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Home > Health Conditions > Constipation.

Constipation

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  • Oligofructose Provides Laxation for Irregularity Associated with Low Fiber Intake - Nutrients. 2017 Dec 18;9(12) - "The present study is a randomized control trial that included healthy adult participants with ≤3 bowel movements/week and a habitual low dietary fiber intake in a parallel design to evaluate the benefits for laxation by supplementing the daily diet with oligofructose (Orafti® P95; OF), a fermentable source of fiber and established prebiotic (n = 49); maltodextrin was the placebo (n = 48). After a run-in phase, OF was initially provided at 5 g/day, then increased to 10 and 15 g/day with four weeks for each phase. Stool frequency (bowel movements per week) for the OF and maltodextrin (MD) groups were initially similar (3.98 ± 1.49 vs. 4.06 ± 1.48), did not change for the placebo group, but increased for the OF group with the difference significant at 15 g/day (p = 0.023). Stool consistency was similar and remained unchanged at all doses for both groups. Gastrointestinal sensations were low for both groups. Laxation benefits were especially pronounced for participants with >13 g/day habitual dietary fiber intake, with significant laxation at 10 g and 15 g OF/day (p = 0.04 and p = 0.004, respectively)" - [Nutra USA] - See oligofructose at Amazon.com.
  • The effect of probiotics as a treatment for constipation in elderly people: A systematic review - Arch Gerontol Geriatr. 2017 Jul;71:142-149 - "Overall, our analysis of the randomised and placebo-controlled trials suggests that administration of probiotics significantly improved constipation in elderly individuals by 10-40% compared to placebo controls in which no probiotic was administered" - [Nutra USA] - See probiotic products at Amazon.com.
  • Efficacy of Synbiotics in Patients with Slow Transit Constipation: A Prospective Randomized Trial - Nutrients. 2016 Sep 28;8(10) - "A total of 100 patients with slow transit constipation were randomized to receive either a synbiotic or placebo twice daily for 12 weeks ... Over 12 weeks, 64.6% of the patients who received the synbiotic experienced clinical improvement, compared to 29.2% of the patients in the placebo group (p < 0.01). During the intervention period, patients who were treated with the synbiotic exhibited increased stool frequency, improved stool consistency, decreased CTT, and improved constipation-related symptoms" - [Nutra USA] - See synbiotic products at Amazon.com, probiotic products at Amazon.com and inulin at Amazon.com.
  • Effect of the probiotic strain Bifidobacterium animalis subsp. lactis, BB-12®, on defecation frequency in healthy subjects with low defecation frequency and abdominal discomfort: a randomised, double-blind, placebo-controlled, parallel-group trial - Br J Nutr. 2015 Sep 18 - "The OR for having a defecation frequency above baseline for ≥50 % of the time was 1.31 (95 % CI 0.98, 1.75), P=0.071, for probiotic treatment overall. Tightening the criteria for being a responder to an increase of ≥1 d/week for ≥50 % of the time resulted in an OR of 1.55 ... A treatment effect on average defecation frequency was found (P=0.0065), with the frequency being significantly higher compared with placebo at all weeks for probiotic treatment overall (all P<0.05). Effects on defecation frequency were similar for the two doses tested, suggesting that a ceiling effect was reached with the one billion dose. Overall, 4 weeks' supplementation with the probiotic strain BB-12® resulted in a clinically relevant benefit on defecation frequency" - [Nutra USA] - See probiotic products at Amazon.com.
  • ‘Level 1’ evidence that probiotics boost ‘transit time’: Danisco & Fonterra - Nutra USA 6/22/11 - "the benefits were “at least equivalent to that of dietary fiber” ... The researchers recruited 100 healthy people with an average age of 44 and randomly assigned them to receive high or low daily doses of B. lactis HN019, or placebo for 14 days. High dose was defined as 17.2 billion colony forming units (CFU), while the low dose was 1.8 billion CFU ... At the end of the study results showed an improvement in transit time in the high dose group of 33 percent, and 25 percent in the low dose group. There was no change in the placebo group, added the researchers" - [Abstract] - See probiotics at Amazon.com.
  • Probiotics may ease bowel movements for elderly: Study - Nutra USA, 5/13/11 - "The probiotic product (VSL Pharmaceuticals) reportedly contained 450 billion viable lyophilized bacteria from eight different strains, including Lactobacillus plantarum, L. paracasei, L. bulgaricus, L. acidophilus, Bifidobacterium breve, B. longum, B. infantis, and Streptococcus thermophilus ... people consuming the probiotic experienced a lower incidence of diarrhea (60 percent lower), compared to placebo ... In addition, laxative use decreased by 26 percent amongst people in the probiotic group, compared to placebo, added the Israeli scientists ... A significant reduction of Clostridium difficile prevalence was found in the probiotic group" - [Abstract] - See probiotics at Amazon.com.
  • The safety of daily magnesium oxide treatment for children with chronic constipation - Science Daily, 3/8/11 - "The authors concluded that serum magnesium concentrations increase significantly after daily magnesium oxide intake, but the magnitude of the increase appears modest. Younger age, but not prolonged use of daily magnesium oxide might be a relative risk factor, and it should be determined by further studies whether serum magnesium concentration should be assessed in these subjects"
  • Is Bifidobacterium breve effective in the treatment of childhood constipation? Results from a pilot study - Nutr J. 2011 Feb 23;10(1):19 - "Probiotics are increasingly used in the treatment of functional gastrointestinal disorders. Studies in constipated adults with a Bifidus yoghurt (containing Bifidobacterium breve, Bifidobacterium bifidum and Lactobacillus acidophilus) showed a significant increase in defecation frequency ... The defecation frequency per week significantly increased from 0.9 (0-2) at baseline to 4.9 (0-21) in week 4 (p< 0.01). The mean stool consistency score increased from 2.6 (2-4) at baseline to 3.5 (1-6) in week 4 (p = 0.03). The number of faecal incontinence episodes per week significantly decreased from 9.0 (0-35) at baseline to 1.5 (0-7) in week 4 (p <0.01). Abdominal pain episodes per week significantly decreased from 4.2 (0-7) at baseline to 1.9 (0-7) in week 4 (p = 0.01). No side effects occurred" - See Bifidobacterium breve products at iHerb.
  • Fermented milk containing Lactobacillus casei strain Shirota reduces incidence of hard or lumpy stools in healthy population - Int J Food Sci Nutr. 2011 Feb 15 - "Healthy subjects with Bristol Stool Form Scale (BS) score < 3.0 were randomized to fermented milk treatment for 3 weeks or non-intervention control. The primary endpoint was the proportion of subjects that produced hard or lumpy stools (HLS) ≥ 25% of bowel movements (H-HLS). Secondary endpoints included changes in BS score, constipation-related symptom scores and stool parameters. Efficacy was analyzed in 39 subjects. After 3 weeks of treatment the proportion of H-HLS subjects had significantly decreased from 73.7% to 36.8%, whereas in the control group the proportion had increased from 75.0% to 85.0% during the same period (P = 0.002). The BS score was significantly improved after the treatment compared with the control (P < 0.001). In conclusion, daily consumption of fermented milk containing LcS reduced the incidence of HLS" - See Garden of Life, Primal Defense, HSO Probiotic Formula, 180 + 36 = 216 Caplets at iHerb which includes the Lactobacillus casei strain.
  • The Use of Probiotics in Healthy Volunteers With Evacuation Disorders and Hard Stools: A Double-blind, Randomized, Placebo-controlled Study - J Clin Gastroenterol. 2010 Aug 6 - "Subjects treated with the mixed probiotic strains L. plantarum LP01 and B. breve BR03 or B. animalis subsp. lactis BS01 reported a significant improvement in the number of weekly bowel movements and in the main troubles associated with evacuations, particularly consistency of feces and ease of expulsion. Discomfort items such as abdominal bloating and anal itching, burning, or pain also registered a relevant improvement in the active groups receiving probiotics" - See probiotics at Amazon.com.
  • Probiotics work out against constipation, says study - Nutra USA, 8/10/07 - "the frequency of bowel movements doubled over the weeks following the start of probiotic supplementation, increasing from two per week to 4.2 after two weeks, to 3.8 after four weeks" [Abstract]
  • Natural "Bowel Recipe" More Effective in Reducing Straining - Medscape, 10/23/06 - "A "bowel recipe" consisting of wheat bran, applesauce, and prune juice appears to be more effective than a commercial psyllium fiber supplement in reducing straining in women with pelvic floor dysfunction"
  • My three-year-old daughter suffers from constipation - Dr. Weil, 6/26/03
  • Conquering Constipation -- Naturally? - Dr. Weil, 2/20/03 - "The bowel regulator I recommend most frequently is Triphala, a mixture of three fruits from India from the Ayurvedic tradition, available in capsule form at health food stores" - See iHerb Triphala products.

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