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Antidepressants & Psychotropics > Zoloft® (sertraline hydrochloride)
Zoloft® (sertraline Hydrochloride)
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News & Research:
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Zoloft (sertraline Hcl) - rxlist.com
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Zoloft - Reuters
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FDA Approves Generic Zoloft -
WebMD, 6/30/06
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Mirtazapine Betters Major SSRIs for Treatment of Depression - Doctor's
Guide, 5/27/05 - "A meta-analysis of
clinical trials involving more than 2,500 subjects suggests that treatment
of depression with mirtazapine (Remeron) results in a more rapid onset of
clinical improvement compared to treatment with fluoxetine, paroxetine, and
sertraline (all SSRIs)" - See Remeron (mirtazapine) at OffshoreRX.com
 .
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Sertraline HCl and Venlafaxine-XR Show Comparable Efficacy in Major Depression - Doctor's Guide, 6/23/04
- Mirtazapine More Effective Than Sertraline On Veterans' Post-Traumatic Stress Disorder - Doctor's Guide, 10/14/03
- Sertraline Shows Short-Term Safety, Efficacy for Major Depressive Disorder in Children and Adolescents - Doctor's Guide, 8/26/03
- Zoloft Effective in Childhood Depression - WebMD, 8/26/03
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Sertraline May Enhance Antiplatelet Activity in Patients With Acute Coronary Syndromes - Doctor's Guide, 8/19/03
- Long-Term Sertraline Effective in Treating Obsessive-Compulsive Disorder in Children and Adolescents - Doctor's Guide, 8/11/03
- Antidepressant May Prevent Blood Clots - WebMD, 8/11/03
- Zoloft Safely Treats Depression in People with Alzheimer's Disease - WebMD, 7/29/03
- Sertraline Is Effective in Treatment of Depression of Older Adults - Doctor's Guide, 7/21/03
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Sertraline: Less Postpartum Depression Recurrence - Clinical Psychiatry News, 6/03
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Sertraline Associated with Cognitive and Behavioural Improvements in Mild Alzheimer's Disease - Doctor's Guide, 5/17/03
- Patients with Non-melancholic Depression Might Respond Better to Sertraline than Imipramine - Doctor's Guide, 4/17/03
- Combining Prolonged Exposure With Sertraline Enhances Drug Benefits of Post Traumatic Stress Disorder - Doctor's Guide, 4/1/03
- Sertraline Equally Effective In Men And Women With Generalized Anxiety Disorder - Doctor's Guide, 4/1/03
- Sertraline Treats Psychic Anxiety Symptoms Associated with a Range of Depressive and Anxiety Disorders - Doctor's Guide, 4/1/03
- Sertraline Improves Quality of Life in Patients With Generalized Anxiety Disorder - Doctor's Guide, 4/1/03
- Sertraline Effective for Treating Social Anxiety Disorder - Doctor's Guide, 3/31/03
- Sertraline Better Tolerated than Paroxetine in Panic Disorder - Doctor's Guide, 3/30/03
- Sertraline May Not Reduce Cognitive Deficits in Elderly Patients with Depression and Cognitive Impairment - Doctor's Guide, 3/4/03
- FDA Approves Zoloft (Sertraline) For Treatment Of Social Anxiety Disorder - Doctor's Guide, 2/11/03
- SSRIs May Increase Risk of Gastrointestinal Bleeding - Medscape, 1/17/03 -
"Selective serotonin reuptake inhibitors (SSRIs) are associated with
an increased risk of gastrointestinal (GI) bleeding, especially when combined with nonsteroidal anti-inflammatory drugs (NSAIDs)" - Examples of SSRIs are
Prozac, Paxil and Zoloft.
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Pfizer Issues Warning on Sertraline + Pimozide - Clinical Psychiatry News, 1/03
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Long-Term Sertraline Effective, Safe in Children - Clinical Psychiatry News, 1/03
- Luteal Phase Sertraline Curbs Premenstrual Dysphoric Disorder - Doctor's Guide, 12/23/02
- Sertraline Helpful in Premenstrual Dysphoric Disorder - Medscape, 12/9/02
- Mirtazapine May Be Superior to Sertraline in Onset Time, Symptom Reduction among Patients with Major Depression - Doctor's Guide, 11/4/02
- Twice A Day Sertraline Effective In Adolescents - Doctor's Guide, 10/22/02
- Setraline Effective, Safe for Major Depression in Children - Doctor's Guide, 10/11/02
- Sertraline Effective, Well-Tolerated in Geriatric Patients With and Without Comorbidity - Doctor's Guide, 10/9/02
- Sertraline Effective For Premature Ejaculation In Some Men - Doctor's Guide, 9/30/02
- Sertraline Effective for Major Depression in Patients with Acute Myocardial Infarction or Unstable Angina - Doctor's Guide, 8/14/02
- Sertraline Safe, Effective in Patients With Recent MI, Angina - Medscape, 8/14/02
- Study Suggests Anti-Depressant Is Safe In Some Heart Patients - Intelihealth, 8/13/02
- High-Dose Sertraline Effective for Obsessive-Compulsive Disorder when Lower Doses Fail - Doctor's Guide, 6/28/02
- Sertraline May Prevent Depression and Improve Cognitive Function within One Year of Stroke - Doctor's Guide, 6/27/02
- Sertraline Improves Symptoms and Quality of Life in Patients with Moderate to Severe Social Phobia - Doctor's Guide, 6/26/02
- Sertraline May Be Safe and Effective for Moderate to Severe PMS - Doctor's Guide, 6/26/02
- St. John's Wort as Effective as Zoloft® against Depression - New Hope Natural Media Online, 6/13/02 -
"St. John's wort (SJW), a popular herbal
remedy, is at least as effective as the prescription drug sertraline (Zoloft®) in the treatment of depression and causes fewer side effects, according to a new study published in Canadian Family Physician (2002;48:905–8). This report confirms dozens of other studies demonstrating
SJW is an effective treatment for mild-to-moderate depression, and contradicts two controversial studies suggesting the herb is of little or no benefit ... After 12 weeks, the severity of depression had decreased by an average of 50.2% in the SJW group and by 41.6% in the sertraline group"
- Sertraline Effects Differ in Depressed Women - Doctor's Guide, 6/6/02 -
"The investigators say four-week sertraline
therapy increased plasma cortisol levels in the depressed patients"
- Sertraline Effective for Generalized Anxiety Disorder - Doctor's Guide, 5/22/02
- Sertraline Beats Fluoxetine for Severe Depression - Doctor's Guide, 5/22/02
- Results From A New Study Show Zoloft (Sertraline) Effective In Treatment Of Social Anxiety Disorder - Doctor's Guide, 5/21/02
- Zoloft (Sertraline HCl) Receives FDA Approval For Treatment Of Premenstrual Dysphoric Mood Disorder - Doctor's Guide, 5/21/02
- St. John's Wort: Effective, with Caveats - Nutrition Science News, 3/02 -
"Using the Hamilton Rating Scale for Depression, 47 percent of those taking
St. John's wort improved compared with 40 percent of those taking the sertraline ... Hyperforin increases the effectiveness of norepinephrine, dopamine, L-glutamate, and
gamma-amino butyric acid (GABA), as well as serotonin. Researchers in the Department of Pharmacology at the University of Frankfurt in Germany concluded, "no other
antidepressant compound exhibits a similar broad uptake-inhibiting profile.""
- Sertraline Impact on Platelets Appears to Explain Reduction of Cardiovascular Events - Doctor's Guide, 3/18/02
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Long-Term Sertraline Improves Pediatric OCD - Clinical Psychiatry News, 2/02
- Research Fails to Uncover Factors to Predict Response to Sertraline for Social Phobia - Doctor's Guide, 11/18/01
- Depression After an Acute Coronary Syndrome Improves with Sertraline - Doctor's Guide, 11/12/01
- FDA Approves Zoloft (Sertraline) For Long-Term Use in Post-Traumatic Stress Disorder - Doctor's Guide, 8/16/01
- Sertraline And Imipramine Reduce Anxiety In Depressed Patients - Doctor's Guide, 3/15/01
- Zoloft (Sertraline) Significantly Reduces Posttraumatic Stress Disorder Symptoms - Doctor's Guide, 4/12/00
- Sertraline Effective For Adolescent Anxiety Disorders - Doctor's Guide, 10/22/99
Abstracts:
- Double-blind Switch Study of Imipramine or Sertraline Treatment of Antidepressant-Resistant Chronic Depression - Archives of General Psychiatry, 3/02
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Comparison of an extract of hypericum (LI 160) and sertraline in the treatment of depression: a double-blind, randomized pilot study - Medline/Clin Ther 2000 Apr;22(4):411-9, 4/00 -
"Clinical response (defined as a > or =50% reduction in HAM-D scores) was noted in 47% of patients receiving hypericum and 40% of those receiving sertraline ... The [LI 160] hypericum extract was at least as effective as sertraline in the
treatment of mild to moderate depression in a small group of outpatients"
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