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Home > Anti-aging Research > Bovine Colostrum.

Bovine Colostrum

Specific Recommendations:

News & Research:

  • Is dairy colostrum the key to Olympic success? - Science Daily, 2/24/11 - "bovine colostrum can massively reduce gut permeability -- otherwise known as 'leaky gut syndrome.' Their findings, published in the March issue of the American Journal of Physiology-Gastrointestinal and Liver Physiology, could have positive implications not just for athletes but also for sufferers of heatstroke ... The London School of Medicine and Dentistry looked at athletes who were asked to run for 20 minutes at 80 per cent of their aerobic maximum. At the end of the exercise, changes in the subjects gut leakiness were measured using urine sample -- also determined were changes in the athletes' core temperature. Under standard conditions, gut leakiness had increased by 250 per cent and temperature had risen by 2 degrees. However, when the group were given a drink of dairy colostrum for two weeks before the trial, the rise in gut leakiness was reduced by about 80 per cent, despite the same effort and temperature rise"
  • Bovine colostrum emerges as immunity modulator - HealthLink - "The best quality colostrum is produced organically and is free of pesticides, herbicides, anabolic hormones like rBST, steroids, antibiotics and other chemicals. Not all colostrum products on the market are biologically active due to improper processing through the use of high temperatures and pasteurization or the formation of colostrum into tablets, a method that requires high pressure and generates heat, destroying biological activity."

Abstracts:

  • Prophylactic Application of Bovine Colostrum Ameliorates Murine Colitis via Induction of Immunoregulatory Cells - J Nutr. 2011 Apr 27 - "Herein, we addressed the question whether bovine colostrum, the first milk produced by mammals, is able to prevent dextran sulfate sodium (DSS)-induced colitis in mice ... Following 2 wk of observation, the colons were removed for histologic and immunohistochemical evaluation of inflammation. Flow cytometric phenotyping of leukocyte subsets was performed from peripheral blood, mesenteric lymph nodes, and spleens. Administration of bovine colostrum improved the clinical and histologic severity of colorectal inflammation. Compared with BSA-fed and water-fed controls, BV-20 pretreated mice had significantly less severe weight loss and decreased colon shortening. Beneficial effects were accompanied by redistribution of immunoregulatory, peripheral and splenic γδ TCR(+) cells, and CD11b(+)Gr1(+) cells. Higher colostrum doses did not affect disease activity. In summary, prophylactic administration of colostrum improved clinical symptoms of colorectal inflammation in a well-established mouse model of DSS-induced colitis"
  • Bovine colostrum as a biologic in clinical medicine: A review â Part II: Clinical studies - Int J Clin Pharmacol Ther. 2008 May;46(5):211-25 - "The value of bovine colostrum as a biologic in medicine is documented in clinical trials and supported by relatively large databases containing case reports and anecdotal findings. The main actions include an antibacterial effect and modulation of the immune response. The ability of bovine colostrum concentrates (BCC are polyvalent bovine colostrum concentrates produced from the colostrums of several 100 cows) to neutralize lipopolysaccharides, i.e. endotoxins arising from Gram-negative bacterial pathogens and to inhibit enterogenic endotoxemia in animal models as shown in the last review to have its counterpart in patient therapy"
  • Chemopreventive effects of bovine lactoferrin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat bladder carcinogenesis - Jpn J Cancer Res. 2000 Jun;91(6):582-8 - "Group 1 demonstrated a significantly decreased multiplicity of the bladder tumors (carcinomas and papillomas) as compared with group 3. Maximum cut surface areas of bladder tumors were also significantly decreased in groups 1 and 2 compared with group 3"
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