabetes Is Due To Selective Defect In The Brain - Science Daily, 3/15/07
• Telmisartan and irbesartan therapy in type 2 diabetic patients treated with rosiglitazone: effects on insulin-resistance, leptin and tumor necrosis factor-alpha - Hypertens Res. 2006 Nov;29(11):849-56 - "The decrease in HbA1c and FPG at 12 months was statistically significant only in the telmisartan group"
• Erectile Dysfunction Drugs Prove Effective, Safe For Men With Diabetes, Review Finds - Science Daily, 1/24/07
• Viagra-like Drugs Can Treat Erectile Dysfunction In Men With Diabetes - Science Daily, 1/24/07
• Which Drug for Initial Treatment of Type 2 Diabetes? - Medscape, 1/17/07 - "rosiglitazone was moderately more effective than the other two drugs in controlling fasting glucose levels during the first several years after diagnosis of type 2 diabetes"
• The effect of telmisartan on glucose and lipid metabolism in nondiabetic, insulin-resistant subjects - Metabolism. 2006 Sep;55(9):1149-54 - "in insulin-resistant persons 12 weeks of telmisartan result in a significant improvement in glucose metabolism with a predominant improvement in beta-cell function"
• ACE Inhibitors Reduce Kidney Disease Risk in Diabetics with High Blood Pressure - Doctor's Guide, 11/2/06 - "Taking an ACE inhibitor, alone or as part of the combination treatment, provided further protection against diabetic kidney disease"
• Periodontal Therapy Helps Patients With Type 2 Diabetes - Doctor's Guide, 10/31/06
• Diabetes in Middle Age = More Problems - WebMD, 10/27/06
• High Glucose Before Surgery Raises Risk Of Dangerous Complications - Science Daily, 10/16/06
• Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial - Lancet. 2006 Sep 23;368(9541):1096-105 - "306 (11.6%) individuals given rosiglitazone and 686 (26.0%) given placebo developed the composite primary outcome (hazard ratio 0.40, 95% CI 0.35-0.46; p<0.0001); 1330 (50.5%) individuals in the rosiglitazone group and 798 (30.3%) in the placebo group became normoglycaemic ... Rosiglitazone at 8 mg daily for 3 years substantially reduces incident type 2 diabetes and increases the likelihood of regression to normoglycaemia in adults with impaired fasting glucose or impaired glucose tolerance, or both"
• Diabetes pill works — but at what cost? - MSNBC, 9/26/06 - "Half got a drug called Avandia, already on the market to treat diabetes. The other half took a placebo, a dummy pill. After three years, 62 percent fewer people on the medication developed diabetes ... modest weight loss (5 to 7 percent of body weight) and light exercise (a 30 minute walk each day) brought a 58 percent reduction in progression to diabetes in the same at-risk people ... A month’s supply of Avandia in the dose needed for reducing diabetes risk costs about $120"  - See rosiglitazone at SuperSaverMeds.com or XlPharmacy.
• Diabetes, Not Obesity, Increases Risk Of Developing Critical Illness And Early Death - Science Daily, 9/25/06 - "in the absence of diabetes, obese individuals do not have an increased risk of suffering from acute organ failure, and of dying from acute organ failure, than non-obese individuals. By contrast, patients with diabetes are three times more likely to become critically ill with acute organ failure and they are three times more likely to die from acute organ failure, or from any cause, than patients who do not have diabetes, regardless of their BMI"
• Diabetes May Raise Cancer Risk - WebMD, 9/25/06 - "Total cancer risk was found to be 27% higher for men with diabetes than for men without the disease ... It has been suggested that excess insulin in people with type 2 diabetes may promote the growth of pancreatic and liver cancers ... Preventing diabetes can certainly lower your cardiovascular risk, and it appears that the same is true for certain cancers"
• Study Adds to Links Between Sleep Loss and Diabetes - Doctor's Guide, 9/19/06 - "short or poor sleep is associated with decreased blood-sugar control in patients who already have diabetes"
• Got Type 2 Diabetes? Get Better Sleep - WebMD, 9/18/06
• Drug 'Avandia' May Prevent Diabetes - WebMD, 9/15/06 - "People at high risk for diabetes who took the drug Avandia reduced their risk of developing the disease by 60% in the three-year trial" -  See rosiglitazone at OffshoreRx.com or SuperSaverMeds.com.
• Researchers Find Added Benefit of Statins in Those at High Risk for Heart Disease, Diabetes - Doctor's Guide, 9/13/06 - "found marked reductions in two pivotal biomarkers of inflammation: C-reactive protein (CRP) and interleukin-6. While these markers are typically elevated in insulin resistance, a condition that precedes the development of diabetes, statin therapy reduced these levels by 36% and 44%, respectively"
• Diabetes Prevention: 6 New Guidelines - WebMD, 8/25/06
• Eli Lilly and Company Receives Approvable Letter From FDA for Arxxant(TM) (Ruboxistaurin Mesylate) - Doctor's Guide, 8/18/06
• Uncontrolled Diabetes Linked to Later Development of Dementia - Doctor's Guide, 7/21/06
• Influences of statins on glucose tolerance in patients with type 2 diabetes mellitus - J Atheroscler Thromb. 2006 Apr;13(2):95-100 - "atorvastatin-treated group (Group A ... arbitrary blood glucose levels increased from 147 +/- 50 (mean +/- SD) mg/dL to 177 +/- 70 mg/dL in Group A"
• Better Blood Sugar = Less Alzheimer's - WebMD, 7/17/06 - "there were almost 20% fewer new cases of Alzheimer's among people taking thiazolidinediones compared with people who took insulin. Similar results were found in a separate comparison between thiazolidinediones users and people starting Glucophage, another drug used to treat diabetes"
• Type 2 Diabetes Increases The Risk Of Glaucoma In Women - Science Daily, 7/12/06
• ACE Inhibitors and Angiotensin Receptor Antagonists and the Incidence of New-Onset Diabetes Mellitus : An Emerging Theme - Drugs. 2006;66(9):1169-1177 - "These trials have demonstrated an approximately 15-30% reduction in the new onset of diabetes in those receiving ACE inhibitors and ARBs when compared with placebo or other active therapy"
• Important Drugs Underutilized in Older Diabetics - Physician's Weekly, 7/3/06 - "The authors recommended ACE/ARB therapy for all older patients with diabetes to improve quality of national diabetes care"
• Diabetes Confers Earlier Heart Risk - WebMD, 6/29/06 - "in general, people with diabetes have a risk for heart disease (such as heart attack), stroke, and death from any cause similar to someone more than a decade older but without the disease"
• Do Low-Carb Diets Help Diabetes? - WebMD, 6/16/06 - "16 obese patients with type 2 diabetes followed a calorie- and carbohydrate-restricted diet for 22 months. Most showed continuing improvements in blood sugar that were independent of weight loss; the average daily dosage of insulin among the 11 insulin-dependent patients was cut in half"
• High Blood Sugar Linked to More ICU Deaths - Intelihealth, 6/13/06 - "Even modest hyperglycemia - starting at just one point above normal glucose levels -- was associated with mortality"
• Study: A daily pill could narrow the scope of diabetes - USA Today, 6/11/06 - "If everyone who had the most common form of diabetes were given a daily "polypill" that combined low-dose aspirin with commonly used drugs to lower cholesterol, blood pressure and blood sugar, it would prevent 7.2 million deaths and disabilities that result from the disease"
• Obesity and Diabetes Increase Risk for Benign Prostatic Hyperplasia - Doctor's Guide, 5/29/06 - "men with elevated fasting plasma glucose levels (>110 mg/dL) were 3 times more likely to have prostate enlargement"
• 1 in 3 Americans at Risk for Diabetes - WebMD, 5/26/06
• One-Third of Adults With Diabetes Still Don't Know They Have It - Doctor's Guide, 5/26/06 - "About 2.8% of U.S. adult -- one-third of those with diabetes -- still don't know they have it ... about 26% of adults age 20 and older continued to have impaired fasting glucose (IFG), a form of pre-diabetes ... nearly 40% of people age 65 and older had IFG, which becomes more common with age ... A major study of people with IGT has shown that lifestyle changes leading to a 5 to 7% weight loss lowered diabetes onset by 58%"
• Women With Type 2 Diabetes at Increased Risk of Colorectal Adenomas - Doctor's Guide, 5/23/06 - "type 2 diabetics had up to a 2- to 3-fold increased risk of having any adenoma or advanced adenomas, which are precancerous polyps"
• Lower Testosterone Levels Among Some Diabetic Patients May Lead to Increased Risk of Cardiovascular Disease - Doctor's Guide, 4/27/06 - "Men with type 2 diabetes should have their testosterone monitored, because one third of them may have low testosterone that could be related to a significantly higher risk of cardiovascular disease"
• Good Blood Sugar Control Before Surgery Associated With Fewer Infections Afterward Among Patients With Diabetes - Doctor's Guide, 4/17/06
• Two Tests Better Than One for Diabetes Control, Johns Hopkins Expert Tells Doctors - Doctor's Guide, 4/13/06
• Periodontal Therapy May Help Diabetic Patients Improve Sugar Control - Doctor's Guide, 4/12/06 - "periodontal therapy may reduce a diabetic patient's HbA1c count by as much as 20% at three and six months following treatment"
• Sleep Length May Sway Diabetes Risk - WebMD, 3/15/06
• Diabetics Who Control Blood Sugar Today Are More Likely to Have Healthy Feet and Nerves Tomorrow - Doctor's Guide, 3/10/06
• Eating Potatoes May Increase Risk for Type 2 Diabetes - Medscape, 3/2/06 - "After adjustment for age and dietary and nondietary factors, potato and french fry consumption were both positively associated with risk for type 2 diabetes. Comparing the highest and the lowest quintile of potato intake, the multivariate relative risk (RR) for diabetes was 1.14 (95% confidence interval [CI], 1.02 - 1.26; P for trend, .009). Comparing the highest and the lowest quintile of french fry intake, the multivariate RR was 1.21"
• Byetta: A Ray of Hope for Diabetics - New York Times, 3/2/06
• Laser Prevents Diabetes Amputation - WebMD, 2/15/06
• Diabetes Can Lead to Gum Disease in Childhood; Onset Is Younger Than Previously Recognized - Doctor's Guide, 2/8/06
• Study Finds More Fractures, Less Bone Density In Premenopausal Women With Diabetes - Doctor's Guide, 1/27/06
• Type 1 Diabetes Tied to Thinner Bones - WebMD, 1/27/06
• Brain Plays Key Role In Diabetes Therapy - Science Daily, 1/11/06
• Tight Glucose Control Cuts Heart Disease By Half In Type 1 Diabetes - Doctor's Guide, 12/22/05
• Survey Finds Nearly Half of People With Diabetes Are Not Using Aspirin to Reduce Risk of Heart Attack and Recurrent Stroke - Doctor's Guide, 11/22/05
• FDA Approves New Indication for Invanz (Ertapenem) for Treatment of Moderate to Severe Complicated Foot Infection in Diabetic Patients without Osteomyelitis - Doctor's Guide, 11/14/05
• Lifestyle Changes Reverse Type 2 Diabetes in Study Participants - Doctor's Guide, 11/3/05 - "Those who have or are at-risk of developing type 2 diabetes may be able to reverse the illness by improving their diet and engaging in regular exercise"
• Diabetics Face Increased Risk of Colorectal Cancer - Doctor's Guide, 11/2/05 - "hyperinsulinemia and hyperglycemia promote the growth of colorectal cancer"
• Diabetes and Depression Can Be a Fatal Mix - Doctor's Guide, 10/28/05
• Achilles Tendon Surgery Helps Prevent Diabetic Foot Ulcers - Doctor's Guide, 10/28/05
• Diabetes And Depression Can Be A Fatal Mix - Science Daily, 10/25/05
• Combination therapy using metformin or thiazolidinediones and insulin in the treatment of diabetes mellitus - Diabetes Obes Metab. 2005 Nov;7(6):633-41 - "The biguanide, metformin, sensitizes the liver to the effect of insulin, suppressing hepatic glucose output. Thiazolidinediones such as rosiglitazone and pioglitazone enhance insulin-mediated glucose disposal, leading to reduced plasma insulin concentrations. These classes of drugs may also have varying beneficial effects on features of insulin resistance such as lipid levels, blood pressure and body weight. Metformin in combination with insulin has been shown to significantly improve blood glucose levels while lowering total daily insulin dose and body weight"
• More Aggressive Diabetes Treatment Needed - Doctor's Guide, 10/11/05 - "Primary care physicians treat about 90% of all patients with diabetes in the United States, but receive relatively little training in medical school on the subject ... Target fasting blood glucose levels should be 80 to 100 mg/dL and dinner glucose levels should be <140 mg/dL"
• High Blood Glucose Levels in Early Pregnancy May Deprive Embryo of Oxygen and Lead to Birth Defects, Joslin Diabetes Center Study Shows - Doctor's Guide, 10/4/05
• Nerve Changes from Diabetes Begin Earlier Than Previously Known - Doctor's Guide, 9/30/05
• Cause Of Diabetes-related Erectile Dysfunction Is Clarified By Johns Hopkins Researchers - Science Daily, 8/11/05 - "one particular simple sugar, present in increased levels in diabetics, interferes with the chain of events needed to achieve and maintain erection and can lead to permanent penile impairment over time"
• Strategies to Prevent Type 2 Diabetes - Medscape, 8/8/05 - "Low glycemic load, high fiber diet which contains adequate amounts of mono-unsaturated and omega-3 fats and lean protein can improve satiety and dietary thermo-genesis (basal metabolic rate) and decrease insulin resistance ... Nutrients that have also been associated with worsening insulin sensitivity include trans-fats and saturated fats ... Exercise improves insulin sensitivity and lowers glucose levels both acutely and for up to 48 h after physical activity ... metformin reduced the risk of diabetes by 31% ... Valsartan reduced the incidence of new-onset diabetes by 23% ... Traditional beta-blockers worsen insulin sensitivity and increase the risk of developing new diabetes"
• Type 2 diabetes mellitus and the risk of colorectal cancer - Clin Gastroenterol Hepatol. 2005 Jun;3(6):587-94 - "Type 2 diabetes mellitus is associated with an increased risk of colorectal cancer"
• Tight Glucose Control Lowers Cardiovascular Disease by About 50 Percent in Diabetics - Doctor's Guide, 6/17/05
• Avoiding Amputation: Early Infection Intervention Can Save Feet and Legs - Doctor's Guide, 6/16/05
• Cut the Pain in Diabetes Blood Sugar Test - WebMD, 6/13/05
• Diabetics control glucose, lower cardiac risk - USATODAY.com, 6/12/05 - "Early, intensive treatment to keep blood sugar levels close to normal in people with diabetes can cut their risk of cardiovascular disease by about 50% and the risk of heart attack and stroke by 57%, much better results than those achieved by any cholesterol or blood pressure drug"
• Byetta (Exenatide), Newly Approved First-in-Class Treatment for Type 2 Diabetes, Now Available in US - Doctor's Guide, 6/9/05 - "Byetta is the first in a new class of diabetes treatment called incretin mimetics. By mimicking the mechanisms of a naturally occurring human hormone, Byetta is a diabetes self regulating drug that stays in the blood system, working actively only when blood sugar levels are too high"
• NC Woman Is Now Insulin-free After Series Of Three Islet Cell Transplants - Science Daily, 6/9/05
• People With Diabetes More Sensitive to Cardiovascular Effects From Air Pollution - Doctor's Guide, 5/31/05
• Men With Diabetes, Hypertension, or Hyperlipidemia More Likely to Be Hypogonadal - Doctor's Guide, 5/25/05 - "In men with a history of diabetes, 50% were hypogonadal"
• AACE Announces New A1c Standard of 6.5% or Lower - Medscape, 5/24/05
• Insulin Resistance Correlates With Rises in C-Reactive Protein - Doctor's Guide, 5/23/05 - "As C-reactive protein rises, so does insulin resistance ... Increased C-reactive protein levels may also predispose to accelerated or premature atherosclerotic disease ... Maybe someday we'll have therapy to lower C-reactive protein levels"
• Valsartan Reduces Chance of Diabetes in High-Risk Hypertensive Patients - Doctor's Guide, 5/19/05 - "patients taking valsartan had a 23% lower risk of developing diabetes during the four or more years of the study. The two drugs had previously been shown to be roughly equivalent in reducing the risk of heart attack and stroke" - See valsartan at OffshoreRX.com.
• U.S. Diabetes Control Dangerously Poor - WebMD, 5/18/05 - "Two-thirds of patients with type 2 diabetes do not adequately control their blood sugar"
• Metabolic Effect of Telmisartan [Micardis] and Losartan [Cozaar] in Hypertensive Patients with Metabolic Syndrome - Cardiovasc Diabetol. 2005 May 15;4(1):6 - "Telmisartan, but not losartan, significantly (p < 0.05) reduced free plasma glucose, free plasma insulin, homeostasis model assessment of insulin resistance and HbAic. Following treatment, plasma glucose and insulin were reduced during the oral glucose tolerance test by telmisartan, but not by losartan. Telmisartan also significantly reduced 24-hour mean systolic blood pressure (p < 0.05) and diastolic blood pressure (p < 0.05) compared with losartan"
• Type 2 Diabetes May Begin With Grandma's Diet - Science Daily, 5/12/05 - "the insulin resistance typical of type 2 diabetes can be "programmed" across two generations by poor nutrition during a grandmother's pregnancy and lactation"
• Study Suggests Antibiotic May Limit or Prevent Vision Problems Caused by Diabetes - Doctor's Guide, 5/10/05
• Combination Therapy The Next Wave For Diabetic Dyslipidemia - Doctor's Guide, 5/2/05 - "Ezetimibe and prolonged-release nicotinic acid show the most promise so far when combined with a statin ... extended-release form of nicotinic acid (Niaspan) ... taking 1000 mg or 1500 mg per day experienced increases in serum high-density lipoprotein (HDL) cholesterol levels of 19% and 24%"
• Statins Urged for Diabetic Patients - Doctor's Guide, 5/2/05 - "diabetics who are older than 40 years of age whose total cholesterol exceeds 3.5 mmol/L (135 mg/dL) should be placed on statin therapy to achieve a 30% to 40% reduction in LDL level, regardless of their baseline LDL level and even if they do not have overt cardiovascular disease"
• FDA Approves New Diabetes Treatment - CBS 2 Chicago, 4/29/05
• FDA Approves of Byetta (Exenatide) Injection, Treatment for Type 2 Diabetes - Doctor's Guide, 4/29/05
• Long or Short Sleep Time May Be Associated With Diabetes - Medscape, 4/26/05 - "Sleep duration of six hours or less or nine hours or more is associated with increased prevalence of diabetes mellitus (DM) and impaired glucose tolerance (IGT)"
• Strategies for Insulin Therapy in Type 2 Diabetes - Medscape, 4/18/05
• ACE Inhibitors or ARBs for Prevention of Type 2 Diabetes: A Meta-analysis of Randomized Clinical Trials - Medscape, 4/18/05 - "the use of valsartan reduced the incidence of new-onset type 2 diabetes by 23%"
• Retin A May Help Avoid Diabetes Ulcers - WebMD, 3/25/05
• Waistline better indicator of diabetes than BMI - MSNBC, 3/21/05 - "Compared to those in the group with the smallest waists, 29-34 inches, men with larger waist sizes were at least twice as likely to have diabetes. Those with the largest waist size — 40 inches and above — were up to 12 times more likely to have Type 2 diabetes"
• Moderate Drinking May Prevent Type 2 Diabetes - WebMD, 3/21/05
• Waist Size Predicts Diabetes Risk - WebMD, 3/10/05 - "a man's waist size is a better indicator of type 2 diabetes risk than other currently used measures, such as waist-to-hip ratio and body mass index (BMI, a measure of weight in relation to height)."
• Forearm Blood Sugar Tests Not Always Accurate - WebMD, 3/8/05
• Elevated Glucose Levels And Diabetes Are Associated With Increased Risk For Cancer - Science Daily, 1/19/05 - "the group with the highest fasting serum glucose (140 mg/dL or greater [7.8 mmol/L or greater]) had a higher death rates from all cancers combined (29 percent higher for men; 23 percent higher for women) compared with the group with the lowest level (less than 90 mg/dL [less than 5.0 mmol/L])"
• High Blood Sugar Raises Cancer Risk - WebMD, 1/11/05 - "the men in the study with the highest fasting blood sugar levels (those greater than 140 mg/dl) were 29% more likely to die of cancer than men with the lowest levels (those less than 90 mg/dl). The difference among women with the highest and lowest blood sugar levels was 23%"
• Study links diabetes to cancer risk - MSNBC, 1/11/05 - "diabetes can raise the risk of developing and dying from several types of cancer, including digestive-tract tumors"
• Gum Disease Ups Death Risk in Diabetes Patients - WebMD, 1/7/05
• High Blood Sugar Hurts Thinking - WebMD, 12/22/04 - "More than half of the group (55%) didn't think as clearly as normal when their blood sugar was too high. They responded more slowly or made more verbal and subtraction errors when their blood sugar levels were high"
• Hyperglycemia Slows Mental Functions in People with Diabetes - Doctor's Guide, 12/22/04
• Testosterone Deficiency Found In One-Third Of Diabetic Men - Science Daily, 11/29/04 - "The surprisingly high prevalence of low testosterone levels was associated with lower levels of pituitary hormones called gonadotrophins ... The high prevalence of low testosterone in diabetic men is concerning, said Dhindsa, because in addition to lowered libido and erectile dysfunction, the condition is associated with loss of muscle tone, increase in abdominal fat, loss of bone density, and can affect mood and cognition"
• Testosterone Deficiency Found in One-Third of Diabetic Men - Doctor's Guide, 11/29/04
• People With Diabetes at Risk for Depression - WebMD, 11/24/04
• Ertapenem Produces Results Comparable to Piperacillin/Tazobactam in Diabetic Foot Infections - Medscape, 11/1/04
• Weight Loss Surgery Can Cure Diabetes - WebMD, 10/12/04
• Death Risk Rises With Blood Sugar - WebMD, 9/20/04 - "As your blood sugar level goes up, so does your risk of death and heart disease - even if you don't have diabetes ... we should be concerned about blood glucose elevations even in people who do not have diabetes"
• Cardiovascular therapies and risk for development of diabetes - J Am Coll Cardiol. 2004 Aug 4;44(3):509-12 - "Treatment with angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, and calcium antagonists yielded a lower incidence of diabetes development than beta-blockers and diuretics"
• Do Bacon and Hot Dogs Trigger Diabetes? - WebMD, 9/8/04 - "Compared with women who eat less red meat, women who eat red meat frequently have almost a third higher risk of developing type 2 diabetes. Frequently eating bacon, hot dogs, and processed (deli-style) meats was associated with a 43% higher risk of type 2 diabetes"
• Higher Consumption of Sugar-Sweetened Beverages Associated with Increased Risk for Type 2 Diabetes - Doctor's Guide, 8/25/04
• Diabetes Speeds Memory Decline in Older Women - WebMD, 8/24/04
• Soft Drinks: Too Much of a Bad Thing? - WebMD, 8/24/04 - [Abstract] "women who increased their intake of sugar-sweetened soft drinks or fruit punch from one can per week to one per day gained more weight and doubled their risk of type 2 diabetes compared with women who did not increase their intake"
• Statin use in Type 2 diabetes mellitus is associated with a delay in starting insulin - Diabet Med. 2004 Sep;21(9):962-7 - "The use of statins is associated with a delay in starting insulin treatment in patients with Type 2 diabetes initially treated with oral antidiabetic agents"
• Type 2 Diabetes: Silent Heart Problems - WebMD, 8/6/04
• Diabetic Foot Ulcers Tied to Activity Levels - WebMD, 8/5/04
• Caffeine May Hamper Blood Sugar Control - WebMD, 7/26/04
• Enalapril/Losartan Combination Results in Greater Reduction of Proteinuria in Patients With Type 2 Diabetes - Doctor's Guide, 7/9/04
• Cognitive Decline in Verbal Fluency Significantly Greater Over Time in Older Women with Diabetes Compared with Non-Diabetics - Doctor's Guide, 6/30/04
• New Antibiotics Advance The Treatment Of Diabetic Foot Infections - Doctor's Guide, 6/30/04
• Triple Therapy Fights Type 2 Diabetes Without Weight Gain - Doctor's Guide, 6/28/04
• Erectile Dysfunction in Diabetic Men May Predict Silent Heart Disease - Doctor's Guide, 6/22/04
• ED May Predict Heart Disease in Diabetic Men - WebMD, 6/21/04
• Dyslipidemia in Diabetics Needs More Aggressive Treatment - Doctor's Guide, 6/7/04
• Sugary Sodas Add Pounds, Raise Diabetes Risk - WebMD, 6/7/04 - "women who went from drinking less than one non-diet soda a day to one or more sodas a day gained more weight and were nearly twice as likely to develop type 2 diabetes over a four-year period than women who drank less than one soft drink a day"
• Glycemic Control Significantly Improves Working Memory in Type 2 Diabetics - Doctor's Guide, 6/7/04
• Heart Drug Benefits Type 2 Diabetes - WebMD, 5/26/04
• Oxygen Therapy May Improve Vision Worsened By Diabetes - Science Daily, 5/19/04
• New Guidelines Call for More Extensive Use of Statins for Patients With Diabetes - Doctor's Guide, 4/23/04
• FDA Approves Rapid-Acting Insulin Analogue Apidra - Doctor's Guide, 4/20/04
• Nearly All With Type 2 Diabetes Need Statins - WebMD, 4/19/04 - "no matter how low the cholesterol count, nearly all people with diabetes should take these cholesterol-lowering drugs"
• Intensified Treatment of Diabetic Nephropathy Slows Renal Disease Progression - Doctor's Guide, 4/1/04
• C-Reactive Protein as Independent Predictor of Type 2 Diabetes in Women - Doctor's Guide, 3/8/04 - "Elevated plasma C-reactive protein (CRP), an inflammatory biomarker, is an independent risk factor for type 2 diabetes in females ... C-reactive protein is a sensitive and stable marker for systemic inflammation, and may be a potential target for intervention in healthy subjects" - See my CRP page for ways to reduce it.
• Diabetes Linked With Alzheimer's Disease - WebMD, 2/19/04
• Diabetes Doubles Risk of Liver Disease, Liver Cancer - Doctor's Guide, 2/13/04
• Insulin-Like Growth Factor I Has Direct Effect on Glucose and Protein Metabolism in Type 1 Diabetes - Doctor's Guide, 1/29/04 - "circulating IGF-I may act in concert with insulin to control glucose and protein metabolism" - Note:  Growth hormone increases IGF-I.
• Few With Diabetes Have Heart Risks Controlled - WebMD, 1/21/04
• New Antibiotic, Linezolid, Effective for Diabetic Foot Infections - Doctor's Guide, 1/14/04
• High Heme-iron Intake May be Associated with Increased Risk for Type 2 Diabetes - Doctor's Guide, 1/12/04
• Islet Cell Transplantation Associated with Severe Complications, Often Imperfect Glycaemia Control - Doctor's Guide, 12/9/03
• Diabetes, Are You at Risk? - Time Magazine Cover Story, 12/8/03 - "Now there are half a dozen studies confirming that if you measure markers of inflammation, and CRP in particular, you can do a good job of predicting who's going to get diabetes"
• Redefining Impaired Fasting Glucose - Physician's Weekly, 11/24/03 - "the cut point for IFG should be reduced to 100 mg/dl from the current 110 mg/dl"
• Younger Adults With Type 2 Diabetes 14 Times More Likely to Suffer Heart Attacks - Doctor's Guide, 10/24/03 - "Young adults, age 18-44, who get type 2 diabetes are 14 times more likely to suffer a heart attack and up to 30 times more likely to have a stroke than their peers without diabetes"
• Poorly Controlled Diabetes Can Lead To Liver Problems - Doctor's Guide, 10/24/03
• Extended Delay in Progression of Diabetic Nephropathy Seen in Patients who Received Intensive Diabetes Treatment - Doctor's Guide, 10/23/03
• Intensive Type 1 Diabetes Treatment Best - WebMD, 10/21/03
• Cause of Diabetes Affects Response to Treatment - Doctor's Guide, 10/20/03
• Cause of Diabetes Affects Treatment - WebMD, 10/16/03
• Anaemia in Diabetics Often Unrecognised, Undetected, and Untreated - Doctor's Guide, 10/16/03 - "Although anaemia is a key indicator of renal disease, a significant complication caused by diabetes, most diabetics are not tested for anaemia and remain unaware of an association between anaemia and kidney disease ... reduced quality of life was evident by reports of being down or depressed (21%), very down or depressed (17%), or feeling frustrated (17%)"
• Thiazolidinediones Linked to Congestive Heart Failure and Pulmonary Edema - Doctor's Guide, 10/7/03
• Obesity Linked to Type 1 Diabetes - WebMD, 9/26/03
• Indications and Management Strategies for Insulin Therapy in the Treatment of Type 2 Diabetes - Doctor's Guide, 9/8/03 - "The American Diabetes Association goals for glucose control are a haemoglobin A1c level of less than 7%, a fasting glucose level between 90 and 130 mg/dL, and a post-prandial glucose concentration of less that 180 mg/dL"
• Lizard-Spit Drug Helps in Diabetes - WebMD, 8/27/03
• Anaemia Frequently Present in Diabetes Patients but Frequently Undiagnosed - Doctor's Guide, 8/26/03
• Insulin Therapy for Early Type 2 Diabetes? - WebMD, 8/21/03
• Doctors Ignore Diabetes Guidelines - WebMD, 8/18/03 - "Do you have diabetes? There's a one-in-three chance that if you do, you don't know ... Testing should be considered at a younger age -- and done more frequently -- in certain people: ... Anyone with high blood pressure (140/90 or higher) ... Anyone with an HDL "good" cholesterol of 35 or under and/or triglyceride levels of 250 or more ... Anyone with a fasting blood sugar level of 100 to 125"
• Is it possible to prevent type 2 diabetes? - Ann Endocrinol (Paris). 2003 Jun;64(3 Suppl):37-44 - "Four prospective randomised long-term studies have been recently completed and published ... Both of them clearly demonstrate the possibility to delay and/or prevent the onset of type 2 diabetes in at high-risk subjects with impaired glucose tolerance, through changes in lifestyle (dietary intervention, weight reduction, increased physical activity) or drug treatment (metformin, acarbose, orlistat)"
• New Treatment Eases Type 2 Diabetes - WebMD, 8/6/03
• Lengthening Achilles Tendon Reduces Recurrence Of Diabetic Foot Ulcers - Doctor's Guide, 7/31/03
• First Wireless, Integrated Insulin Pump And Glucose Monitor System Receives FDA Clearance - Doctor's Guide, 7/17/03
• Impaired Glucose Tolerance Ups Cancer Deaths - WebMD, 7/11/03 - "people with impaired glucose tolerance have a high risk of cancer death ... They're nearly twice as likely to die of any form of cancer ... They're more than four times as likely to die of colon cancer ... They're more than 50% more likely to die of lung cancer"
• Patients With Diabetic Nephropathy Benefit From Combined Antihypertensive Therapy, Lower Target Blood Pressure - Doctor's Guide, 7/10/03
• Screening Strategies May Not Detect Early Renal Disease In Patients With Type 2 Diabetes - Doctor's Guide, 6/26/03
• Diabetic Kidney Disease Often Missed - WebMD, 6/24/03
• Fatty Diet Raises Diabetes Risk - WebMD, 6/20/03 - "surveys of people with diabetes have suggested a link between the amount of saturated fat in a person's diet and diabetes risk, but until now that link has not been confirmed by biological evidence ... they looked at the levels of fatty acids in the blood, which reflects how much saturated fat a person generally eats over time, and compared it to the risk of developing type 2 diabetes among a group of 2,909 adults aged 45-64 ... During nine years of follow-up, 252 of the men and women developed type 2 diabetes ... As the level of fatty acids increased, the likelihood that the person developed type 2 diabetes also increased" - This is something else the Atkin's studies should be looking at.  This study was nine years.  I believe the longest Atkin's study was one year. - Ben
• Ruboxistaurin Reduces Visual Loss in Patients with Moderate to Severe Diabetic Retinopathy - Doctor's Guide, 6/20/03
• Gastric Electrical Stimulation Might Decrease Mortality of Patients with Diabetic Gastroparesis - Doctor's Guide, 6/20/03
• Promising New Treatment Improves Glucose and Lipid Control in Type 2 Diabetes - Doctor's Guide, 6/20/03
• Study Establishes Independent Association of Lipoprotein(a) with Cardiovascular Mortality in Type 2 Diabetes - Doctor's Guide, 6/20/03
• Novel PKC b Inhibitor Ruboxistaurin Targets Diabetic Microvascular Complications - Doctor's Guide, 6/20/03
• Renal Function Decline May Begin Earlier than Expected in Type 1 Diabetics - Doctor's Guide, 6/20/03
• Large Number of Neuropathy Diagnoses Missed - Doctor's Guide, 6/19/03
• Magnetic Resonance Spectroscopy Help in Evaluation of Diabetic Feet - Doctor's Guide, 6/19/03
• Iron Stores May Predict Diabetes Risk - Doctor's Guide, 6/18/03 - "Women in the highest quintile of ferritin concentration were 2.66 times more likely to have diabetes, compared with those in the lowest quintile"
• Intensive Glycaemic Control Yields Benefits Years Later - Doctor's Guide, 6/18/03
• Synthetic Peptide, Exenatide, Shows Promise for Diabetes Even when Other Agents Fail - Doctor's Guide, 6/18/03
• Venom-Derived Drug 'Exenatide' Helps Treat Diabetes - WebMD, 6/17/03
• Anticonvulsant Topiramate May Target Underlying Diabetic Disease Process - Doctor's Guide, 6/17/03
• Peripheral Percutaneous Interventions Are Not Contraindicated in Diabetes - Doctor's Guide, 6/17/03
• Increased Hip Fractures Risk Seen in Premenopausal Women with Diabetes - Doctor's Guide, 6/17/03
• Disease Management Program Cuts Lower Extremity Amputation Rate in Diabetes Patients - Doctor's Guide, 6/17/03
• One in Three Kids Will Develop Diabetes - WebMD, 6/16/03
• Epilepsy Drug Topamax Targets Diabetes - WebMD, 6/16/03 - "In a small study, the antiepileptic drug Topamax lowered levels of total cholesterol, blood glucose, and diastolic blood pressure, all components of the "prediabetic syndrome,""
• One in Three Children Will Develop Diabetes - Doctor's Guide, 6/16/03 - "The study showed that 33% of boys and 39% of girls born in 2000 will develop diabetes in their lifetime ... The projected lifetime risk is about three times higher than the American Diabetes Association's current estimate ... With simple lifestyle changes, patients can decrease their risk of developing diabetes by more than 50%"
• Diabetics Might Be Inadequately Immunised Against Influenza and Pneumococcal Infection - Doctor's Guide, 6/16/03
• Osteoporosis Common in Diabetes Patients - Doctor's Guide, 6/16/03
• Statins Cut Diabetes Heart Risk - WebMD, 6/12/03
• Intensive Diabetes Management Slows Carotid Artery Wall Thickening - Doctor's Guide, 6/11/03
• A Diabetes Disconnect?  Technology and Empathy can Improve Patient Self-Management - Physician's Weekly, 6/9/03
• Fasting And Post-Challenge Hyperglycemia May Indicate Distinct Pathways in Progression Of Type 2 Diabetes - Doctor's Guide, 6/5/03
• Tight Glucose Control In Diabetes Lowers Risk Of Atherosclerosis - Doctor's Guide, 6/5/03
• Diabetes Health Key: Blood-Sugar Control - Doctor's Guide, 6/4/03
• Schizophrenia Drugs Linked to Diabetes - WebMD, 6/3/03 - "close to 25% of them developed high blood sugar levels while taking Clozaril, the first of these newer schizophrenia medications -- called "atypical antipsychotics." ... people with schizophrenia have a four- to six-fold risk of diabetes compared with the general population ... One possible explanation: Those with schizophrenia typically have higher levels of cortisol, known as the "stress hormone," because the body releases it during times of agitation. And high cortisol levels can cause problems in the way blood sugar is metabolized" - See my cortisol page for possible ways to reduce it.
• Erectile Dysfunction / Impotence - Prostate Health Guide - U. of Maryland Medicine - "There are 5 million adult men in the US with diabetes, and it is estimated that half are impotent and the other half will become impotent in time. The process involves premature and unusually severe hardening of the arteries. Peripheral neuropathy, with involvement of the nerves controlling erections, is commonly seen in persons with diabetes"
• Newer Insulins Analogues Prevent Hypoglycemic Episodes Compared To Conventional Insulins - Doctor's Guide, 5/20/03
• Errors Likely when Single C-Peptide Measurement Determines Diabetes Type Status - Doctor's Guide, 5/19/03
• Glycaemic Optimisation Improves Diabetic Dyslipidaemia - Doctor's Guide, 5/19/03
• Toddlers with Diabetes May Benefit from Switch to Insulin Pump Therapy - Doctor's Guide, 5/7/03
• GlucoWatch Biographer Improves Diabetes Control in Children - WebMD, 4/29/03
• Insulin Pumps Do Not Increase Autoimmunity in Type 1 Diabetic Patients - Doctor's Guide, 4/29/03
• Children Of Diabetics Show Increased Adiposity, Rapidly Progressing Insulin Resistance - Doctor's Guide, 4/24/03
• Sugar Doesn't Cause Type 2 Diabetes in Women - WebMD, 4/22/03
• Gene Therapy Cures Diabetes in Mice - WebMD, 4/21/03
• A New Glucose Monitor Built into Contact Lenses May Get Rid of Fingerpricks for People With Diabetes - WebMD, 4/16/03
• Combination Therapy Improves Management of Obese Diabetics - Doctor's Guide, 4/15/03 - "Adding rosiglitazone, an insulin-sensitising thiazolidinedione drug, to metformin, a biguanide agent, greatly enhances the management of obese type 2 diabetic patients who are inadequately controlled by metformin alone"
• Dual Renin-Angiotensin System Blockade Augments Protection In Diabetic Nephropathy - Doctor's Guide, 4/15/03
• Insulin Propeptide Levels Related To Foetal Growth, Leptin Levels - Doctor's Guide, 4/14/03
• The ABCs Of Diabetes - Time Magazine, 4/14/03
• Insulin Pump Therapy Safe, Effective in All Ages - Medscape, 4/9/03
• Diabetes Linked to Development of Alzheimer's Disease - Doctor's Guide, 4/8/03 - "people with diabetes had a 73% greater chance of developing Alzheimer s disease compared to controls ... people with diabetes had a 51% greater rate of decline in perceptual speed"
• Association Between Autoimmune Thyroid Dysfunction And Type 1 Diabetes Confirmed - Doctor's Guide, 4/8/03
• Blood Glucose Monitoring: From Measurement to Management - Physician's Weekly, 4/7/03
• Fasting Glycaemia Levels Link With Smoking History Among Diabetics - Doctor's Guide, 4/7/03
• Blood Pressure Rises Decades Before Diabetes Develops - Doctor's Guide, 4/7/03 - "Elevations in blood pressure precede the development of type 2 diabetes in middle age by 20 to 25 years"
• Topiramate Shows Promise in Patients with Diabetes and Metabolic Syndrome - Doctor's Guide, 4/2/03 - "Diabetic control (hemoglobin A1C levels) improved significantly during topiramate treatment, and the effect was dose-related ... Reductions in hemoglobin A1C did not seem to correlate with topiramate-induced weight loss ... The study also found that most patients lost weight during topiramate treatment. Eighteen to 40% of patients showed clinically significant weight loss, losing at least 5% of their baseline weight"
• Insulin Resistance, Alcohol Use Associated With Arterial Stiffness In Type 2 Diabetes - Doctor's Guide, 4/1/03
• Most Islet Cell Transplant Recipients Insulin Independent After 12 Months - Doctor's Guide, 4/1/03
• Type 2 Diabetes: Blood Pressure as Important as Blood Sugar Levels - WebMD, 3/31/03
• Low Levels Of Asymmetric Dimethylarginine In Type 2 Diabetes - Doctor's Guide, 3/31/03
• Islet Cell Transplants: Continued Success - WebMD, 3/28/03
• Dangerous Cardiovascular Complications Endanger Pregnant Diabetic Women - Doctor's Guide, 3/26/03
• Pramlintide Helpful Adjunct to Insulin in Type 2 Diabetics - Medscape, 3/20/03
• Diabetics With Severe Chronic Leg Ischaemia Tolerate Iloprost - Doctor's Guide, 3/19/03
• Standard Insulin Regimens Result In High Prevalence Of Hypoglycaemia In Prepubertal Children - Doctor's Guide, 3/18/03
• Insulin-Like Growth Factor 1 Changes Linked To Proliferative Diabetic Retinopathy - Doctor's Guide, 3/17/03
• Interleukin Combination Linked To Diabetes Risk - Doctor's Guide, 3/11/03
• Endothelial Function Impaired In Young Diabetics - Doctor's Guide, 3/6/03
• Microalbuminuria Associated With Low Polyunsaturated Fatty Acids In Type 2 Diabetes - Doctor's Guide, 3/6/03
• False Renal Function Estimates Partly Cause Severe Hypoglycaemia - Doctor's Guide, 2/19/03
• Diabetes Prevention Efforts Achieving Good Results - Doctor's Guide, 2/17/03 - "Strategies that may prevent progression to diabetes include weight reduction, exercise, insulin secretagogues, metformin, glucosidase inhibitors and thiazolidinedione ... Diabetes risk was reduced by 31% among patients who were treated with metformin (which tends to restrain weight gain) and by 58% for patients who improved their lifestyle ... Losing even 5 to 7 kg [11 to 15.4 pounds] "has an enormous benefit" that was also apparent in cholesterol and other cardiovascular risk factor reductions"
• Drug [benfotiamine] Gives Hope To People With Diabetes [with retinopathy] - Intelihealth, 2/17/03
• Vitamin [benfotiamine] Zaps Diabetes Damage - WebMD, 2/18/03
• Multifactorial Intervention Reduces Morbidity in Type 2 Diabetic - Medscape, 2/14/03
• Body Fat Distribution Linked to Diabetes - WebMD, 2/14/03
• Normal Weight Elderly Still May Be At Risk For Developing Diabetes - Doctor's Guide, 2/13/03
• Serum Angiotensin Converting Enzyme May Predict Severe Hypoglycaemia In Young Diabetics - Doctor's Guide, 2/3/03
• Oral Insulin Effective in Type 2 Diabetes - Medscape, 1/31/03
• Insulin Resistance Profoundly Effects Lipoprotein Size And Subclass Concentrations - Doctor's Guide, 1/30/03 - "Overall, more marked insulin resistance was associated with increases in the size and concentration of very low density lipoprotein (VLDL) as well as decreases in the sizes of both low density lipoprotein (LDL) and high density lipoprotein (HDL). The subgroups of insulin-sensitive and insulin-resistant subjects without diabetes also showed the association"
• Diabetic Nephropathy May Have Genetic Origins - Doctor's Guide, 1/20/03
• Young Diabetics Have High Stroke Risk - WebMD, 1/16/03
• C-Reactive Protein as a Predictor for Incident Diabetes Mellitus Among Middle-aged Men - Archives of Internal Medicine, 1/13/03 - "Low-grade systemic inflammation is associated with an increased risk of type 2 diabetes mellitus in middle-aged men. Inflammation could be one mechanism by which known risk factors for diabetes mellitus, such as obesity, smoking, and hypertension, promote the development of diabetes mellitus" - Inflammation has been associated with diabetes, arthritis, heart disease, Alzheimer's disease and stoke.  See my inflammation page for ways to reduce it.
• Pancreatic Islet Transplantation Produced Insulin Independence In Type I Diabetics - Doctor's Guide, 1/10/03
• Pramlintide Injections Improve Glycemic Control - Medscape, 1/9/03
• Type 1 Diabetics Should Be Screened for Parietal Cell Antibodies - Medscape, 1/9/03
• The Spectrum Of Association Between Coeliac Disease And Diabetes Mellitus - Doctor's Guide, 1/7/03
• HRT May Reduce Diabetes Risk - WebMD, 1/6/03 - "postmenopausal women with heart disease who took a combination of estrogen and progestin (Prempro) had a 35% lower risk of developing diabetes than those who took a placebo. The women on HRT also had more normal fasting blood sugar levels, which when high suggest the likely onset of diabetes"
• Bedtime Snacks Recommended for Diabetics with Low Nocturnal Glucose Levels - Doctor's Guide, 1/3/03
• Acute Reduction of Fatty Acids Improves Insulin Secretion in Some Type 2 Diabetics - Doctor's Guide, 1/2/03
• Diabetics Require Stringent Preventive Medicine To Aid Metabolic Control, Lower Cardiovascular Risks - Doctor's Guide, 12/16/02
• Pirenzepine Enhances Insulin Sensitivity - Doctor's Guide, 12/11/02
• Percutaneous Hepatic Implantation of Pancreatic Islet Cells Effective for Type 1 Diabetes - Doctor's Guide, 12/5/02
• Study Raises Questions About HRT In Diabetic Women - Intelihealth, 12/3/02 - "In diabetic women who hadn't experienced a recent heart attack, HRT was associated with a 16 percent lower risk of heart attack"
• Abdominal Fat Distribution Associated With Insulin Resistance In Type 2 Diabetes Mellitus - Doctor's Guide, 11/19/02
• Lowering Systolic Blood Pressure Reduces Risk of Diabetic Nephropathy Progression - Doctor's Guide, 11/7/02
• Human Fibroblast-Derived Dermis Heals Diabetic Foot Ulcers - Doctor's Guide, 11/4/02
• Diabetics Have Increased Arterial Stiffness - Doctor's Guide, 10/29/02
• Linezolid as Effective as Traditional Treatment for Diabetic Foot Infections - Doctor's Guide, 10/28/02
• Flexible Insulin Management Improves Quality of Life in Diabetes - Medscape, 10/8/02
• A New Way to Control Type 1 Diabetes - WebMD, 10/3/02
• Adjusting Insulin To Match Food A Success In Type 1 Diabetics - Doctor's Guide, 10/4/02
• Mechanisms Explain How Exercise Helps Diabetic, Hypertensive Cardiovascular Health - Doctor's Guide, 10/3/02
• Diabetic Women On Hormone Replacement Therapy Have Better Glycemic And Lipid Profiles - Doctor's Guide, 9/26/02
• Unified, Multidiscipline Team Approach To Wound Care May Reduce Amputations Among Diabetics - Doctor's Guide, 9/25/02
• Thiazolidinediones and Fluid Retention: Prevalence and Tolerability in Patients with Chronic Heart Failure - Doctor's Guide, 9/24/02
• Temperature Monitoring Device can Help Prevent Diabetic Foot Complications - Doctor's Guide, 9/5/02
• Simvastatin Protects against Endothelial Dysfunction in Type 2 Diabetes - Doctor's Guide, 9/5/02
• High Protein Diet Helps Control Blood Glucose in Untreated Type 2 Diabetics - Doctor's Guide, 9/5/02
• Low-Dose Acetylsalicylic Acid may Interfere With ACE Inhibition in Type I Diabetics - Doctor's Guide, 9/4/02 - "Low-dose acetylsalicylic acid (ASA, Aspirin) may increase systolic blood pressure in type 1 diabetic patients, especially in those taking angiotensin-converting enzyme (ACE) inhibitors ... Compared to those not taking ASA, patients taking ASA had higher systolic blood pressure (SBP) (151 plus or minus 1 versus 134 plus or minus 1 mmHg; p<0.0001) and diastolic blood pressure (DBP) (84 plus or minus 1 versus 80 plus or minus 1 ... Similarly, in patients without CVD and not taking antihypertensive drugs (n=37), SBP was still higher in those taking ASA (142 plus or minus 3 mmHg) compared to the 1042 participants who were not taking it (128 plus or minus 1 mmHg)"
• High-Intensity Resistance Training Improves Glycaemic Control in Elderly with Type 2 Diabetes - Doctor's Guide, 9/4/02
• Adding Acarbose to Lispro Helps Prevent Postprandial Blood Glucose Excursions in Type 2 Diabetics - Doctor's Guide, 9/3/02
• Poor Nutrition In Infancy May Lead To Development Of Type 2 Diabetes - Doctor's Guide, 8/29/02
• Acarbose Boosts Glibenclamide's Glucose Lowering Effect, Lowers Risk Of Hypoglycaemia For Type 2 Diabetics - Doctor's Guide, 8/28/02
• Orlistat Shown to Cut Diabetes Risk - Doctor's Guide, 8/27/02
• Landmark XENDOS Study Shows Xenical (Orlistat) Significantly Prevents Or Delays The Development Of Type 2 Diabetes - Doctor's Guide, 8/26/02
• Practical Stress Management Program Found To Improve Health Of People With Type 2 Diabetes - Doctor's Guide, 8/26/02
• Treating diabetics' depression may improve physical health - USA Today, 8/25/02
• Iridium-192 Intracoronary Radiation Reduces Risk of Recurrent Coronary Restenosis in Diabetics - Doctor's Guide, 8/22/02
• Triple Oral Antidiabetic Therapy Effective for Long-term Management of Type 2 Diabetes - Doctor's Guide, 8/22/02
• Miglitol Lowers HbA1c and Postprandial Glucose and Insulin Levels in Type 2 Diabetics Treated by Diet Alone - Doctor's Guide, 8/21/02
• Diabetic Men Above Age 50 Face Higher Risk Of Erectile Dysfunction - Doctor's Guide, 8/8/02
• Moderate Alcohol Consumption May Increase Atherosclerosis Risk In Diabetics - Doctor's Guide, 8/7/02
• Doctors Treat Diabetes Personally - Intelihealth, 8/6/02
• Increased Inflammation May Play A Role In Vascular Dysfunction In Type 2 Diabetes - Doctor's Guide, 8/1/02
• Low Dose Valsartan Therapy May Reduce Urinary Albumin Excretion In Type 2 Diabetics With Nephropathy - Doctor's Guide, 7/31/02
• Extended-Release Niacin Safe, Effective in Type 2 Diabetes - Medscape, 7/26/02
• Substituting Saturated Fat For Starch In Diets Type 2 Diabetics May Help With Glycemic Control And Weight Loss - Doctor's Guide, 7/24/02
• Diabetes May Be Long-Term Risk Factor for Alzheimer's Disease - Doctor's Guide, 7/24/02
• Hypertension, Albuminuria Inadequately Managed in Diabetics - Doctor's Guide, 7/19/02
• Islet Transplantation Offers Reasonable Option for Diabetics with Severe Glycemic Lability or Hypoglycemia - Doctor's Guide, 7/18/02
• Women With Type 2 Diabetes At Elevated Risk of Cardiovascular Disease Even Before Diagnosis - Doctor's Guide, 7/17/02
• Non-Dipping In Diabetics Due To Blunted Effect Of Sleep Itself - Doctor's Guide, 7/2/02
• Sleeping With Lights On May Stave Off Diabetic Retinopathy - Doctor's Guide, 7/1/02
• Light at Night Protects Diabetics' Eyes - WebMD, 6/27/02
• Cozaar (Losartan) Lowered Risk Of Total Mortality In Patients With Diabetes By 39% Versus Atenolol - Doctor's Guide, 6/27/02
• Vestibular Organ Impairment Occurs In Type 1 Diabetes - Doctor's Guide, 6/25/02
• Painless Blood-Sugar Tests in the Works - WebMD, 6/19/02
• Post-Challenge Glucose Levels Correlated Directly to Cardiovascular Outcomes - Doctor's Guide, 6/19/02
• Orlistat Found Beneficial in Type 2 Diabetics with Differing Hemoglobin A1c Levels - Doctor's Guide, 6/19/02
• Survey Suggests That Many Diabetics Lack Concern About Long-Term Complications - Doctor's Guide, 6/18/02
• Sibutramine Effective For Diabetics In Association With Weight Loss Program - Doctor's Guide, 6/18/02
• More Efforts Needed to Improve Cardiovascular Burden in Diabetes, Say Researchers - Doctor's Guide, 6/18/02
• New Ways to Take Insulin - WebMD, 6/18/02
• When Managing Diabetes, Good Glycemic Control Is Not Enough - Medscape, 6/17/02
• Kids Headed for Diabetes Disaster - WebMD, 6/16/02
• Xenical (Orlistat) Helps Maximally-Medicated Diabetics Avoid Insulin - Doctor's Guide, 6/17/02
• Risk Factors Boost Pregnancy Diabetes Prevalence Risk Six-Fold - Doctor's Guide, 6/17/02
• Fragmin (Dalteparin) Injections Help Heal Diabetic Foot Ulcers - Doctor's Guide, 6/17/02
• Pramlintide Reduces Postprandial Excursions in Diabetics - Doctor's Guide, 6/17/02
• Exubera (Inhaled Insulin) Provides Better Glycemic Control Than Oral Therapy For Patients With Type 2 Diabetes, New Data Show - Doctor's Guide, 6/17/02
• Xenical (Orlistat) Improves Post-prandial Glucose Levels in Obese Diabetics - Doctor's Guide, 6/16/02
• Rosiglitazone Added to Glyburide/Metformin Helps Tough-to-Treat Diabetics - Doctor's Guide, 6/16/02
• Vardenafil Provides Sustained Improvement of Erectile Dysfunction in Men with Diabetes - Doctor's Guide, 6/16/02
• Diabetics Have High Incidence of Preventable Blinding Diseases - Doctor's Guide, 6/16/02
• Better Lipid Management Needed in Patients with Diabetes and Heart Disease - Doctor's Guide, 6/16/02
• Pramlintide Decreases Glucose Fluctuations in Diabetics Treated with Insulin Pumps - Doctor's Guide, 6/16/02
• When Managing Diabetes, Good Glycemic Control Is Not Enough - Medscape, 6/17/02
• Acarbose May Delay Development Of Type-2 Diabetes - Doctor's Guide, 6/14/02
• Drug [Precose] Helps Prevent Type 2 Diabetes - WebMD, 6/13/02
• FDA Approves Diabetes Monitors - Intelihealth, 6/13/02
• Education Helps Reduce Elevated Glycosylated Haemoglobin Levels - Doctor's Guide, 6/11/02
• Aspirin May Improve Glucose Tolerance In Type 2 Diabetes Through Serine Kinase Inhibition - Doctor's Guide, 6/4/02
• High Hostility Levels and Stress May Boost Risk for Type 2 Diabetes - Clinical Psychiatry News, 6/02
• Insulin Falls Short Of Target In Large Diabetes Prevention Trial - Doctor's Guide, 5/30/02
• New Immune Suppressive Drug [hOKT3g1(Ala-Ala)] May Curb Onset Of Type 1 Diabetes - Doctor's Guide, 5/30/02
• Drug Stops Type 1 Diabetes in Its Tracks - WebMD, 5/29/02
• Insulin Fails First Test As Diabetes-Preventing Drug - Intelihealth, 5/29/02
• Diabetic Children At High Risk For Ketoacidosis, Hypoglycaemia - Doctor's Guide, 5/22/02
• Retinal Arteriolar Narrowing Predicts Diabetes Risk In Middle-Age - Doctor's Guide, 5/21/02
• New cell infusion a 'miracle' for diabetics - USA Today, 5/16/02
• Diabetic Footwear Debunked - WebMD, 5/14/02
• Alcohol Lowers Diabetes Risk in Women - WebMD, 5/14/02
• Promising New Treatment for Early Type 2 Diabetes - Medscape, 5/10/02
• Pulse Oximetric Toe Pressure Useful In Detecting Peripheral Arterial Disease In Diabetics - Doctor's Guide, 5/9/02
• Combination Therapy Best For Diabetics With Higher Glycemic Levels - Doctor's Guide, 5/6/02
• Diabetic Toddlers Can Use Insulin Pumps - WebMD, 5/6/02
• Chicken Diet Better Than Red Meat in Type 2 Diabetes - Medscape, 4/29/02
• Conventional Diet, Exercise Yields More Sustained Weight Loss in Type 2 Diabetes - Doctor's Guide, 4/26/02
• Americans with diabetes learn to eat well, exercise - USA Today, 4/16/02
• Diabetes Patients Not Getting Proper Care - WebMD, 4/15/02
• Knowing Your Diabetes Risk - WebMD, 4/15/02
• Wristwatch tracks diabetics' blood sugar - USA Today, 4/15/02
• Increased Protein And Reduced Fat Has No Significant Effect On Weight Loss Among Type 2 Diabetics - Doctor's Guide, 4/11/02
• 'Pre-Diabetes' Puts Millions at Risk - WebMD, 3/28/02 - "The threat of an epidemic of diabetes is now so great that the U.S. government has created a whole new condition for those at risk, called "pre-diabetes." ... Research shows that most people with pre-diabetes will develop diabetes within a decade unless they make changes in their lifestyle, such as eating a healthier diet and becoming more physically active"
• Medical experts warn of the dangers of 'prediabetes' - USA Today, 3/28/02
• More Tests For "Pre-Diabetes" Urged - Intelihealth, 3/28/02
• Moderate Aerobic Exercise May Have Little Effect On Insulin Sensitivity In Obese Diabetics - Doctor's Guide, 3/27/02
• Concise Update to Managing Adult Diabetes - Medscape, 3/21/02
• Drug for high blood pressure reduces diabetes risk - CNN, 3/21/02 - "using the drug Cozaar to treat people with high blood pressure reduces their risk of developing diabetes by 25%"
• Retrospective Study Indicates Glitazones Increase Risk For Heart Failure In Diabetics - Doctor's Guide, 3/19/02
• New Diabetes Drugs Still Pose Liver Risks - WebMD, 3/19/02
• Obese Kids at Risk for Diabetes - WebMD, 3/13/02
• Cilostazol May Prevent Silent Brain Infarction In Type II Diabetics - Doctor's Guide, 3/12/02
• Hormonal Diabetes Treatment Shows Promise - WebMD, 3/7/02
• Hot Dogs, Lunch Meats Raise Diabetes Risk - WebMD, 3/1/02
• Diabetes Drug [Glucophage] Helps Prevent Miscarriage - WebMD, 3/1/02
• Diabetic Women Often Poor - Intelihealth, 2/21/02
• Plasma Nitric Oxide Levels Less Important Than Neuropathy In Recurrent Diabetic Foot Ulcers - Doctor's Guide, 2/20/02
• Most Diabetics Unaware of Heart Risk - WebMD, 2/20/02
• Many diabetics unaware of heart disease link - CNN, 2/19/02
• Western Diet Substantially Increases Risk For Type 2 Diabetes In Men - Intelihealth, 2/14/02
• Guidelines Focus on Controlling Glucose in Diabetes, Not Diet - Medscape, 2/13/02
• Diabetics Can Have Cake and Eat It, Too - WebMD, 2/12/02
• Most Adult Diabetics In United States Have Hypertension - Doctor's Guide, 2/4/02
• 1/3 of Diabetic Men Have Impotence - WebMD, 2/1/02
• Gastric band improves weight, blood sugar - USA Today, 1/28/02
• Tests Begin for Diabetes 'Cure' [INGAP peptide] - WebMD, 1/18/02
• Diabetes Reduces Lower Extremity Function In Patients With Peripheral Artery Disease - Doctor's Guide, 1/18/02
• Nodding Off? 'Wake-Up Pills' Available - WebMD, 1/16/02 - "Studies at the University of Chicago show that when college-aged men were allowed to sleep for just four hours a night for one week, their insulin reactions were that of "old diabetics,""
• Do You Have Metabolic Syndrome? - WebMD, 1/15/02
• Stress Management Can Help Control Glucose In Type 2 Diabetes - Doctor's Guide, 12/27/01
• New Guidelines Allow Some Sweets For Diabetics - Intelihealth, 12/27/01
• Diabetes Drug [Glucophage/metformin] May Fight Obesity - WebMD, 12/26/01 - "Pediatricians at the University of Tennessee School of Medicine put 24 obese adolescents on a low-calorie diet: 1,500 calories a day for the girls and 1,800 calories a day for the boys. They also gave half the teens Glucophage and half a placebo ... After eight weeks, dieting teens who took the placebo lost 3.8 % of their body weight. But those taking Glucophage lost 6.5 % of their body weight -- nearly twice as much"
• Diabetic Patients on Statins Experience Fewer Lower Extremity Infections - Doctor's Guide, 12/19/01
• Irregular periods linked to diabetes - USA Today, 11/20/01
• Amputations Can Be Sidestepped With the Right Footwear - WebMD, 11/7/01
• Amputation: Grisly Risk for Diabetics - WebMD, 11/6/01
• Blood Pressure Drug May Help Kidneys - Intelihealth, 9/19/01
• Xenical Drops Weight, Blood Sugar in Diabetics - WebMD, 9/12/01
• Insulin Aspart Safe During Long-Term Treatment - Doctor's Guide, 9/11/01
• Insulin Glargine Produces Less Symptomatic Hypoglycemia Than NPH Insulin In Type-2 Diabetes - Doctor's Guide, 9/11/01
• Millions Of 30-Somethings Urged To Get Diabetes Tests As Disease Strikes Young Adults - Intelihealth, 8/28/01 - "the fatter you are, the more likely Type 2 diabetes is to strike before age 45 - as young as 18. Obesity not only was key to early diabetes, but the risk rose 6 percent for every 5 pounds to 8 pounds (2 to 4 kilograms) of extra weight"
• New Diabetes Guidelines Focus on Prevention, Treatment - WebMD, 8/21/01
• Overweight, Obese Kids Headed for Diabetes - WebMD, 8/14/01
• How to Avoid Diabetes -- Landmark Results Unveiled - WebMD, 8/8/01 - "Either a low-fat diet combined with moderate exercise or the drug metformin -- brand name Glucophage -- dramatically reduced type 2 diabetes risk among overweight people with elevated blood sugar"
• Hormone Produced By Fat Cells May Help Fight Insulin Resistance In Diabetics - Intelihealth, 7/31/01
• Cow's Milk May Cause Type 1 Diabetes in at-Risk Infants - WebMD, 7/23/01 - "Those fed the formula made without cow's milk were about 50% less likely to develop proteins that are associated with type 1 diabetes"
• Evidence Builds for Use of Glycemic Index to Control Diabetes - WebMD, 7/19/01
• Another Study Suggests Inflammation May Trigger Diabetes - WebMD, 7/17/01 - "The immune system and inflammation may be factors causing type 2 diabetes ... women who had high levels of immune system substances called C-reactive protein or interleukin-6, or both, in their blood were more likely to develop type 2 diabetes ... Both C-reactive protein, called CRP, and interleukin-6, or IL-6, are considered indicators for inflammation"
• Caution Urged For Diabetics Using Selective Serotonin Reuptake Inhibitors - Doctor's Guide, 7/9/01
• Accurate Blood Sugar Readings Are at Your Fingertips - WebMD, 7/6/01
• Reversing Type 1 Diabetes - WebMD, 6/27/01
• As waistlines expand, so will cases of type 2 diabetes - USA Today, 6/26/01
• New insulin may make shots a sting of the past - CNN, 6/25/01
• Depressive Symptoms In Diabetics Worsen Glycemic Control - Doctor's Guide, 6/25/01
• Glyburide/Metformin Combination Helps Maintain Long-Term Blood Sugar Control - Doctor's Guide, 6/26/01
• Insulin Lispro Controls Diabetes In Pregnant Women - Doctor's Guide, 6/25/01
• Sleep on This: Lack of Shut-Eye Ups Diabetes Risk - WebMD, 6/25/01 - "People who don't get adequate rest may increase their risk for type 2 diabetes ... "short-sleepers," or those who slept less than 6.5 hours per night, were about 40% less insulin-sensitive than normal sleepers, those who logged about 7.5 to 8.5 hours a night"
• Orlistat (Xenical) Benefits Overweight Diabetics Receiving Insulin Therapy - Doctor's Guide, 6/24/01
• Measuring Blood Sugar: The Eyes Have It, New devices promise no pain, big gain for managing diabetes - WebMD, 6/24/01
• Insulin Shot Fails to Stop Diabetes -- But Insulin Pill Might Do the Trick - WebMD, 6/24/01
• Irbesartan Delays Nephropathy In Diabetic Patients - Doctor's Guide, 6/17/01
• New Treatments for Diabetes to Be Unveiled - WebMD, 6/21/01
• 'Bad' Fats Found in Processed Foods Linked to Diabetes Risk - WebMD, 6/8/01 - "Fats known as trans fatty acids, commonly seen in these foods, already have been linked to heart disease and high cholesterol. Now a study from the Harvard School of Public Health suggests that limiting their consumption also can greatly lower diabetes risk"
• People With Type 2 Diabetes at Increased Risk for Heart Attack, Stroke - WebMD, 6/1/01
• ECO: Doctors Need to Screen for Diabetes in Obese Patients - Doctor's Guide, 6/1/01
• Orlistat (Xenical) Plus Reduced Calorie Diet Beneficial For Obese Non-Diabetics - Doctor's Guide, 5/31/01
• Cozaar (Losartan) Significantly Reduces Progression of Kidney Disease in Type 2 Diabetics - Doctor's Guide, 5/24/01
• Diabetes Care: Moving Beyond Insulin, New Research Looks at Other Hormones - WebMD, 5/24/01
• Depression may double diabetes risk - USA Today, 5/24/01 - "But, even "independent of weight gain and other factors," Lustman says, depression doubles the risk for diabetes. "There are changes in hormones that occur during depression that can directly increase insulin resistance.""
• Norvasc (Amlodipine Besylate) Valuable For Treating High Blood Pressure in Diabetics - Doctor's Guide, 5/22/01
• Lantus (Insulin Glargine [rDNA Origin] Injection) Once-A-Day Treatment for Diabetes Available in US - Doctor's Guide, 5/22/01 - "first and only insulin analog that provides 24-hour glucose lowering activity with just one shot"
• Atorvastatin Lowers C-Reactive Protein In Mixed And Diabetic Dyslipidemia - Doctor's Guide, 5/21/01
• Diabetics Get Kidney Protection From ARBs, High Blood Pressure Drugs Reduce Need for Dialysis, Transplant - WebMD, 5/20/01 - "results from three landmark studies of almost 4,000 diabetic patients suggest that a specific class of blood pressure drugs called angiotensin receptor blockers, or ARBs, can protect kidneys and reduce the need for kidney dialysis or transplant"
• Irbesartan Slows Kidney Disease In Diabetics - Doctor's Guide, 5/20/01
• Inhaled Insulin as Good as Injections for Diabetics, Powder Controls Blood Sugar Without Side Effects - WebMD, 5/20/01 - "Inhaled insulin appears to work as well as the [skin-injected] insulin on blood sugar control during these three-month studies"
• White Coat Hypertension Linked To Insulin Resistance - Doctor's Guide, 5/18/01
• Diovan (Valsartan) Effective in Reducing Microalbuminuria - Doctor's Guide, 5/17/01 - "Diovan® (valsartan), is more effective in reducing microalbuminuria (p<0.001), an early sign of diabetic kidney disease, compared to the calcium channel blocker, amlodipine"
• Newer Designer Insulins Allow Diabetics to Take Control - Doctor's Guide, 5/11/01
• Diabetics' odds of survival lengthen - USA Today, 4/26/01
• Structured Training Program Helps Diabetics Keep Blood Sugar in Control - WebMD, 4/20/01
• Blood Pressure Control May Be Key In Preventing Cardiovascular Disease In Diabetics - Doctor's Guide, 4/20/01 - "Controlling blood pressure may be the key factor in preventing cardiovascular disease in people who have diabetes, and ACE inhibitors appear the best means to that end"
• ACE Scores High In Diabetic Hypertension - Intelihealth, 4/20/01 - "hypertension is twice as frequent in diabetics, and up to 75 percent of CVD cases in people with diabetes may be attributable to hypertension ... suggest that ACE inhibitor therapy may improve insulin sensitivity and also delay the development of diabetes in patients at high risk ... Rigorous control of blood pressure to less than 130 millimeters of mercury (mmHg) systolic and 85 mmHg diastolic strikingly decreases heart attacks, strokes and end-stage renal disease in diabetic patients"
• ACE Inhibitor Drugs Called Best Weapon in Fight Against Heart Disease and Diabetes - WebMD, 4/19/01
• Long-Term Blood Pressure Control Decreases Incidence Of Diabetic Retinopathy - Doctor's Guide, 4/6/01 - "DR affects 70-100 percent of patients with diabetes ... the results of this study highlight the importance of using multiple agents in order to achieve and sustain a satisfactory reduction in BP in patients with diabetic renal disease"
• Antihypertensive Control Needed To Delay Progression Of Diabetic Neuropathy - Doctor's Guide, 4/6/01 - "Proper control of blood pressure is the single most important factor in delaying the progression of diabetic neuropathy ... majority of such patients require more than a single antihypertensive agent to achieve adequate BP control (£ 130/80)"
• Angiotensin II Antagonist Telmisartan Fights Stiffening Arteries In Hypertensive Diabetics - Doctor's Guide, 4/6/01 - "not only effectively lowered blood pressure compared with placebo, but also significantly decreased arterial stiffness"
• Angiotensin II Antagonist Plus Conventional Treatment Improves Blood Pressure Control, Kidney Function - Doctor's Guide, 4/6/01 - "Adding candesartan cilexetil to conventional therapy significantly reduced albuminuria by a mean of 25 percent, fractional albumin clearance by a mean of 35 percent, 24-hour systolic blood pressure by a mean of 10 mmHg, and GFR by a mean of 5 ml/minute/1.73 m2. The mean reduction in diastolic blood pressure (3 mmHg) was not statistically significant"
• Less Risk Of Nocturnal Hypoglycemia With Lantus (Insulin Glargine) Than Neutral Protamine Hagedorn - Doctor's Guide, 4/5/01
• Metformin Outperforms Other Oral Agents In Diabetics With Severe Coronary Disease - Doctor's Guide, 3/22/01
• FDA approves watch-like diabetes monitor - USA Today, 3/22/01 - "checks glucose levels every 20 minutes by sending tiny electric currents through the skin ... it sounds an alarm if blood sugar hits dangerous levels — possibly life-saving if glucose plummets while they sleep ... prescription-only" see http://www.glucowatch.com/
• Predicting Who Will Get Diabetes, Two Tests May Help Doctors Pinpoint Warning Signs - WebMD, 3/14/01
• Pioglitazone Effectively Reduces Blood Glucose Levels In Type 2 Diabetes - Doctor's Guide, 3/9/01
• Study Explains Why Diabetics Face High Risk From Angioplasty - WebMD, 3/5/01
• Health Focus: The Implanted Insulin Pump - Intelihealth, 2/28/01
• A 'Spoonful of Sugar' May Be Acceptable for Some Diabetics - WebMD, 2/15/01
• Aspirin Greatly Underutilized Among Patients with Diabetes - WebMD, 2/13/01 - "A simple aspirin is one of the cheapest and most widely available therapies for preventing life-threatening complications of diabetes"
• Study: Inhaler as Effective as Injections, New Form of Giving Insulin Reduces Injections to One at Bedtime - WebMD, 2/1/01
• Diabetes, Obesity Becoming Epidemic - Intelihealth, 1/26/01
• Thirty-Something Diabetes Explosion, Too Much Fast Food -- and Too Little Exercise -- on the Fast Track - WebMD, 1/25/01
• Diabetic Treatment Sometimes Fatal - Intelihealth, 1/25/01
• Adult Diabetes in Kids? Heavier Kids Creating a Big Problem, Disease Trend Raises Fears of Heart Attacks at Age 30 - WebMD, 1/18/01
• New Hormone Might Explain Link Between Diabetes and Obesity - WebMD, 1/17/01
• Men Who Drink Moderately Have a Lower Risk of Diabetes, But Heavy Drinking Raises the Odds of Developing the Disease - WebMD, 1/11/01
• Afternoon Blood Tests May Miss Diabetes Diagnosis, Be Sure With Early Morning Test - WebMD, 12/26/00
• FDA Approves New Diabetes Drug (Starlix) - Intelihealth, 12/23/00
• Men Who Drink Moderately Have a Lower Risk of Diabetes - WebMD, 12/3/00
• Nateglinide Appears To Reduce HbA(1c) Comparable to Metformin - Doctor's Guide, 11/17/00
• Insulin Resistance Can Predict Hypertension Development - Doctor's Guide, 11/15/00
• U.S. says some SmithKline Avandia claims misleading - CNN, 11/1/00
• Oral Drug May Control Pregnancy-Related Diabetes - WebMD, 10/18/00
• Got Diabetes? Better Watch Your Mouth! Diabetics Need to Carefully Monitor Their Dental Health - WebMD, 9/18/00
• Diabetics on Glucophage, Listen Up, What Diabetes Drug Takes Away, Daily Supplement Puts Back - WebMD, 9/17/00
• More aggressive treatment urged for diabetics with high blood pressure - CNN, 8/29/00
• Diabetics Urged: Drop Blood Pressure - Intelihealth, 8/29/00
• Study Looks at Whether Liposuction Has an Anti-Diabetes Bonus - WebMD, 8/25/00
• Slight Weight Loss Reduces Diabetes Risk Dramatically - WebMD, 8/21/00
• Diabetes patients, researchers temper hope for quick cure - CNN, 8/14/00
• Report: Viagra May Aid Diabetics - Intelihealth, 8/2/00
• FDA Approves New Diabetes Drug - Intelihealth, 8/2/00
• Experts urge more aggressive testing, treatment of diabetes - CNN, 8/1/00
• Study: Moderate drinking protects diabetics from heart disease - CNN, 8/1/00
• Childhood Diabetes: Is Diet a Major Culprit? - WebMD, 6/30/00
• Help Is Here for Out-of-Control Diabetes - WebMD, 6/30/00
• Bad News for Babies Born to Diabetic Moms - WebMD, 6/19/00
• High Cholesterol, High Blood Pressure Often Neglected in Diabetics - WebMD, 6/16/00
• Scientist Examine Link Between Diabetes, Depression - Intelihealth, 6/16/00
• Insulin Pump Better Than Multiple-Shot Regimen for Diabetics - WebMD, 6/8/00
• Promising Diabetes Treatment Not for Everyone - WebMD, 6/6/00
• Some Diabetics Freed From Insulin Ball and Chain - WebMD, 6/6/00
• Diabetic Kids Might Benefit From Nighttime-Only Insulin Pump - WebMD, 5/26/00
• In the Blood of Diabetics, Pressure May Be More Important Than Sugar - WebMD, 5/18/00
• With Cell Transplants, Diabetics Able to Stop Insulin Shots - WebMD, 5/19/00
• Diabetic? Kick the Habit Sooner Than Later - WebMD, 5/15/00
• Activity May Keep Diabetics Alive - Intelihealth, 5/1/00
• FDA Approves Once-Daily Lantus (Insulin Glargine) For Diabetes - Doctor's Guide, 4/24/00
• Coronary Bypass Better Than Angioplasty In Protecting Diabetics From Heart Attack Death - Doctor's Guide, 4/6/00
• Study: Drug Aids Diabetes Medicine - Intelihealth, 4/5/00
• Avandia (Rosiglitazone) And Glucophage (Metformin) Combo May Slow Type 2 Diabetes Progression - Doctor's Guide, 4/5/00
• FDA Approves Avandia (Rosiglitazone) In Combo Therapy For Type 2 Diabetes - Doctor's Guide, 4/4/00
• Common blood pressure drug increases the risk of diabetes - CNN, 3/29/00 - "A drug [beta-blockers] commonly used to treat high blood pressure increases the risk of developing diabetes by 28 percent"
• Air Force study further supports Agent Orange, diabetes link - CNN, 3/28/00
• Diabetics Have Better Outcomes If They See Specialists - Doctor's Guide, 3/23/00
• Control Of Mealtime Glucose Spikes Reduces Risk Of Diabetic Complications - Doctor's Guide, 3/17/00
• Retinal Screenings For Diabetics Provide Only Marginal Benefits - Doctor's Guide, 2/16/00
• Good Sugar Control Results in Few Diabetic Complications For Type 1 Diabetics - Doctor's Guide, 2/10/00
• Aggressive therapy benefits diabetic patients - CNN, 2/9/00
• Endocrinologists Caution Against Misinterpretations Of Reports Concerning Avandia - Doctor's Guide, 1/28/00
• Diabetics At High-Risk For Heart Attack Or Stroke Benefit From Ramipril - Doctor's Guide, 1/28/00
• Memantine Significantly Reduces Peripheral Neuropathy Pain In Diabetics - Doctor's Guide, 1/25/00
• Ramipril Reduces Risk Of Cardiovascular Disease In Diabetics - Doctor's Guide, 1/21/00
• Good Insulin Mixing Technique Improves Glycemic Control - Doctor's Guide, 11/5/99
• Diabetes Therapy May Impair Memory Function In Children - Doctor's Guide, 10/4/99
• Ramipril Reduces Risk Of Heart And Kidney Complications In Diabetics - Doctor's Guide, 10/4/99
• Combination Therapy Needed To Control Hypertension In Type 2 Diabetics - Doctor's Guide, 10/1/99
• Researchers Report Enhanced Insulin Response With Exendin-4 In Type 2 Diabetes - Doctor's Guide, 9/30/99
• Cerivastatin Helps Improve Lipid Profile In Diabetics - Doctor's Guide, 9/30/99
• Type 2 Diabetics Not Taking Their Meds, Research Shows - Doctor's Guide, 9/29/99
• Type 2 Diabetics Who Quit Oral Drugs Face Significant Health Risks - Doctor's Guide, 9/29/99
• Pioglitazone Causes Few, If Any, Drug Interactions - Doctor's Guide, 9/29/99
• Orlistat Offers Double Benefits To Obese Diabetics - Doctor's Guide, 9/29/99
• Beta Cell Failure Gets Almost All Type 2 Diabetics In Time - Doctor's Guide, 9/29/99
• Pioglitazine Corrects Lipid Imbalance While Lowering Plasma Glucose - Doctor's Guide, 9/29/99
• Rosiglitazone Works By Reducing Insulin Resistance - Doctor's Guide, 9/28/99
• Nateglinide Lowers Glucose Spikes, Improves Glycemic Control - Doctor's Guide, 9/28/99
• Nateglinide Restores Early Insulin Secretion - Doctor's Guide, 9/28/99
• Cause of type-I diabetes found, researchers say - CNN, 8/30/99
• Symlin Shows Positive Results In Type 2 Diabetes Study - Doctor's Guide, 8/31/99
• Apligraf More Effective Than Standard Care For Diabetic Foot Ulcers - Doctor's Guide, 8/25/99
• Study: Moderate Drinking Heart-Healthy For Diabetics, Too - Intelihealth, 7/21/99
• FDA Approves Velosulin BR For Diabetes Treatment - Doctor's Guide, 7/20/99
• Actos Approved By FDA For Type II Diabetes - Doctor's Guide, 7/16/99
• Insulin Aspart More Effective Than Human Insulin For Type I Diabetics - Doctor's Guide, 6/22/99
• Combination Therapy With Prandin Effective For Type II Diabetics - Doctor's Guide, 6/22/99 
• Avandia Shows Promising Results In Combination Therapy - Doctor's Guide, 6/21/99
• Impaired Glucose Tolerance Linked To Early Death - Doctor's Guide, 6/21/99
• Hypertension The Most Significant Risk For Diabetics - Doctor's Guide, 6/21/99
• Troglitazone Successful As Combination Therapy For Diabetics - Doctor's Guide, 6/21/99
• Diabetics Not Using Aspirin To Prevent Heart Disease - Doctor's Guide, 6/21/99
• Avandia Reduces Insulin Resistance, Lowers Blood Sugar - Doctor's Guide, 6/15/99
• Rosiglitazone Offers Positive Results In Type 2 Diabetes - Doctor's Guide, 6/15/99
• Diabetics Improve Health With Very High-Fat, Low Carb Diet - Doctor's Guide, 6/15/99
• New research could lead to cure for juvenile diabetes - CNN, 6/2/99
• Drugs More Effective Than Diet To Maintain Blood Sugar In Type II Diabetics - Doctor's Guide, 6/1/99
• New Diabetes Drug, With Fewer Risks, May Be Available Soon - Intelihealth, 4/23/99
• FDA Advisory Committee Recommends Avandia For Type 2 Diabetes - Doctor's Guide, 4/23/99
• Diovan Reduces Microalbuminuria In Patients With Type 2 Diabetes - Doctor's Guide, 4/23/99
• Researchers Find Improved Treatment For Diabetes Complications - Doctor's Guide, 2/19/99
• A dramatic rise in the rate of diabetes reported - CNN, 6/15/98
• Treating Depression In Diabetics Helps Control Blood Sugar - Doctor's Guide, 6/6/97

Related Searches:

• Doctor's Guide search of diabetes
• Doctor's Guide (2) search of diabetes
• Intelihealth search of diabetes
• Life Extension Foundation search
• Medline search of diabetes
• Medscape search of diabetes
• Google search of diabetes
• The Natural Pharmacist search of diabetes
• Nutrition Science News search
• WebMD search of diabetes

Related Sites:

• Alteon
• Kids Learn About diabetes
• Medscape diabetes news page
• Doctor's Guide diabetes news page
• Intelihealth diabetes news page
• WebMD diabetes news page

Recommended Reading:

• Books on diabetes - Amazon.com
• American Diabetes Association Complete Guide to Diabetes : The Ultimate Home Diabetes Reference -- Philip E. Cryer; Mass Market Paperback
• Dr. Bernstein's Diabetes Solution : A Complete Guide to Achieving Normal Blood Sugars -- Richard K., MD Bernstein, et al; Hardcover
• 101 Nutrition Tips for People With Diabetes (Amer Diabetes Assn) -- Patti B. Geil MS RD FADA CDE, et al; Paperback

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