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Home > Anti-aging Research > Antidepressants > Tricyclics


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  • Long-Term Use of Antidepressants for Depressive Disorders and the Risk of Diabetes Mellitus - Am J Psychiatry. 2009 Apr 1 - "Compared with no use of antidepressants during the past 2 years, recent long-term use (>24 months) of antidepressants in moderate to high daily doses was associated with an increased risk of diabetes (incidence rate ratio=1.84, 95% CI=1.35-2.52). The magnitude of the risk was similar for long-term use of moderate to high daily doses of tricyclic antidepressants (incidence rate ratio=1.77, 95% CI=1.21-2.59) and selective serotonin reuptake inhibitors (incidence rate ratio=2.06, 95% CI=1.20-3.52)"

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